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Journal : Jurnal Medika Veterinaria

Clinical Outcomes of Autologous Serum Eye Drops in Treating Corneal Ulceration in a Domestic Cat: A Case Base Study Eka Putri, Rahmi; Hilmi, Mulkiah; Rahmi, Ulfa; Zamzami, Rumi Sahara; Etriwati, Etriwati; Erwin, Erwin; Sugito, Sugito; Syah, Nada Yulian; Ferdian, Riyan; Sari, Wahyu Eka; Safitri, Jessica Anggun
Jurnal Medika Veterinaria Vol 19, No 2 (2025): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v19i2.46171

Abstract

Corneal ulceration is a frequent ophthalmic disorder in domestic cats that can cause ocular discomfort, visual impairment, and serious complications if left untreated. Conventional medical management often provides limited support for epithelial regeneration, leading to the need for alternative therapeutic options. This case study reports the clinical outcome of using autologous serum eye drops (ASEDs) in the treatment of corneal ulceration in a domestic cat. A cat presented with severe epiphora, conjunctival hyperemia, and a centrally located corneal ulcer confirmed by fluorescein staining. Autologous serum was prepared by weekly collection of 6 mL of blood from the dorsalis antebrachii vein, followed by centrifugation and aliquoting into sterile eye drop bottles stored at 4 C. The serum was applied topically twice daily, accompanied by supportive therapy consisting of vitamin A supplementation, multivitamin injections, and an Elizabethan collar to prevent self-trauma. Clinical scoring (03) was used to monitor epiphora, conjunctival hyperemia, and corneal opacity over the treatment period. Marked improvement was observed within 14 days: epiphora and conjunctival hyperemia resolved completely, while corneal opacity improved from moderate to mild, with fluorescein staining becoming negative, indicating complete epithelial closure. No adverse effects were recorded during therapy. This case highlights the potential of autologous serum eye drops as a safe and effective adjunct treatment for feline corneal ulceration, warranting further investigation in larger cohorts to establish standardized protocols for veterinary ophthalmology
Histopathologic Features of Trachea and Lungs in Chickens with Chronic Respiratory Disease Annisa, Aiza; Darmawi, Darmawi; Etriwati, Etriwati; Balqis, Ummu; Salim, M. Nur; Nazaruddin, Nazaruddin; Aliza, Dwinna; Aisyah, Siti; Awaluddin, Awaluddin; Hasan, Denny Irmawati; Akmal, Muslim; Helmi, T. Zahrial; Asmilia, Nuzul
Jurnal Medika Veterinaria Vol 18, No 1 (2024): J.Med.Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v18i1.37429

Abstract

The purpose of this case study is to determine the changes that exist in chickens infected with Chronic Respiratory disease (CRD). A broiler male chicken aged 40 days was found dead in a chicken basket at Ulee Kareng chicken slaughterhouse in a state of feather loss and feces attached to cloaca, on January 6th, 2023. The chicken was brought to pathology laboratory of Faculty of Veterinary Medicine, Universitas Syiah Kuala for necropsy and organ collection. Organs associated with CRD cases were trachea and lungs and histopathological preparations were carried out, stained with Haematoxylin Eosin, and observed under a microscope. The results of histopathological examination showed hemorrhage and hyperplasia of the tracheal epithelium. Hemorrhage was caused by edema which causes increased vascular permeability and epithelial cell hyperplasia occured due to the body's response to infection or inflammation. In the lungs there was bleeding due to damage to the blood vessel wall which caused increased vascular permeability, so that fluid and blood plasma come out of the blood vessels. Fibrinogen then underwent polymerization which resulted in fibrinous thrombi. Congestion happened as the result of fluid accumulation in a location that occured in a passive process so the fluid failed to escape. Because of the accumulation of fluid (congestion), the blood supply to the lung tissue is interrupted, resulting in several points of necrosis in the lungs.
Newcastle Disease Case in Broiler Chicken Angreini, Meliyantika; Balqis, Ummu; Etriwati, Etriwati; Hasan, Denny Irmawati; Aisyah, Siti; Salim, M. Nur; Nazaruddin, Nazaruddin; Darmawi, Darmawi
Jurnal Medika Veterinaria Vol 17, No 2 (2023): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v17i2.35151

