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Manifestasi Kulit Pada Pasien Diabetes Melitus: Systematic Review Bhelqis, Qherine; Melita, Nina; Zulissetiana, Eka Febri
JURNAL PENELITIAN PENDIDIKAN, PSIKOLOGI DAN KESEHATAN (J-P3K) Vol 5, No 3 (2024): J-P3K DESEMBER
Publisher : Yayasan Mata Pena Madani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51849/j-p3k.v5i3.488

Abstract

Diabetes melitus merupakan penyakit metabolik yang ditandai dengan hiperglikemia kronik dengan angka kejadian yang diperkirakan akan terus meningkat. Komplikasi yang ditimbulkan oleh diabetes melitus dapat menyebabkan ancaman jiwa apabila tidak ditangani dengan cepat sehingga diperlukan upaya untuk mengenali secara dini penyakit diabetes melitus untuk mencegah komplikasi lebih lanjut. Penelitian ini bertujuan untuk mengetahui gambaran kulit pada pasien diabetes melitus sehingga dapat memberikan informasi penting sebagai indikasi adanya diabetes melitus serta mencegah komplikasi. Hasil pencarian didapatkan 457 artikel, dengan total 8 artikel terpilih yang relevan dengan studi sesuai dengan kriteria inklusi. Ditemukan angka infeksi jamur pada diabetes melitus tergolong cukup tinggi, diikuti oleh infeksi bakteri dan virus. Manifestasi kulit yang beragam termasuk dermopati diabetik, akantosis nigrikans, ulkus diabetikum, xerosis, idiopathic hypomelanosis guttate, necrobiosis lipoidica diabeticorum, dan skin tag juga ditemukan pada diabetes melitus.
Mitochondrial Dynamics: An Attractive Therapeutic Target for Ischemia-Reperfusion Injury in the Heart Rosdah, Elisha Rosalyn; Zulissetiana, Eka Febri; Rosdah, Ayeshah Augusta
Molecular and Cellular Biomedical Sciences Vol 8, No 3 (2024)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v8i3.487

Abstract

Myocardial infarction is one of the leading causes of death worldwide. Current treatments do not compensate for the loss of cardiomyocytes, thus progression to heart failure is often inevitable. In myocardial infarction, the occlusion of coronary arteries and sudden restoration of blood flow give rise to ischemia-reperfusion injury, which leads to cardiomyocyte death. Mitochondria are not only involved in the bioenergetic aspect of the heart but also play a pivotal role in cell death during ischemia-reperfusion injury. Their morphology dynamically changes via fusion and fission in a balanced manner to maintain cellular health. However, ischemia-reperfusion injury triggers excessive mitochondrial fission, which is pathological to the myocardium. This review article discusses the association between myocardial ischemia-reperfusion injury and mitochondrial dynamics, serving as a rationale for a novel therapeutic strategy for myocardial infarction. Strategic modulation of mitochondrial dynamics under this pathological setting has been shown to be effective for cardioprotection. Increasing mitochondrial fusion or reducing excessive mitochondrial fission in the myocardial tissue could prevent cardiomyocyte death, thereby reducing infarct size. Proof-of-concept studies have utilized small molecules and peptides to implement this strategy into in vivo myocardial ischemia-reperfusion injury models. However, there remains a need to address the issues of specificity, bioavailability, and potency of these pharmacological agents before future application in cardiovascular therapeutics. Nevertheless, there has been growing interest in this therapeutic strategy in recent years, rendering it an attractive approach for ischemia-reperfusion injury in the heart.Keywords: mitochondria, heart, ischemia-reperfusion, cardioprotection
THE RELATIONSHIP BETWEEN HIGH GLYCEMIC INDEX DIET AND MUSCULOSKELETAL DISORDERS Adinda, Adinda; Legiran; Arwan Bin Laeto; Ayeshah Augusta Rosdah; Eka Febri Zulissetiana; Kamalia Layal
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 12 No. 1 (2025): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Univers
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v12i1.552

Abstract

Musculoskeletal disorders include acute and chronic conditions affecting the muscles, bones, joints, and supporting structures in the neck, back, and limbs, posing significant challenges across all age groups. Approximately 30% of cases occur in adolescents and individuals in their productive years, not just in the elderly. These disorders lead to substantial socioeconomic and health burdens. Previous research indicates that dietary patterns play a critical role in the onset and progression of these conditions. A persistent high-glycemic index (GI) diet is associated with systemic inflammation, metabolic dysregulation, and musculoskeletal health. This study aims to provide a comprehensive review of existing literature to summarize and identify the potential relationship between high-GI diets and the prevalence of musculoskeletal disorders (MSDs). Articles were collected using search engines such as PubMed, Medscape, and ScienceDirect, focusing on publications from 2013 to 2024. The findings emphasize the importance of dietary interventions as modifiable risk factors for preventing and managing musculoskeletal disorders, particularly in at-risk populations. Further studies are needed to develop dietary strategies to reduce the global burden of musculoskeletal disorders effectively.
Analysis of the musculoskeletal pain risk profile through observation of work posture in minimarket employees Laeto, Arwan Bin; Putri, Siti Sarahdeaz Fazzaura; Agustine, Vania; Hasbi, Alfian; Zulissetiana, Eka Febri
Journal of Health Management and Pharmacy Exploration Vol. 3 No. 1 (2025): February 2025
Publisher : Surya Hijau Manfaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52465/johmpe.v3i1.549

