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KONVERSI KITIN MENJADI GLUKOSAMIN PADA PREPUPA MAGGOT (Hermetia illucens) SEBAGAI ALTERNATIF TERAPI SINDROM METABOLIK: NARRATIVE REVIEW Pamungkas, Pandu; Mubinan, Muhammad Fathan; Cahyadi, Achmad; Husnawati, Husnawati
Indonesian Journal of Pure and Applied Chemistry Vol 8, No 1 (2025)
Publisher : Tanjungpura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/indonesian.v8i1.90282

Abstract

Maggots or larvae of the Black Soldier Fly (BSF) are decomposer insects widely cultivated in Indonesia due to their efficient and environmentally friendly ability to degrade organic waste. One of the key components in BSF is chitin, which accounts for approximately 17.93% (w/w) of its total body weight. Chitin can be converted into chitosan through deacetylation and hydrolyzed into glucosamine. Glucosamine has been shown to possess potential in the prevention and management of metabolic syndrome-related diseases such as hypercholesterolemia, diabetes, and obesity. This study explores the potential of glucosamine derived from BSF chitin in reducing the risk of metabolic syndrome. The method used is a literature review of various scientific articles. The findings indicate that glucosamine can activate the AMP-activated protein kinase (AMPK) pathway, which regulates glucose and lipid metabolism. AMPK activation inhibits adipogenesis, fatty acid synthesis, cholesterol production, and adipose tissue formation, positively affecting metabolic syndrome management. Therefore, glucosamine derived from BSF chitin has the potential to serve as a natural bioactive agent for the prevention of metabolic syndrome through AMPK pathway regulation.
Case Report: Analysis of Drug Related Problems (DRP's) in Patients with Hepatic Cirrhosis PNSD Ctp B, Chronic Hepatitis B, Dyspepsia Syndrome, Hypoalbuminemia and Hepatic Function Disorders Husnawati, Husnawati; Aradziluna, Dian; Bidriah, Mutia
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i3.1582

Abstract

Background: Liver cirrhosis is a chronic liver disease characterized by fibrosis and replacement of normal liver tissue with abnormal nodules. The main etiologies include hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, alcohol-related liver disease, and non-alcoholic fatty liver disease (NAFLD). The prevalence of liver cirrhosis based on autopsy findings is around 2.4% in Western countries, while in the United States it is estimated at 360 per 100,000 population, causing approximately 35,000 deaths annually. Objective: This case report aims to describe the treatment and identify drug-related problems (DRPs) in a patient diagnosed with PNSD CTP B liver cirrhosis, chronic hepatitis B, dyspepsia syndrome, hypoalbuminemia, and impaired liver function. Method: This study employed a case report design with primary data obtained from patient interviews and retrospective documentation review. Data were analyzed using the SOAP method to identify DRPs. Results: The analysis revealed minor drug interactions, including spironolactone–furosemide, tenofovir disoproxil fumarate (TDF)–morphine sulfate tablet (MST), and cefixime–furosemide. Conclusion: Patients with complex comorbidities are at increased risk of DRPs. Continuous pharmacotherapy monitoring is essential to minimize toxicity and adverse effects.
Identification of Learning Independence Levels and Its Corelationship with Students Chemical Learning Outcomes at Covid-19 Era Husnawati, Husnawati; Loka, I Nyoman; Sofia, Baiq Fara Dwirani; Anwar, Yunita Arian Sani
AMPLITUDO : Journal of Science and Technology Innovation Vol. 4 No. 2 (2025): August
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/amplitudo.v4i2.310

