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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Farmasi Sains dan Komunitas JCPS (Journal of Current Pharmaceutical Sciences) Jurnal Mandala Pharmacon Indonesia Jurnal Pengabdian Kepada Masyarakat (Mediteg) Borneo Journal Of Pharmascientech Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Abdi Masyarakat Kita JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Jurnal Farmasi Sains dan Praktis Jurnal Bakti Untuk Negeri JURNAL JAMU KUSUMA Jurnal Pengabdian Kepada Masyarakat: Kesehatan (JPKMK) Sinteza Jurnal Ilmiah Kesehatan Jurnal Pengabdian Masyarakat Panacea JPEPT Journal of Pharmascience
Nur Mahdi
Universitas Lambung Mangkurat
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary

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Effectiveness Test Antidiarrhea of the Combination of Ziziphus Mauritiana Leaves and Curcuma Domestica Rhizome on Male Mice (Mus musculus) Rita Muliyani; Andi Zsazsa Rafiatul Muklis; Nur Mahdi
Journal of Pharmacology Experiment and Pharmaceutical Technology Vol. 1 No. 2 (2025): JPEPT
Publisher : DSM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64015/jpept.v1i2.14

Abstract

Diarrhea is a disease that experiences an increase in fecal mass and the number of bowel movements is more than 4 times per day. Synthetic drugs are often used to treat diarrhea, but they often cause dangerous side effects. Bidara leaves (Ziziphus mauritiana) and turmeric rhizomes (Curcuma domestica) are often used as alternative treatments to treat diarrhea because they contain potential diarrheal drugs. The purpose of this study is to determine the antidiarrheal effect of a combination of bidara leaf ethanol extract (BLEE) and turmeric rhizome ethanol extract (TREE) on male mice that were given PO with oleum ricini. The research method used was experimental with the induction of oleum ricini diarrhea with a combination dose of EEDB and EERK 4mg:2mg/20grBB, 2mg:4mg/20grBB and 4mg:4mg/20grBB. The results of the study with One Way ANOVA with a confidence level of 95% in this study were < 0.05 which means that there was a significant difference and continued LSD tests in all combination groups obtained a meaningful difference with the positive control group (attapulgite). The results of the study concluded that the combination of bidara leaves (Ziziphus mauritiana) and turmeric rhizomes (Curcuma domestica) had a stronger antidiarrheal effect than positive control (attapulgite).
NATURAL WEAPON AGAINST DENGUE: LARVICIDAL EFFICACY OF PAPAYA (Carica Papaya L.) FRUIT PEEL ETHANOL EXTRACT ON AEDES ALBOPICTUS Nidha Luthfiana Fawziah; Nur Mahdi; Andi Zsaza Rafiatul Muklis; Deni Setiawan
Journal of Pharmacology Experiment and Pharmaceutical Technology Vol. 1 No. 2 (2025): JPEPT
Publisher : DSM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64015/jpept.v1i2.17

Abstract

Dengue or, as it is commonly known, dengue fever, has become a public health problem in the world, not only in Indonesia. Until now, dengue disease is still not well controlled. Dengue fever is caused by Aedes argypi and Aedes albopictus mosquitoes. The purpose of this study was to determine the effectiveness of papaya peel extract (Carica papaya L) against Aedes albopictus mosquito larvae. This study is an experimental study of post test only control group design using 600 Aedes albopictus larvae. This study used papaya peel extract with 6 concentration treatment groups of 0.4 mg/ml, 0.8 mg/ml, 0.12 mg/ml, 0.16 mg/ml, positive control group and negative control group. Observations were made 24 hours after treatment and larval mortality was calculated every 1 hour. The results showed that the average larval mortality at a concentration of 0.4 mg/ml was 6.25%, concentration of 0.8 mg/ml was 8.25%, concentration of 0.12 mg/ml was 10.75%, at a concentration of 0.16 mg/ml was 14.5%, for the positive control was 100%, and for the negative control was 0%. The results of probit analysis of LC90 of papaya peel extract amounted to 48.501 and LT50 at the fastest killing concentration of 0.16 mg/ml was 59.017 hours. Based on the results of the study, it can be concluded that papaya peel extract (Carica papaya L.) can kill Aedes albopictus mosquito larvae.
FORMULATION OF LIQUID BATH SOAP WITH PALM LEAF EXTRACT Titin Maulida; Nur Mahdi; Raisha hamiddani Syaiful
Journal of Pharmacology Experiment and Pharmaceutical Technology Vol. 1 No. 2 (2025): JPEPT
Publisher : DSM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64015/jpept.v1i2.18

