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Hubungan Kadar C Reactive Protein dengan Jumlah Neutrofil Penderita Tuberkulosis Paru pada Fase Pengobatan 0 dan 6 Bulan di BKPM Purwokerto Nadia Ega Haliza; Dita Pratiwi Kusuma Wardani; Tantri Analisawati Sudarsono; Arif Mulyanto
Jurnal Surya Medika (JSM) Vol 8 No 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i2.3480

Abstract

Tuberkulosis merupakan penyakit yang disebabkan oleh Mycobacterium tuberculosis yang menyerang organ paru. Adanya peradangan Tuberculosis didalam tubuh ditandai dengan respon inflamasi. Respon inflamasi didalam tubuh dapat didiagnosa melalui pemeriksaan C Reactive Protein sebagai respon anti infeksi imun didalam tubuh seseorang. Biasanya adanya peningkatan kadar C Reactive Protein mengindikasikan infeksi yang tidak terkontrol. Selain pemeriksaan tersebut, pemeriksaan penanda lainnya dapat dilihat dari pemeriksaan hematologi seperti hitung jenis neutrofil. Tujuan penelitian ini untuk mengetahui hubungan kadar C Reactive Protein dengan jumlah neutrofil pada penderita tuberkulosis paru dengan fase pengobatan 0 dan 6 bulan di BKPM Kabupaten Banyumas. Penelitian ini menggunakan metode observasional analitik dengan rancangan Cross-sectional. Kemudian sampel dalam penelitian ini sebanyak 30 pasien tuberkulosis paru yang terdiri dari pasien fase pengobatan 0 dan 6 bulan. Terdapat hubungan kadar C Reactive Protein dengan jumlah neutrofil pada penderita tuberkulosis paru dengan fase pengobatan 0 dan 6 bulan (p = 0,014, r= 0,370)
Hubungan Kadar C-Reactive Protein dengan Jumlah Leukosit Penderita Tuberkulosis Paru pada Fase Pengobatan 0 dan 2 Bulan di BKPM Purwokerto Syafira Dian Ergiana; Dita Pratiwi Kusuma Wardani; Tantri Analisawati Sudarsono; Arif Mulyanto
Jurnal Surya Medika (JSM) Vol 8 No 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i2.3482

Abstract

Pulmonary tuberculosis is still a health problem to control in the world. This disease is caused by the bacterium Mycobacterium tuberculosis, which can cause inflammation that can trigger increased levels of C-Reactive Protein and leukocytes in the body. This study was conducted to determine the correlation between C-Reactive Protein levels and the number of leukocytes with treatment phases 0 and 2 months in BKPM Purwokerto. The design of this study was an analytical observation with a cross-sectional research design. Results from 30 pulmonary tuberculosis patients treated for 0 and 2 months showed a correlation between CRP levels and white blood cell counts (p = 0.002, r = 0.445). There is a moderate relationship between CRP levels and leukocyte counts. High levels of CRP correlate with increasing the number of leukocytes. More research is needed on the relationship between CRP levels and leukocyte counts with different phases of treatment.
Perbedaan Hasil Pemeriksaan Widal Metode Slide menggunakan Sampel Serum dan Plasma EDTA pada Mahasiswa Teknologi Laboratorium Medik Nurul Badriyah; Arif Mulyanto; Dita Pratiwi Kusuma Wardani; Retno Sulistyowati
Jurnal Analis Medika Biosains (JAMBS) Vol 9, No 2 (2022): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v9i2.283

