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All Journal JOURNAL OF COASTAL DEVELOPMENT Jurnal Pendidikan dan Pembelajaran Kimia (JPPK) PENA SAINS Edukasi: Jurnal Pendidikan Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Pendidikan Kimia (JPKim) Indonesian Journal of Chemistry EKSAKTA : Jurnal Penelitian dan Pembelajaran MIPA PENDIPA Journal of Science Education JURNAL EDUCATION AND DEVELOPMENT Journal of Education Technology Jurnal Ilmiah Sekolah Dasar Jurnal Pendidikan Fisika dan Teknologi International Journal for Educational and Vocational Studies JCER (Journal of Chemistry Education Research) Jurnal Eduscience (JES) JPPS (Jurnal Penelitian Pendidikan Sains) JPPIPA (Jurnal Penelitian Pendidikan IPA) Jurnal Abdi: Media Pengabdian Kepada Masyarakat Jurnal Penelitian Pendidikan Matematika dan Sains Jurnal Inovasi Pembelajaran Kimia (Journal Of Innovation in Chemistry Education) Studies in Learning and Teaching Jurnal Pendidikan, Sains, Geologi, dan Geofisika (GeoScienceEd Journal) Didaktika: Jurnal Kependidikan Hydrogen: Jurnal Kependidikan Kimia Jurnal Kependidikan: Jurnal Hasil Penelitian dan Kajian Kepustakaan di Bidang Pendidikan, Pengajaran dan Pembelajaran Bioscientist : Jurnal Ilmiah Biologi JIPB (Jurnal Inovasi Pembelajaran Biologi) IJORER : International Journal of Recent Educational Research Jurnal Pengabdian Kepada Masyarakat EduStream: Jurnal Pendidikan Dasar Jurnal Pijar MIPA JSEP (Journal of Science Education and Practice) UNESA Journal of Chemical Education Unesa Journal of Chemistry International Journal of Emerging Research and Review Jurnal Pendidikan MIPA Journal of Current Studies in SDGs Journal of Current Studies in SDGs
Rudiana Agustini
Universitas Negeri Surabaya
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Nursing Physics Public Health Social Sciences Veterinary Other

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Effectiveness of the ICARE-Modification Model in Training Students’ Critical Thinking Skills Rita Makdalena; Rudiana Agustini; Raharjo Raharjo
International Journal of Emerging Research and Review Vol. 4 No. 2 (2026): June
Publisher : IKIP Widya Darma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56707/ijoerar.v4i2.168

Abstract

Objective: Developing students’ critical thinking skills remains a central challenge in higher education, particularly in teacher education programs that demand higher-order cognitive competencies. This study investigates the effectiveness of the ICARE-Modification model—an extended instructional framework integrating Introduction, Connection, Application-modification, Reflection, and Extension stages with AI problem-solving activities—in enhancing undergraduate students’ critical thinking skills. Method:  A quasi-experimental design with a non-equivalent control group was employed involving 60 undergraduate students enrolled in a teacher education program. The experimental group received instruction using the ICARE-Modification model, while the control group experienced conventional lecture-based learning. Data were collected through a validated open-ended critical thinking test assessed using an analytical rubric covering questioning, analysis, evaluation, logical reasoning, and solution formulation. Data were analyzed using independent samples t-tests and Cohen’s d effect size.  Results: The findings suggest that the ICARE-Modification model creates a more interactive and cognitively engaging learning environment that supports the development of students’ critical thinking skills. Through structured stages of learning that involve exploration, discussion, and reflection, students are encouraged to actively construct knowledge and evaluate their own reasoning processes, which ultimately leads to better learning outcomes in critical thinking. Novelty: This study introduces the ICARE-Modification model, an extended instructional framework that integrates the traditional ICARE stages with AI-assisted problem-solving activities to foster students’ critical thinking skills in teacher education. Unlike previous studies that apply ICARE as a conventional instructional model, this research incorporates structured cognitive scaffolding and AI-supported reflective learning to enhance higher-order thinking processes.
Pengembangan Permainan MATCHEL (Matching Chemical Elements) Berbasis Android sebagai Media Pembelajaran Kimia Unsur untuk Meningkatkan Hasil Belajar Peserta Didik Fadia Mu'minatus Solekha; Rudiana Agustini
PendIPA Journal of Science Education Vol 9 No 2 (2025): June
Publisher : UNIB Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/pendipa.9.2.450-457

