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All Journal Pharmaciana: Jurnal Kefarmasian JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Al Ishlah Jurnal Pendidikan Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) Jurnal Ilmu Kefarmasian Indonesia Pharmaceutical Journal of Indonesia Lumbung Farmasi : Jurnal Ilmu Kefarmasian Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Jurnal Informatika Progres FARMASAINKES Bangun Desa : Jurnal Pengabdian Masyarakat Journal of Psychological Research
Kusumawardani, Nurul
Program Studi S1 Farmasi; Fakultas Ilmu-Ilmu Kesehatan; Universitas Alma Ata
Religion Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Analysis of total phenolic content and antioxidant activity of mahogany seed infusion (Swietenia mahagoni (L.) Jacq.) Pratiwi, Sindi; Emelda, Emelda; Kusumawardani, Nurul; Munir, Muhammad Abdurrahman; Azizah, Abibatul; Pothitirat, Werayut
Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) VOLUME 12 ISSUE 4, 2024
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/ijnd.2024.12(4).262-272

Abstract

Background: The mahogany plant (Swietenia mahagoni) is a plant used in medicine. Mahogany seeds are also efficacious as antiseptics, antioxidants, and antimicrobials. This plant contains flavonoids, saponins, tannins, essential oils, alkaloids, and anthraquinones. The higher the phenolic content in a plant, the higher the antioxidant activity. According to previous studies, it was stated that the methanol extract of mahogany seeds has good antioxidant properties, and the phenolic compounds contained in mahogany seeds can be the main contributors to antioxidant activity.Objectives: This study aims to analyze the total phenolic content, measure the inhibition concentration 50% (IC50) and determine the antioxidant activity of mahogany (Swietenia mahagoni) seed infusion.Methods: This type of research is experimental which begins with extraction using the infusion method at a temperature of 900C for 15 minutes followed by measuring the total phenolic content by reacting the infusion preparation and the Gallic acid respectively with the Follin-ciocalteu reagent. The antioxidant activity test was carried out using the DPPH (,-diphenyl--picrylhydrazyl) free radical scavenging method. Each absorbance was measured using UV-Vis Spectrophotometry. The phenolic test was measured by making a linear regression between concentration and absorbance, followed by calculating the total phenolic content. Meanwhile, the absorbance obtained for the antioxidant test was calculated by calculating the percent inhibition. The IC50 is determined by calculating the linear regression of the relationship between concentration and percent inhibition.Result: The results of the phenolic content were 2.531 ± 0.029 mg GAE/g, the IC50 value for gallic acid was 5.54 ppm, and for mahogany seed extract, the IC50 value was 47.04 ppm, which is a very strong antioxidant.Conclusion: This study concluded that the phenolic content of mahogany seed infusion extract contained phenolic compounds equivalent to 2.531 ± 0,029 mg GAE/g of gallic acid and that mahogany seed extract had very strong antioxidant activity.
KUALITAS HIDUP PASIEN GAGAL GINJAL KRONIS DENGAN KOMORBID DIABETES MELITUS YANG MENJALANI HEMODIALISIS Fauziyah, Laiza Nurannisa; Ananda, RA Dewinta Sukma; Kusumawardani, Nurul; Estiningsih, Daru
JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 5 No. 2 (2026): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v5i2.6284

Abstract

Gagal Ginjal Kronik (GGK) merupakan salah satu penyakit kronis yang prevalensinya terus meningkat secara global. salah satunya di Indonesia. Kondisi ini memiliki kaitan erat dengan komorbid Diabetes Melitus (DM). DM sebagai komorbid mempengaruhi kualitas hidup pasien. sehingga pengukuran kualitas hidup dapat membantu mengidentifikasi aspek yang terganggu dan mengukur efektivitas terapi jangka panjang yang dijalani oleh pasien. Oleh karena itu. penelitian ini bertujuan untuk mengetahui hubungan antara komorbid DM dengan kualitas hidup pasien GGK yang menjalani hemodialisis. Desain penelitian cross-sectional dengan pendekatan observasional kuantitatif. Populasi penelitian ini sebanyak 122 responden. dengan sampel yang diambil sebanyak 104 responden dengan teknik purposive sampling yang telah memenuhi kriteria inklusi dan eksklusi. Data sosiodemografi dan klinis dikumpulkan melalu Case Report Form (CRF) dan rekam medis. sedangkan kualitas hidup dinilai menggunakan kuesioner EQ-5D-3L. Hasil penelitian ini menunjukkan bahwa sebagian besar responden dengan komorbid DM memiliki masalah pada domain mobility (29.7%) dan self-care (18.9%). yang mencerminkan keterbatasan fisik dan ketergantungan dalam aktivitas sehari-hari. Analisis uji chi-square. menunjukkan adanya hubungan signifikan (p=0.021<0.05) antara komorbid DM dengan kualitas hidup pasien GGK (OR=1.408; 95%CI=1.017-1.951). Disimpulkan bahwa terdapat hubungan antara komorbid DM dan kualitas hidup pasien GGK yang menjalani hemodialisis. di mana pasien dengan DM cenderung memiliki kualitas hidup lebih rendah. terutama pada aspek mobilitas dan perawatan diri. Diperlukan edukasi. rehabilitasi. dan dukungan psikososial untuk meningkatkannya
KLASIFIKASI TANAMAN OBAT TRADISIONAL BERBASIS CITRA BUAH DAN DAUN Kusumawardani, Nurul; Danuputri, Chyquitha; Darniati; Faisal, Muhammad; A.M Hayat, Muhyiddin; S. Kuba, Muhammad Syafaat; Anggreani, Desi
PROGRESS Vol 18 No 1 (2026): April
Publisher : P3M STMIK Profesional Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56708/progres.v18i1.534