Abstract

Demam tifoid merupakan penyakit infeksi akut usus halus yang disebabkan oleh bakteri S. typhi dan S. paratyphi. Penyakit demam tifoid termasuk penyakit menular. Penularan disebabkan karena makanan atau minuman yang disajikan tidak bersih dan tingkat higenis individu sanitasi lingkungan. Pemeriksaan widal merupakan suatu pemeriksaan serologis untuk mendeteksi antibodi terhadap bakteri S. typhi yang berdasarkan reaksi aglutinasi antara antigen dengan antibodi yang disebut aglutinin, dengan mengukur aglutinasi titer antibodi terhadap antigen O dan H dalam sampel. Penelitian ini bertujuan untuk mengetahui ada tidaknya perbedaan nilai titer pada pemeriksaan widal yaitu metode slide sampel serum dan plasma EDTA dengan rancangan cros sectional sampel yang digunakan sebanyak 26. Pada Mahasiswa Teknologi Laboratorium Medik. Data yang dihasilkan dianalisis dengan uji univariat dan uji pearson chi square. Hasil penelitian ini didapatkan hasil pada serum terbanyak yaitu pada titer 1/320 (61,5%) sedangkan pada plasma EDTA terbanyak yaitu pada titer 1/80 (46,2%) yang menunjukan nilai p velue 0,0247 (p >0,05), maka berdasarkan hasil tersebut dapat disimpulkan bahwa tidak terdapat perbedaan antara pemeriksaan widal menggunakan sampel serum dan plasma EDTA antigen O dan H.       
Efektivitas Kombinasi Ekstrak Lidah Buaya dan Lidah Mertua Terhadap Mortalitas Larva Aedes aegypti Handayani Narendo Putri; Dita Pratiwi Kusuma Wardani; Isna Hikmawati; Muhammad Luthfi Almanfaluthi
BALABA: JURNAL LITBANG PENGENDALIAN PENYAKIT BERSUMBER BINATANG BANJARNEGARA Volume 18 Nomor 1 Juni 2022
Publisher : Balai Penelitian dan Pengembangan Kesehatan Banjarnegara Badan Litbangkes Kemenkes RI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/blb.v18i1.5354

Abstract

The Dengue Haemoragic Fever (DHF) vector control with synthetic larvicide has an impact on health and environmental problems, so alternative plant-based insecticides are needed. The study aims to determine the larvicidal effect of a combination with Aloe vera extract and Sansivieria trifasciata on the mortality of Aedes aegypti larvae. This study was conducted with experimental design by a post-test only with control groups design consisting of five groups. Two groups are positive control (1% temephos) and negative control (0% concentration). The other three groups served as a combination of Aloe vera extract and S. trifasciata Prain in ratio of 75%:25% (P1), 50%:50% (P2), and 25%:75% (P3). A total of 375 larvae were introduced in this study with three replications and with observation time of 30 minutes, 1 hour, 3 hours, 6 hours, 12 hours, 24 hours until totally died 100%. The mortality of Aedes aegypti larvae were analyzed by Kruskal Wallis and probit analysis to calculate LC50 and LC90. The larvae totally died 100% after 12 hours of exposure. There are significant differences in the mortality of Ae. aegypti larvae after administration of a combination with Aloe vera extract and S. trifasciata Prain. The P1 group (The combination with Aloe vera extract and S. trifasciata Prain with a ratio of 75%:25%) was the most effective in mortality of Ae. aegypti larvae. The LC50 value is 0.517% while the LC90 value is 2.121% within 6 hours. The combination group of Aloe vera extract and mother-in-law's tongue with a ratio of 75%:25% was the most effective in causing mortality of Ae. aegypti within 6 hours.
Kombinasi Minyak Kayu Putih dan Jeruk Nipis terhadap Mortalitas Pediculus humanus capitis Janatin Nur Aripin; Dita Pratiwi Kusuma Wardani; M Luthfi Almanfaluthi; Isna Hikmawati
BALABA: JURNAL LITBANG PENGENDALIAN PENYAKIT BERSUMBER BINATANG BANJARNEGARA Volume 18 Nomor 1 Juni 2022
Publisher : Balai Penelitian dan Pengembangan Kesehatan Banjarnegara Badan Litbangkes Kemenkes RI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/blb.v18i1.5357

