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All Journal Jurnal Ilmu Kimia Universitas Brawijaya KOVALEN: Jurnal Riset Kimia Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Adi Widya : Jurnal Pengabdian Masyarakat Window of Health : Jurnal Kesehatan CHEESA: Chemical Engineering Research Articles JOPS (Journal Of Pharmacy and Science) Jurnal Surya Masyarakat Klinikal Sains (Jurnal Analis Kesehatan) Surya Abdimas Jurnal Biomedika INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY JPP Jurnal Kesehatan Poltekkes Palembang JURNAL ANALIS LABORATORIUM MEDIK Community Service Journal of Indonesia Jurnal Ilmiah Farmako Bahari Jurnal Riset Kefarmasian Indonesia Medicra (Journal of Medical Laboratory Science/Technology) Jurnal Surya Masyarakat Indonesian Journal of Cultural and Community Development Indonesia Berdaya Borneo Journal Of Pharmascientech Jurnal Mandala Pengabdian Masyarakat Environmental and Toxicology Management (ETM) Jurnal Abdi Masyarakat Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Farmasi Sains dan Praktis SWARNA Journal of Artificial Intelligence and Digital Business Cerdika: Jurnal Ilmiah Indonesia Journal of Pharmacy Science and Technology Jurnal Laboratorium Khatulistiwa Jurnal Pengabdian Kepada Masyarakat Meambo SWARNA: Jurnal Pengabdian Kepada Masyarakat Maslahat
Ersalina Nidianti
Analis Kesehatan, Fakultas Kesehatan, Universitas Nahdlatul Ulama Surabaya
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UJI TOKSISITAS AKUT LD50 CAMPURAN EKSTRAK DAUN BIDARA ARAB (Ziziphus spina-christi L.) dan DAUN SAGA POHON (Adenanthera pavonina) Dinda Enka Nita; Ersalina Nidianti; Khoirul Ngibad; Suprapto Maat; Bismi Aisyah Rahma Putri
Klinikal Sains : Jurnal Analis Kesehatan Vol. 13 No. 1 (2025): Juni
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikalsains.v13i1.5046

Abstract

The mixture of Arabian bidara leaf extract (Ziziphus spina-christi L.) and saga tree leaves (Adenanthera pavonina) is a plant used by the community which is empirically used as a traditional medicine such as hyperlipidemia and hypercholesterolemia. The purpose of mixing these two extracts is to increase the efficacy of both extracts which are rich in antioxidants. However, a study on the acute toxicity test of the use of the mixture of these plants has not been carried out, so an acute toxicity test is needed on both extracts to see the safety of use. The purpose of this study was to determine the symptoms of toxicity and the LD50 value caused after the fusion of 56 male and female Wistar strain white rats (28 males, 28 females) which were then divided into 7 groups. The negative control group was not treated, the carrier control group was given a suspension of 1% Na CMC at a dose of 0 mg/Kg given distilled water and the treatment group was given a mixture of Arabic bidara leaf extract and saga tree leaves 1:1 at a dose of 2000 mg/KgBB, 4000 mg/KgBB, 6000 mg/KgBB, 8000 mg/KgBB, oral sonde was performed once a day then observed after 24 hours for 14 days by looking at the number of deaths and symptoms of toxicity. The results obtained were that the mice experienced symptoms of toxicity, weakness, palpitations and decreased activity, with LD50 in male mice of 4224.511 mg/KgBB, in female mice 3030.354 mg/KgBB categorized as slightly toxic.
INDEKS ERITROSIT PADA PRE EKLAMPSI Nathalya Dwi Kartika Sari; Hartatiek Nila; Ersalina Nidianti; Widya Novita Sari
Klinikal Sains : Jurnal Analis Kesehatan Vol. 13 No. 1 (2025): Juni
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikalsains.v13i1.5390

