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The Role of Neutrophil to Lymphocyte Ratio (NLR) and Platelet to Lymphocyte Ratio (PLR) in Appendicitis Heriyanto, Moch Junaidy; Ratnaningsih, Tri; Heriyanto Putri, Rona Hafida; Fatimah, Bunga; Astuti, Fardhiasih Dwi
JBN (Jurnal Bedah Nasional) Vol 8 No 1 (2024): JBN (Jurnal Bedah Nasional)
Publisher : Program Studi Ilmu Bedah, Fakultas Kedokteran Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JBN.2024.v08.i01.p01

Abstract

Aim: Predictive values of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are associated with poor outcomes in several diseases. Furthermore, there has been limited publication of those parameters in appendicitis patients in Indonesia. This study aims to evaluate the role of NLR and PLR in differentiating complicated appendicitis and uncomplicated appendicitis. Methods: The design of this study is a retrospective using medical records of appendicitis patients from January 1, 2016, to December 31, 2020, conducted at PKU Muhammadiyah Bantul Hospital. There are 408 data on appendicitis patients that can be analyzed. Results: The WBC, neutrophils, NLR, and PLR was significantly higher in the complicated appendicitis group than in the uncomplicated group [11,5 (3.79-35.2) vs. 8.42 (3.32-39.30), p<0.0001; 8.63 (2.359-2.647) vs. 5.446 (1.691-35.960), p<0.0001; 5.65 (0.95-23.86) vs.3.82 (0.81-23.86), p<0.0001; 168.57 (37.27-974.03) vs.139.40 (56.84-1274.31), p<0.0001, respectively] followed by a significantly lower lymphocyte count [1.709 (0.154-5.71) vs. 2.094 (0.401-5.812), p<0.0001, respectively]. The area under the receiver operating characteristic (ROC) curve, cutoff point, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and likelihood ratio of NLR for diagnosis of complicated appendicitis were 0.76, >2.84, 75.21%, 62.65%, 74.6%, 63.4%, 2.01, 0.40, respectively. In contrast, an area under ROC curve, cutoff point, sensitivity, specificity, PPV, NPV, and likelihood ratio of PLR for differentiating complicated and uncomplicated appendicitis were 0.605, >140.6, 65.70%, 51.81%, 66.5%, 50.9%, 1.36, and 0.66 respectively. Conclusion: The cutoff values of NLR (>2.84) and PLR (>140.6) were significant diagnostic parameters for complicated appendicitis (p = 0.0001). Hence, NLR and PLR can assist in diagnosing complicated appendicitis.
The Effect of Health Education on Knowledge of the Dangers of Smoking in Students of SMK Negeri 4 Yogyakarta Prisilla Maya Heni Pratiwi; Putri, Rachma Greta Perdana; Sukirto, Novi Wijayanti; Astuti, Fardhiasih Dwi
Ahmad Dahlan Medical Journal Vol. 5 No. 1 (2024): May 2024
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Smoking is the activity of smoking tobacco rolls wrapped in paper or nipa leaves and then burning and producing smoke. In thesurvey results of the Ministry of Health of the Republic of Indonesia, the risk of smoking behavior in junior and senior high school students in Indonesia in 2015 was 32.82% in male students. Smoking habits lead to health risk for cardiovascular and respiratory diseases and many types of cancer. Smokers have moderate knowledge of tobacco. The study's aim is to examine the effect of health education on knowledge of the dangers of smoking in students of SMK Negeri 4 Yogyakarta. This study utilized a pre-experimental design method with One-Group Pretest-Posttest design approach. The study sample consisted of 127 students who met inclusion and exclusion criteria in class X students of SMK Negeri 4 Yogyakarta. The pretest and post-test scores varied from 22 to 29 with increased scores of the post-test’s trend. Statistical analysis using chi-square test analysis showed a p-value of 0.000 (<0.05). These results suggest that there is an influence between health education on knowledge of the dangers of smoking in students of SMK Negeri 4 Yogyakarta
Challenges in implementing dengue surveillance in Bantul District Special Region of Yogyakarta, Indonesia Astuti, Fardhiasih Dwi; Widyaningsih, Vitri; Pamungkasari, Eti Poncorini; Subijanto, Achmad Arman
International Journal of Public Health Science (IJPHS) Vol 14, No 1: March 2025
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v14i1.24626

