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Efek Ekstrak Metanol dan Partisi dari Kulit Batang Kayu Jawa (Lannea coromandelica Houtt. Merr.) terhadap Pertumbuhan Sel HeLa dan MCF-7 Nadyah Haruna; Zakiah Anugerah Hamzah; Syamsuri Syakri; Isriany Ismail; Nursalam Hamzah
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 1 No 2 (2018)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (218.896 KB) | DOI: 10.24252/djps.v1i2.11338

Abstract

Tujuan penelitian ini adalah menentukan efek ekstrak metanol dan partisi kulit batang kayu jawa dalam menghambat pertumbuhan sel kanker HeLa dan sel kanker MCF-7. Simplisia kulit kayu dimaserasi menggunakan pelarut metanol. Ekstrak kemudian dipartisi secara partisi cair padat menggunakan pelarut heksan. Pemisahan menghasilkan partisi larut heksan dan partisi tidak larut heksan. Pengukuran aktivitas inhibisi pertumbuhan sel dilakukan menggunakan metode MTT Assay terhadap sel HeLa, sel MCF-7 dan sel Vero. Senyawa yang dikandung diidentifikasi dengan beberapa pereaksi golongan. Hasil penelitian menunjukkan bahwa ekstrak metanol, partisi tidak larut heksan dan partisi larut heksan dapat menghambat pertumbuhan sel kanker Hela dengan nilai indeks selektivitas, berturut-turut, 2,04; 1,85 dam 4,19. Sedangkan untuk sel MCF-7, indeks selektivitas, berturut-turut, 1,91; 1,44 dan 2,13. Partisi larut heksan dapat memiliki potensi sebagai antikanker dengan selektivitas yang baik.
ANALISIS FAKTOR RISIKO KEJADIAN STUNTING PADA BALITA USIA 6 BULAN – 23 BULAN DI PUSKESMAS PEKKAE KECAMATAN TANETE RILAU KABUPATEN BARRU TAHUN 2020 Nur Alda Fadillah; Andi Alifia Ayu Delima; Rauly Rahmadhani; Nadyah Haruna; Ibrahim Manda
Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran Vol 5, No 2 (2022): ILMU KEDOKTERAN
Publisher : Journal Medical Universitas muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26618/aimj.v5i2.7937

Abstract

Stunting is ashort body condition according to the age which exceed the 2 SD (Standard Deviation) deficit below the median length standard or the height of the age. A toddler with stunting shows the existence of long-term nutritional problems or chronic nutrition that can be affected by the condition of the mother or future mother, fetal period and infancy or toddler period, including the disease suffered during infancy period. The aim of this research was to find out the risk factor of stunting to the child aged 6-23 months in working area of Pekkae health care, Tanete Rilau, Barru Regency. This research was a quantitative research with observational analytic method and crossectional design. Sampling was obtained by using purposive sampling technique. The total of sample were 98 toddlers and their mother as a respondent. The data were analyzed by using the Chi-square p0.05 in the SPSS program. The result of this research showed that there was a significant relationship between the history of complementary feeding (p-value 0.031;1.36), infectious disease (p-value 0.005;1.41),  mother’s knowledge of toddler nutrition (p-value 0.031;1.36) and economic factor (p-value 0.000; 2,71) toward the stunting. There was no significant relationship between the history of exclusive breastfeeding, toddler immunization, maternal height and the mother’s last education level toward this stunting with p-value 0.005. The most dominant factor in this research was family economic factor.Keywords : toddler, stunting, history of complementary feeding, history of infectious disease, mother’s education, mother’s knowledge, family economic factor.
MANAJEMEN ASUHAN KEBIDANAN INTRANATAL PATOLOGI DENGAN PERSALINAN LETAK SUNGSANG (LITERATUR REVIEW) Nur Dinda; Sitti Saleha; Nadyah Haruna
Jurnal Midwifery Vol 3 No 2 (2021): AUGUST
Publisher : Prodi Kebidanan Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jmw.v3i2.24345