Abstract

Hypertension in pregnancy ranks as the top cause of death in Indonesia with a value of 33%. Systemic inflammation can be measured using various biochemical and hematological parameters. Preeclampsia (PE) is a complication due to pregnancy that has dangerous risks. Preeclampsia is characterized by high blood pressure and proteinuria. This condition generally appears when the gestational age reaches 20 weeks, is associated with placental hypoperfusion which is the main cause of fetal growth restriction and in severe cases develops into multi-organ dysfunction and even death of the mother and fetus. The aim of this research is to determine the Erythrocyte Index in pregnancies with preeclampsia. The research method used a cross sectional method obtained from medical record data for 1 year (August 2022 to August 2023) from complete blood tests (erythrocyte index) of normal pregnancies and preeclampsia pregnancies carried out at RSI Surabaya A Yani. This research was conducted on pregnant women with preeclampsia and healthy pregnant women at the RSI Surabaya A Yani obstetrics clinic
CYTOTOXICITY ASSAY USING BRINE SHRIMP LETHALITY TEST ON COLLAGEN-CHITOSAN WOND DRESSING STERILIZED BY ULTRAVIOLET LIGHT Ary Andini; Endah Prayekti; Devyana Dyah Wulandari; Ersalina Nidianti
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 2 No 1 (2020): Laboratory Examinations Support in Medical Toxicology
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v2i1.1467

Abstract

Collagen gives a moist state on the wound area to accelerate the wound healing process. Chitosan is a polymer as known as non-toxic, antibacterial, antifungal, biodegradable, and biocompatible materials. Combination of collagen and chitosan expected to be the best biomaterials as a wound dressing for the healing process. The study aimed to determine cytotoxicity assay on collagen-chitosan wound dressing sterilized by ultraviolet (UV) Light using Brine Shrimp Lethality Test (BSLT) method. The test groups were divided into K0, K1, K2, and K3 groups. K0 contained pure chitosan as a control group, K1 contained collagen 25%-chitosan 75%, K2 contained collagen 50%-chitosan 50%, K3 contained collagen 75%-Chitosan 25%. Collagen extracted from skin and scalp of snakehead fish (Channa striata) then mixed with chitosan until formed collagen-chitosan wound dressing. This study used Brine Shrimp Level Test (BSLT) method with solution concentration 10, 50, 100, 250, 500, 750 and 1000 ppm. Based on the results showed that K0, K1, K2, and K3 group had LC50 >1000 that proven collagen-chitosan wound dressing was non-toxic materials. As conclusion of the study explained composite wound dressing based on collagen-chitosan in all groups that sterilized under UV-Light along 15 minutes was not toxic based on Brine Shrimp Lethality Test showed LC50 >1000.
Pengabdian Masyarakat Pemeriksaan Kolesterol dengan Metode POCT dan Pemanfaatan Kulit Buah Naga Merah di Wilayah Mojokerto [Community Service Cholesterol Screening Using the POCT Method and Utilization of Red Dragon Fruit Peel in the Mojokerto Region] Ersalina Nidianti; Annisa Syahrah; Sarafia Pertiwi; Luqiana Fauziyah; Yauwan Tobing Lukiyono
Indonesia Berdaya Vol. 7 No. 1 (2026)
Publisher : UKInstitute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/ib.20261374