Abstract

Musculoskeletal pain refers to the discomfort experienced in the musculoskeletal system as a result of various pain-inducing factors. Musculoskeletal pain is a leading cause of disability and absenteeism in the workplace. The primary causes of declining health among workers include occupational injuries (29.5%), overtime (25.9%), and ergonomic factors (13.7%), significantly influence occupational health and can adversely affect organ function. The study was conducted through observational approach with a cross-sectional design and primary data collected using the Nordic Body Map (NBM) questionnaire and the Rapid Entire Body Assessment (REBA). The study population is mini market employees and sample comprises were employees who fulfil inclusion and exclusion criteria as many as 50 respondents by using non-probability sampling technique. The results of study were obtained that the majority of workers belong to the age group of under 35 years, as many as 49 individuals (98%) and more than half of the respondents are predominantly female, accounting for 52% of the total. Furthermore, the study indicates that the dominant "Very Painful" predilection criterion is most frequently reported in the back and waist of the respondents, accounting for 40% of the total respondents. Next, the majority of minimarket workers exhibit a moderate level of risk in their work posture, with 21 individuals (42%) falling into this category. Based on the results, it is recommended that respondents engage more actively in physical exercise and massage therapy.
HUBUNGAN KOMPOSISI TUBUH DAN TINGKAT AKTIVITAS FISIK DENGAN KEJADIAN NYERI MUSKULOSKELETAL PADA PEKERJA MINIMARKET Hasbi, Alfian; Laeto, Arwan Bin; William, Jessica Audrey; Zulissetiana, Eka Febri; Santoso, Budi
ASSYIFA : Jurnal Ilmu Kesehatan Vol. 3 No. 1 (2025)
Publisher : Forind Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62085/ajk.v3i1.129

Abstract

Musculoskeletal pain is acute or chronic pain, either persistent or recurring, that affects bones, muscles, ligaments, tendons, and nerves. According to Riset Kesehatan Dasar tahun 2018, the prevalence of musculoskeletal diseases in Indonesia has reached 7,3%. One of the risk factors is body composition and physical activity. This study aims to determine the relationship between body composition and physical activity with musculoskeletal pain among minimarket workers in Palembang City. An observational analytic study with a cross-sectional design was conducted on 50 respondents. Body composition was measured using Bioelectrical Impedance Analysis, while data on physical activity levels and musculoskeletal pain were collected using the International Physical Activity Questionnaire-Short Form and the Nordic Body Map Questionnaire. The study results show that the majority of minimarket workers had overfat body composition (32%); moderate physical activity levels (46%); and low risk of musculoskeletal pain (38%), with the most common areas of pain were the back and waist (40%). Bivariate analysis using Pearson’s Chi-Square test between body composition and musculoskeletal pain showed PR = 15.625 and p-value < 0.001. Meanwhile, the analysis of physical activity levels and musculoskeletal pain showed PR = 2.311 and p-value = 0.166. Thus, there is a significant relationship between body composition and musculoskeletal pain. However, there is an insignificant relationship between physical activity levels and musculoskeletal pain among minimarket workers in Palembang City.
Program Pendampingan Stimulasi dan Pijat Pada Bayi dan Balita Dalam Upaya Mengoptimalkan Pertumbuhan dan Perkembangan Eka Febri Zulissetiana; Susilawati, Susilawati; Nurwany , Raissa; Hasbi, Alfian; Kurniato, Andra; Alkaf, Syifa
JPNM Jurnal Pustaka Nusantara Multidisiplin Vol. 3 No. 2 (2025): July : Jurnal Pustaka Nusantara Multidisiplin
Publisher : SM Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59945/jpnm.v3i2.428