Abstract

Penelitian ini bertujuan untuk mengetahui kelayakan media permainan MATCHEL berbasis android sebagai media pembelajaran dalam upaya meningkatkan hasil belajar peserta didik pada materi kimia unsur. Kelayakan media ditinjau berdasarkan tiga aspek, yaitu validitas, kepraktisan, dan keefektifan. Instrumen yang digunakan meliputi lembar validasi untuk mengukur validitas, angket respon peserta didik dan lembar observasi aktivitas untuk menilai kepraktisan, serta soal pretest dan posttest untuk mengevaluasi keefektifan. Jenis penelitian yang digunakan adalah Research and Development (R&D) dengan model pengembangan 4D oleh Thiagarajan, namun penelitian dibatasi hingga tahap pengembangan (development). Uji coba dilakukan pada 29 peserta didik kelas XI-Merdeka 1 di SMA IPIEMS Surabaya. Hasil penelitian menunjukkan bahwa media permainan MATCHEL memiliki tingkat validitas isi dan konstruk dengan skor modus masing-masing sebesar 3 dan 4, yang menunjukkan kategori valid. Aspek kepraktisan ditunjukkan melalui persentase angket respon peserta didik sebesar 95,97% dan hasil observasi aktivitas sebesar 91,67%, yang termasuk dalam kategori sangat praktis. Aspek keefektifan dianalisis melalui uji Paired Sample T-Test yang menunjukkan adanya peningkatan hasil belajar setelah penggunaan media, serta persentase ketuntasan klasikal sebesar 89,65%. Dengan demikian, dapat disimpulkan bahwa media permainan MATCHEL berbasis android layak digunakan sebagai media pembelajaran untuk meningkatkan hasil belajar peserta didik pada materi kimia unsur.
Open-Data Serum Metabolomics of Lung Adenocarcinoma for Equitable Early Detection under SDG Target 3.4 Muhammad Nurrohman Sidiq; Rudiana Agustini; Nuniek Herdyastuti; Prima Retno Wikandari; Mirwa Adiprahara Anggarani
Journal of Current Studies in SDGs Vol. 3 No. 4 (2027): December
Publisher : Sekolah Tinggi Agama Islam Sabilul Muttaqin Mojokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63230/jocsis.3.4.325

Abstract

Objective: Sustainable Development Goal (SDG) target 3.4 addresses premature non-communicable disease mortality, yet lung cancer leads cancer mortality among Indonesian men, and low-dose computed tomography screening presumes imaging capacity most low-income settings lack. This study asked which serum pathways are recoverable from open lung adenocarcinoma metabolomics and whether their enzymes are altered in tumor tissue. Method: Serum GC-TOF MS data from the ST000385 ADC2 cohort (43 cases, 43 controls, 152 compounds) were reanalysed in MetaboAnalyst 6.0 using PLS-DA with permutation testing, multivariate ROC, and KEGG enrichment. Enzymes were examined in TCGA-LUAD (483 tumor, 347 normal) with GEPIA2 and survival analysis, and the cohort ST000386 underwent metadata testing. Results: The one-component model separated the groups (R² = 0.492, Q² = 0.302, permutation p < 5 × 10⁻⁴) and reached an AUC of 0.882 on five metabolites, which a sensitivity analysis showed to rest on one correlated axis. Twenty metabolites passed a 5% FDR, and arginine biosynthesis was the most enriched pathway (FDR = 5.8 × 10⁻⁵), whereas the TCA cycle and taurine metabolism did not survive correction. LDHA, PKM and CDO1 predicted survival. ARG1, OTC and CPS1 medians fell in tumor while ASS1 and ARG2 rose modestly. ST000386 carried subject-level metadata that does not associate with its own metabolome. Novelty: The dominant pathway is arginine biosynthesis rather than the Warburg axis of earlier readings, and the enzyme layer shows a dysregulated rather than silenced urea cycle.
Open-Data Serum Metabolomics of Lung Adenocarcinoma for Equitable Early Detection under SDG Target 3.4 Muhammad Nurrohman Sidiq; Rudiana Agustini; Nuniek Herdyastuti; Prima Retno Wikandari; Mirwa Adiprahara Anggarani
Journal of Current Studies in SDGs Vol. 3 No. 4 (2027): December
Publisher : Sekolah Tinggi Agama Islam Sabilul Muttaqin Mojokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63230/jocsis.3.4.325

