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All Journal Jurnal Ilmiah Farmasi Natural Science: Journal of Science and Technology Pharmaciana: Jurnal Kefarmasian DeKaVe The Journal of Pure and Applied Chemistry Research Jurnal Farmasi Klinik Indonesia Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) MPI (Media Pharmaceutica Indonesiana) Scholaria: Jurnal Pendidikan dan Kebudayaan Jurnal Wiyata : Penelitian Sains dan Kesehatan CARADDE: Jurnal Pengabdian Kepada Masyarakat Jurnal Biomedika dan Kesehatan Abdimasku : Jurnal Pengabdian Masyarakat Berkala Ilmiah Mahasiswa Farmasi Jurnal Farmasi dan Sains Indonesia (JFSI) Journal of Community Practice and Social Welfare (JaCiPS) Media Farmasi Indonesia Sainsbertek Jurnal Ilmiah Sains & Teknologi Prosiding Seminar Nasional Universitas Ma Chung JUKEJ: Jurnal Kesehatan Jompa Jurnal Novem Medika Farmasi Jurnal Farmasi Ma Chung: Sains, Teknologi, dan Klinis Komunitas KOPEMAS Jurnal Ekonomi Kesehatan Indonesia Academia Open
Martanty Aditya, Martanty
Program Studi Farmasi Fakultas Sains Dan Teknologi Universitas Ma Chung
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Efek Kombinasi Ekstrak Kunyit (Curcuma longa L.) dan Asam Jawa (Tamarindus indica) sebagai Antidepressan pada Pengamatan Perilaku Ikan Zebra (Danio rerio) Cesa, Fibe Yulinda; Aditya, Martanty; Fauziah, Mutiara; Weol, Euodia Gloria Friska; Aini, Anisa Nur
Jurnal Ilmiah Farmasi Vol. 22 No. 2 (2026): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol22.iss2.art18

Abstract

Background: Antidepressants are a common treatment for depression, requiring ongoing medication monitoring. Extracts of turmeric (Curcuma longa L.) and tamarind (Tamarindus indica) have shown significant potential as antidepressants due to their respective mechanisms. This study explores how these compounds interact to provide antidepressant effects, specifically using a zebrafish model.Objective: To evaluate the antidepressant effects of turmeric and tamarind extracts in a zebrafish model by observing behavioral changes such as freezing and rapid movement.Method: The Open Field Test (OFT) was used, utilizing the AnimApp application to categorize freezing and rapid movement behaviors in zebrafish. The treatment groups consisted of a negative control, a depression control, a positive control (vitamin B6), and treatment groups with concentrations of 10%, 20%, and 30% of the extract combination. Both vitamin and extract combinations were administered intraperitoneally. Data were analyzed using ANOVA at a 95% confidence level. Results: The positive control group showed the lowest rapid movement (0.1 ± 0.1 m/s), indicating a strong anxiolytic effect, while the 30% extract group exhibited the highest rapid movement (9.8 ± 1.1 m/s), which may reflect increased stress (p < 0.05). The depression control group had the longest freezing duration (24.6 ± 7.3 seconds), whereas all extract treatment groups (10%, 20%, and 30%) demonstrated significant reductions in freezing with durations of 1.1 ± 0.8, 2.1 ± 1.4, and 2.2 ± 2.0 seconds, respectively (p < 0.05). The decrease in freezing time in the extract groups was even lower than the positive control (2.6 ± 0.8 seconds).Conclusion: The combination of tamarind and turmeric extracts demonstrated a significant antidepressant effect in zebrafish at a 10% concentration, with a notable reduction in freezing behavior. However, higher concentrations (20% and 30%) did not enhance this effect and instead triggered an increase in rapid movement activity. This indicates the need for dose optimization to ensure effective and safe use of this extract combination.
Edukasi Kesehatan Mata untuk Pencegahan Gangguan Penglihatan Anak Usia Dini Leny Yuliati; Martanty Aditya; Djoko Irawan; Jesha Imelda Feron
ABDIMASKU : JURNAL PENGABDIAN MASYARAKAT Vol 9, No 3 (2026): SEPTEMBER 2026
Publisher : LPPM UNIVERSITAS DIAN NUSWANTORO