Abstract

Indonesia is a megabiodiversity country with extensive use of traditional medicinal plants; however, plant identification in natural environments remains largely manual and error-prone. Recent advances in deep learning, particularly Vision Transformer (ViT), provide a promising solution by effectively capturing global spatial features for image classification. This study applies a ViT-Base/16 model to automatically classify fruit and leaf images of Indonesian medicinal plants. The dataset comprises 1,000 field-collected images from Galung Village, West Sulawesi, covering 20 classes (10 medicinal and 10 non-medicinal plants). The model was fine-tuned using the AdamW optimizer with a learning rate of 2×10⁻⁵ and trained for 30 epochs with cosine annealing. The proposed approach achieved high performance, with 99.33% accuracy, 99.41% precision, 99.33% recall, and a 99.33% F1-score, while binary classification between medicinal and non-medicinal plants reached 100% accuracy. The system was deployed as a Flask-based web application, demonstrating reliable functionality and practical response times. Overall, the results confirm the effectiveness of Vision Transformer for medicinal plant classification under natural conditions and highlight its potential to support digital documentation, education, and the preservation of local ethnobotanical knowledge.
Adherence and blood pressure control in hypertensive patients: a cross-sectional study Larasati, Intan Sukma; Nurinda, Eva; Wulandari, Ari Susiana; Kusumawardani, Nurul; Indrayana, Sofyan; Amukti, Danang Prasetyaning
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 24 No. 1 (2026): JIFI In Press
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v24i1.1641

Abstract

In 2023, the prevalence of hypertension in the Special Region of Yogyakarta was  31.8%, with 24% of patients inconsistent adherence to therapy. This study was a cross-sectional study which examined the link between adherence to medication and lifestyle changes with blood pressure control among 120 hypertensive patients in the Hypertension Class Program at Bambanglipuro Primary Health Center using an adherence questionnaire. Most participants exhibited low adherence to both medication (54.2%) and lifestyle interventions (73.3%). The cut-off point for grouping respondents into low and high adherence is based on the median value of the respondents' questionnaire scores (because the data is not normally distributed). Uncontrolled blood pressure was prevalent, with a mean systolic pressure of 151.95±11.45 mmHg and a mean diastolic pressure of 87.14±10.45 mmHg. Spearman's rho analysis revealed a statistically significant relationship between adherence and blood pressure control (p<0.001), with a strong negative correlation observed for medication adherence (r = -0.530) and a moderate negative correlation for lifestyle adherence (r = -0.404). Furthermore, low adherence was associated with a substantially increased risk of uncontrolled blood pressure, with odds ratios of 11.30 (95% CI: 4.70–27.21) for medication adherence and 6.82 (95% CI: 2.77–16.80) for lifestyle adherence. These findings underscore the critical importance of improving patient adherence to both pharmacological and non-pharmacological management strategies to achieve optimal blood pressure control.
Co-Authors . Darniati Ahmad Salim Akrom, Akrom Amalia, Latifa Amukti, Danang Amukti, Danang ANAFRIN YUGISTYOWATI Anggreani, Desi Apristina, Ana Avista, Agriva Devaly Azizah, Abibatul Basuki, Adriyanto Rochmad Danang Prasetyaning Amukti Danuputri, Chyquitha Daru Estiningsih Dwinta, Eliza emelda, emelda Endang Darmawan Endang Darmawan Estiningsih, Daru Eva Nurjanah Fauziyah, Laiza Nurannisa Herlina, Tetie Husnul Khatimah Iftita Nuratika Ramadhanti Indrayana, Sofyan Jasmine Amira Hatisuci Larasati, Intan Sukma Lestari, Masbani Ajeng Maulida, Milati Nurul Muh. Mustakim Muh. Mustakim, Muh. Muhammad Abdurrahman Munir Muhammad Faisal Muhammad Fakhrurrozi Muhyiddin A.M Hayat Munarsih, Dena Nabila , Lathifa Nandy Agustin Syakarofath Nawawi, Bismi Ratu Fortuna Ninisita Sri Hadi Nurinda, Eva Nurwanti, Esti Nuryanti, Sundari Desi Pothitirat, Werayut Pothitirat, Werayut Pratama, Aditya Mandala Pratama, Haka R Pratami, Ria Indah Pratiwi, Sindi Pratiwi, Sindi Prillia, Wiwi Kustio Puspitasari, Ade Rahma Sakti Oktavia Rahmawati, Dewi Astri Ratih Nugraeni ratih ratih Rizal Fauzi Rosa Nikmatul Fajri Rusiyono, Ruwet Rusny Istiqomah Sujono S. Kuba, Muhammad Syafa'at Silvianita, Novi Sri Suprapti Suat, Winda Dheananda Sukma Ananda , RA Dewinta Sulistiari Retnowati Suminingtyas, Ifa Aris Tri Rochmadi Trisna Styawaty Very Ainun Fauziah Vitara, Debby Wahyudi, Andi Wahyuningsih Wahyuningsih Wardani, Astin Eka Wulandari, Ari Susiana Wulandari, Metha Yanhari, Apriza Dwi Yulinda Kurniasari Zahro, Siti