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Correlation Between HbA1C Levels And C-Reactive Protein Levels In Diabetes Mellitus Patients MUJIONO, TIMBUL; WARDANI, DITA PRATIWI KUSUMA; MULYANTO, ARIF; RAHAJU, MINTO
Jurnal Ilmiah Kesehatan Vol 18 No 01 (2025): Jurnal Ilmiah Kesehatan (Journal of Health Science) 
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/jhs.v18i01.5922

Abstract

Diabetes mellitus (DM) is a chronic disease characterised by elevated blood glucose levels ≥ 200 mg/dl due to metabolic disorders. Insulin resistance triggers a blood glucose imbalance, resulting in no energy supply needed by the body's cells. The condition of DM is destructive to the body and, therefore, needs to be measured with stable parameters for the long term. HbA1c is a standard clinical examination used as a determinant of glycaemic status in DM disease. C-reactive protein (CRP) level is an effective parameter in determining the index of damage or inflammation that occurs in the body due to DM. This study aims to determine the relationship between HbA1c levels and CRP levels in patients with diabetes mellitus at Dr. Sardjito Hospital. Twenty patients with type 2 diabetes mellitus were included in this study using the purposive sampling technique. HbA1c data and CRP levels were analysed with the Spearman correlation test. The Pearson correlation test results showed a p-value = 0.001 and an r-value = 0.705. There is a relationship between HbA1c levels and CRP levels in DM patients at RSUD Dr. Soedirman Kebumen.
Diversity of Mites in Captured Rats and the Role of Rickettsiosis in Semarang City and Demak Regency Mulyani, Indah; Ristiyanto; ALMANFALUTHI, MUHAMMAD LUTHFI; Handayani, Farida; WARDANI, DITA PRATIWI KUSUMA
Acta VETERINARIA Indonesiana Vol. 13 No. 1 (2025): Maret 2025
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avi.13.1.77-86

Abstract

Ricketssiosis ditularkan oleh tikus baik secara kontak langsung maupun gigitan ektoparasit. Ektoparasit merupakan parasit vector penularan penyakit rickettsia yang hidupnya pada permukaan tubuh atau di bagian luar inangnya. Ektoparasit yang sering ditemukan di tikus salah satunya tungau. Penelitian ini bertujuan untuk mengetahui indeks ekologi ektoparasit tungau pada tikus yang tertangkap di Kota Semarang dan Kabupaten Demak pada bulan Juni – Agustus 2023. Penelitian ini adalah observasional deskriptif dengan metode yang digunakan survey rodent dengan teknik yaitu teknik accidental sampling. Jumlah tikus yang tertangkap sebanyak 218 ekor dengan jenis Rattus Norvegicus, Rattus Norvegicus javanus, Rattus Tanezumi, Rattus Argentiventer, Suncus Murinus, Mus Musculus. Hasil spesies tungau yang ditemukan yaitu Laelaps nutalli, Laelaps turkestanicus, Eulaelaps stabularis, Echinolaelaps echidninus, Dermanyssus gallinae, Ornithonyssus bacoti dengan total 2.116 individu. Rata-rata nilai indeks keanekaragaman adalah 1,00 (Semarang) dan 0,78 (Demak) termasuk kategori sedang dan tinggi. Banyaknya tikus yang tertangkap dan banyaknya tungau memengaruhi kesehatan lingkungan, terutama manusia. Kelimpahan tungau Laelaps nutalli perlu diwaspadai karena sebagai salah satu yang berpeluang menularkan murine typhus.
Comparison of TSH Levels Pulmonary Tuberculosis Patients at The Phase 0 and 6 Months Treatment Qo'imah, Alamanda Nurul; Wardani, Dita Pratiwi Kusuma; Sudarsono, Tantri Analisawati; Mulyanto, Arif
jitek Vol 10 No 1 (2022): September 2022
Publisher : Poltekkes Kemenkes Jakarta III