Abstract

Non-communicable diseases (NCDs), particularly hypercholesterolemia, are increasing health problems and major risk factors for cardiovascular disease. This community service activity aimed to measure cholesterol levels using the Point of Care Testing (POCT) method and to educate the community on utilizing red dragon fruit peel waste as a natural detection kit for borax and formalin. The program was conducted in Sumbersono Village, Dlanggu District, Mojokerto Regency, over one month (July 2025), targeting local residents and street food vendors around schools and markets. The methods included several stages: planning, cholesterol screening using a POCT device, education on interpreting the results, and the preparation and use of borax and formalin detection kits made from red dragon fruit peel extract. The results showed that approximately 40% of participants had cholesterol levels above normal limits, while 60% were within normal ranges. Testing of seven food samples using both commercial detection kits and natural indicators based on red dragon fruit peel extract yielded negative results for borax and formalin. In conclusion, this community service program successfully integrated health promotion and disease prevention efforts with the innovative use of agricultural waste (red dragon fruit peel). The application of red dragon fruit peel as a natural indicator proved effective, with all tested food samples showing negative results. Abstrak. Penyakit tidak menular (PTM), khususnya hiperkolesterolemia, merupakan masalah kesehatan yang terus meningkat dan menjadi faktor risiko utama penyakit kardiovaskular. Tujuan kegiatan pengabdian masyarakat ini untuk melakukan pemeriksaan kadar kolesterol menggunakan metode Point of Care Testing (POCT) serta mengedukasi pemanfaatan limbah kulit buah naga merah sebagai kit deteksi alami boraks dan formalin. Kegiatan dilaksanakan di Desa Sumbersono, Kecamatan Dlanggu, Kabupaten Mojokerto selama satu bulan (Juli 2025) dengan sasaran masyarakat desa dan pedagang jajanan di sekolah atau di pasar. Metode kegiatan meliputi perencanaan, pemeriksaan kadar kolesterol dengan alat POCT, edukasi hasil pemeriksaan, serta pemanfaatan kit uji boraks dan formalin berbasis ekstrak kulit buah naga merah. Hasil kegiatan menunjukkan bahwa sekitar 40% peserta memiliki kadar kolesterol melebihi batas normal, 60 % peserta kadar kolesterol normal. Pengujian kit deteksi komersial dan indikator alami berbasis ekstrak kulit buah naga merah pada 7 sampel diperoleh hasil negatif. Kesimpulan kegiatan pengabdian masyarakat ini berhasil mengintegrasikan aspek promotif dan preventif kesehatan dengan pemanfaatan limbah pertanian (kulit buah naga). Penggunaan kulit buah naga merah sebagai indikator alami terbukti efektif dengan semua sampel janan yang di uji menunjukkan hasil negatif.
The Effect of Cigarette Smoke Exposure on Blood Nicotine and Glutathione (GSH) Levels in Smokers and Non-Smokers Ersalina Nidianti; Herlianti Anggun Puspita Ningrum; Silva Havadoh Shelagita; Ary Andini; Muhammad Afwan Romdloni
Window of Health : Jurnal Kesehatan Vol 9 No 3 (July, 2026)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/woh.vi.2701

Abstract

Smoking remains a major global public health problem and contributes substantially to morbidity and mortality worldwide. According to the World Health Organization, tobacco use causes more than 8 million deaths annually, including approximately 1.3 million deaths among non-smokers exposed to secondhand smoke. Cigarette smoke contains nicotine and various oxidant compounds that promote free radical formation and oxidative stress, potentially disrupting the antioxidant defense system, including reduced glutathione (GSH), an important intracellular antioxidant. However, evidence simultaneously comparing nicotine exposure and GSH levels between smokers and non-smokers remains limited, particularly in the studied population. This study aimed to compare blood nicotine and GSH levels between smokers and non-smokers. An observational analytical study with a cross-sectional design was conducted among 34 respondents, comprising 17 smokers and 17 non-smokers. EDTA plasma samples were analyzed using UV–Vis spectrophotometry at 258 nm for nicotine and 412 nm for GSH. Differences between groups were analyzed using the Mann–Whitney U test. The mean nicotine level was higher in smokers than in non-smokers (19.18 vs. 5.51 µg/mL), whereas the mean GSH level was lower in smokers than in non-smokers (27.00 vs. 38.82 mg/dL). Significant differences were observed in both nicotine and GSH levels between the two groups (p < 0.001). These findings indicate that smoking is associated with higher nicotine levels and lower GSH levels, suggesting an imbalance in antioxidant defense consistent with increased oxidative stress among smokers.
Hubungan Kejadian Sifilis dengan Human Immunodeficiency Virus (HIV)1.2 Pada Pekerja Seks Komersial Fitri Aisyah Haddad; Rahayu Anggraini; Suprapto Ma’at; Ersalina Nidianti
Cerdika: Jurnal Ilmiah Indonesia Vol. 4 No. 8 (2024): Cerdika: Jurnal Ilmiah Indonesia
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/cerdika.v4i8.833