Abstract

Pendahuluan Persalinan letak sungsang merupakan suatu kelainan patologis, dimana janin dilahirkan letak memanjang dengan kepala berada di fundus uteri dan bokong berada dibagian bawah kavum uteri. Persalinan letak sungsang adalah salah satu penyulit persalinan yang dapat menyebabkan kematian janin. Metode Menggunakan studi kepustakaan dan pengumpulan referensi yang kemudian dibuat menjadi Literatur review dengan menggunakan berbagai referensi literature dan membandingkan referensi satu dengan yang lainnya. Hasil Berdasarkan hasil penelitian-penelitian bahwa pemeriksaan untuk mendiagnosis persalinan letak sungsang dilakukan melalui pemeriksaan perut menggunakan manuver leopold yang dikombinasikan dengan pemeriksaan serviks, dan ultrasonografi. Kesimpulan Pertolongan persalinan letak sungsang dengan sectio caesarea maupun pervaginam dilakukan dengan banyak pertimbangan. diperlukan evaluasi kembali agar tindakan yang dilakukan terhadap pasien dengan kasus yang sesuai untuk kebutuhan medisnya.
Hubungan Pendidikan Dengan Kejadian Anemia Pada Ibu Hamil Di Puskesmas Pampang Kota Makassar: Relationship of Education Level with Anemia Events in Pregnant Women in Pampang Makassar City Hamraa Bachtiar; Nadyah Haruna; Andi Alifiyah Ayu Delima
Jurnal Midwifery Vol 5 No 1 (2023): FEBRUARY
Publisher : Prodi Kebidanan Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jmw.v5i1.35510

Abstract

Introduction Anemia during pregnancy is referred to as a "potential danger to mother and child" or "anemia is a potential danger to mother and child" so it is something that needs to be considered because it will have an impact on the health of the mother and child. Anemia can be influenced by internal and external factors, and education is one of the external factors that can influence the ability of pregnant women to receive and process health information during pregnancy. The pregnancy phase determines the ability of the child to be born, because development and growth are determined since the fetus is in the womb. Knowing about the incidence of anemia during pregnancy is something that really needs to be considered so that it is not only the responsibility of pregnant women but also the surrounding family who will accompany them throughout pregnancy. Method This study is a quantitative study with a cross sectional design, the sample technique uses purposive sampling with the total sample studied as many as 239 pregnant women and has fulfilled the research criteria. The research data was analyzed using the chi square test. Result This study obtained pregnant women who were anemic as much as 72.4% and the results of bivariate analysis showed that the level of education did not significantly affect the incidence of anemia in pregnant women with a p value of 0.258> 0.000. Conclusion This study shows that the level of education does not affect the incidence of anemia in pregnant women at Puskesmas Pampang Makassar City
HUBUNGAN ANEMIA DENGAN KEJADIAN KETUBAN PECAH DINI DI RUMAH SAKIT UMUM DAERAH BATARA SIANG PANGKEP PERIODE JANUARI 2019 – JUNI 2021 Sry Mulya Nur Fatimah; Saharuddin; Nadyah Haruna
Alami Journal (Alauddin Islamic Medical) Journal Vol 6 No 2 (2022): JULY
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/alami.v6i2.26945

