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The potential of betle leaf (Piper betle L.) against Staphylococcus aureus to cure mastitis: A systematic review Jannata, Rahma Winahyu; Prihantono, Prihantono; Idris, Irfan
Babali Nursing Research Vol. 4 No. 3 (2023): July
Publisher : Babali Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37363/bnr.2023.43269

Abstract

Mastitis is a problem in breastfeeding causes nutritional deficiencies in the baby. Staphylococcus aureus is one of the bacteria that causes mastitis. Betle leaf (Piper betle L.) has been used in several health problems and has antimicrobial activity. This study aims to explore the potential of betel leaf (Piper betle l.) against Staphylococcus aureus to cure mastitis. A systematic review was carried out according to the PRISMA guidelines. Searches were conducted in three databases namely PubMed, Google Scholar, and Science Direct. Search using keywords according to the Mesh term, namely 'betle leaf (Piper betle l.)', 'Staphylococcus aureus' and 'Mastitis'. 198 articles were found in a database search. 8 studies were analyzed. All studies found that both types of pipers betle, both green and red, showed positive effects in the treatment of mastitis. Processing techniques, storage, and certain concentrations such as boiling temperature affect the optimum inhibition zone of bacteria. The addition of certain formulas also increases the antimicrobial activity. The use of antibiotics and betel leaf extract can be used simultaneously to treat mastitis. Betle leaf (Piper betle L.), has a positive effect on the management of mastitis, but processing techniques, concentrations, and adjuvants need to be studied further.
The Effect of Sterilization on Vitamin D Levels in Male and Female Rats Pratiwi, Hamria; Idris, Irfan; Sari, Dwi Kesuma
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 6 No.1, JANUARY 2022
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Sterilization is an operation that can prevent reproduction and is useful as a treatment. Sterilization is done by removing the reproductive organs, in males it is called orchiectomy and in females it is called ovariohysterectomy which causes a decrease in the production of reproductive hormones. Previous studies have proven a physiologic relationship between reproductive hormones and vitamin D activation, but there is no information on the effect of sterilization on vitamin D levels. This study aimed to determine the effect of sterilization on vitamin D levels. This study was experimental with a Posttest-Only Control Group design. design. A total of 24 wistar rats consisting of 12 male rats and 12 female rats and each were divided into two groups, 6 female rats sterilized (ovariohysterectomy), 6 female rats non-sterilized, 6 male rats sterilized (orchiectomy) and 6 male rats non-sterilized. -sterilization. Wistar rats that were 10 weeks old were transferred to their respective cages and given regular feed to all groups of rats for 7 days as an adaptation process, after which sterilization was carried out in the sterilization group. After 6 weeks post-treatment, the rats were 17 weeks old and then blood was taken for examination of Vitamin D levels using the elisa method which was carried out at Hum-Rc Hasanuddin University Hospital. The results showed that the mean value of vitamin D levels in the ovariohysterectomy group was lower than in the non-sterilized group and was significant (Mann-Withney, p<0.05). The orchiectomy group was also lower than in the non-sterlized group and not significant (Independent T test, p> 0.05). It can be concluded that sterilization can reduce vitamin D levels in pets. Keywords: Sterilization, Ovariohysterectomy, Orchiectomy, and Vitamin D
Pengaruh Pemberian Minuman Sopi Mayang Beralkohol terhadap Jumlah Spermatozoid, Pada Tikus Putih (Rattus norvegicus) Jantan Sanaky, Marliyati; Idris, Irfan; Rafiah, Siti; Arsyad, Aryadi
MAHESA : Malahayati Health Student Journal Vol 4, No 11 (2024): Volume 4 Nomor 11 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i11.15041