Abstract

Pekerja Seks Komersial (PSK) biasanya menularkan penyakit menular seksual, sehingga pada kesempatan ini ingin mengetahui penyakit menular seksual (Sifilis, HIV1.2) yang banyak terjadi pada PSK. Penelitian ini menggunakan metode observasional pendekatan desain cross sectional analytic, dengan tujuan untuk mengetahui hubungan kejadian sifilis dengan HIV1.2 pada pekerja seks komersial. Penelitian dilakukan pemeriksaan sifilis metode Rspid dari total responden dan HIV1.2 metode ELISA (Enzym–Linked Immunosorbent Assay). Hasil penelitian didapatkan kejadian sifilis sebanyak 6,7% positif dan 93,7% negatif. Hasil pemeriksaan HIV1.2 didapatkan 6,7% reaktif dan 93,7% non rekatif. Hasil analisis statistik terdapat hubungan yang signifikan kejadian sifilis dengan HIV1.2 dengan nilai p value 0,017 (p<0,05). Kesimpulan, kejadian sifilis dan HIV1.2 terjadi pada individu sama yang artinya teori bakterial vaginosis yang menyatakan kondisi vagina yang bermasalah lebih mudah terinfeksi penyakit menular seksual terutama yang memiliki penyimpangan oral seks
Edukasi Kesehatan dan Skrining Penyakit Rheumatoid Arthritis pada Masyarakat Desa Lampah, Kabupaten Gresik Ersalina Nidianti; Suprapto Maat
Jurnal Pengabdian Meambo Vol. 5 No. 1 (2026): Jurnal Pengabdian Kepada Masyarakat MEAMBO
Publisher : PROMISE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56742/jpm.v5i1.192