Abstract

The use of synthetic chemical pediculicides is known to have side effects and the occurrence of resistance so plant-based pediculicides are needed to kill Ph. capitis. Eucalyptus and lime oil are known to have an effect in killing Ph. capitis. The purpose of this study was to determine the effectiveness of the combination of eucalyptus and lime oil on the mortality of Ph. capitis. This study was conducted in a true experimental with a post-test-only control group design in May 2021. This study consisted of 5 treatment groups, one group as a positive control (permethrin 1%), one group as a negative control (aquadest), and 3 groups received treatment with a combination of eucalyptus and lime oil in the proportions of 1:3 (25 ml of eucalyptus oil: 75 ml of lime juice), 1:1 (50 ml of eucalyptus oil: 50 ml of lime juice) and 3: 1 (75 ml eucalyptus oil: 25 ml lime juice). It was repeated 3 times so that the total sample was 150 Ph. capitis which was observed every 5 minutes for 1 hour. The research data were analyzed using the Kruskal-Wallis test and continued with the Posthoc Mann-Whitney U test. Mortality of Ph. capitis in the combination group the most effective was the combination of 75% eucalyptus oil and 25% lime oil in the 5th-minute observation of 100% mortality compared to the control group and other groups.
Perbandingan Kadar C-Reactive Protein Terhadap Fase Pemberian Obat Anti Tuberkulosis Amalia Ovi Mustika Seno; Dita Pratiwi Kusuma Wardani; Supriyadi Supriyadi; Arif Mulyanto
THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Vol 5, No 2 (2022): The Journal Of Muhammadiyah Medical Laboratory Technologist
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmlt.v5i2.10623

Abstract

Pulmonary tuberculosis is a disease caused by Mycobacterium tuberculosis. C-Reactive Protein (CRP) is produced in the body by the liver in response to inflammation caused by Mycobacterium tuberculosis infection. CRP as the main mediator of the non-specific immune system, and the concentration will increase to 1000 times higher than normal value in the event of tissue injury or infection. The aim of this study was to determine the comparison of CRP levels to the phase of anti-tuberculosis drug administration in pulmonary tuberculosis patients. The study was conducted by cross sectional study with a semi-quantitative method in June - July 2020 in Purwokerto Community Lung Health Center. The number of samples as much as 24 TB patients which is 12 TB patients in 0 month and 12 TB patients in 6 months. Data were analyzed by Mann Whitney Test. The mean rank in 0 month was 18.08 with median (min-max) 12 (12-24) mg / dL, whereas mean rank for 6 months was 6.92 with median (mix-max) was 0 (0- 12) mg / dL. Serum CRP levels in pulmonary TB patients in the 0-month treatment phase are higher than CRP levels in the 6-month treatment phase (p = 0,000).
Hubungan Kadar C Reactive Protein dengan Jumlah Neutrofil Penderita Tuberkulosis Paru pada Fase Pengobatan 0 dan 6 Bulan di BKPM Purwokerto: Relationship Between C Reactive Protein Levels and the Number of Neutrophils in Pulmonary Tuberculosis Patients with Phases 0 and 6 Months at BKPM Purwokerto Nadia Ega Haliza; Dita Pratiwi Kusuma Wardani; Tantri Analisawati Sudarsono; Arif Mulyanto
Jurnal Surya Medika (JSM) Vol. 8 No. 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i2.3480

