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Efektivitas Ekstrak Daun Kemangi (Ocimum sanctum Linn) Terhadap Mortalitas Larva Aedes aegypti Oktafian Diyas Tamtama; Dita Pratiwi Kusuma Wardani; Muhammad Luthfi Almanfaluthi; Isna Hikmawati
BALABA: JURNAL LITBANG PENGENDALIAN PENYAKIT BERSUMBER BINATANG BANJARNEGARA Volume 18 Nomor 2 Desember 2022
Publisher : Balai Penelitian dan Pengembangan Kesehatan Banjarnegara Badan Litbangkes Kemenkes RI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/blb.v18i2.5414

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Basil leaf (Ocimum sanctum Linn) are known to have the ability as natural larvicides because there are various compounds including tannins, eugenol, flavonoids, essential oils, hexauronic acid, saponins, pentose, xylose, metal homocytic acid, mulludistin, ursolic acid and methyl clavical. This study aims to determine the effectiveness of basil leaf extract (O. sanctum Linn) on mortality of Aedes agypti larvae. This research is a true experimental type with posttest only with control group design. Aedes aegypti larvae obtained from Balitbangkes Banjarnegara were used in this study as many as 450 larvae. This study consisted of 6 groups with 2 control groups (positive control/temefos 1% and negative control/distilled water) and 4 other groups receiving treatment with basil leaf extract concentrations of 1.5%, 1.8%, 2.1%, and 2.4%. Each group contained 25 larvae of Ae. aegypti with three repetitions and observation time with 10th, 40th, 60th, 120th, 240, 720, and 1440 minute intervals. Larval mortality of Ae. aegypti occurred from the 120th minute with a concentration of 2.4% with a mortality percentage of 5.6%. The results of the Kruskal Wallis test showed that there were differences in the mortality of Ae. aegypti at 60, 120, 240, 720, and 1440 minutes. The LC50 value was 2.329% at 720 minutes while the LC90 test was 7.043% at 720 minutes. Basil leaf extract has not been effective as a larvicide because mortality occurred from the 120th minute.
Literature Review: Hubungan Kadar D-Dimer dengan Tingkat Keparahan Pasien Covid-19: Literature Review: The Relationship of D-Dimer Levels with the Sverity of Covid-19 Ismi Andina Pertiwi; Tantri Analisawati Sudarsono; Dita Pratiwi Kusuma Wardani; Minto Rahaju
Jurnal Surya Medika (JSM) Vol. 9 No. 2 (2023): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v9i2.5726

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Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) causes Corona Virus Disease-19 (COVID-19). D-dimer is one of the hemostasis tests performed on patients infected with the disease, it is a product of fibrin degradation and a biomarker of platelet disorders. With the development of COVID-19 as a pandemic, D-dimer has become an indicator for prognosis in COVID-19 patients. Based on symptoms, the severity of COVID-19 patients consists of mild, moderate, and severe symptoms. The author conducted a literature review regarding the correlation between D-dimer levels and the severity of COVID-19 patients. Data and theory were taken from ten references from several databases: Google Scholar, PubMed, Semantic Scholar, Science Direct, Garuda, and Neliti. The references taken were from the 2020-2022 range. In all of these references, statistical test results were obtained with a significant value below 0.05, so it can be concluded that there is a correlation between D-dimer levels and the severity of COVID-19. In COVID-19 infections with severe symptoms, immunothrombosis can occur due to hyperinflammatory conditions and cytokine storms. Immunothrombosis occurs as a result of the body's defense against viral infections. Damage to lung tissue in COVID-19 patients triggers a procoagulant response associated with inflammatory cytokines in blood vessel tissue.
Pengaruh Pemberian Obat Anti Tuberkulosisi (OAT) Terhadap Jumlah Trombosit pada Pasien TB Paru di BKPM Purwokerto: The Effect of Anti Tuberkulosis Drug (OAT) Towards the Number of Pulmonary TB Patients at BKPM Purwokerto Ika Wulan Nuri Anggreani; Tantri Analisawati Sudarsono; Dita Pratiwi Kusuma Wardani; Minto Rahaju
Jurnal Surya Medika (JSM) Vol. 9 No. 2 (2023): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v9i2.5727