Abstract

Usia 0 – 24 bulan adalah periode penting dalam pertumbuhan dan perkembangan karena pada masa ini anak akan bertumbuh kembang secara optimal untuk perkembangan kognitif dan fisik. Stimulasi adalah kegiatan merangsang kemampuan dasar anak umur 0-6 tahun agar anak tumbuh dan berkembang secara optimal. Pijat biasa disebut dengan stimulus touch atau sentuhan. Pijat bayi dan balita dapat diartikan sebagai sentuhan komunikasi yang nyaman antara ibu dan bayi/ balita.. Jika tindakan ini dilakukan secara teratur, maka sentuhan ini dapat merupakan bentuk stimulasi dan intervensi yang dapat memberikan banyak manfaat untuk anak. Pemberian edukasi dan pendampingan serta pemberdayaan pendamping bayi dan balita serta kader posyandu untuk melakukan stimulasi dan pijat secara rutin merupakan strategi yang tepat untuk mendampingi pola asuh dalam rangka meningkatkan dan mengoptimalkan pertumbuhan dan perkembangan pada bayi dan balita. Kegiatan pengabdian masyarakat ini dilakukan kepada 68 orang pendamping bayi dan balita serta 20 orang kader posyandu di wilayah Puskesmas 7 Ulu Kota palembang berupa pemberian penyuluhan dan edukasi. Kegiatan juga disertai upaya pendampingan kepada para kader posyandu agar untuk selanjutnya dapat memberikan edukasi secara rutin. Penilaian keberhasilan pengabdian masyarakat ini dilakukan dengan menilai peningkatan pengetahuan peserta sebelum dan sesudah kegiatan dan tercapainya target frekuensi untuk semua peserta selama sesi kegiatan. Dari kegiatan pengabdian masyarakat ini, dapat disimpulkan bahwa Kegiatan penyuluhan dan pendampingan dapat dilakukan untuk meningkatkan pengetahuan dan pembiasaan para pendamping bayi dan balita dalam melakukan stimulasi dan pijat bayi dan balita.
Help-seeking Behavior of Disorders of Sex Development Patients in Palembang, Indonesia Khairunnisa, Tyas Citra; Maritska, Ziske; Purnamasari, Septi; Zulissetiana, Eka Febri; Inggarsih, Rara
Biomedical Journal of Indonesia Vol. 11 No. 2 (2025): Vol 11, No 2, 2025
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v11i2.220

Abstract

Introduction. Disorders of Sex Development (DSD) is a congenital disorder in which there is atypical chromosomal, gonadal, or anatomical sex development. Children with DSD are often brought to the hospital too late for care due to limited knowledge about this condition among medical practitioners. Early diagnosis is important to improve prognosis and minimize complications and comorbidities of DSD patients. Methods. This study is a descriptive observational study with a cross-sectional approach through interviews and data collection from medical records of Dr. Mohammad Hoesin Palembang Hospital in 2020 - 2023. Results. In this study, it was found that the infancy age group (28 days - 1 year) was the most common age of arrival of patients to the hospital (29%) and the most common main complaint was clitoral enlargement (19.4%). Conclusion. This study found a wide variation in patients’ chief complaints, which makes the age of arrival of DSD patients to the hospital still quite late.
Physical Activity Impact on Severity of Dysmenorrhea among Junior High School Students: A Cross Sectional Study Raissa Nurwany; Nadhira Tsurayya Ramadhani; Siti Sarahdeaz Fazzaura Putri; Eka Febri Zulissetiana; Arwan bin Laeto; Ardelia Bianda
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 2 April 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i2.2734

Abstract

Objective: This study aims to identify the prevalence of dysmenorrhea, the level of physical activity, the risk factors for dysmenorrhea and to determine the relationship between physical activity and the severity of dysmenorrhea among junior high school students. Method: This is a cross-sectional, observational analytical study on the population of adolescence, junior high school students, conducted from July to December 2023 in Palembang. Primary data were obtained using Physical Activity Questionnaire for Older Children (PAQ-C) and working ability, location, intensity, days of pain, dysmenorrhea (WaLIDD) score. Results: About 88.9% of students experienced primary dysmenorrhea, with 34.4% experiencing mild dysmenorrhea, 38.9% experiencing moderate dysmenorrhea, and 15.6% experiencing severe dysmenorrhea. The level of daily physical activity performed by the students was 43.3% low activity, 55.6% moderate activity, and 1.1% high activity. There was no significant relationship between physical activity and the degree of dysmenorrhea (p=0.459; PR=0.828; 95% CI: 0.558-1.230). Menarche age <12 years (PR=1.186), a family history of dysmenorrhea (PR=1.225), and irregular menstrual cycles (PR=1.283) are risk factors for higher degree of dysmenorrhea. Conclusion: There is no relationship between physical activity and the degree of dysmenorrhea. Female students mostly experience moderate primary dysmenorrhea, with the dominant level of physical activity being moderate. Menarche age <12 years, a family history of dysmenorrhea, and irregular menstrual cycles are risk factors for the higher degree of dysmenorrhea. Keywords: Adolescents, primary dysmenorrhea, physical activity
Prevalence and Risk Factors of Emotional Mental Disorder Among University Students: A Cross-Sectional Study Habibah, Umrohtul; Syakurah, Rizma Adlia; Aini, Syarifah; Ikhsan, Diyaz Syauki; Zulissetiana, Eka Febri
Jurnal Psikologi Integratif Vol. 13 No. 1 (2025): Psikologi Integratif
Publisher : UIN Sunan Kalijaga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/jpsi.v13i1.3177

