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All Journal ACTA VETERINARIA INDONESIANA Jurnal Kedokteran Hewan Jurnal Medika Veterinaria
M Nur Salim
Fakultas Kedokteran Hewan Universitas Syiah Kuala.
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary

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PENGARUH PEMBERIAN EKSTRAK KULIT BATANG JALOH TERHADAP GAMBARAN MIKROSKOPIS GINJAL TIKUS PUTIH (Rattus novergicus) YANG DIINFEKSI (Trypanosoma evansi The Effect of Wilow Bark Ekstract Administration on Microscopic Feature of Male Rats (Rattus novergicus) Kidney Infected with Trypanosoma evansi) Nurdiniyah Nurdiniyah; Nazaruddin Nazaruddin; Sugito Sugito; M Nur Salim; Yudha Fahrimal; Siti Aisyah
Jurnal Medika Veterinaria Vol 9, No 2 (2015): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v9i2.3949

Abstract

The aims of this study was to examine the ability of willow bark extract to prevent kidney tissue damage from T. evansi infection. This study used 25 rats which were randomly divided into 5 treatment groups, each groups consisted of 5 rats. Rats in control group (K0) were not infected with T. evansi and without administration of willow bark extract. Group 1 (P1) was infected with 103/0,3 ml of T. evansi without willow bark extract administration. Group 2, 3, and 4 were infected with 103/0.3 ml T. evansi and received willow bark extract at dose of 30, 45, and 60 mg/kg bw, respectively. Willow bark extract were administered for 3 days consecutively. On day 4, the rats were sacrificed using chloroform and the kidneys were collected for histopathological examination. Data were analyzed descriptively. The results showed that the administration of willow bark extract at doses of 30 and 45 mg/kg bw were able to prevent damage of tubule cells and glomerular renal, while the administration of 60 mg/kg bw resulted in kidney damage, indicated by necrosis in tubular glomerular cells. It could be concluded that willow bark extract at doses of 30 and 45 mg/kg bw were effective to prevent tissue damage in kidneys.Key words: kidneys, willow, Trypanosoma evansi
33. Efficacy of Jatropha(Jatrophacurcas L.) Sap Cream in Inflammation Phase of Wound Healing on Mice Skin Hidayati Hidayati; Muhammad Nur Salim; Ummu Balqis; Dian Masyitha; Cut Dahlia Iskandar; Darmawi Darmawi; Abdul Harris
Jurnal Medika Veterinaria Vol 13, No 2 (2019): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v13i2.14565

Abstract

This study aim to know the efficacy of the jatropha sap cream toward the inflammatory phase of wound healing on the skin of mice. This study used 9 male mice, with 25-40 grams weights and 2-3 months old.  Male mice receiveddivided into 3 groups, and3 deuteronomy.The cut is done in the back as 2 cm long. Wound care is done twice a day at 08.00 am and at 18.00 pm for 3 days. The treatment I (PI) cuts smeared a cream base (as a negatif control); treatment II (PII) smeared 10% jatropha sap cream; and the treatment III (PIII) smeared 0.1% sulfadiazine  (as a positive control).Created a skin sample preparation microtechnic stained with hematoxylin-eosin (HE). The result on the number of infiltration of inflammatory cells and neovascular on PI; PII; and PIII were 402,00 ± 7,21 and 14,00 ± 5,57; 248,67 ± 1,53 and 34,67 ± 7,51; and 343,00 ± 8,89 and 28,00 ± 5,00  (P0,01). Based on the result it be concluded the treatment of 10% jatropha sap cream can speed up the process of the inflammatory phase of wound healing in the skin of mice.
Co-Authors Abdul Harris Amiruddin Amiruddin Andi Novita Aufira Fildza Bahittah Awaluddin Awaluddin Azhari Azhari B. Tri Wibowo Cut Dahlia Iskandar Cut Mentari Fatihah Amran Cut Nila Thasmi Darmawi Darmawi Darmawi Darmawi Dasrul Dasrul Denny Irmawati Dian Masyitha Dwinna Aliza Erdiansyah Rahmi Erina Erina Erwin E Etriwati E Fadli A. Gani Fakhrurrazi Fakhrurrazi Ginta Riady Hennivanda Hennivanda Herialfian Herialfian Hidayati Hidayati Indra Sitorus J Siswanto J Susilo J. Susilo M. Ikhsanuddin M. Isa Morizka Wianda Mudhita Zikkrullah Ritonga Muhammad Hambal Muslim Akmal Nazaruddin N Nazaruddin Nazaruddin Nurdiniyah Nurdiniyah Rezeki Indah Sari Rumi Sahara Zamzami Rusli r Rusli Rusli Rusli Rusli Sari, Wahyu Eka Siti Aisyah Sugito Sugito T. Armansyah T. Fadrial Karmil T. Fadrial Karmil T. Fadrial Karmil T. Zahrial Helmi Teuku Fadrial Karmil Teuku Zahrial Helmi Triva Murtina Lubis Ummu Balqis Wahyuni, Sri Y. Tinasari Yudha Fahrimal Zainuddin Zainuddin