Abstract

Among the world's top producers of palm oil are Indonesia (47,000), Malaysia (19000), Thailand (3450), and Colombia (1,800). Because it contains bioactive substances like flavonoids, alkaloids, steroids, tannins, and saponification, palm oil waste—more especially, palm fronds—has antioxidant potential and can be used as a raw material to make liquid soap and other cosmetics. Through testing of Indonesian National Standard (SNI) parameters, including the organoleptic test, pH, moisture content, free fatty acids, viscosity, and specific gravity, this study seeks to ascertain if the formula of palm leaf liquid soap has a good stability concentration. In order to test the SNI parameters on the stability of the liquid soap preparation on days 1, 7, 14, 21, and 28, this study used an experimental method with variations of three concentrations of palm leaf extract, namely F1 2%, F2 4%, and F3 6%. The pH and specific gravity tests were conducted using the One Way ANOVA method because the results were normally and homogeneously distributed. Since the data for the viscosity and free fatty acid tests were not normally distributed, the Kruskal Wallis method was applied. The formulations F1 2%, F2 4%, and F3 6% were reported to have no discernible effects or differences on days 1, 7, 21, and 28. Because the liquid bath soap formulation in this investigation produced fewer than 15% free fatty acids, it was determined that it did not meet the SNI requirements for liquid bath soap. The free fatty acid test did not satisfy the SNI requirements, despite the pH, specific gravity, and viscosity tests meeting the SNI parameters for liquid bath soap.  
Analisis Kualitatif dan Kuantitatif Kandungan Senyawa Flavonoid dan Fenolik pada Ekstrak Etanol Daun Mangga Kasturi (Mangifera Casturi Kosterm.) Rahmayani Maghfirah; Mochammad Saiful Bachri; Sri Mulyaningsih; Sapto Yuliani; Nur Mahdi
Journal of Pharmascience Vol. 12 No. 1 (2025): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v12i1.21350

Abstract

Mangga kasturi (Mangifera casturi Kosterm.) merupakan tanaman endemik Kalimantan Selatan yang dikenal dengan buahnya yang memiliki rasa manis dan aroma khas. Tanaman ini tergolong langka dan telah mengalami penurunan populasi di habitat aslinya akibat deforestasi dan kurangnya upaya budidaya. Daun mangga kasturi mengandung senyawa bioaktif seperti flavonoid dan fenolik yang berpotensi sebagai antioksidan alami untuk kajian awal pengembangan obat. Penelitian ini bertujuan untuk mengidentifikasi kandungan flavonoid dan fenolik dalam ekstrak etanol daun mangga kasturi (EEDMK) melalui uji kualitatif dan kuantitatif. Uji kualitatif dilakukan menggunakan uji tabung dan kromatografi lapis tipis (KLT) dengan fase diam silika gel GF254. Fase gerak berupa campuran heksana, etil asetat, dan asam format (6:4:0,2) digunakan untuk flavonoid, sementara campuran CHCl3, metanol, dan aquadest (7:3,5:1) digunakan untuk fenolik. Penetapan kadar flavonoid dilakukan dengan metode spektrofotometri AlCl₃ menggunakan standar kuersetin, sedangkan senyawa fenolik dianalisis menggunakan metode Folin-Ciocalteau dengan standar asam galat. Hasil uji kualitatif menunjukkan adanya senyawa flavonoid dengan nilai Rf 0,43 dan 0,63 serta fenolik dengan Rf 0,1. Uji kuantitatif menunjukkan total kandungan flavonoid dalam ekstrak adalah 8,3625±0,05 mg QE/g, sementara kandungan fenolik total mencapai 219,0196±1,80 mg GAE/g. Hasil ini menunjukkan potensi EEDMK sebagai sumber senyawa bioaktif yang dapat dikembangkan lebih lanjut untuk sediaan farmasi.
Edukasi Perilaku Hidup Bersih dan Sehat serta Pengenalan Konsep Kefarmasian Pada Pelajar SDN Akar Bagantung Lukman Mahdi; Nashrul Wathan; Muhammad Ikhwan Rizki; Satrio Wibowo Rahmatullah; Novia Fahrina Purnama Sari; Hema Novita Rendati; Risa Susanti; Yuniarti Suryatinah; Nur Mahdi; Rina Astiyani Jennah; Dinna Fitria Kumala
Jurnal Pengabdian Kepada Masyarakat (MEDITEG) Vol. 11 No. 1 (2026): Jurnal Pengabdian Kepada Masyarakat (MEDITEG)
Publisher : Pusat Penelitian dan Pengabdian Kepada Masyarakat (P3M) Politeknik Negeri Tanah Laut (Politala)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34128/mediteg.v11i1.397