Abstract

The purpose of this research was to determine the level of independence learning, chemical learning outcomes and the correlation between independence learning and chemical learning outcomes during the Covid-19 period in class XI MIPA SMAN 6 Mataram in 2020/2021. This type of research is called correlational research. The population used was all students from class XI MIPA SMAN 6 Mataram in 2020/2021, which consisted of 4 classes totaling 126 students and the sample used was 56 students using the Slovin formula. The sampling technique is proportional random sampling. Data in the form of the level of independence learning were collected using a questionnaire distribution technique, while the learning outcomes data were collected using a documentation technique from the value of chemistry test result. The data analysis technique used is non-parametric statistics using contingency correlation coefficient test. The results showed that the level of independence learning and chemical learning outcomes were categorized as moderate. The results also show a contingency correlation coefficient (C) which is 0.612 and compared to a rtable of 0.266 which shows there is a positive and significant relationship between independence learning and chemical learning outcomes during the Covid-19 period in class XI MIPA SMAN 6 Mataram Years 2020/2021
Edukasi dan Penyuluhan Diabetes Mellitus Kepada Masyarakat Desa Empat Balai Kecamatan Kuok Kabupaten Kampar Riau Husnawati, Husnawati; Susanty, Adriani; Sari, Seftika; Thamrin, Thamrin; Suheri, Wira Noviana; Izrawati, Izrawati; Delvi, Kasma Muria; Dirmaningsih, Septi; Ngazizah, Yeti Nur; Meridona, Meridona; Sandi, Widya Ari
QISTINA: Jurnal Multidisiplin Indonesia Vol 4, No 1 (2025): June 2025
Publisher : CV. Rayyan Dwi Bharata

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57235/qistina.v4i1.6566

Abstract

Diabetes Mellitus (DM) is a non-communicable disease with increasing prevalence, particularly in rural areas with limited access to health information and services. This community service activity aimed to improve the knowledge of residents in Empat Balai Village, Kuok Subdistrict, Kampar Regency, Riau, regarding DM, its risk factors, and prevention efforts through an educational and participatory community-based approach. The method involved direct counseling, group discussions, and pre-test and post-test assessments to evaluate participants' understanding. The results indicated a significant improvement in knowledge, with the average score increasing from 6.7 (pre-test) to 8.98 (post-test). The education program successfully dispelled common myths, raised awareness of healthy lifestyles, and fostered positive perceptions of both medical and non-medical treatment options. The enthusiastic response from the community demonstrated the effectiveness of this approach in promoting health and preventing non-communicable diseases. This activity highlights the importance of collaboration between students, healthcare workers, and local authorities in public health education and the need for sustained outreach programs.
Pengaruh Sosial Ekonomi Orang Tua, Perilaku Keuangan dikeluarga, dan Kontrol Diri terhadap Manajemen Keuangan Pribadi Mahasiswa di Kabupaten Sinjai S, Rusnawati; Husnawati, Husnawati
Study of Scientific and Behavioral Management Vol 2 No 3 (2021)
Publisher : Universitas Islam Negeri Alauddin Makassar, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/ssbm.v2i3.23896

