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Journal : Jurnal Fitofarmaka Indonesia

GC-MS Analysis of Ginger Rhizome with Various Extraction Methods Syarif, Rezki Amriati; Faradiba, Faradiba; Alyanti, Tifani Kursya; Savitri, Triana Aulia
Jurnal Fitofarmaka Indonesia Vol 11, No 3 (2024): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION)
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v10i3.1105

Abstract

Ginger (Zingiber officinale) is a rhizome plant well-known as a spice and medicinal material. Either one of the bioactive components is an essential oil, which is efficacious in preventing and treating various diseases. This research aims to determine the percentage yield of extracts and GC-MS analysis of the percentage of the chemical content of essential oils of ginger with various extraction methods. Firstly, compounds from ginger rhizomes were extracted using maceration, ultrasonic, and distillation techniques, and the extracts were analyzed using GC-MS Spectrophotometer. The highest percentage extract yield from ultrasonic extraction was 21.29%, then maceration extraction was 6.26%, and distillation extraction was 5.00%. The GC-MS results showed that the secondary metabolite compounds from maceration, ultrasonics, and distillation contained zingiberol, zingiberin, shogaol, borneol, linalool, citral, geraniol, and E-citral. The zingiberol group of compounds was obtained with the highest percentage from ultrasonic extraction at 1.07%, then maceration extraction at 1.03%, and distillation extraction at 0.27%.
Pengaruh Variasi Metode Ekstraksi Jahe dan Serai terhadap Aktivitas Antiinflamasi pada Penghambatan Denaturasi Protein Faradiba, Faradiba; Syarif, Rezki Amriati Amriati; Khaira, A Tenri Mifta; Alyanti, Tifani Kursya
Jurnal Fitofarmaka Indonesia Vol 11, No 1 (2024): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v11i1.1184

Abstract

The content of secondary metabolites or chemical content in medicinal plants affects pharmacological activity. The level of chemical content is affected by the extraction method. Previous research has been conducted on the extraction of ginger and lemongrass using two methods, which include maceration and ultrasonic. The results obtained are differences in chemical content that have the potential to have anti-inflammatory activity. Ginger (Zingiber officinale) contains chemical compounds, including gingerol, shogaol, and zingeron. linalool, alpha-pinene, and sineol. Lemongrass (Cymbopogon citratus) contains citronellal, citronellol, geraniol, flavonoids, and tannins. The aim of this study was to compare the invitro anti-inflammatory activity of ginger and lemongrass extracts using two extraction methods: maceration and ultrasonic. The research method consists of two stages, i.e. extraction of samples using maceration and  ultrasonic methods. The second stage is testing the anti-inflammatory activity against BSA (Bovine Serum Albumin) denaturation of extracts from maceration and ultrasonic methods with the parameter of percentage value to be more than 20%. The results obtained from ginger and lemongrass extracts showed the percentage value of inhibition at concentrations of 10 µg/mL, 12.5 µg/mL, 17.5 µg/mL, and 20 µg/mL are all more than 20%. The ultrasonic extraction of ginger showed a more linear inhibition percentage than the results of maceration. Macerated lemongrass extract showed a more linear percentage inhibition than ultrasonic results.
GC-MS Analysis of Lemongrass with Various Extraction Methods Syarif, Rezki Amriati; Faradiba, Faradiba; Khaira, A. Tenri Mifta; Nirwana, Nirwana
Jurnal Fitofarmaka Indonesia Vol 10, No 3 (2023): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION)
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v10i3.1108

Abstract

Lemongrass (Cymbopogon citratus) is one plant producing bioactive essential oil. This research aims to determine the percentage yield of extracts and GC-MS analysis of chemical compound profiles of lemon grass with various extraction methods. Lemongrass bioactive compounds are extracted using maceration, ultrasonic, and distillation. The highest percentage extract yield was from maceration extraction, namely 14.83%, ultrasonic extraction was 4.68%, and distillation extraction was 6.00%. The GC-MS results showed that the secondary metabolite compounds resulting from maceration, ultrasonic, and distillation contained geraniol, citronellal, and citronellol. The citronella compound group was obtained with the highest percentage from distillation extraction at 14.83%, followed by ultrasonic extraction at 2.23% and maceration extraction at 0.37%.
Co-Authors Abdullah, Magfirah Alyanti, Tifani Kursya Andreas Rian Nugroho Asep Edi Sukmayadi Asni Amin Aswar, Jumalia Audia Triani Olii, Audia Triani Bintang R. Simbolon Chyntia Clarinda Dedi Juliasman Sakatsila Dewi Yuliana Diaz Jubairy Prabowo Erni Murniarti Erni Murniarti Fadliyah, Hilyatul Fransiskus Assisi B Hadi Saputra Handayani, Ida Sri Hasanudin, Nurlaila Hasfikasari, Prity Heriatmo, Nadia Larasinta intan permata sari Ivanawati, Anselma Jei Tipoani Sinaga Kase, Alfa Graciani Khaira, A Tenri Mifta Khaira, A. Tenri Mifta Laia, Setiana Lase, Fan Damai Sejahtera Lumbantobing, Septina Severina Lutfan Lazuardi Manogari Sianturi Manogari Sianturi Manogari Sianturi Manullang, Nathasya Grisella Mariana Gu Minawati Minawati Muammar Fawwaz Napitupulu, Revaldo Ngia Masta Nirwana, Nirwana Nomleni, Marteda Veronika Novalina Nurmala, Andi Arifah Nurwahyuni, Atik Nya Daniaty Nya Daniaty Malau Olla, Yufran Meliando Philipus Philipus Piter Honirius Naitaunus Pratita, Rasta Naya Rais Razak, Rais Ratna Santi Rezki Amriati Syarif, Rezki Amriati Ririn Aquarina Ririn Ririn Sakatsila, Dedi Juliasman Samuel Gideon Satibi Satibi Savitri, Triana Aulia Sekri Ambu, Reggen Seprianus Seprianus Septina Severina Lumbantobing Septina Severina Lumbantobing Septina Severina Lumbantobing Septina Severina Lumbantobing Shafira Shafira, Shafira Siahaan, Chontina Sri Rahayu Tri Astuti St Fatimah Azzahra, St Fatimah Stivens Situmeang, Bramcov Sumiati Sumiati Sumiati Sumiati Syarif, Rezki Amriati Amriati Taat Guswantoro, Taat Winda Wahyuni Yohanes, Andreas Yonas Firdinal Silaban Yoshua, Steven Yufran Meliando Olla Yulianto, Yuni Zakinah Zainal Abidin Zealfiana, Gracia Zebua, Tesalonika Febriani