Abstract

The surveillance system is a source of information for policymaker to address the dengue outbreak. However, there was a lack of information on the effectiveness of dengue surveillance system in reporting the outbreak. This study aims to assess dengue surveillance activities in Bantul District, Special Region of Yogyakarta, Indonesia, one of the districts with a high burden of dengue, to provide information on current effectiveness and need assessment for further improvement for dengue surveillance system. This qualitative study was conducted in Bantul District, Special Region of Yogyakarta. The assessment approach was based on the input-processoutput-outcome (IPOO) model. The study participants were selected based on purposive sampling. Data were collected through interviews. Eight program holder surveillance were interviewed based on the interview guide. The surveillance system in Bantul Regency already utilizes electronic reporting. Reporting cases of dengue uses the system for surveillance of outbreak events (SISKLB). Analysis and interpretation are done to monitor progress in cases. The follow-up evaluation ceses is vector control to prevent the spread of the case. The incidence of dengue is still higher than the national rate. The case fatality rate (CFR) for dengue is <1%; CFR has hit its target. The larvae-free rate hasn't reached its target yet. Optimizing electronic reporting can improve the quality of information used as a reference in decision-making. SISKLB was created for timely reporting and monitoring of dengue cases. Monitoring available data laboratory can be used as a quick response to take action to prevent an increase in cases.
PENGARUH DOSIS FRUKTOSA TERHADAP INDEKS MASSA TUBUH, PROFIL GLUKOSA DARAH DAN KADAR TRIGLISERID (Studi pada Tikus Wistar yang Diinduksi High Fat Fructose Diet ) Sunarti, Sunarti; Astuti, Fardhiasih Dwi; Bintanah, Sufiati
Jurnal Gizi Vol 10, No 2 (2021): Jurnal Gizi UNIMUS
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jg.10.2.2021.53-59

Abstract

Fructose or often called fruit sugar is one part of simple carbohydrates calledFructose or often called fruit sugar is one part of simple carbohydrates called monosaccharides (Almatsir 2009). Currently, many food and beverage industries use fructose sugar as a sweetener. (Prahstuti 2011). Consumption of high-fructose products of more than 85 grams per day or more than 25% of caloric needs can lead to increased triglyceride levels and insulin resistance (Prahastuti 2011). The purpose of this study was to evaluate changes in obesity status, fasting blood glucose levels and triglyceride levels in wistar rats induced with a high fat fructose diet, by giving different doses.Research methods.The design in this study was a Randomized Control Trial (RCT), double bline pre post control design using male wistar rats, aged 6-7 weeks weighing 90-150 grams, totaling 15 individuals divided into 3 groups. Group 1 is a group of rats fed HFFD with 1% fructose, group 2 is rats fed HFFD with 2% fructose, group 3 is rats fed standard feed. Before the treatment, adaptation was carried out for 1 week, after that a pre-test was carried out which included measurements of body weight, body length, fasting data glucose levels, and triglyceride levels. The treatment was given for 60 days, in the middle the measurements of body weight, length, fasting data glucose levels, and triglyceride levels were also carried out. The research location was in the clinical pathology laboratory, Faculty of Pharmacy, Muhammadiyah University, Surakarta.The results of the study The administration of fructose at a dose of 2% / kg BW increased fasting blood glucose and triglyceride levels higher than the administration of 1%. kgBB. Upgrade has started since day 30Keywords: Fructose dose, Body Mass Index, fasting blood glucose level, Triglyceride level, Wistar rats, induced High fat fructose diet
Education Education on the Role of the Young Generation in Stunting Prevention, Small Steps for a Big Impact in Reducing Stunting Incidence: Edukasi Pentingnya Peran Remaja dalam Pencegahan Stunting di Patehan, Kraton, Kota Yogyakarta Rokhmayanti, Rokhmayanti; Astuti, Fardhiasih Dwi; Hastuti, Siti Kurnia Widi; Martini, Titim
Jurnal Pengabdian Kesehatan Komunitas Vol. 3 No. 1 (2023): JPKK Edisi April 2023
Publisher : STIKes Hang Tuah Pekanbaru