Abstract

Tujuan dari penelitian ini yaitu untuk mengetahui pengaruh sosial ekonomi orang tua, perilaku keuangan di keluarga, dan kontrol diri terhadap manajemen keuangan pribadi mahasiswa di Kabupaten Sinjai. Jenis penelitian yang digunakan adalah Metode Kuantitatif. Sampel dalam penelitian ini sebanyak 158 responden dengan menggunakan Tekhnik Sampling Incidental. Jenis data yang digunakan yaitu data primer dan data sekunder, Adapun teknik analisis data yang digunakan dalam penelitian ini yaitu uji asumsi klasik, pengujian hipotesis, dan analisis regresi linear berganda. Dari hasil penelitian yang dilakuakan dapat disimpulkan bahwa terdapat pengaruh antara sosial ekonomi orang tua, perilaku keuangan di keluarga dan kontrol diri (uji secara simultan) terhadap manajemen keuangan pribadi mahasiswa di Kabupaten Sinjai, terdapat pengaruh sosial ekonomi orang tua (uji secara parsial) terhadap manajemen keuangan pribadi mahasiswa di Kabupaten Sinjai, terdapat pengaruh perilaku keuangan di keluarga (uji ecara parsial) terhadap manajemen keuangan pribadi mahasiswa di Kabupaten Sinjai, dan terdapat pengaruh kontrol diri (uji secara parsial) terhadap manajemen keuangan pribadi mahasiswa di Kabupaten Sinjai. Kata Kunci: Sosial Ekonomi Orang Tua, Perilaku Keuangan di Keluarga, Kontrol Diri dan Manajemen Keuangan Pribadi. ABSTRACTThe purpose of this study was to determine the influence of parents' socioeconomic, financial behavior in the family, and self-control on the personal financial management of students in Sinjai Regency. The type of research used is the Quantitative Method. The sample in this study was 158 respondents using theTechnique Incidental Sampling. The types of data used are primary data and secondary data. The data analysis techniques used in this research are classical assumption test, hypothesis testing, and multiple linear regression analysis. From the results of the research conducted, it can be concluded that there is an influence between parents' socioeconomic, financial behavior in the family and self-control (simultaneous test) on the personal financial management of students in Sinjai Regency, there is a socio-economic influence of parents (partial test) on management students' personal finances in Sinjai Regency, there is an effect of financial behavior in the family (partial test) on the personal financial management of students in Sinjai Regency, and there is an effect of self-control (partial test) on students' personal financial management in Sinjai Regency. Keywords: Parents' Socio-Economic, Financial Behavior in the Family, Self Control and Personal Financial Management.
Pendeteksian Fraud Investasi Obligasi Dana Pensiun Semen Tonasa Husnawati, Husnawati; Binti Asrul, Andriany; Annisa Zahidah, Nur; Auliya Iskandar, Firda; Maidin, Zulkifli
Center of Economic Students Journal Vol. 5 No. 1 (2022): January-Maret (2022)
Publisher : Fakultas Ekonomi dan Bisnis, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (227.065 KB) | DOI: 10.56750/csej.v5i1.45

Abstract

Penelitian ini bertujuan untuk mengetahui dan menganalisis penerapan strategi pendeteksian fraud pada investasi obligasi Dana Pensiun Semen Tonasa. Pendeteksian fraud menjadi upaya dalam menghadapi kecurangan (fraud) yang dapat terjadi setiap saat kapan saja dan di mana saja pada perusahaan khususnya juga untuk investasi dari Dana Pensiun Semen Tonasa. Penelitian ini merupakan penelitian kualitatif dengan menggunakan data primer yang diperoleh melalui teknik pengumpulan data berupa interview (wawancara) pada narasumber selaku pengelola investasi Dana pensiun Semen Tonasa. Hasil penelitian menunjukkan bahwa Dana Pensiun Semen Tonasa telah menerapkan strategi pendeteksian fraud yang baik untuk menjaga integritas industri agar selalu tetap bersih melalui identifikasi gejala fraud secara dini, melakukan mitigasi risiko atas investasi obligasi tersebut.
The Preservation of Yogyakarta’s Cultural Heritage Through a Training Program in The Appropriate Utilization of Traditional Javanese Attire Sa'diyah, Devi Merina Tuz; Sekti, Marita Nur; Husnawati, Husnawati; Ramadlani, Afra Shafa; Septi, Lia Eka
KOLOKIUM Jurnal Pendidikan Luar Sekolah Vol 13, No 2 (2025): Kolokium: Publishing October 2025
Publisher : Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/kolokium.v13i2.1176

Abstract

Gagrak Yogyakarta is a traditional Javanese attire in the Yogyakarta style that is rich in meaning in each of its components. It is imperative for the younger generation to acquire knowledge of the various components and meanings of traditional culture to ensure its preservation in the face of the increasingly massive cultural shifts that are occurring. The study was carried out in Yogyakarta, and it involved cultural experts. It utilized a qualitative research method with a case study design. Non-formal education is important in preserving culture, especially through training program that pass on local values, skills and traditions. The training program prioritizes skills based on local resources, in this case related to the provisions of the use of regional traditional attire called Gagrak Yogyakarta. The implementation of this training program furnishes the community with a comprehensive learning platform that meticulously examines the semantics and utilization of each component in Gagrak Yogyakarta. This training program was implemented as a component of the broader initiative aimed at safeguarding the cultural heritage of Yogyakarta, with a particular focus on the proper utilization of Yogyakarta’s traditional attire.
Knowledge and Attitude of Hypertension Patients towards Traditional Medicines: A Cross-sectional Study at Public Health Center, Siak, Riau Husnawati, Husnawati; Dewi, Ratna Sari; Ningsih, Yozi Fiedya; Fitriani, Dewi
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.280-285.2023