Abstract

ABSTRACT The alcoholic Sopi drink comes from palm trees (Arenga pinnata MERR), a type of palm tree spread throughout almost all of Indonesia. The alcohol in the traditional Sopi drink is ethanol (CH3CH2-OH) from fermented sap. This study aimed to examine the effect of Sopi Mayang drink on the increase in cytochrome P450 mRNA expression, increase in CYP2E1 protein levels and decrease in the number of spermatozoids using male white rats. This research is laboratory experimental, using the Randomized Post-test Only Control Group Design. Giving Sopi Mayang with a dose of 2.7 ml decreased the number of spermatozoids, namely 33,815,000, compared to the control group without giving Sopi Mayang, namely 56,680,000 (p = 0.0001). Sopi Mayang, with a dose of 4.05 ml, decreased sperm count from 33,815,000 to 22,334,775 (p= 0.0001). Sopi Mayang, with a dose of 5.4 ml, decreased sperm count from 22,865,000 to 18,250,309 (p=0.0001). There was a decrease in the number of spermatozoids in mice given Sopi Mayang. Keywords: Alcohol, Sopi Mayang, Spermatozoid, white rats ABSTRAK Minuman Sopi beralkohol berasal dari  pohon Enau/Aren (Arenga pinnata MERR) termasuk salah satu jenis tanaman palma, yang tersebar hampir di seluruh wilayah Indonesia. Alkohol yang terkandung dalam minuman tradisional Sopi adalah etanol (CH2CH3-OH) dari fermentasi nira. Penelitian ini ditujukan untuk melihat pengaruh minuman Sopi Mayang terhadap jumlah peningkatan ekspresi mRNA sitokrom P450, peningkatan kadar protein CYP2E1dan penurunan jumlah spermatozoid dengan menggunakan tikus putih jantan. Penelitian ini adalah eksperimental laboratoris, dengan menggunakan rancangan The Randomized Post-test Only Control Group Design. Pemberian Sopi Mayang dengan dosis 2,7 ml terjadi penurunan jumlah spermatozoid yaitu 33.815.000  dibandingkan dengan kelompok kontrol  tanpa pemberian  Sopi Mayang yaitu 56.680.000 (p = 0,0001). Sopi Mayang dengan dosis 4,05 ml terjadi penurunan jumlah sperma dari 33.815.000 menjadi 22.334.775 (p= 0,0001).  Sopi Mayang dengan dosis 5,4 ml terjadi penurunan jumlah sperma dari 22.865.000 menjadi 18.250.309 (p=0,0001). Terjadi penurunan jumlah spermatozoid, pada tikus yang diberikan Sopi Mayang. Kata Kunci: Alkohol, Sopi Mayang, Spermatozoid, Tikus Putih
PENGARUH ELASTIC BAND EXERCISE TERHADAP RSIIKO JATUH DAN KEKUATAN OTOT TUNGKAI PADA LANSIA DI LEMBAGA KESEJAHTERAAN SOSIAL LANJUT USIA BATARA HATI MULIA KABUPATEN GOWA Nindrahayu, Nindrahayu; Ariyandy, Andi; Idris, Irfan; Abadullah, Meutiah Mutmainnah; Arbaim Hasyar , Andi Rizky
Media Bina Ilmiah Vol. 18 No. 3: October 2023
Publisher : LPSDI Bina Patria

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33758/mbi.v18i3.470

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh elastic band exercise terhadap risiko jatuh dan kekuatan otot tungkai pada lansia dengan desain quasi eksperimental one group pretest-posttest. Responden dalam penelitian ini berjumlah 21 orang yang akan diberikan intervensi berupa elastic band exercise. Sebelum diberikan intervensi, dilakukan pretest berupa TUG tes untuk menilai skor risiko jatuh dan 30SCS untuk menilai kekuatan otot tungkai pada lansia. Post test dilakukan setelah diberi intervensi 3 kali seminggu selama 5 minggu. Uji Wilcoxon digunakan untuk mengetahui perubahan sebelum dan sesudah pemberian latihan. Hasil penelitian menunjukkan ada penurunan skor risiko jatuh dan peningkatan kekuatan otot tungkai pada responden dengan nilai p=0,000. Skor risiko jatuh mengalami perbaikan dari 15±(11-19) menjadi 10±(9-13), sedangkan kekuatan otot tungkai mengalami peningkatan dari 8±(5-10) menjadi 12±(9-14). Elastic band exercise efektif dalam menurunkan risiko jatuh dan meningkatkan kekuatan otot tungkai pada lansia
Health-Promotion Approaches to Postpartum Hypertension: Systematic Review of Causes and Management in Maternal Health Rauf, Efri Leny; Chalid, St. Maisuri T.; Idris, Irfan; As’ad, Suryani; Jayanti, Ira
Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Vol. 8 No. 12: DESEMBER 2025 - Media Publikasi Promosi Kesehatan Indonesia (MPPKI)
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/mppki.v9i1.9120