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62411/ja.v9i3.3384

Abstract

Gangguan penglihatan pada anak usia dini perlu dicegah melalui pola asuh dan komunikasi efektif orang tua. Oleh sebab itu, edukasi kepada orang tua perlu dilakukan agar upaya pencegahan tersebut dapat dilakukan. Dalam kegiatan pengabdian kepada masyarakat ini, edukasi kesehatan mata kepada orang tua siswa taman kanak-kanak dilakukan dengan metode presentasi audiovisual. Adapun materi yang dipaparkan diantaranya pola asuh dan komunikasi efektif, rekomendasi pembatasan waktu layar, dan sumber nutrisi yang bermanfaat untuk kesehatan mata. Pengukuran peningkatan pengetahuan peserta dievaluasi berdasarkan skor pre-test dan post-test yang dikerjakan sebelum dan setelah materi edukasi diberikan. Uji t berpasangan menunjukkan peningkatan pengetahuan yang signifikan dari 17 orang peserta. Skor rata-rata pre-test meningkat dari 6,55 menjadi 8,00 (skala 10) setelah edukasi diberikan. Dilakukan evaluasi nilai rata-rata N-gain untuk tiga pertanyaan dengan persentase jawaban salah paling banyak. Didapatkan nilai N-gain sebesar 0,44 (kategori sedang), sehingga metode edukasi ini dinilai cukup efektif meningkatkan pengetahuan orang tua. Walaupun demikian, peningkatan pengetahuan peserta masih belum merata. Sebesar 59% peserta menunjukkan kategori peningkatan pengetahuan sedang ke tinggi, sedangkan 41% peserta lainnya menunjukkan kategori peningkatan pengetahuan rendah.
Co-Authors Aftoni, Muhammad Hilmi agustin, Christina Aini, Anisa Nur Aprilia, Devi Ratna Arif Santoso Cesa, Fibe Yulinda Chresiani Destianita Yoedistira Chresiani Destianita Yoedistira Chresiani Destianita Yoedistira Dewi Fortuna Surat Bala Dion Notario Djoko Irawan Ega Malia Jiska Eva Monica Eva Monica, Eva Fauziah, Mutiara Feliadewi Ruth Feliadewi Ruth Fibe Y. Cesa Fibe Yulinda Cesa Fibe Yulinda Cesa Fibe Yulinda Cesa Fibe Yulinda Cesa Fina Noor Maghfira Godeliva Adriani Hendra Jesha Imelda Feron Kestrilia Rega Prilianti Leny Yuliati Maitreya, Putera Meylinda Widyasari Monica, Eva Muhammad Hilmi Afthoni muliyawan, Johan Nugraha, Dhanang Prawira Nurul Najlatun Nisa Putera Maitreya Putri Devy Septya Ratu, Modestus Reflinda Sindy Puspita Rehmadanta Sitepu Rehmadanta Sitepu Rehmadanta Sitepu Rehmadanta Sitepu Renaldy Kristian Yohansyah ria septiana Rina Setyowati Rinda Puspita Sari Rizal Bing Garumal Indianta Rollando, Rollando Sabrina Handayani Tambun Salsabila Rohadatul Aisy Setiawan, Hendry Sintia Dina Pranata Sitepu, Rehmadanta Sri Susilowati Sri Suwarni Sri Suwarni Suhul Raos Kumawula Ing Gustyas Susanto, FX. Haryanto Tegar Andito Venty Yuliasari Weol, Euodia Gloria Friska Wulandari, A. Ratna Yandriyani, Devilke Yanuar, Michael Resta Surya Yeni Rahmawati Yulis Mitra Reformasika Zita, Hestyana