Abstract

Premature rupture of membranes (PROM) is the rupture of the fetal membranes before the onset of labor. The actual cause of PROM is still unclear, as much as 8% of all pregnancies are considered to be PROM. It is also evident that the main factor that causes perinatal mortality and morbidity was PROM. Therefore, a quick intervention is needed to control mortality and morbidity rate. The major purpose of this research was to investigate and understand the relationship between anemia and premature rupture of membranes at Batara Siang Regional Hospital of Pangkep. The methogological approach used in this study was an analytical observational research design with a case control approach. The sample of this study was inpartu mothers. The mothers who were diagnosed with PROM were taken as main cases, and those who were not diagnosed with PROM were taken as controls. The data collection of this study was the secondary research data taken from the medical records of Batara Siang Hospital. The data analysis was conducted using univariate and bivariate techniques by utilizing the Chi-Square Test. The samples obtained from this study were 68 samples. Therefore, from the results of this study, it was apparent that there was a significant relationship between hemoglobin and hematocrit with the occurrences of PROM. From this study, it was concluded that there was a relationship between anemia and the incidence of KPD.
Faktor Risiko Riwayat Hipertensi dan Diabetes Mellitus Pada Ibu Hamil Terhadap Kejadian Preeklampsia di RSKD Ibu Anak Siti Fatimah 2021: Risk Factors for History of Hypertension and Diabetes Mellitus in Pregnant Women on Preeclampsia in Siti Fatimah Mother and Child Hospital 2021 Fachrul, Moch. Afif; Andi Irhamnia Sakina; Nadyah Haruna
Jurnal Midwifery Vol 6 No 2 (2024): AUGUST
Publisher : Prodi Kebidanan Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jmw.v6i2.44993

Abstract

Introduction Preeclampsia is a condition where a pregnant woman having hypertension that occurs after 20 weeks of gestation accompanied with impaired organ function which can be marked by proteinuria. To this day, preeclampsia pose a very dangerous threat to pregnancy and has become the leading cause of death on pregnant women. The purpose of this study was to determine the relationship between risk factor of history of hypertension and diabetes mellitus of pregnant woman with the incidence of preeclampsia at Siti Fatimah Makassar Woman and Children Regional Special Hospital in 2021. Method This study was an analytic observational study with a case control approach. The sampling method was the total sampling technique and 182 samples which 91 case and 91 control were obtained through medical records. Result The result showed that of the 182 sample, there were 73 pregnant women (80,2%) with history of hypertension who had preeclampsia, 9 pregnant woman (4,9%) with diabetes mellitus who had preeclampsia. Conclusion History of hypertension is a risk factor for the incidence of preeclampsia and diabetes mellitus is not the risk factor for the incidence of preeclampsia.
Hubungan Ketepatan Penggunaan Antibiotik dengan Lama Rawat dan Luaran pada Pasien Infeksi Saluran Pernapasan Anisa Lintang; Nadyah Haruna; Darmawansyih; Asrul Abdul Azis; Takdir
Alami Journal (Alauddin Islamic Medical) Journal Vol 9 No 1 (2025): JANUARY
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/alami.v9i1.49810

Abstract

Respiratory tract infections occur when germs or bacteria enter the respiratory tract and reproduce, developing symptoms. A significant proportion, around 40-60%, of patients with respiratory tract infections need antibiotic therapy due to the presence of viral and bacterial infections. Antibiotic resistance escalates the expenses of medical care, prolongs the duration of hospitalisation, and can elevate the likelihood of death. This study aims to establish the correlation between the utilisation of antibiotics and the duration of hospitalisation and outcomes in patients diagnosed with respiratory tract infections at the Makassar Hajj Hospital from 2021 to 2023. This study employs a quantitative approach and utilises a cross-sectional research methodology. The research sample consisted of 99 respondents diagnosed with respiratory tract infections. The data from their medical records were collected using the purposive sampling technique. The chi-square analysis of the data revealed a significant association between the length of stay and outcomes, with a p-value of less than 0.001. The data indicate a correlation between the use of antibiotics and the duration of hospitalisation and outcomes in patients with respiratory tract infections at the Makassar Hajj Hospital from 2021 to 2023.
Pengendalian Berat Badan Lahir Rendah (BBLR) dengan Pendekatan Asset Based Community Development (ABCD) di Puskesmas Kota Makassar Rosdianah Rahim; Nadyah Haruna; Muhammad Nur Alamsyah Rajab; Yusril Ihsanul
Alami Journal (Alauddin Islamic Medical) Journal Vol 9 No 1 (2025): JANUARY
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/alami.v9i1.42877

