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All Journal Vidya Karya Pharmascience Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Medical Laboratory Technology Journal JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) JOPS (Journal Of Pharmacy and Science) Jurnal Kreativitas PKM PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat JURNAL FARMASIMED (JFM) Jurnal Pengabdian Kepada Masyarakat (Mediteg) Jurnal Ilmiah Medicamento Borneo Journal Of Pharmascientech Jurnal Insan Farmasi Indonesia Jurnal Abdi Masyarakat Indonesia Tropical Health and Medical Research Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Safari : Jurnal Pengabdian Masyarakat Indonesia Health Research Journal of Indonesia Jurnal Pengabdian Masyarakat Panacea GEMASSIKA: Jurnal Pengabdian kepada Masyarakat Borneo Journal of Pharmacy Jurnal Pengabdian Farmasi dan Sains
Rahmatullah, Satrio Wibowo
Program Studi Farmasi, Fakultas Matematika Dan Ilmu Pengetahuan Alam, Universitas Lambung Mangkurat
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : JURNAL FARMASIMED (JFM)

 1 
Antimicrobial Activity of Ethanol Extract of Sea Pandan Leaves (Pandanus odorifer) Against Staphylococcus aureus and Escherichia coli Rizki, Muhammad Ikhwan; Sari, Anna Khumaira; Rahma, Salsabila Fadiya; Rahmatullah, Satrio Wibowo; Izma, Hayatun
Jurnal FARMASIMED (JFM) Vol 7 No 1 (2024): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i1.2280

Abstract

Sea pandan (Pandanus odorifer) is used in traditional medicine in India. Sea pandan is efficacious in treating pain, parasites, digestive, liver, and cognitive disorders. Sea pandan is found in coastal areas in South Kalimantan. Sea pandan contains flavonoid compounds that have the potential to be antimicrobials. This study aimed to determine the antimicrobial activity of sea pandan leaf extract. The study began with sample preparation, which included washing the leaves, drying them using an oven, refining the particle size, extracting 70% ethanol, and evaporating the solvent until a thick extract was obtained. Total flavonoid levels in sea pandan leaf extract were determined using the colourimetric method using quercetin standards. Antimicrobial testing was conducted using the diffusion method at concentrations of 30%, 40%, and 50% against Staphylococcus aureus and Escherichia coli. The positive control used was chloramphenicol. The determination of the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) values ??was carried out using the dilution method. The results showed that sea pandan leaf extract contains phenolics, flavonoids, saponins, steroids, and tannins. The total flavonoid content in sea pandan leaf extract is 10.01% w/w equivalent of quercetin. The antimicrobial activity of sea pandan leaf extract against Staphylococcus aureus bacteria is 10.15 - 25.36 mm, while against Escherichia coli in the range of 8.15 - 23.16 mm. Ethanol extract of sea pandan leaves at a concentration of 50% is included in the very strong category in inhibiting Staphylococcus aureus and Escherichia coli. Ethanol extract of sea pandan leaves has an MIC value of 7.5% on Staphylococcus aureus and 15% on Escherichia coli. MBC of sea pandan extract is 15% on Escherichia coli bacteria. This study concludes that the ethanol extract of sea pandan leaves has antimicrobial activity against Staphylococcus aureus (bacteriostatic) and Escherichia coli (bactericidal).
Co-Authors Abdul Hadi Ade Syarif Hakim Adnan Syahrizal Agustina, Ni Kadek Ayu Ahmad Nazar Winarto Akbar, Depy Oktapian Akhmad Junaidi Amali, Dzikra Aulia Angelina Ayu Dela Anisa Desriyanti Anna Humaira Anna Khumaira Sari Apriyanti, Anna Astuti, Karunita Ika Aulia Rahmah Buih, Putri Helena Junjung Dahlia Syahrina Damayanti Rumondang Butar Butar Daniel Wisnugroho Deni Setiawan DENI SETIAWAN Difa Intannia Dyah Anggraeni Dyera Forestryana Dyera Forestryana Eka Fitri Susiani Endah Puwarastuti Endang Kurniasih Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fanli Yudi Anwar Fanli Yudi Anwar Fatimatuz Zahra Fikriyati, Nirmala Fitria Febrianti Gultom, Luis Figo Guntur Kurniawan Hafiz Ramadhan Hafizah, Noor Hayatun Izma Helmina Wati Helsawati Helsawati Hendrya Legenda Herliana Dewi Herningtyas Nautika Lingga Humaidy, Mizan I Dewa Putu Pramantara I Dewa Putu Pramantara I Ketut Adnyana Isnaini, Nazhifah Izma, Hayatun Jenah, Rina Astiyani Khairina Maida Khairunnisa Khalifah, Sefa Nur Khoerul Anwar Khoirunnisa Muslimawati Kurniasari, Winda Tri Liling Triyasmono LINDA WAHYUNI Lisa Andina Lukman Hakim Lukman Hakim Madani, Al Mahendra, Rachul Ridho Mia Fitriana Muhamad Hepriatna Muhammad Ikhwan Rizki Muhammad Reza Fahlevi Muhammad Reza Pahlevi Mulia, Radha Eka Nasya Hafizah Nazhipah Isnani Noor, Riskan Nor Aida Normaidah, Normaidah Novia Novia Nurrahma, Ika Maulida Okta Muthia Sari P.P, Aditya Maulana Pratiwi, Desy Prima Happy Ratnapuri Putra, Aditya Maulana Perdana Putri, Indah Pebriani Qory Rahmat Nazri Rahma, Salsabila Fadiya Rahmayanti Fitriah Ramadhan, Fery Ramadhani , Syahrizal Ratna Restapaty Redanti, Hema Novita Risma Dian Ariyani Rosanti, Diah Aulia Sandi, Dita Ayulia Dwi Saputri, Revita Saragih, Triando Hamonangan Sari , Anna Khumaira Sari, Fitri Novita Sari, Okta Muthia Sari, Sindwi Rinanda Sari, Sri Oktaviani Silviana, Mega Siti Bahzah Siti Nurhaliza Leyla Susiani, Eka Fitri Syifa Auliani Tangkas, Hansel Hens Tjitradi, Sukhito Yohanes Tuti Misrina Wikaningtyas, Pratiwi Yusrinie Wasiaturrahmah