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25311/jpkk.Vol3.Iss1.1438

Abstract

The way to prevent stunting is by providing education at the adolescent stage. Increased understanding of adolescents is expected to have an impact on nutritional status which has an impact on the phase of pregnancy and the first 1,000 days of birth. The method in this counseling is lectures using narration, pictures, and videos. The results of this study revealed that adolescents in RW 09 Kelurahan Taman already know about stunting prevention. Knowledge of stunting prevention is to be applied in these adolescents' lives so that they can prevent stunting in their children Abstrak Stunting menjadi salah satu masalah gizi di Indonesia yang disebabkan status gizi anak dan ibu yang rendah. Meningkatkan pemahaman calon ibu khususnya pada fase remaja menjadi salah satu upaya pencegahan dalam mengatasi stunting.Tujuan dari pengabdian ini adalah meningkatkan pengetahuan tentang stunting pada remaja sebagai upaya pencegahan. Metode dalam penyuluhan ini adalah ceramah dengan menggunakan narasi, gambar, dan video. Hasil dari penelitian ini diketahui bahwa setelah penyuluhan mayoritas semua pertanyaan dapat dijawab dengan benar 100% oleh remaja di RW 09 Patehan, Kraton, Yogyakarta. Sehingga pengetahuan pencegahan stunting yang teraplikasikan dalam kehidupan remaja dapat mencegah kejadian stunting pada anak mereka.
Risk factors of COVID-19 incidence in Bantul Regency, Indonesia Wardani, Siska; Astuti, Fardhiasih Dwi
International Journal of Public Health Science (IJPHS) Vol 12, No 3: September 2023
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v12i3.22776

Abstract

Coronavirus disease 2019 (COVID-19) was a public health problem in Indonesia. The highest number of COVID-19 cases in Special Region of Yogyakarta in 2021 was in Bantul Regency. The epidemiological description based on the person, place, time, and risk factors for COVID-19 in Bantul Regency in 2021 has yet to be described. This study aimed to determine risk factors, person, place, and time characteristics associated with the incidence of COVID-19 in the Bantul Regency in 2021. This study employed a cross-sectional design with secondary data on COVID-19 cases in Bantul Regency in 2021. Furthermore, 80,322 samples were analyzed and confirmed COVID-19 was 53,506 cases (66.61%). The case fatality rate was 2.72%. The highest age positive for COVID-19 is <65 years (92.31%), 53.83% of cases were female, and the district of Banguntapan with the highest rate of COVID-19 (15.11%). The peak of cases occurred in July, 2021. There is a relationship between close contact, travel history, age, and gender with the incidence of COVID-19 (p<0.001). The most significant risk factors were close contact (OR=8.657), travel history (OR=3.034), gender (OR=1.147), and age (OR=0.889). Close contact has the most significant association with the incidence of COVID-19, followed by travel history and gender.
GAMBARAN KEJADIAN COVID-19 DI WILAYAH KERJA PUSKESMAS UMBULHARJO I (PERIODE BULAN MEI – AGUSTUS 2021) Rokhmayanti, Rokhmayanti; Martini, Titim; Padmawati, Ike Lukita; Astuti, Fardhiasih Dwi; Hastuti, Siti Kurnia Widi
Jurnal Penelitian Vol 4 No 2 (2022): JURNAL PENELITIAN
Publisher : Institut Ilmu Kesehatan Nahdlatul Ulama Tuban