Abstract

Kesehatan menjadi fondasi penting bagi anak untuk merespons tantangan berbagai penyakit di era ini. Anak perlu distimulasi sedini mungkin untuk membangun karakter peduli kesehatan diri sendiri dan lingkungan. Meskipun saat ini informasi mudah diakses, kemampuan anak dalam menyaring informasi masih kurang sehingga perlu edukasi secara langsung. Kegiatan ini bertujuan untuk meningkatkan pemahaman pelajar SDN Akar Bagantung, Kabupaten Banjar, Kalimantan Selatan terkait perilaku hidup bersih dan sehat (PHBS) serta kefarmasian. Sebanyak 32 pelajar menjadi responden. Teknik edukasi menggunakan pembelajaran aktif yakni ceramah interaktif, video pembelajaran, dan simulasi. Tingkat pengetahuan siswa diukur menggunakan kuesioner sebelum (pretest) dan setelah pembelajaran (posttest). Hasil evaluasi menunjukkan sebanyak 68,75% siswa SDN Akar Bagantung menunjukkan peningkatan pengetahuan terkait PHBS dan kefarmasian. Nilai rata-rata gabungan pelajar setelah diberi edukasi adalah 95,31. Edukasi menggunakan pembelajaran aktif efektif dalam meningkatkan pengetahuan pelajar SDN Akar Bagantung mengenai perilaku hidup bersih dan sehat serta kefarmasian.
Uji Aktivitas Antibakteri Ekstrak Etanol Daun Bintaro (Cerbera odollam) dalam Menghambat Pertumbuhan Streptococcus mutans dan Escherichia coli Nur Mahdi; Susi Susanti; Ani Agustina; Andi Zsazsa Rafiatul Mukhlis
Sinteza Vol. 4 No. 1 (2024): February
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v4i1.21431

Abstract

Tanaman bintaro (Cerbera odollam) salah satu dari banyak tanaman antimikroba yang ditemukan di Indonesia. Tanaman bintaro efektif dalam mengendalikan serangan hama, namun dalam penelitian antibakteri belum banyak diteliti. Penelitian ini bertujuan untuk menguji aktivitas antibakteri ekstrak etanol daun bintaro menghambat pertumbuhan bakteri Streptococcus mutans dan Escherichia coli. Penelitian ini menggunakan metode eksperimental untuk menguji aktivitas antibakteri menggunakan metode difusi cakram. Pengujian dilakukan dengan menggunakan konsentrasi ekstrak daun bintaro terdiri dari 25%, 50%, 75%, dan 100%, kemudian dilanjutkan dengan analisis data menggunakan uji Kruskal Wallis dan uji Chi Square. Hasil penelitian menunjukkan bahwa ekstrak etanol daun bintaro memiliki sifat antibakteri. Pada konsentrasi ekstrak 75% terhadap Streptococcus mutans diperoleh rata-rata zona hambat sebesar 6,125 mm dengan kategori daya hambat sedang dan pada Escherichia coli diperoleh rata-rata zona hambat sebesar 6,5mm. Kemudian pada pada konsentrasi 100% diperoleh pada kedua bakteri tersebut dengan zona hambat 7,5 mm dengan kategori daya hambat sedang. Uji Kruskal Wallis diperoleh nilai signifikansi sebesar 0,003 atau (p < 0,05) menunjukkan perbedaan bermakna. Uji Chi Square menunjukkan nilai signifikansi untuk Streptococcus mutans sebesar 0,433 atau (p < 0,05) dan Escherichia coli sebesar 0,433 atau (p < 0,05). Pada konsentrasi 100% diameter zona hambat 7,5 mm, hasil ekstrak etanol daun bintaro menunjukkan aktivitas antibakteri dengan kategori sedang terhadap bakteri Streptococcus mutans dan Escherichia coli.
Formulasi Sediaan Sabun Cair Ekstrak Daun Ramania (Bouea macrophylla Griffith) sebagai Antiseptik Nur Mahdi; Rezekiah Rezekiah; Agustina Ani
Sinteza Vol. 4 No. 2 (2024): August
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v4i2.25475