Abstract

Objective: Sustainable Development Goal (SDG) target 3.4 addresses premature non-communicable disease mortality, yet lung cancer leads cancer mortality among Indonesian men, and low-dose computed tomography screening presumes imaging capacity most low-income settings lack. This study asked which serum pathways are recoverable from open lung adenocarcinoma metabolomics and whether their enzymes are altered in tumor tissue. Method: Serum GC-TOF MS data from the ST000385 ADC2 cohort (43 cases, 43 controls, 152 compounds) were reanalysed in MetaboAnalyst 6.0 using PLS-DA with permutation testing, multivariate ROC, and KEGG enrichment. Enzymes were examined in TCGA-LUAD (483 tumor, 347 normal) with GEPIA2 and survival analysis, and the cohort ST000386 underwent metadata testing. Results: The one-component model separated the groups (R² = 0.492, Q² = 0.302, permutation p < 5 × 10⁻⁴) and reached an AUC of 0.882 on five metabolites, which a sensitivity analysis showed to rest on one correlated axis. Twenty metabolites passed a 5% FDR, and arginine biosynthesis was the most enriched pathway (FDR = 5.8 × 10⁻⁵), whereas the TCA cycle and taurine metabolism did not survive correction. LDHA, PKM and CDO1 predicted survival. ARG1, OTC and CPS1 medians fell in tumor while ASS1 and ARG2 rose modestly. ST000386 carried subject-level metadata that does not associate with its own metabolome. Novelty: The dominant pathway is arginine biosynthesis rather than the Warburg axis of earlier readings, and the enzyme layer shows a dysregulated rather than silenced urea cycle.
Co-Authors Adelia Fitri Syaharani Adyani, Laely Afian, Tilal Afifah, Diah Siti Agustyna Widyaningrum Ahlan Riwahyu Habibi Aida Fikriyah Alberto Yonathan Tangke Allo Andriani, Lupita ANTIKA SARI, VIVIN Arviana Ramadhanti Aryka Khulayda Mardhatilla Asri Susetyo Rukmi Azza Nuriah Widowati BENI SETIAWAN Budi Jatmiko Budi Jatmiko Cahyani, Agis Ayu Dewi Markiah DIAN ERLITA PUTRI, NAZTITI Dian Pradianti Dr. I Nyoman Tika,M.Si . Eka Septianingtyas Elok Sudibyo Ely Rohmawati Ely Rohmawati Endah Rahmawati Erman Erman ERMAN ERMAN Evita Harti Nanda Fadia Mu'minatus Solekha Fatimah, Siti Alihatus Fatimatuz Zahroh Fauziyah Nisyah Feliatra Findiyani Ernawati Asih Firdaus, Laras Fitria Hidayati Fransiska, Yuni Fuaidah, Nur Gea, Natasyah Valencia Nilafah Harun Nasrudin Harun Nasrudin Harun Nasrudin Hasanah, Kholifia Nabila Hasnawati Hasnawati Hasnawati Hasnawati Hendra Eka Nurdyanto Hiatun Sri Wahyuni Hurint, Jansensius Dani I