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47710/jp.v4i2.174

Abstract

COVID-19 cases since the beginning of 2020 have experienced a fluctuating increase. This incident is caused by a virus that can attack everyone with a high level of transmission. Characteristics of events in each region may be different. Therefore, knowing the distribution of epidemiology in an area is important to study. The purpose of this study was to determine the epidemiological description based on people, place, and time in the working area of the Umbulharjo I Health Center. This study used an analytical descriptive method with secondary data sources derived from the results of an epidemiological investigation conducted in May – August 2021. The results of this study indicate that the majority of COVID-19 cases in the working area of the Umbulharjo I Health Center are women, aged 26-35 years, with the highest area in Kelurahan 3 which has a higher population density than other areas, and the highest spike in cases occurred in The month of July with the most daily cases occurred on 28-29 June 2021. 
Pemetaan Daerah Reseptif Vektor Malaria di Kabupaten Kulon Progo : Mapping Malaria Vektor Receptive Areas in Kulon Progo Regency Elia, Tasya; Astuti, Fardhiasih Dwi; Sukamto, Ali
Aspirator Vol 15 No 1 (2024): Jurnal Aspirator Volume 15 Nomor 1 2024
Publisher : Perkumpulan Entomologi Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58623/aspirator.v15i1.75

Abstract

Malaria is a re-emerging disease. According to the Ministry of Health, malaria cases in Indonesia are second only after India in Southeast Asia. The Special Region of Yogyakarta is one of the cities with the most malaria endemic, precisely in Kulon Progo Regency. Malaria cases in Kulon Progo Regency are experiencing fluency. Kulon Progo Regency itself received a malaria elimination certificate in 2022. Maintenance of malaria elimination can be done by knowing the mapping of malaria vector receptive areas. This study aims to determine the type of Anopheles mosquito larval habitat, determine the coordinates of Anopheles mosquito larval habitat, determine the Anopheles mosquito larval habitat index, and determine the mapping of malaria vector receptive areas in Kulon Progo Regency. The quantitative descriptive research method used spatial analysis with malaria vector receptive areas mapping in Kulon Progo Regency. Inclusion criteria were villages surveyed for malaria mosquito larvae in the mosquito vector survey activities carried out by the Kulon Progo Regency Health Office and Puskesmas in Kulon Progo Regency in 2023. The habitats found in Kulon Progo Regency are rivers, neighborhoods around houses, irrigation, ponds, rice fields, and lagoons, with the most positive habitats in rivers at 35%. Coordinate points are drawn according to the type of habitat found. The highest Anopheles mosquito larval habitat index in Kulon Progo Regency is Kalirejo Village, with a habitat index of 74%, and there are 19 malaria vector receptive villages based on the Anopheles mosquito larval habitat index. The mapping of receptive areas can be used as a reference formalaria prevention and control efforts in the Kulon Progo Regency.
Health-seeking behavior in dengue hemorrhagic fever in Primary Health Care Astuti, Fardhiasih Dwi; Artanti, Galuh; Rokhmayanti, Rokhmayanti; Hastuti, Siti Kurnia Widi
Jurnal Cakrawala Promkes Vol. 7 No. 2 (2025): August
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jcp.v7i2.13955