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32668/jitek.v10i1.910

Abstract

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. Pulmonary TB has become a health problem worldwide, including in Indonesia, because the sufferers' prevalence is increasing every year. The increase in TB drug resistance will pose a severe health threat. The continuous consumption of drugs in large quantities and high doses can affect the function of the thyroid gland. This study aimed to determine the levels of thyroid stimulating hormone (TSH) in pulmonary tuberculosis patients with treatment phases of 0 months and six months. This research is analytical observational research with a cross-sectional research design. The sampling method uses accidental sampling. A total of 42 respondents participated in this study to determine the levels of TSH in pulmonary TB. The results of the Mann-Whitney U test showed no difference in TSH levels in pulmonary TB patients with different treatment phases of 0 months and six months (p = 0.3). There was no significant difference between TSH levels in pulmonary TB patients in the 0 and 6-month treatment phases.
Comparison of Ureum and Creatinine Levels Pulmonary Tuberculosis in Phase 0 and 6 Moths Treatment Aprianto, Aprianto; Sudarsono, Tantri Analisawati; Kusuma Wardani, Dita Pratiwi; Rahaju, Minto
jitek Vol 10 No 1 (2022): September 2022
Publisher : Poltekkes Kemenkes Jakarta III

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32668/jitek.v10i1.927

Abstract

Pulmonary tuberculosis is a disease caused by Mycobacterium tuberculosis. Treatment for tuberculosis patients is given in the intensive and advanced stages. Anti-tuberculosis drugs can be nephrotoxic to cells in the kidneys. This research is an analytic observational study to know the comparison of urea and creatinine levels in pulmonary tuberculosis patients in the 0 and 6-month treatment phases at the Community Lung Health Center Purwokerto. The samples studied were 42 respondents who were taken by accidental sampling. This study was conducted from December 2021 to January 2022. Out of the 42 pulmonary tuberculosis patients who received treatment at 0 and 6 months, the majority of pulmonary tuberculosis patients were 28 patients (66.7%) had normal urea levels, and 38 patients (90.5 %) had normal creatinine levels. Urea levels in pulmonary tuberculosis patients during the 0-month treatment phase were 9 (2-24) mg/dL, while in the 6-month treatment phase, it was 8 (1-37) mg/dL. The creatinine level of pulmonary tuberculosis patients with 0-month treatment phase was 0.98 (0.64-1.62) mg/dL, while in the 6-month treatment phase it was 0.88 (0.62-1.92) mg/dL. There was no significant comparison of urea and creatinine levels in pulmonary tuberculosis patients with treatment phases 0 and 6 months (p>0.05).
Relationship Between Results of Genexpert RT-PCR and Erythrocyte Sedimentation Rate in Suspected Tuberculosis Patients Listiyowati, Tanti; Wardani, Dita Pratiwi Kusuma; Sudarsono, Tantri Analisawati; Wijayanti, Linda
jitek Vol 10 No 2 (2023): Maret 2023
Publisher : Poltekkes Kemenkes Jakarta III

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32668/jitek.v10i2.1078

Abstract

Pulmonary tuberculosis (TB) is an infectious disease that attacks the lungs and is caused by the bacterium Mycobacterium tuberculosis. The GeneXpert RT-PCR examination (Xpert MTB / RIF) is a development of a diagnostic tool that can automatically detect the presence of Mycobacterium tuberculosis (MTB) by molecular examination and can be used to detect MTB resistance to rifampicin. Erythrocyte sedimentation rate (ESR) is a test used to determine the rate at which erythrocytes settle in the blood. The purpose of this study was to determine the relationship between GeneXpert RT-PCR results and ESR in suspected tuberculosis patients. This research uses a cross-sectional study. The sample used in this study were 56 new suspected TB patients who had never been treated for ATD and underwent GeneXpert RT-PCR examination. Sampling was carried out by purposive sampling with the TCM Rif Sen group and negative results. A total of 27 patients (96.4%) with Rif Sen's GeneXpert RT-PCR results had high ESR values. 15 patients (53.6%) with negative GeneXpert RT-PCR results had normal ESR values. The results of the Chi Square test (X2) show that p-value = 0.000 OR = 0.032. There is a significant relationship between GeneXpert and ESR values ​​in suspected tuberculosis
Analisi Kandungan Timbal (Pb) Pada Air Sumur Di Sekitar Tempat Pembuangan Akhir Kalipancur Kabupaten Purbalingga Heny, Dewi Kristiya Nugra; Dhanti, Kurnia Ritma; Wardani, Dita Pratiwi Kusuma
Jurnal Analis Medika Biosains (JAMBS) Vol 9, No 1 (2022): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v9i1.224