Gusti Agung Komang Diafari Djuni Hartawan I Gusti Ayu Tri Agustiana Ibrahim, Musimin Imran, Yuliana Anggraini Izzatul Muhidah Jansensius Dani Hurint Julianto Julianto Julianto Julianto Julianto Julianto Kuki, Agustina Dua Kusumawati Dwiningsih Laely Adyani Lamdari, Eka Yuniar Retno Laras Firdaus Lathifatul Hikmah Layyina, Nunik Luthfi Faza Afina Riza Walida Luthfi Faza Afina Riza Walida, Luthfi Madlazim Madlazim Madlazim Madlazim Maghfiroh, Lailatul Mahyuddin Syaifulloh Markiah, Dewi Mirwa Adiprahara Anggarani Mirwa Adiprahara Anggarani Muchlis Muchlis Muchlis Muchlis Muchlis Muchlis Muh Makhrus Muhammad Ikhsan Muhammad Nurrohman Sidiq Muhidah, Izzatul Musimin Ibrahim MUSLIMIN IBRAHIM N Narsito NABILAH, SALMA Nafisah, Halimatun Narsito Narsito Narsito Narsito Noera Wahdaniyah Nofi Eriana Sulistiani Nuniek Herdyastuti Nunik Layyina Nur Aida Amyliana NUR ALIZA AGUSTINA, SAVIRA Nur Fuaidah Nur Wakhidah Nurdyanto, Hendra Eka Nurhayati Nurhayati Nurhikma Ramadhana Nurlarasati, Filla Qodaria Oktavilani, Nabila Defti Pradianti, Dian PRATIKNO, PUTRI Prima Retno Wikandari Prima Retno Wikandari PUJI ASTUTIK, SETYO Purwono, Tri Diansy Yana Putra, Armansyah QODARIA NURLARASATI, FILLA Raharjo Raharjo Raharjo Raharjo Raharjo, Raharjo Rika Dyanita Sari Risti Wulaningtyas Rita Makdalena RIZKI, ULFATIKHAH Rizza Danila Rofiqotus Sholeha RR. Ella Evrita Hestiandari Rusly Hidayah Rusmini Rusmini S.Pd. M Kes I Ketut Sudiana . Sari Edi Cahyaningrum Sari, Ilma Indana Satriawan, Muhammad Setiawan, Azzahra Laili Tivalia Putri Shofatun, Anis SHOLIHA, AMILATU Sifak Indana Sigit Purnomo Soda, Fransiska Nay Sri Juari Santoso Sri Juari Santoso Sri Juari Santoso Sri Martini Sri Martini Sri Poedjiastoeti Suhartini, Erna Supardi, ZA Imam Suprayitno Suprayitno Surastri, Surastri Suyatno Suyono Suyono Tangke Allo, Alberto Yonathan TAOFEK, IWAN Tirsa Fitriana Angsari Titik Taufikurohmah Titik Taufikurohmah Tjandrakirana Tjandrakirana Tjipto Prastowo Tjipto Prastowo Toeti Koestiari Toeti Koestiari TOETI KOESTIARI Tukiran Tukiran Tukiran Tukiran Tukiran, Tukiran Utami, Dianita Fitri Utiya Azizah Wahono Widodo Wahono Widodo Wahono Widodo Wahono Widodo Wahyanto, Kharisma Nareswari Wahyuni, Hiatun Sri Wahyuningtyas, Intan Nanda Wasis Wasis Wasis Wasis Wasis Waskito, Rusyariyanto WIDOWATI BUDIJASTUTI Wihdatul Istiqah Yudanti, Yudanti Yuliana Anggraini Imran Yuni Sari Rahayu YUNI SRI RAHAYU Yunita Yunita Yunita Yunita Z. A. Imam Supardi Z. A. Imam Supardi ZA Imam Supardi Zahro, Latifatuz ZAINUL ARIFIN IMAM SUPARDI