Abstract

Introduction: Postpartum hypertension remains one of the leading causes of maternal morbidity and mortality worldwide. This condition may persist from gestational hypertension, preeclampsia, or chronic hypertension, and can also develop de novo postpartum. Understanding its etiology, risk factors, and management strategies is essential to improving maternal health outcomes and preventing long-term cardiovascular complications. Methods: This study applied a systematic review design based on the Arksey and O’Malley framework, guided by the PEOS (Population, Exposure, Outcome, Study Design) model. A comprehensive literature search was conducted across PubMed, ScienceDirect, EBSCO, and Google Scholar databases for studies published between 2009 and 2023 using the keywords “postpartum hypertension,” “causes,” and “management.” Out of 120 identified studies, 20 met the inclusion criteria and were critically appraised using the Hawker Quality Assessment tool. Results: Postpartum hypertension is most frequently associated with preeclampsia, chronic hypertension, and gestational hypertension; however, iatrogenic causes such as bromocriptine therapy and excessive sodium intake were also identified. Most women experience a transient rise in blood pressure within the first 5 days postpartum, attributed to increased intravascular volume. The majority of studies emphasized inadequate screening and follow-up during the first week after delivery, with up to one-third of patients remaining untreated. Recent interventions, including digital monitoring systems and eHealth-based self-management, demonstrated improved outcomes in detection and patient adherence. Conclusion: Effective management of postpartum hypertension requires timely diagnosis, structured follow-up, and coordinated transition to primary care for long-term cardiovascular risk reduction. Health-care providers must enhance awareness and clinical competence, as complications from misdiagnosis or undertreatment remain common yet preventable through integrated postpartum surveillance and health-promotion strategies.
Co-Authors Abadullah, Meutiah Mutmainnah Abustani, Muthiah Adnan, Endy Allo, Sarjani Linggi Am, Nasrudin Amran, Muhammad Yunus Amru, Khaeriah Andi Kurnia Bintang, Andi Kurnia Andi Rizky Arbaim Hasyar Arief, Nila Ardilla Arif Santoso Ariyandy, Andi Arsyad, Muhammad Aryadi Asih, Puji BS. As’ad, Suryani Bahar, Ashari Bukhari, Agussalim Dahniarti, Dhany Din Syafruddin Djabir, Yulia Yusrini Djaharuddin, Irawaty Dwi Kesuma Sari Gafur, Rahmi Hadi, Anto J. Halik, Handayani Hammado, Nurussyariah Hasyim, Ammar A. Irawan Yusuf Irma Rahayu, Irma Ismail, Amirah Febrianti Itani, Kei Iyori, Mitsuhiro Jannata, Rahma Winahyu Jayanti, Ira Kasim, Hasim Liong Boy Kurniawan, Liong Boy Mallisa, Hilda Emma Meryana*, A. Kurnia Bintang**, Muh. Akbar**, Susi Aulina**, Yudy Goysal**, Arifin Limoa*** Minarti, Deri Lidya Mulyamin, Winda Nakamura, Kurumi Nindrahayu, Nindrahayu Nurisyah, Sitti Paharu, Kabah Pratiwi, Hamria Prihantono, Prihantono Rafiah, Siti Rambulangi, Samrichard Rauf, Efri Leny RR. Ella Evrita Hestiandari Sanaky, Marliyati Satriana Satriana St. Maisuri T. Chalid Tadjuddin Chalid, Maisuri Tombeg, Zadrak Wardihan Sinrang, Andi Widaningsih, Yuyun Wuysang, Audry Devisanty Yetti R, Erni Yoshida, Shigeto Yustisia, Ika Yusuf Yenni Zainal, Kartika H.