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Pulmonary tuberculosis (TB) is an infection of the lungs characterized by pulmonary infiltrates and the formation of caseous granulomas, fibrosis, and cavities. It can be caused by the risk of transmission of the acid-fast bacillus Mycobacterium tuberculosis. One supportive treatment for pulmonary TB is the administration of anti-tuberculosis drugs (OAT). The content of rifampicin in the anti-tuberculosis drug can cause side effects of hemorrhagic disorders, namely thrombocytopenia. This study aims to determine the effect of giving OAT on platelet counts in TB patients in treatment phases of 0, 2, and 6 months at BKPM Purwokerto (Balai Kesehatan Paru Masyarakat). This was a type of analytic observational study with a cross-sectional design. Patients with pulmonary TB in treatment phase 0 were 15 at two months and 15 at six months in this study. Sampling was carried out by purposive sampling with inclusion and exclusion criteria. From this analysis, it is known that the data used the one-way ANOVA test. The results obtained have a p-value of 0.101 (p 0.05), so it can be concluded that there is no effect of the administration of OAT on platelet counts in TB patients in the treatment phases of 0, 2, and 6 months.
Risk Factors of Typhoid Fever in Adolescents in PKU Muhammadiyah Singkil Islamic Hospital, Tegal District Wardani, Dita Pratiwi Kusuma
TEKNOLOGI MEDIS DAN JURNAL KESEHATAN UMUM Vol 8 No 1 (2024): Medical Technology and Public Health Journal March 2024
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mtphj.v8i1.4942

Abstract

Typhoid fever is an acute infectious disease of the small intestine caused by the bacteria Salmonella typhi or Salmonella paratyphi A, B, and C. Various factors influence the occurrence of typhoid fever, including handwashing habits, consuming snacks outside the home, and environmental conditions around the house. This study aims to determine the risk factors for the incidence of typhoid fever in adolescents at PKU Muhammadiyah Singkil Hospital, Tegal Regency. The research employed an analytical observation with a cross-sectional design conducted from April to June 2021. The research method included the Widal test and filling out questionnaires.  Data were analyzed using univariate and chi-square tests. The results of this study revealed 14 positive patients with typhoid fever, with a Widal titer of 1/160 (40%) and a Widal titer of 1/320 in 21 people (60%). There was no significant relationship between the habit of handwashing and the incidence of typhoid fever (p = 0,076). Similarly, no significant relationship was found between the habit of eating outside the home and the incidence of typhoid fever (p = 0,144). However, a significant relationship was observed between environmental conditions around the house and the incidence of typhoid fever (p = 0,009). It is recommended that individuals improve personal hygiene and the environment around their homes to reduce Salmonella typhi infection.  Keywords: Salmonella typhi, typhoid fever, widal test
The Role of Environmental Sanitation and Personal Hygiene in Soil Transmitted Helminths Infection in School-Age Children in Banjarharjo Sub-district EKANIASARI, MEVIANA DEA; WARDANI, DITA PRATIWI KUSUMA; MUJAHID, IKHSAN; ALMANFALUTHI, MUHAMMAD LUTHFI
TEKNOLOGI MEDIS DAN JURNAL KESEHATAN UMUM Vol 8 No 2 (2024): Medical Technology and Public Health Journal September 2024
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mtphj.v8i2.5549

Abstract

Helminthiasis in school-age children can impede both physical and cognitive development. Poor personal hygiene practices are associated with various health issues among schoolchildren, including diarrhoea and helminth infections. A healthy environment is crucial for physical and mental well-being, whereas poor sanitation significantly increases the risk of infectious diseases. This study aims to examine the relationship between environmental sanitation, personal hygiene, and soil-transmitted helminth infections among school-age children in the Banjarharjo Sub-district. This analytic observational study employed a cross-sectional design and was conducted in July 2023. Data collection involved administering a personal hygiene and environmental sanitation questionnaire, alongside identifying soil-transmitted helminth (STH) eggs in faeces and nail samples using the MgSO4 sedimentation method. Participants were selected through purposive sampling based on predefined inclusion and exclusion criteria. The study population comprised school-age children from Banjarharjo District, with a final sample size of 58 children from Sindangheula Village and Cikuya Village. Data analysis was performed using the Fisher exact test. The results showed no association between environmental sanitation (faeces p = 0.583; nails p = 1.00) and personal hygiene (faeces p = 1.00; nails p = 1.00) and soil-transmitted helminth infection in both faeces and nail samples (p > 0.05). Therefore, the study found no significant relationship between environmental sanitation, personal hygiene, and soil-transmitted helminth infection among school-age children in Banjarharjo Sub-district.  Keywords: Environmental sanitation, personal hygiene, school age, soil-transmitted helminths
The Role of Body Mass Index, Hemogblobin Levels in Women Giving Birth to Neonatal Weight Tantowi, Linda Yanuana Fanida; Wardani, Dita Pratiwi Kusuma; Kurniawan; Ambarwati, Dewi
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 17 No 1 (2023): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v17i1.5774