Abstract

Tuberkulosis merupakan penyakit yang disebabkan oleh Mycobacterium tuberculosis yang menyerang organ paru. Adanya peradangan Tuberculosis didalam tubuh ditandai dengan respon inflamasi. Respon inflamasi didalam tubuh dapat didiagnosa melalui pemeriksaan C Reactive Protein sebagai respon anti infeksi imun didalam tubuh seseorang. Biasanya adanya peningkatan kadar C Reactive Protein mengindikasikan infeksi yang tidak terkontrol. Selain pemeriksaan tersebut, pemeriksaan penanda lainnya dapat dilihat dari pemeriksaan hematologi seperti hitung jenis neutrofil. Tujuan penelitian ini untuk mengetahui hubungan kadar C Reactive Protein dengan jumlah neutrofil pada penderita tuberkulosis paru dengan fase pengobatan 0 dan 6 bulan di BKPM Kabupaten Banyumas. Penelitian ini menggunakan metode observasional analitik dengan rancangan Cross-sectional. Kemudian sampel dalam penelitian ini sebanyak 30 pasien tuberkulosis paru yang terdiri dari pasien fase pengobatan 0 dan 6 bulan. Terdapat hubungan kadar C Reactive Protein dengan jumlah neutrofil pada penderita tuberkulosis paru dengan fase pengobatan 0 dan 6 bulan (p = 0,014, r= 0,370)
Hubungan Kadar C-Reactive Protein dengan Jumlah Leukosit Penderita Tuberkulosis Paru pada Fase Pengobatan 0 dan 2 Bulan di BKPM Purwokerto Syafira Dian Ergiana; Dita Pratiwi Kusuma Wardani; Tantri Analisawati Sudarsono; Arif Mulyanto
Jurnal Surya Medika (JSM) Vol. 8 No. 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i2.3482

Abstract

Pulmonary tuberculosis is still a health problem to control in the world. This disease is caused by the bacterium Mycobacterium tuberculosis, which can cause inflammation that can trigger increased levels of C-Reactive Protein and leukocytes in the body. This study was conducted to determine the correlation between C-Reactive Protein levels and the number of leukocytes with treatment phases 0 and 2 months in BKPM Purwokerto. The design of this study was an analytical observation with a cross-sectional research design. Results from 30 pulmonary tuberculosis patients treated for 0 and 2 months showed a correlation between CRP levels and white blood cell counts (p = 0.002, r = 0.445). There is a moderate relationship between CRP levels and leukocyte counts. High levels of CRP correlate with increasing the number of leukocytes. More research is needed on the relationship between CRP levels and leukocyte counts with different phases of treatment.
Hubungan Kadar C-Reactive Protein (CRP) dengan Jumlah Limfosit pada Pasien TB Paru di BKPM Purwokerto: Relationship of C-Reactive Protein (CRP) Levels with Lymphocyte TB Patiens at BKPM Purwokerto Santi Safitri; Tantri Analisawati Sudarsono; Dita Pratiwi Kusuma Wardani; Linda Wijayanti
Jurnal Surya Medika (JSM) Vol. 8 No. 3 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i3.3564