Abstract

Ramania leaves (Bouea macrophylla Griffith) are natural ingredients that have activity as an antiseptic. Ramania leaves contain flavonoids, alkaloids, steroids and tannins. This study aims to make antiseptic liquid soap from ramania leaf extract with a concentration of 5%, 10%, 15%. This study used experimental methods in the laboratory. three formulations were made (FI, FII, FIII with a concentration of 5%, 10%, 15%). Evaluation includes organoleptic, homogeneity, pH, specific gravity, foam height. Antiseptic test was carried out using the zigzag method. he antiseptic test was carried out using the replica method. The statistical test for evaluating preparations is One Way Anova, for antiseptic testing using Paired sample t-test. The results of several evaluations have met the requirements, except that the specific gravity does not meet the SNI criteria. The antiseptic test is indicated by the percentage of bacterial reduction. The percentage of bacterial reduction in FI, II, and III respectively was 40.5; 48.5; and 57.5%. It can be seen that increasing the extract concentration can reduce the number of bacterial colonies. The results of the One Way Anova statistical test (a = 0.05) showed that there was no difference in the results of the preparation evaluation, the results of the paired sample test (a = 0.05) showed a significant difference in the antiseptic test. Based on the results of research on the specific gravity test however all formulas do not meet the criteria. In the antiseptic test, all formulas were effective in inhibiting bacterial growth.
Co-Authors Agustina Ani Agustina, Ani Agustina, Ni Kadek Ayu Alpia Damayanti Andi Sultang Andi Sultang AS Andi Zsaza Rafiatul Muklis Andi Zsazsa Rafiatul Mukhlis Andi Zsazsa Rafiatul Mukhlis Andi Zsazsa Rafiatul Muklis Andi Zsazsa RM Anggreni, Nova Ani Agustina Ani Agustina Ani Agustina Ani Agustina Ani Agustina Aulia, Hilma Ayulia Dwi Sandi, Dita Buih, Putri Helena Junjung Chatarina Umbul Wahyuni Deni Setiawan Deni Setiawan Diky Mudhakir Dinna Fitria Kumala Dolih Gozali Dyah Ariani Perwitasari Dyah Aryani Perwitasari Elvita Nurwahdini Farhandika Putra Fatmawati Fitriyati, Fitriyati Hardianti, Sitti Hema Novita Rendati Iis Wahyuningsih Intana Merdeka Sari Izma, Hayatun Juliana Handyka Rosanty Hutasoit Liling Triyasmono Linda Sari Lukman Mahdi Maghfirah, Rahmayani Mahdi, Lukman Malahayati, Siti Maryani, Henny Melindawati, Vina Moch. Saiful Bachri Mochammad Saiful Bachri Muhammad Ikhwan Rizki Muhammad Rasyid Ridha Muhammad Riki Shindi Praristiya Muhammad Riki Shindi Praristiya Muhammad Syarif Hidayatullah Mustika Muthaharah Mustika Muthaharah Nashrul Wathan Nidha Luthfiana Fawziah Noorma Yahni Normaidah, Normaidah Novia Fahrina Purnama Sari Nur Meina Anjeli Nur Meina Anjeli Nuraini Manurung Nurul Mardiati Nurul Wahdah Nyoman Kertia Pertiwi, Hana Retno Rahmatullah, Satrio Wibowo Rahmayani Maghfirah Rahmayani Maghfirah Rahmayani Maghfirah Raisha hamiddani Syaiful Raisha Hamiddani Syaiful Rakhil Zulfansyah Ratnapuri, Prima Happy Rezekiah Rezekiah Rikha Arliandini Rina Astiyani Jennah Rinda, Ririn Purnama Risa Susanti Rita Muliyani Samsul Hadi Samsul Hadi Sapto Yuliani Sari, Okta Mutia Savitri, Riswandayani Shindi, Muhammad Riki Sindi Ahmayanti Siti Nur Farida Sofa, Maida Sri Mulyaningsih Sri Mulyaningsih Sri Sulistyorini, Sri Susi Susanti Syaiful, Raisha Hamiddani Titin Maulida Tuty Alawiyah Ulfah Wilda Maulida Nur Fatimatuzzahra Yuniarti Suryatinah