Abstract

Air memiliki peran penting dalam memenuhi kebutuhan manusia sebagai sumber air minum. Salah satu penyebab pencemaran air adalah logam berat. Tujuan penelitian ini adalah menganalisis kandungan timbal (Pb) pada air sumur di sekitar TPA Kalipancur Kabupaten Purbalingga. Penelitian ini dilakukan secara observasional deskriptif pada bulan Agustus 2020 di Laboratorium Kimia Analisis dan Biologi Farmasi Fakultas Farmasi Universitas Muhammadiyah Purwokerto. Teknik pengambilan sampel dilakukan secara purposive sampling. Sebanyak 10 sampel air sumur diambil dengan radius 100-500 m dari TPA Kalipancur. Kadar timbal (Pb) diukur menggunakan metode Atomic Absorption Spectrophotometer (AAS) dan dianalisis secara deskriptif numerik. Hasil penelitian menunjukkan kandungan timbal (Pb) pada seluruh sampel air sumur di sekitar TPA Kalipancur Kabupaten Purbalingga sebesar <0,01 mg/L. 
Perbedaan Hasil Pemeriksaan Widal Metode Slide menggunakan Sampel Serum dan Plasma EDTA pada Mahasiswa Teknologi Laboratorium Medik Badriyah, Nurul; Mulyanto, Arif; Wardani, Dita Pratiwi Kusuma; Sulistyowati, Retno
Jurnal Analis Medika Biosains (JAMBS) Vol 9, No 2 (2022): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v9i2.283

Abstract

Demam tifoid merupakan penyakit infeksi akut usus halus yang disebabkan oleh bakteri S. typhi dan S. paratyphi. Penyakit demam tifoid termasuk penyakit menular. Penularan disebabkan karena makanan atau minuman yang disajikan tidak bersih dan tingkat higenis individu sanitasi lingkungan. Pemeriksaan widal merupakan suatu pemeriksaan serologis untuk mendeteksi antibodi terhadap bakteri S. typhi yang berdasarkan reaksi aglutinasi antara antigen dengan antibodi yang disebut aglutinin, dengan mengukur aglutinasi titer antibodi terhadap antigen O dan H dalam sampel. Penelitian ini bertujuan untuk mengetahui ada tidaknya perbedaan nilai titer pada pemeriksaan widal yaitu metode slide sampel serum dan plasma EDTA dengan rancangan cros sectional sampel yang digunakan sebanyak 26. Pada Mahasiswa Teknologi Laboratorium Medik. Data yang dihasilkan dianalisis dengan uji univariat dan uji pearson chi square. Hasil penelitian ini didapatkan hasil pada serum terbanyak yaitu pada titer 1/320 (61,5%) sedangkan pada plasma EDTA terbanyak yaitu pada titer 1/80 (46,2%) yang menunjukan nilai p velue 0,0247 (p >0,05), maka berdasarkan hasil tersebut dapat disimpulkan bahwa tidak terdapat perbedaan antara pemeriksaan widal menggunakan sampel serum dan plasma EDTA antigen O dan H.       
Hemoglobin Levels in Pregnant Women: A Cross-Sectional Study at Puskesmas Purwokerto Timur II, Indonesia ROHMAH, JAZILATUR; WARDANI, DITA PRATIWI KUSUMA; AMBARWATI, DEWI; SUDARSONO, TANTRI ANALISAWATI
Jurnal Medis Islam Internasional Vol 7 No 1 (2025): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v7i1.6978