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Maternal nutritional status is monitored with BMI and is also one of the factors that have an impact during pregnancy. Poor nutrition before and during pregnancy leads to decreasing hemoglobin levels and low birth weight infants. This study aims to determine the correlation between hemoglobin levels and BMI of mothers giving birth to the weight of newborns at the Puskesmas Kebumen II, Kebumen District. This research used a retrospective study with medical record data collected from January to April 2022. This research involved 50 patient mothers giving birth at Puskesmas Kebumen II, Kebumen District. The data were analyzed by the Pearson correlation coefficient test. The results are BMI and newborn weight (p = 0.061, r = 0.367), hemoglobin levels, and newborn weight (p=0.852; r= -0.025). There was no correlation between BMI and hemoglobin levels to newborn weight at Puskemas Kebumen II, Kebumen District.
Determination Of IgE Levels In Allergies Among Medical Laboratory Technology Students In Universitas Muhammadiyah Purwokerto SUDARSONO, TANTRI ANALISAWATI; KUSUMA WARDANI, DITA PRATIWI; MULYANTO, ARIF
Pena Medika Jurnal Kesehatan Vol 11, No 1 (2021): PENA MEDIKA JURNAL KESEHATAN
Publisher : Universitas Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31941/pmjk.v11i1.1259

Abstract

The prevalence of allergies is increasing from year to year due to the modern lifestyle in society. The incidence of allergies was influenced by several factors, such as genetics, age, sex, diet, food type, and also environmental factors. Determination Ig E levels in adolescents and young adults is important because the incidence of allergy is highly reported in adolescents and young adults. This study was conducted to determine Ig E levels in allergies among university students in Universitas Muhammadiyah Purwokerto This observational study was conducted among diploma students of Medical Laboratory Technology, Universitas Muhammadiyah Purwokerto. The data of characteristic subjects were collected by a self-administered questionnaire whereas data of Ig E levels were collected by serum samples and measured by ELISA. A total of 23 students (4,35 % male and 95,65% female) were included. Seafood allergy (25%) were the commonest allergy among the students. Only 9% of subjects have combination allergies. The highest of Ig E levels were 365 IU/mL.
Identification of Intestinal Parasites in Spinach at Padamara Market, Padamara District JANG JAYA, NABELA PUTRI; WARDANI, DITA PRATIWI KUSUMA; MUJAHID, IKHSAN; ALMANFALUTHI, MUHAMMAD LUTHFI
Jurnal Medis Islam Internasional Vol 6 No 1 (2024): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v6i1.5531

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Introduction: Vegetables are essential for maintaining human health because they are a great source of vitamins, minerals, fiber, and other nutrients. Most people consume raw vegetables to preserve the nutrients in them. However, raw vegetables have a great potential to spread intestinal parasitic infections. Raw vegetables consumed as fresh vegetables also have the potential to transmit geohelminth infection. Protozoan infections can be transmitted through food and some of these diseases. Objective: This study aims to identify intestinal parasites in spinach at Padamara Market, Padamara District Methods: A total sampling technique was used to collect 20 bunches of spinach at Padamara Market, Padamara District, and the identification of intestinal parasites using the 0.2% NaOH sedimentation method was carried out at the Laboratory of Microbiology and Parasitology, Faculty of Medicine, Universitas Muhammadiyah Purwokerto in April–May 2021. Results: 14 samples (70%) of spinach were positive for intestinal parasites, while 6 samples (30%) were negative for intestinal parasites. The results of intestinal parasite identification found the presence of Ascaris lumbricoides eggs as many as 10 (30.3%), Minute Intestinal Fluke eggs as many as 6 (18.18%), and Entamoeba coli cysts as many as 17 (51.52%). Conclusions: A. lumbricoides egg, Minute Intestinal Fluke eggs, and E. coli cyst were identified in spinach at Padamara Market, Padamara District
Hubungan Aktivitas Fisik Dengan Kadar Rheumatoid Factor Pada Lansia Dita Pratiwi Kusuma Wardani; Syifa Arrachmah; Retno Sulistiyowati; Minto Rahaju
Jurnal Kesehatan Vol. 17 No. 1 (2024): Jurnal Kesehatan
Publisher : UPPM Poltekkes Kemenkes Ternate