Abstract

Hypertension is a significant global concern associated with severe cardiovascular ailments, including stroke, myocardial infarction, cardiac insufficiency, and renal dysfunction. Traditional medicines (TM) represent a potential alternative treatment modality for the management of hypertension. Hence, this study aims to establish the relationship between individuals' knowledge and attitudes about using TM among hypertension patients. This observational research utilizes a descriptive-analytic approach with a cross-sectional design. Validated questionnaires were used to collect the knowledge and attitudes data of respondents. The correlation between knowledge and attitudes was analyzed with the Spearman test using SPSS version 24. A total of 102 respondents were successfully acquired using purposive non-probability sampling. The results of this study indicate a significant statistical relationship between the knowledge and attitudes of hypertensive patients regarding the utilization of TM (p-value 0.000). Furthermore, a moderate positive correlation (rs 0.493) was observed, suggesting that an improvement in knowledge is associated with a corresponding enhancement in the attitude of hypertensive patients towards TM.
PROFIL PEMAKAIAN ANTIBIOTIK PROFILAKSIS PADA PASIEN BEDAH ORTHOPEDI DI PEKANBARU MEDICAL CENTER Fitri, Aulia; Husnawati, Husnawati
Usadha Journal of Pharmacy Vol. 3 No. 2 (2024): Mei
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/ujp.v3i2.322

Abstract

Dalam bidang bedah, antibiotik profilaksis merupakan antibiotik yang diberikan sebelum, saat dan hingga 24 jam pasca operasi dengan tujuan untuk mencegah terjadinya infeksi luka operasi. Penelitian ini bertujuan untuk melihat gambaran penggunaan antibiotik profilaksis dalam mencegah terjadinya infeksi pasca bedah orthopedi di rumah sakit Pekanbaru Medical Center(PMC). Jenis penelitian yang dilakukan adalah observasional dengan studi deskriptif menggunakan data retrospektif, dengan teknik purposive sampling terhadap 41 data rekam medik yang memenuhi kriteria inklusi. Hasil penelitian menunjukkan bahwa penggunaan antibiotik yang paling banyak digunakan adalah kombinasi cefazolin 44,11% dan amikasin 32,35%. Hanya 25% pasien yang menerima antibiotik profilaksis tepat waktu pemberian 2-0 jam sebelum operasi.
Analysis of Cold Chain Product Management in Community Health Centers in Siak Regency Based on Their Accreditation Level Putri, Monica Rifa; Husnawati, Husnawati; Sari , Seftika
Jurnal Indonesia Sosial Sains Vol. 6 No. 9 (2025): Jurnal Indonesia Sosial Sains
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jiss.v6i9.1897