Abstract

Introduction: Hemoglobin is a crucial protein in red blood cells responsible for transporting oxygen and carbon dioxide throughout the body. According to the World Health Organization (WHO), an estimated 41.8% of pregnant women worldwide experienced iron deficiency anemia in 2012. In Indonesia, the prevalence of anemia among pregnant women remains high at 37.1%, with Banyumas District reporting an even higher rate of 50.7% in 2016. Objective: This study aimed to assess hemoglobin levels in pregnant women attending the Puskesmas Purwokerto Timur II, Banyumas District. Methods: A descriptive observational study with a cross-sectional design was conducted from April to May 2021. Data collection included respondent identity and medical history through questionnaires, while hemoglobin (Hb) levels were measured using the Azidemet method with the POCT (Point of Care Testing) device. A purposive sampling technique was employed, enrolling 20 respondents. Results: The results showed that 95% (19 out of 20) of the participants had normal hemoglobin levels. The mean Hb levels were 13.929 ± 0.6047 mg/dL in the first trimester, 11.500 ± 1.7804 mg/dL in the second trimester, and 13.067 ± 0.8501 mg/dL in the third trimester. Conclusions: Overall, none of the pregnant women included in the study were diagnosed with anemia.
Kadar Thyroid Stimulating Hormones (TSH) dan Kadar Ureum Pada Penderita Tuberkulosis Paru Wardani, Dita Pratiwi Kusuma; Sudarsono, Tantri Analisawati; Aprianto, Aprianto; Qo’imah, Alamanda Nurul
The Indonesian Journal of Infectious Diseases Vol. 9 No. 2 (2023): The Indonesian Journal of Infectious Disease
Publisher : Rumah Sakit Penyakit Infeksi Prof Dr. Sulianti Saroso

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32667/ijid.v9i2.163

Abstract

Latar belakang: Tuberkulosis (TBC) termasuk dalam sepuluh penyakit teratas yang menyebabkan kematian. Pemberian obat anti tuberkulosis (OAT) bertujuan untuk memberikan pengobatan dan memastikan bahwa pasien mendapat dukungan dan perawatan yang memadai. Pemberian OAT juga diketahui memiliki efek samping seperti disfungsi hati, disfungsi ginjal, neuropati perifer, arthromyalgia, ruam kulit, disfungsi vestibular. Tujuan: mengetahui hubungan kadar Thyroid Stimulating Hormones (TSH) dan kadar ureum pada penderita tuberkulosis paru. Metode: Penelitian berjenis cross-sectional dan sampel sebanyak 42 orang pasien TB paru dengan fase pengobatan 0 dan 6 bulan di BKPM Purwokerto. Data dianalisis dengan korelasi Spearman. Hasil: Rerata kadar TSH pasien TB paru dengan fase pengobatan 0 bulan adalah 2.219 ± 0.810 µIU/mL. Sebanyak 20 orang pasien (95.24%) memiliki kadar TSH normal dan 1 orang pasien (4,76%) memiliki kadar TSH tidak normal. Rerata kadar ureum pasien TB paru dengan fase pengobatan 0 bulan adalah 9.905 ± 5.907 mg/dL. Tidak terdapat korelasi antara kadar TSH dengan kadar ureum (p = 0.150, r= -0.229). Kesimpulan: Tidak ada hubungan antara kadar TSH dan kadar ureum pada pasien TB paru di BKPM Purwokerto.
Kepadatan dan Dominasi Pinjal pada Beberapa Jenis Tikus dan Habitat di Daerah Enzootik Pes di Kabupaten Pasuruan, Jawa Timur Cahyaningrum, Winda Rahma; Wardani, Dita Pratiwi Kusuma; Ristiyanto, Ristiyanto; Almanfaluthi, Muhammad Luthfi; Handayani, Farida Dwi
Jurnal Sain Veteriner Vol 42, No 2 (2024): Agustus
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.95362