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32763/z153zc45

Abstract

Latar Belakang: Rheumatoid Arthritis (RA) tergolong penyakit sistemik yang cenderung menjadi kronis dan sering menyerang sendi. Usia menjadi salah satu fakto risiko terjadinya RA. Rheumatoid Factor (RF) merupakan immunoglobulin yang bereaksi dengan molekul IgG, pada serum penderita juga mengandung IgG. RF merupakan parameter atau pemeriksaan yang digunakan untuk mendeteksi adanya RA. Tujuan: Tujuan penelitian ini untuk mengetahui hubungan antara aktivitas fisik dengan kadar rheumatoid factor pada lansia. Metode: Penelitian ini menggunakan rancangan cross sectional dengan melibatkan 28 orang lansia di Desa Banteran, Kecamatan Wangon, Kabupaten Banyumas pada bulan Mei-Juni 2023. Responden dilakukan pemeriksaan kadar RF dengan metode aglutinasi lateks dan pengisian kuesioner IPAQ yang telah dimodifikasi untuk menentukan aktivitas fisik. Data dianalisis dengan Fisher Exact (X2). Hasil: Hasil analisis Fisher Exact terdapat hubungan signifikan antara aktivitas fisik dengan kadar RF (p= 0,001; OR= 2.5; CI 95%= 1.346-4.646). Tidak terdapat lansia dengan aktivitas fisik sedang yang memiliki kadar RF reaktif sedangkan lansia dengan aktivitas fisik sedang yang memiliki kadar RF non reaktif sebanyak 13 orang (100%). Lansia dengan aktivitas fisik berat yang memiliki kadar RF reaktif sebanyak 9 orang (60%) sedangkan lansia dengan aktivitas fisik berat yang memiliki kadar RF non reaktif sebanyak 6 orang (40%). Lansia dengan aktivitas fisik berat berisiko 2.5 untuk memiliki kadar RF reaktif. Kesimpulan: Terdapat hubungan signifikan antara aktivitas fisik dengan kadar RF lansia. Responden dengan aktivitas fisik berat memiliki peluang 2,5 kali untuk memiliki kadar RF reaktif.
PERBANDINGAN EFEKTIVITAS EKSTRAK BAWANG PUTIH DAN DAUN MENGKUDU SEBAGAI BIOLARVASIDA TERHADAP LARVA NYAMUK Aedes aegypti Chaeni, Annisa Nur; Mujahid, Ikhsan; Wardani, Dita Pratiwi Kusuma; Almanfaluthi, Muhammad Lutfhi
Jurnal Kesehatan Vol 15, No 1 (2024)
Publisher : Sekolah Tinggi Ilmu Kesehatan (STIKes) Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38165/jk.v15i1.424

