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All Journal Buletin Peternakan SAINS DAN MATEMATIKA Media Kedokteran Hewan Jurnal Sain Peternakan Indonesia Jurnal Ilmu-Ilmu Peternakan (Indonesian Journal of Animal Science) Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Animal Production : Indonesian Journal of Animal Production Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) Communications in Science and Technology Proceeding INTERNATIONAL SEMINAR IMPROVING TROPICAL ANIMAL PRODUCTION FOR FOOD SECURITY Jurnal Medik Veteriner Jurnal Pengabdian Dharma Laksana Jurnal Nutrisi Ternak Tropis dan Ilmu Pakan Molekul: Jurnal Ilmiah Kimia Animal Production
Ali Agus
Faculty of Animal Science, Universitas Gadjah Mada, Yogyakarta
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Engineering Environmental Science Health Professions Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Public Health Veterinary Other

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Journal : Communications in Science and Technology

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Klanceng Honey (Tetragonula laeviceps): Its effect on fasting blood glucose, lipid and hematological profiles, and pancreatic histopathology of diabetic rats Agussalim; Umami, Nafiatul; Nurliyani; Wan Ismail, Wan Iryani; Masyithoh, Dewi; Ustadi; Agus, Ali
Communications in Science and Technology Vol 9 No 2 (2024)
Publisher : Komunitas Ilmuwan dan Profesional Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21924/cst.9.2.2024.1503

Abstract

This study aims to assess the daily ingestion of Klanceng Honey (KH) on fasting blood glucose (FBG), high-density lipoprotein (HDL), total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL), and pancreatic histopathology. Thirty rats were involved and divided into six groups: G1 = untreated normal rats, G2 = untreated diabetic rats (DR), G3 = DR treated with 0.9 mg/kg BW glibenclamide, G4, G5, and G6 = DR treated with 1, 2, and 3 g/kg BW KH, respectively for 28 days. The FBG level of G1 was found lower than that of diabetic rat groups (G2–G6) (p<0.01). The TC level of G1 group on 14th and 28th days was lower than that of G2–G6 groups (p<0.01). The TG levels in all rat groups showed no significant difference at 0–28 days. On 14th day, the LDL level of diabetic groups were higher than the one in G1 group (p<0.01). Meanwhile, on 14th and 28th, the HDL levels of G3–G6 groups, were higher than the one in G1 group (p<0.01). The pancreatic histopathology of all rat groups showed no abnormalities of the Langerhans islets. The daily ingestion of KH prevented FBG, TC, TG, and LDL levels from rising, increased the HDL levels, and protected the pancreatic glands against damage. T. laeviceps honey can potentially be used as a functional food for therapy of DM patients.
Co-Authors Abuzahra, Mutasem Agussalim Agussalim Agussalim, Agussalim Agustine, Restiyana Agustinus Paga Ahmad Romadhoni Surya Putra Aisy, Nadya Durrotul Akhda, Najmu Tsaqib Akintunde, Adeyinka Oye Al Arif, M. Anam Ambar Pertiwiningrum Amin, Muhammad Rijal Masyhur Anam, Moh Sofi'ul Anam, Moh Sofiul Anam, Moh. Sofi'ul Andriyani Astuti Ardista, Rini Arif Nindyo Kisworo Astuti, A Ayuti, Siti Rani Bambang Suwignyo Baskara, Aji Praba BP Widyobroto, BP Brahmantya, Chandra Budi Prasetyo Widyobroto Chusnul Hanim Cuk Tri Noviandi DADIK PANTAYA Daulat Freddy Dennis Poppi Emmy Susanti Erif Maha Nugraha Setyawan FM Suhartati, FM Gunawan Gunawan Hanif, Muhammad Fathin Harper, Karen Herry Agoes Hermadi Hidayah, Kharisma Taufiqa Huda, Thoriqul Irfah Al Ika Sumantri IMAM MUSTOFA Indra Wahyu Pratama, Indra Wahyu Kasmiyati, Kasmiyati Katon, Anas Dien Khairullah, Aswin Rafif khusnul khotimah Kurniawan, Muhammad ‘Ahdi Kustantinah Kustantinah Kusuma, Aditya Putra Lies Mira Yusiati Lilis Hartati LM Yusiati, LM Luis Tavares Masyithoh, Dewi Merry Muspita Dyah Utami Mirni Lamid Muratin, Muratin Nafiatul Umami Noviadi, Cuk Tri Nurliyani Paradhipta, Dimas Hand Vidya Parantoro, Apri Petrus Malo Bulu, Petrus Malo Riza Zainuddin Ahmad Rosyada, Zulfi Nur Amrina Sari, Putri Candrika Siti Andarwati SPS Budhi, SPS Sri Mukodiningsih Subur Priyono Sasmito Budhi Suherni Susilowati Suratman Hadi Priyatno Tridjoko Wisnu Murti Ustadi Wan Ismail, Wan Iryani Wardani, Arrynda Rachma Dyasti Widodo, Hermawan Setyo Yunan Alghifari Yuni Suraningdyah, Yuni