Abstract

Fleas are hemophagous insects that spread the Yersinia pestis bacteria that causes bubonic plague through the bites of infected fleas. The purpose of this study was to determine the density, dominance, and infestation of larvae in several types of rodents and habitats in the Pes enzootic area. This research was conducted in May–June 2023 in Pasuruan Regency, East Java. The data analysis method used was descriptif. Samples of rat fleas were taken from rats captured in residential, garden, and forest habitats. The results showed that six species of small mammals were captured, namely, the Muridae family consisting of Niviventer fulvescens, Rattus exulans, Rattus tanezumi, and Rattus tiomanicus; the Erinaceidae family, namely Helomys suillus; and the Soricidae family, namely Suncus murinus, with the highest trap success in residential habitats by 10.9% and the highest density of rats in residential and garden habitats. The larval species obtained were Xenopsylla cheopis and Stivalius cognatus, with the highest flea infestation in the rat species Rattus exulans female (300%) and Rattus tanezumi female (64.2%).
Co-Authors Almanfaluthi, Muhammad Lutfhi Amalia Ovi Mustika Seno Ambarwati, Dewi Annisa Nur Chaeni Aprianto . Arif Mulyanto Arif Mulyanto Arif Mulyanto, Arif Atika Nur Azizah ATIKA NUR AZIZAH Cahyaningrum, Winda Rahma Chaeni, Annisa Nur Dewi Kristiya Nugra Heny Dhanti, Kurnia Ritma Dhanti, Kurnia Ritma Dina Aristya Purdiani EKANIASARI, MEVIANA DEA Farida Dwi Handayani Firman Jaelani HAMNA FATHIA ZAHRA Handayani Narendo Putri handayani, Farida Heny, Dewi Kristiya Nugra Ika Wulan Nuri Anggreani Ikhsan Mujahid Ikhsan Mujahid Ikhsan Mujahid IKHSAN MUJAHID Indah Mulyani Ismi Andina Pertiwi Isna Hikmawati Isna Hikmawati ISNA HIKMAWATI Janatin Nur Aripin JANG JAYA, NABELA PUTRI Ketut Tirtayasa Kurnia Ritma Dhanti Kurniawan Kurniawan Kurniawan Linda Wijayanti Listiyowati, Tanti M Luthfi Almanfaluthi M. Luthfi Almanfaluthi Mika'il, Hikam Minto Rahaju Minto Rahaju Muhammad Lutfhi Almanfaluthi Muhammad Luthfi Muhammad Luthfi Almanfaluthi Muhammad Luthfi Almanfaluthi Muhammad Luthfi Almanfaluthi Muhammad Luthfi Almanfaluthi MUJIONO, TIMBUL Nadia Ega Haliza Nuri Anggreani, Ika Wulan Nurul Badriyah Nurul Badriyah Nurul Qomariyah Oei Stefani Yuanita Widodo OEI STEFANI YUANITA WIDODO Oktafian Diyas Tamtama Olivia Alfitri Qo'imah, Alamanda Nurul Qo’imah, Alamanda Nurul Rahaju, Minto RETNO SULISTIYOWATI Retno Sulistiyowati RETNO SULISTYOWATI Retno Sulistyowati Retno Sulistyowati Ristiyanto Ristiyanto Ristiyanto ROHMAH, JAZILATUR Santi Safitri Shely Ayu Lestari SUDARSONO, TANTRI ANALISAWATI Sudarsono, Tantri Analisawati Supriyadi Supriyadi Supriyadi Syafira Dian Ergiana Syifa Arrachmah Tantowi, Linda Yanuana Fanida Tantri Analisawati Sudarsono Tantri Analisawati Sudarsono Tantri Analisawati Sudarsono Tantri Analisawati Sudarsono Wijayanti, Linda Yunita Nurmalasari