Abstract

This study aims to analyze the management of cold chain products in primary health centers (Puskesmas) across Siak Regency based on their accreditation levels. The research is motivated by the high rate of cold chain management deviations that may compromise the quality and effectiveness of medicines, particularly vaccines. A mixed-method approach with a sequential explanatory model was applied, involving all 16 Puskesmas as the total sample. Quantitative data were collected through observations using the 2020 CDOB checklist, while qualitative data were obtained from in-depth interviews with cold chain officers. Data analysis employed the Chi-Square test to examine the relationship between accreditation levels and cold chain management quality. The results revealed a significant relationship between accreditation status and management quality, especially in facility compliance, SOP adherence, maintenance, and calibration standards. Highly accredited Puskesmas (paripurna and utama) demonstrated “good” to “very good” management performance, whereas non-accredited facilities remained in the “fair” category or lower. These findings highlight accreditation as a key determinant of effective cold chain management. The study underscores the need for continuous training, improved infrastructure, and enhanced monitoring systems to ensure the quality of cold chain medicines in primary health services.
Co-Authors Adriani Susanty Afra Shafa Ramadlani Agrina, Agrina Agustina, Sasa Aini Nurul Aisyah Putri, Aisyah Aminullah, Muh. Andriani, Dita Maulida Anggraeni, Ica Winanda Anggraini, Laurentin Leni Annisa Zahidah, Nur Aradziluna, Dian Asmawiyah Asmawiyah Aulia Fitri, Aulia Auliya Iskandar, Firda Aulyah Zakilah Ifani Azizah, Nurholik Baehaqi Bidriah, Mutia Binti Asrul, Andriany Cahyadi, Achmad Delvi, Kasma Muria Dewi Anggraeni DEWI FITRIANI Diah Ayu Gustiningsih Dirmaningsih, Septi Djaswadi Dasuki Ermatita - Erna Budiarti Fadillah, Ma'isyatul Fatmalia, Anggun Febriana, Kikan Fina Aryani, Fina Haiyul Fadhli Harianto Harianto Hasnah Hasnah Hidayatullah, Bagus Ananta Humam, Faris I Nyoman loka Ika Yuni Astutik, Ika Yuni Imran D, Reza Iriani, Revy Isdarmanto, Isdarmanto Italiana, Fifi Izrawati, Izrawati Juwaidin, Juwaidin Khairani, Putri Laia, Cindy Oktaviana LAKSMI AMBARSARI Lilianti, Mita Ayu Maidin, Zulkifli Mardiana Mardiana Massikki, Massikki Mauizdati, Nida Meridona, Meridona Miftahul Jannah Mubarokah, Syahratul Mubinan, Muhammad Fathan Muh. Haris Zubaidillah Muhamad Amin Muharramah, Ulfah Mukhtar, Afiah Musyarapah, Musyarapah Mutia Liasari, Mutia Nafisy, Yera Nanda Nanda Neni Frimayanti Ngazizah, Yeti Nur Ningsih, Yozi Fiedya Nurdiansa, Eko Saputra Nurdin, Gaby Maulidya Nurjaya Gani Nurul fadillah, Nurul Pinandari, Anggriyani W. Pratiwi, Erniza Putri, Monica Rifa Rahmi, Helvy Rasihen, Sri Lidya Ratih Damayanti Ratna Sari Dewi Rendyansyah Reni Zulfitri Retnosari Andrajati Rian Rahmanda Putra Ricardo, Nadira Atiqah Richa Afrianti, Richa Rina Zahara Rinaldi, Ahmad Rizki, Famella Yustika Rossi Passarella Ruska, Shinta Liana Rusnedy, Rahmayati S, Rusnawati S.Intam, Rezki Nurul Jariah Sa'diyah, Devi Merina Tuz Sainab Sakinah, Rezkila Sandi, Widya Ari Sarbini Sarbini, Sarbini Sari, Rinita Sastrawati, Atriwida Sekti, Marita Nur Septi Muharni Septi, Lia Eka Sinaga, Giacinta Gracesandy Sinulinga, Yori Yunita Siregar, Lisa Andriyani Siswanto Agus Wilopo Sitanggang, Sarah Dianora Sofia, Baiq Fara Dwirani Sri Watini Subagya, Billy Sutarno Sutarno Syafitri, Yellia Syair, Andi Irfandi Tahir, Muh Syarif Teuku Zulkarnain Thamrin Thamrin Triawan, Muhammad Agus Untarti, Dade Prat Verano, Dwi Asa Wahyudi Wahyudi Wahyuni, Maulidia Wanty, Fitri Prima Wira Noviana, Wira Noviana YUNITA ARIAN SANI ANWAR Yunita Fauzia Achmad Zariyatul, Zariyatul