Abstract

Dengue hemorrhagic fever poses a significant public health challenge in tropical and subtropical regions. In 2022, Bantul Regency recorded 957 cases of dengue fever. This study aims to describe the practices and factors that influence health-seeking behavior among people at the Kasihan I Community Health Center in Bantul Regency. Method: This study employs a descriptive quantitative approach. The data were analyzed both descriptively and quantitatively, and the results are presented in percentage form. Results: 52.6% of respondents visited a doctor when symptoms appeared. Sixty-nine point three percent of respondents believed the fever symptoms they were experiencing were due to the common cold. 94% of respondents visited a doctor when they had dengue fever. 37.8% of respondents visited a health facility on the day they first experienced symptoms. 60.4% of respondents visited the health center most often. 61.7% of respondents had a blood test on the third day after the fever appeared. 71.1% of respondents had sufficient knowledge about dengue fever. 77.9% of respondents had a fair attitude towards dengue fever. 93% of respondents rated the availability of health services as available. 90.1% of respondents considered the cost and distance of health services to be affordable. 92.4% of respondents rated access to health services as easy. Conclusion: Most respondents consulted a doctor for dengue fever symptoms, often mistaking them for a cold. They primarily visited primary healthcare facilities, with blood tests usually done on the third day of fever. Overall, respondents had adequate knowledge and positive attitudes about dengue, along with good access to affordable healthcare services.
Penggunaan Insektisida Rumah Tangga dan Kerentanan Aedes sp. terhadap Permetrin di Kelurahan Sorosutan Kota Yogyakarta: e Use of Household Insecticides and Susceptibility of Aedes sp. against Permethrin in Sorosutan Yogyakarta Azka, Arlina; Astuti, Fardhiasih Dwi
Aspirator Vol 13 No 2 (2021): Jurnal Aspirator Volume 13 Nomor 2 2021
Publisher : Perkumpulan Entomologi Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/asp.v13i2.4798