Abstract

Low Birth Weight (LBW) is a birth weight of less than 2500 grams which is an indicator of a child's growth and development until adulthood and describes the nutritional status obtained by the fetus while in the womb. The community's Asset Based Community Development (ABCD) approach is used to help achieve a common goal in controlling LBW, starting with asset identification, problem analysis, potential planning, implementation, and utilization. The focus of the research was the identification of human resource assets for controlling LBW. This is qualitative research using the ABCD approach with observation and in-depth interviews. The method for choosing informants is snowball sampling in the working area of ​​the Community Health Center in Makassar City in 2022. Based on the ABCD, this study identifies several assets involved in controlling LBW cases at the Community Health Center in Makassar City: Human Assets, namely Health services related to pregnant women's programs such as ANC visits, pregnant women's classes, and knowledge of pregnant women; Social assets, Physical assets, and Economic assets depend on the profession of each resident. These four assets are very supportive to control LBW cases in the Community Health Center in Makassar City.
EVALUATION OF HYPERTENSION PREVENTION & MANAGEMENT STRATEGIES: THE IMPACT OF ANTIHYPERTENSION BEVERAGES AND MORINGA TEA ON MOOD DEVELOPMENT AND IMMUNITY Jayadi, Yusma Indah; Hasbi Ibrahim; Nadyah Haruna
Homes Journal = Hospital Management Studies Journal Vol 6 No 1 (2025): Homes Journal
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Takalar Regency in 2017 the number of hypertension sufferers was 2969 (80%) with 927 men (28%) and 1769 women (61%). Moringa is one of the assets in Maccini Baji Hamlet. It is known that the Moringa plant contains all the nutrients needed to balance blood pressure. Objective: The purpose of this study was to evaluate education related to the prevention and management of hypertension as well as to foster the atmosphere of antihypertensive drinks from Moringa leaves. Method: This research is a quantitative study using purposive sampling technique related to counseling on the prevention and control of hypertension and building an atmosphere for antihypertensive drinks carried out by observation and in-depth interviews related to knowledge, attitudes and actions. Result: The results of the study proved the effect of the boiled water of Moringa leaves on blood pressure in hypertensive patients. The Wilcoxon Statistical Test was carried out at a significance level of α (0.05) with a (p) value of 0.000, so it can be said that there was a significant change between the Moringa leaf decoction and changes in blood pressure in hypertensive patients. Conclusion: Based on the analysis of the Friedmen test, it showed a significant value of 0.000 (p <0.05) so that it can be concluded that there was an increase before and after three months of counseling on prevention and control of hypertension.
Profil Bakteri dari Usap Tenggorok Penderita Infeksi Saluran Pernapasan Usia Sekolah Dasar di Puskesmas Tamalanrea Makassar Nomarihi Goraahe; Nadyah Haruna; Najamuddin Najamuddin; Andi Irhamnia Sakinah; Arifuddin Ahmad
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i1.4313

Abstract

Acute respiratory infection (ARI) is a condition that occurs in one or more areas of the human respiratory tract and is associated with the environmental conditions in which the patient resides. The most frequent cause of ARI is infection with Streptococcus pneumonia or Haemophilus influenza. In order to diagnose ARI by identifying the infectious agent responsible for its development, laboratory tests can be conducted on throat swab samples from patient who exhibit symptoms of ARI.. One of the objectives of this investigation was to ascertain the bacterial profile of children with ARI. This study is a descriptive cross-sectional investigation that utilised specimens from throat swabs of ARI patients in elementary school-age children who visited the Tamalanrea Makassar Health Centre between October 10, 2022, and November 10, 2022. The biopsy results were subsequently subjected to gramme staining and identification tests to ascertain the species of causative bacteria. In the 57 children, which consisted of 38 boys and 19 girls, the percentage of monobacterial findings was 49 (85.96%) and 8 (14.04) polymicrobial. Gram-positive bacteria were found 50.8% and gram-negative bacteria 49.2%, with Staphylococcus aureus being the most common cause.