Abstract

Prevalensi penyakit sendi berdasarkan diagnosis tenaga kesehatan di Indonesia sebesar 11.9 % dan berdasarkan diagnosis atau gejala sebesar 24.7%. Jika dilihat dari karakteristik umur, prevalensi tertinggi pada umur ≥ 75 tahun (54.8%). Penderita wanita lebih banyak (27.5%) dibandingkan dengan pria (21.8%). Berdasarkan angka kejadian kasus di atas maka perlunya edukasi kesehatan tentang penyakit Rheumatoid Arthritis untuk memberikan penambahan informasi terutama pada penderita Rheumatoid Arthritis yang terjadi pada masyarakat Lampah, Gresik. Kegiatan pengabdian kepada masyarakat ini dilakukan di Balai Desa Lampah Gresik. Metode yang digunakan dalam pengabdian masyarakat ini adalah edukasi kepada masyarakat tentang penyakit Rheumatoid Arthritis (konsep, gejala klinis, pengobatan dan pencegahan). Langkah-langkah yang akan dilaksanakan pada kegiatan pengabdian masyarakat ini yaitu: Survey Lokasi Mitra, Tahapan Persiapan, Tahapan Pelaksanaan (Edukasi penyakit Rheumatoid Arthritis), dan Skrining penyakit Rheumatoid Arthritis, Evaluasi Kegiatan serta Penutupan. Hasil 60% responden berjenis kelamin wanita dan 40% responden berjenis kelamin pria. Pengetahuan tentang penyakit Rheumatoid Arthritis Ya 50% dan Tidak 50%, Sering mengalami Nyeri Sendi, Kaku Sendi, Kelelahan Ya 65%, dan Tidak 35%. Terjadi peningkatan pengetahuan dari 50% menjadi 80%. Kesimpulan bahwa terjadi peningkatan pengetahuan terutama pada penderita Rheumatoid Arthritis yang terjadi pada masyarakat Lampah, Kabupaten Gresik.
Co-Authors Adinda Priyanti Dewi Afianti Diah Anjelia Aidilfi Akbar, Dimas Arendra Aini, Fadlilah Nur Aisah Humairoh Alfina Andasari Algristian, Hafid Alifia Qurotaaini Andini Devi Rizkiyah Andini, Ary Andreas Putro Ragil Santoso, Andreas Putro Ragil Anggara Kidung Pranata Annisa Syahrah Arif Rahman Hakim Ary Andini Atika Maulida Inastiti Aulia, Ilmiah Alvi Nisa Bismi Aisyah Rahma Putri Budury, Syiddatul Cahyani, Yuliana Dwi Kurnia Charissa Balqis Chika Nur Azizah Dea Ayu Rahmawati Desi Susanti Devyana Dyah Wulandari Devyana Dyah Wulandari Dewi Masithah Dina Kamelia Dinda Enka Nita Endah Budi Permana Putri Evi Utul Kasanah Fadilah Nisa Purwanti Fadlilah Nur Aini Fahrizal Amin Nurfaizi Farah Dina Amalia Farah Nuriannisa Farhatu Aini Fauziyah, Luqiana Fitri Aisyah Haddad Gilang Nugraha Halimah Prisilia Hartatiek Nila Herliani Rahmania Sari Herlianti Anggun Puspita Ningrum Herlianti Anggun Puspita Ningrum Herlianti Anggun Puspita Ningrum Hidayat, Muhammad Taufiq Himawan, Toto Hudzaifah Hamidy Ika Maysaroh Lesparwati Ilmiah Alvi Nisa Aulia Intan Oktariza Nuraulya Putri Irmawati Irmawati KARIMAH, AKHLAQUL Khoirul Ngibad Khusnah, Hidayatul Kombih, Muhammad Fifin Kurniasari, Diyan Wahyu Luqiana Fauziyah Maat, Suprapto Mardhotillah, Rachma Rizqina Marotur Rohima Miftakhul Dwi Ersanti Miladiya, Feby Ayu Muhammad Afwan Romdloni Muhammad Afwan Romdloni Muhammad Taufiq Hidayat Mutmainnah Nadzirah Sylvia Nandasari, Anggy Dwipa Nathalya Dwi Kartika Sari Nathalya Dwi Kartika Sari Ngiluhtara Aditiya Putri Nila Dwi Utami Nisrina Salsabila Firdaus Nur A'isyah Oktavianingrum Nurdinata, Sandra Maulida Nuris Lutfika Nurul Hidayatih Nurul Munawaroh Pertiwi, Penti Pertiwi, Sarafia Prayekti, Endah Puspitasari, Fike Putri, Bismi Aisyah Rahma Putri, Ngiluhtara Aditiya Qotrinnada, Nabilah Rahayu Anggraini Rahayu Anggraini Rahmawati Fitri Awalia Raniyah Diva Rosalbah Rezky Dwinda Pratiwi Rizka Amalia Rizka Amalia Rizkiyah, Mubarokator Rohmah, Wardah Rukman, Nia Kurniaty Safitri, Hana Salfa Salsabilah Zain Salfa Salsabilah Zain Salim, Hotimah Masdan Santoso, Rizma Defva Sarafia Pertiwi Sari, Herliani Rahmania Sari, Yuni Nur Malita Saumia Khoirunnisa Syadzila Septyanengrum, Rita Silva Havadoh Shelagita Siska Wulandari, Siska Siti Basiroh Sri Surya Suciati Suciati, Sri Surya Sunaryo, Merry Suprapto Maat Suprapto Maat Suprapto Ma’at Syadzila, Saumia Khoirunnisa Syahrah, Annisa Utami, Nila Dwi Utomo, Edi Priyo Widi Agustin Wulandari Widya Novita Sari Widya Putra, Bima Arya Wieke Sri Wulan Wieke Sri Wulan Wulan, Wieke Sri Yauwan Tobing Lukiyono Yuliani, Kartika Yuni Nur Malita Sari Zain, Salfa Salsabilah