Abstract

Newcastle Disease (ND) is a highly contagious disease with a high mortality rate, infecting poultry, and chickens are very susceptible to ND infection. The purpose of this case report is to find out how to diagnose ND disease in chickens. A 30-day-old white male broiler cadaver obtained from Pasar Lambaro, Aceh Besar was found dead in a holding cage with conjunctival hemorrhage and hair loss. Based on the physical examination of the external condition of the cadaver, it can be seen that the eye membranes are experiencing hemorrhage. There was nasal mucosa hemorrhage and mucous exudate in the nasal cavity. The oral mucosa was also found to have mucous exudate, while the cloaca was bleeding and there was residual green feces. The results of anatomic pathology examination found ptechie in the proventriculus and ventricles, swollen lungs with blackish red color and hemorrhage,with the presence of cheese. There was hemorrhage in other organs including trachea, intestines and tonsils, whilst the brain experienced hyperemia. The spleen was swollen and there were foci of necrosis. Based on the anamnesis, external examination, pathological anatomical examination, and histopathology, the diagnosis of the cause of death of broiler chickens was Newcastle Disease (ND).
Co-Authors . Amiruddin . Erwin . Erwin . Muttaqien . Rusli . Rusli Abdul Harris Abdullah Hamzah Abellisa Abellisa Afif Yuda Kusuma Aminuddin Aminuddin Amiruddin . Amiruddin Amiruddin Amiruddin Amiruddin Anak Agung Gede Sugianthara Angreini, Meliyantika Annisa, Aiza Arman Sayuti Asnita Purnama Awaluddin Awaluddin Azhari Azhari Cut Erika Ramadhana Darmawi . Dasrul Dasrul Dian Masyitha Dirga Rizki Imanda divina dinda hayati Dwinna Aliza Ekowati Handharyani Erina Erina Erwin E Erwin Erwin Erwin Erwin Erwin Erwin Erwin Erwin Evan Kurniawan Faisal Mustafa Ferdian, Riyan Hafifatul Aini Hanif Fadli Hanni Aninaidu Hasan, Denny Irmawati HEFRI YUNALDI Helmi, T. Zahrial Hilmi, Mulkiah Jessica Anggun Safitri Langga Mora Lian Varis Riandi M Daud AK M Hasan M Isa M Jalaluddin M Jalaluddin M Nur Salim M Nur Salim M. Nur Salim Mahdi Abrar Maulina, Siti Raudha Muhammad Isa muhammad isa Muhammad Nur Salim Mulyadi Adam Muslim Akmal Muttaqien M Muttaqien Muttaqien N. Nazaruddin Nazaruddin Nazaruddin Nazaruddin Nazaruddin Novredha Rahmadita Nuzul Asmilia Nuzul Asmilia pani noveliani lubis Rahmi Eka Putri Rahmi, Ulfa Rastina Rastina Razali Daud Rezeki Indah Sari Roslizawaty Roslizawaty Rusli r Rusli r Rusli Rusli Rusli Rusli Rusli Rusli Sari, Wahyu Eka Seftia Yolanda Sitarina Widyarini Siti Aisyah Siti Aisyah Siti Aisyiah Sugito - Sugito Sugito Surachmi Setiyaningsih Syah, Nada Yulian t fadrial karmil T Reza Ferasyi Teuku Fadrial Karmil Teuku Reza Ferasyi Teuku Zahrial Helmi Tri Wahyu Pangestiningsih Ummu Balqis Winaruddin Winaruddin Winaruddin Winaruddin Yula Astuti Zainuddin Zainuddin Zamzami, Rumi Sahara Zuhrawaty Zuhrawaty