Abstract

Tuberculosis is a chronic infectious disease that attacks the lung parenchyma. Pulmonary TB is a chronic disease caused by the bacterium Mycobacterium tuberculosis. Pulmonary TB is classified into Pulmonary TB and Extra Pulmonary TB. The prevalence of TB globally is 10 million people; Indonesia ranks second after China and India. This study aims to determine the relationship between levels of C-Reactive Protein (CRP) with the number of lymphocytes in patients with pulmonary TB at BKPM Purwokerto. The research design was in the form of an analytical observational design with an analytical cross-sectional design. The data on the characteristics of the subjects were obtained by filling in the information content, while the levels of C-Reactive Protein (CRP) were used quantitatively and qualitatively, and the number of lymphocytes was measured using a hematology analyzer. There were 30 respondents (60% male and 40% female). There is a relationship with Spearman's correlation test with a value of r = -0.466 and p <0.0001.
PENINGKATAN KEWASPADAAN DALAM PENCEGAHAN KEJADIAN DEMAM BERDARAH DENGUE DAN TOKSOPLASMOSIS PADA ANGGOTA RANTING AISYIYAH KARANG PUCUNG KECAMATAN PURWOKERTO SELATAN Dita Pratiwi Kusuma Wardani; Kurniawan Kurniawan
PROSIDING SEMINAR NASIONAL LPPM UMP Vol 1 (2019): PROSIDING SEMINAR NASIONAL LPPM UMP 2019
Publisher : Lembaga Publikasi Ilmiah dan Penerbitan (LPIP)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kejadian demam berdarah dengue masih menjadi perhatian tidak hanya bagi pemerintah, namun menjadi perhatian masyarakat Indonesia. Demam berdarah dengue yang tidak segera mendapat penanganan dapat mengakibatkan kematian sedangkan prevalensi dari tahun ke tahun selalu mengalami kenaikan yang signifikan. Padahal sering dilakukan Pemberantasan Sarang Nyamuk (PSN) secara berkala. Begitu pula dengan kasus tokspolasmosis yang menyerang wanita usia subur sehingga perlu menjadi perhatian karena toksoplasmosisdapat menyebabkan keguguran bagi wanita hamil bahkan menyebabkan kecacatan pada janin. Ranting Aisyiyah Karang Pucung Kecamatan Purwokerto Selatan merupakan kumpulan ibu-ibu yang aktif melakukan kegiatan pengajian dan diskusi. Belum pernah dilakukan penyuluhan mengenai kewaspadaan pencegahan kejadian demam berdarah dengue dan toksoplasmosis sehingga timbul inisiatif untuk memberikan edukasi mengenai pencegahan kejadian demam berdarah dan toksoplasmosis. Kegiatan ini diharapkan dapat memberikan kontribusi positif anggota Aisyiah berperan penting dalam kepedulian terhadap lingkungan sekitar terutamadalam hal pencegahan kejadian demam berdarah dan toksoplasmosis.
Co-Authors Almanfaluthi, Muhammad Lutfhi Amalia Ovi Mustika Seno Ambarwati, Dewi Annisa Nur Chaeni Aprianto . Arif Mulyanto Arif Mulyanto Arif Mulyanto, Arif Atika Nur Azizah ATIKA NUR AZIZAH Cahyaningrum, Winda Rahma Chaeni, Annisa Nur Dewi Kristiya Nugra Heny Dhanti, Kurnia Ritma Dhanti, Kurnia Ritma Dina Aristya Purdiani EKANIASARI, MEVIANA DEA Farida Dwi Handayani Firman Jaelani HAMNA FATHIA ZAHRA Handayani Narendo Putri handayani, Farida Heny, Dewi Kristiya Nugra Ika Wulan Nuri Anggreani Ikhsan Mujahid Ikhsan Mujahid IKHSAN MUJAHID Ikhsan Mujahid Indah Mulyani Ismi Andina Pertiwi Isna Hikmawati Isna Hikmawati ISNA HIKMAWATI Janatin Nur Aripin JANG JAYA, NABELA PUTRI Ketut Tirtayasa Kurnia Ritma Dhanti Kurniawan Kurniawan Kurniawan Linda Wijayanti Listiyowati, Tanti M Luthfi Almanfaluthi M. Luthfi Almanfaluthi Mika'il, Hikam Minto Rahaju Minto Rahaju Muhammad Lutfhi Almanfaluthi Muhammad Luthfi Muhammad Luthfi Almanfaluthi Muhammad Luthfi Almanfaluthi Muhammad Luthfi Almanfaluthi Muhammad Luthfi Almanfaluthi MUJIONO, TIMBUL Nadia Ega Haliza Nuri Anggreani, Ika Wulan Nurul Badriyah Nurul Badriyah Nurul Qomariyah Oei Stefani Yuanita Widodo OEI STEFANI YUANITA WIDODO Oktafian Diyas Tamtama Olivia Alfitri Qo'imah, Alamanda Nurul Qo’imah, Alamanda Nurul Rahaju, Minto RETNO SULISTIYOWATI Retno Sulistiyowati Retno Sulistyowati RETNO SULISTYOWATI Retno Sulistyowati Ristiyanto Ristiyanto Ristiyanto ROHMAH, JAZILATUR Santi Safitri Shely Ayu Lestari SUDARSONO, TANTRI ANALISAWATI Sudarsono, Tantri Analisawati Supriyadi Supriyadi Supriyadi Syafira Dian Ergiana Syifa Arrachmah Tantowi, Linda Yanuana Fanida Tantri Analisawati Sudarsono Tantri Analisawati Sudarsono Tantri Analisawati Sudarsono Tantri Analisawati Sudarsono Wijayanti, Linda Yunita Nurmalasari