Abstract

Abstract. The use of household insecticides is an alternative solution to prevent mosquito bites. Most of the household insecticides sold in Indonesia have pyrethroid active ingredients, permethrin, which is available in the aerosol formulation. Inappropriate use of household insecticides can reduce mosquito susceptibility. The objectives of this study are to describe the use of household insecticides and susceptibility of Aedes sp. against permethrin in Sorosutan Yogyakarta. This study used a crosssectional survey design. This study was conducted in December 2018–April 2019 in 354 households in Sorosutan which were randomly selected based on proportional sampling. Interviews about the household insecticides were conducted with the owner or resident of the house. The susceptibility tests used impregnated paper with permethrin 0.75%. The survey results showed that 25.14% of the houses use household insecticides. The insecticide used were aerosol, electric mosquito repellents, and mosquito coils containing active ingredients of the pyrethroid group, namely dimefluthrin, transfluthrin, prallethrin, cypermethrin, and metofluthrin. The susceptibility test results showed a decrease in mosquito susceptibility where the population of Aedes sp. in Sorosutan has been resistant against permethrin. The continuous use of insecticides with pyrethroid active ingredients can develop mosquito resistance against permethrin because all pyrethroids have the same mode of action. This study concludes that only a small proportion (25,14%) of the households used insecticides with the active ingredients used mainly in the pyrethroid group (dimefluthrin, transfluthrin, prallethrin, cypermethrin, and metofluthrin) and the population of Aedes sp. in Sorosutan has been resistant to permethrin. Abstrak. Penggunaan insektisida rumah tangga merupakan solusi alternatif mencegah gigitan nyamuk. Insektisida rumah tangga yang dijual di Indonesia sebagian besar berbahan aktif piretroid, salah satunya permetrin yang tersedia dalam formulasi aerosol. Penggunaan insektisida rumah tangga tidak sesuai anjuran dapat menurunkan kerentanan nyamuk. Tujuan dari penelitian ini adalah mengetahui gambaran penggunaan insektisida rumah tangga dan kerentanan Aedes sp. terhadap permetrin di Kelurahan SorosutanKota Yogyakarta. Penelitian ini menggunakan desain cross-sectional survey. Penelitian dilaksanakan pada bulan Desember 2018–April 2019 di 354 rumah di Kelurahan Sorosutan yang dipilih secara acak berdasarkan proportional sampling. Wawancara tentang penggunaan insektisida rumah tangga dilakukan pada pemilik atau penghuni rumah. Pengujian status kerentanan menggunakan impregnated paper berbahan aktif permetrin 0,75%. Berdasarkan hasil survei, sebanyak 25,14% rumah menggunakan insektisida rumah tangga. Insektisida yang digunakan dari formulasi aerosol, elektrik, dan bakar dengan kandungan bahan aktif golongan piretroid yaitu dimeflutrin, transflutrin, praletrin, sipermetrin, dan metoflutrin. Hasil uji kerentanan menunjukkan telah terjadi penurunan kerentanan, populasi Aedes sp. di Sorosutan ditemukan resisten terhadap permetrin. Penggunaan insektisida berbahanaktif piretroid secara terus-menerus dapat meningkatkan perkembangan resistensi nyamuk terhadap permetrin karena cara kerja insektisida golongan piretroid sama. Kesimpulan dari penelitian ini adalah hanya sebagian kecil (25,14%) rumah tangga yang menggunakan insektisida namun bahan aktif yang digunakan sebagian besar termasuk golongan piretroid (dimeflutrin, transflutrin, praletrin, sipermetrin, dan metoflutrin) dan ditemukan bahwa populasi Aedes sp. di Sorosutan telah resisten terhadap permetrin.
Co-Authors Achmad Arman Subijanto, Achmad Arman Agil Dwi Prasetya Ahmad Fadly Aini, Fitha NurIzza Qurratul Ajeng Puspa Aeni Alghozi, Umar Faruq Annisa Sani Arif Sujagat Arifiani, Ezra Sabrina Arlina Azka Artanti, Galuh Asep Rustiawan Aulia Putri Nugraheni Azzahra, Losa Rarafatmi Badri, Mohammad Zain Desi Nurfita DEWI FITRIANI Dwi Utami Dyah Suryani Eka Irma Saputri Elia, Tasya Erni Gustiina Eti Poncorini Pamungkasari Eva Muslimawati Saputri Farzanah, Atikah Fatimah, Bunga Fikri, Muhammad Ali Hastuti, Siti Kurnia Widi Hasuti, Siti Kurnia Widi Heriyanto Putri, Rona Hafida Heriyanto, M. Junaidy Heriyanto, Moch Junaidy Ike Lukita Padmawati Indriyani, Mila Melinda Khairani Fauziah Liena Sofiana Maretalinia, Maretalinia Marsiana Wibowo Martha Atik Martsiningsih Martini, Titim Martsiningsih, Marta Atik Menik Kasiyati Muamar Afdhal Mahendra Muji Rahayu Muji Rahayu Musyafaah, Novita Siti Nisrina Zahira Haqi Nurfitriyani, Nurfitriyani Nurul Qamariyah Padmawati, Ike Lukita Pradisa Ryan Sukmatama Prasetya, Agil Dwi Pratiwi, Aulia Rahmadina Prisilla Maya Heni Pratiwi Puteri, Amelia Nurhaliza Putri Arum Sholekhati Putri, Rachma Greta Perdana Qurry Amanda Qurry Amanda Izhati Ramadhani Wahyuningtyas Rena Anjeli Wibowo Rokhmayanti , Rokhmayanti Rokhmayanti Rokhmayanti Rokhmayanti, Rokhmayanti Sani, Annisa Saputri, Eva Muslimawati Selly Aprianda Syah Putri Septian Emma Dwi Jatmika Sistiyono Sistiyono, Sistiyono Siti Kurnia Widi Hastuti Suci Musvita Ayu Sufiati Bintanah Sujagat, Arif Sukamto, Ali Sukirto, Novi Wijayanti Sulistyawati Sulistyawati Sulistyowati, Taurina Fitriya Sulistyowati, Taurina Fitriya Sunarti Suyana Suyana Suyana Suyana, Suyana Suyitno Suyitno Sya’baniah, Putri Rahayu Taurina Fitriya Sulistyowati Titim Martini Titim Martini Tri Ratnaningsih Trisasri, Ruri Ullya Rahmawati ULLYA RAHMAWATI Utami, Budi Barata Kusuma Vitri Widyaningsih Wahyu Widyaningsih Wardani, Siska Wati, Erlin Susilo Waya Cahmawati Wibowo, Rena Anjeli Widea Rossi Desvita Wulandari, Ira Pebri Yulianto, Aris Yuniar Wardani