Abstract

Pengendalian nyamuk Aedes aegypti dengan menggunakan bahan kimia memiliki dampak negatif terhadap lingkungan dan kesehatan maupun organisme hidup. Upaya yang dapat dilakukan untuk meminimalisir dampak negatif yang ditimbulkan maka digunakan lavarsida alami dari tanaman yang memiliki potensi untuk membunuh Aedes aegpyti pada stadium larva. Penelitian ini bertujuan mengetahui efektivitas ekstrak bawang putih dan daun mengkudu sebagai biolarvasida terhadap mortalitas larva nyamuk Ae. aegypti. Penelitian ini merupakan penelitian true experimental dengan desain post test only with control group design. Sampel pada penelitian ini sebanyak 825 ekor. Teknik pengambilan sampel dilakukan dengan metode random sampling. Kelompok penelitian ini adalah temefos 1% dan aquadest, kelompok perlakuan ekstrak bawang putih (A. sativum) dan daun mengkudu (M. citrifolia) dengan masing – masing konsentrasi 0,2%, 0,4% dan 1%. Analisis data menggunakan uji Friedman, dilanjutkan dengan uji Post Hoc Mann-Whitney U dan analisis probit dilakukan untuk mengetahui nilai LC50 dan LC90. Setelah dilakukan olah data hasil penelitian menunjukan bahwa yang efektif dalam mortalitas larva 56% dan 30.4% dalam waktu 120 menit. Teirdapat peirbandingan antara eikstrak bawang puitih dan dauin meingkuidui seibagai biolarvasida teirhadap larva nyamuik Aei. aeigypti pada waktui peingamatan 120 meinit pada eikstrak bawang puitih yaitui 56% deingan meidian 14,00 (13-15) dan eikstrak dauin meingkuidui meincapai 30,4% deingan meidian 8,00 (7-8) seidangkan kombinasi eikstrak bawang puitih dan dauin meingkuidui yaitui 36% deingan meidian 9,00 (8-10), nilai LC50 dan LC90 ekstrak bawang putih adalah 0.135% dan 1.033% sedangkan nilai LC50 dan LC90 ekstrak daun mengkudu adalah 0.081% dan 1.621%. Bagi peneliti selanjutnya peirlui dilakuikan uiji kombinasi keiduianya deingan konseintrasi yang leibih tinggi dan seibaiknya dilakuikan uiji LT (Leithal Timei) sebagai larvasida alami yang ramah lingkungan.Kata Kunci: A. aegypti; Bawang Putih; Biolarvasida; Daun MengkuduAbstractControlling Aedes aegypti mosquitoes using chemical substances can have negative impacts on the environment, health, and other living organisms. To minimize these negative effects, natural larvicides derived from plants with the potential to kill Aedes aegypti larvae are utilized. This research aims to determine the effectiveness of garlic extract and noni leaves as bio-larvicides against the mortality of Aedes aegypti mosquito larvae. This true experimental research used a post-test-only control group design. The sample size was 825 larvae, selected through random sampling. The research groups included a temephos 1% and aquadest control group, a garlic extract (A. sativum) treatment group with concentrations of 0.2%, 0.4%, and 1%, and a noni leaves (M. citrifolia) treatment group with the same concentrations. Data analysis involved the Friedman test, followed by the Mann-Whitney U post-hoc test, and probit analysis to determine LC50 and LC90 values. The results show that the most effective treatment resulted in a larval mortality of 56% and 30.4% within 120 minutes. The LC50 and LC90 values for garlic extract are 0.135% and 1.033%, respectively, while for noni leaves, they are 0.081% and 1.621%. Future research is expected to further explore the potential of garlic and noni leaves as environmentally friendly natural larvicides.Keywords: A. aegypti; Garlic; Biolarvicides; Noni Leaves
Co-Authors Almanfaluthi, Muhammad Lutfhi Amalia Ovi Mustika Seno Ambarwati, Dewi Annisa Nur Chaeni Aprianto . Arif Mulyanto Arif Mulyanto Arif Mulyanto, Arif Atika Nur Azizah ATIKA NUR AZIZAH Cahyaningrum, Winda Rahma Chaeni, Annisa Nur Dewi Kristiya Nugra Heny Dhanti, Kurnia Ritma Dhanti, Kurnia Ritma Dina Aristya Purdiani EKANIASARI, MEVIANA DEA Farida Dwi Handayani Firman Jaelani HAMNA FATHIA ZAHRA Handayani Narendo Putri handayani, Farida Heny, Dewi Kristiya Nugra Ika Wulan Nuri Anggreani Ikhsan Mujahid Ikhsan Mujahid Ikhsan Mujahid IKHSAN MUJAHID Indah Mulyani Ismi Andina Pertiwi Isna Hikmawati Isna Hikmawati ISNA HIKMAWATI Janatin Nur Aripin JANG JAYA, NABELA PUTRI Ketut Tirtayasa Kurnia Ritma Dhanti Kurniawan Kurniawan Kurniawan Linda Wijayanti Listiyowati, Tanti M Luthfi Almanfaluthi M. Luthfi Almanfaluthi Mika'il, Hikam Minto Rahaju Minto Rahaju Muhammad Lutfhi Almanfaluthi Muhammad Luthfi Muhammad Luthfi Almanfaluthi Muhammad Luthfi Almanfaluthi Muhammad Luthfi Almanfaluthi Muhammad Luthfi Almanfaluthi MUJIONO, TIMBUL Nadia Ega Haliza Nuri Anggreani, Ika Wulan Nurul Badriyah Nurul Badriyah Nurul Qomariyah Oei Stefani Yuanita Widodo OEI STEFANI YUANITA WIDODO Oktafian Diyas Tamtama Olivia Alfitri Qo'imah, Alamanda Nurul Qo’imah, Alamanda Nurul Rahaju, Minto RETNO SULISTIYOWATI Retno Sulistiyowati RETNO SULISTYOWATI Retno Sulistyowati Retno Sulistyowati Ristiyanto Ristiyanto Ristiyanto ROHMAH, JAZILATUR Santi Safitri Shely Ayu Lestari SUDARSONO, TANTRI ANALISAWATI Sudarsono, Tantri Analisawati Supriyadi Supriyadi Supriyadi Syafira Dian Ergiana Syifa Arrachmah Tantowi, Linda Yanuana Fanida Tantri Analisawati Sudarsono Tantri Analisawati Sudarsono Tantri Analisawati Sudarsono Tantri Analisawati Sudarsono Wijayanti, Linda Yunita Nurmalasari