Abstract

Emotional mental health issues among university students have shown an increasing trend over time, reaching concerning levels when compared to the general population. Early detection is very important for the university as an early intervention to improve students’ mental health. This study used an analytic observational design with a cross-sectional approach. A total of 1564 students from 10 faculties of Sriwijaya University filled in the SRQ-29 questionnaire online via social media from January 2020 – 27 August 2020.  The obtained data were analyzed using the Mann Whitney, Chi-Square, and Binary Logistic Regression Test with a significance value of p<0.05. As much as 56.6% of the students experienced symptoms of neurosis, 75.6% had symptoms of PTSD, 55% had psychotic symptoms, while 1.2% had symptoms of substance abuse. Students with a history of chronic disease are more susceptible to experience emotional mental disorders (86%). Gender, faculty, domicile, history of chronic disease and history of mental disorders in the family significantly affected emotional disorders (p <0.05). Universities need to provide mental health facilities that are managed by professionals and ensure the confidentiality of data in their environment.Permasalahan kesehatan mental emosional di kalangan mahasiswa menunjukkan kecenderungan yang semakin meningkat dari waktu ke waktu, bahkan pada tingkat yang mengkhawatirkan jika dibandingkan dengan populasi umum. Deteksi dini sangat penting bagi universitas sebagai intervensi dini untuk meningkatkan kesehatan mental mahasiswa. Penelitian ini menggunakan desain observasional analitik dengan pendekatan cross sectional. Sebanyak 1564 mahasiswa dari 10 fakultas Universitas Sriwijaya mengisi kuesioner SRQ-29 secara online melalui media sosial dari Januari 2020 – 27 Agustus 2020. Data yang diperoleh dianalisis menggunakan Mann Whitney, Chi-Square, dan Uji Regresi Logistik Biner dengan nilai signifikansi p<0,05. Sebanyak 56,6% siswa mengalami gejala neurosis, 75,6% mengalami gejala PTSD, 55% mengalami gejala psikotik, sedangkan 1,2% mengalami gejala penyalahgunaan zat. Mahasiswa dengan riwayat penyakit kronis lebih rentan mengalami gangguan mental emosional (86%). Jenis kelamin, fakultas, domisili, riwayat penyakit kronis dan riwayat gangguan jiwa dalam keluarga berpengaruh signifikan terhadap gangguan emosi (p<0,05). Perguruan tinggi perlu menyediakan fasilitas kesehatan jiwa yang dikelola secara profesional dan menjamin kerahasiaan data di lingkungannya.
Consumption of Sugar-Sweetened Beverages Is Related to Fasting Blood Glucose and the Nutritional Status among Young Adults in Indonesia Syahranni, Dhanya; Kurniati, Ardesy Melizah; Liberty, Iche Andriyani; Husin, Syarif; Zulissetiana, Eka Febri
Althea Medical Journal Vol 12, No 3 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v12n3.4139

Abstract

Background: Habitual consumption of sugar-sweetened beverages (SSBs) is linked to elevated blood glucose and increased body weight. Medical students often experience high stress, which may increase SSBs consumption. This study aimed to examine the associations between SSB consumption, fasting blood glucose, body mass index (BMI), and waist circumference among medical students.Methods: A cross-sectional study was conducted in October 2022 using a total sampling method involving 184 first-year students at the Faculty of Medicine Universitas Sriwijaya, Palembang, Indonesia. SSBs consumption was assessed using a semi-quantitative food frequency questionnaire (SQ-FFQ). Fasting blood glucose was measured by  glucometer after an overnight fast. Body height, weight, and waist circumference were measured using a stadiometer, digital scale, and tape measure, respectively. Physical activity was assessed with the International Physical Activity Questionnaire–Short Form (IPAQ-SF). Associations were tested using Kruskall Wallis, independent t-test, and chi square as appropriate.Results: Most students consumed SSBs 3–4 times per week and in amount >495 mL. The volume of SSBs consumption was associated with BMI (p=0.02), fasting blood glucose (p<0.001), and waist circumference (p<0.01). Similarly, the frequency of SSBs consumption was associated with fasting blood glucose (p=0.04) and waist circumference (p<0.01), but not with BMI (p=0.16). Conclusion: Consumption of SSBs among students is high. Frequent and high-volume consumption of SSBs is associated with elevated fasting blood glucose levels and the nutritional status, whereas higher volume is associated with increased BMI. Reducing SSB intake and promoting healthier beverage choices may support a sustainable healthy lifestyle in young adults.