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All Journal International Journal of Public Health Science (IJPHS) Jurnal Rekayasa Mesin Medical Journal of Indonesia Jurnal Manajemen Pendidikan BERDIKARI : Jurnal Inovasi dan Penerapan Ipteks Biomolecular and Health Science Journal Jurnal Hukum Sasana Jurnal Ilmiah Sarasvati : Bahasa, Sastra, dan Pengajarannya International Journal of Economics, Management, Business, and Social Science Jurnal Disastri: Pendidikan Bahasa dan Sastra Indonesia Journal of Education Research Jurnal Pengabdian Masyarakat : Pemberdayaan, Inovasi dan Perubahan Jubah Raja : Jurnal Bahasa, Sastra, Dan Pengajaran Jurnal Pengabdian Kolaborasi dan Inovasi IPTEKS Jurnal Penyakit Dalam Indonesia Cendikia: Jurnal Pendidikan dan Pengajaran Journal of Education and Pedagogy Greenation International Journal of Law and Social Sciences Jurnal Pengabdian Masyarakat Wadah Publikasi Cendekia Journal Pesona Indonesia Indonesian Journal of Endocrinology Metabolism and Diabetes (InaJEMD)
Agung Pranoto
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Diabetic foot score: a predictive model for leg amputation in patients with diabetic foot disease Vincent, Agustinus; Soelistijo, Soebagijo Adi; Ardiany, Deasy; Pranoto, Agung; Lusida, Michael Austin Pradipta; Pradhevi, Lukita; Saefudin, Rendra Prasetya
Medical Journal of Indonesia Vol. 33 No. 2 (2024): June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.247427

Abstract

BACKGROUND Patients with diabetes mellitus are at a higher risk for peripheral artery disease (PAD) and diabetic foot disease (DFD), which can ultimately result in leg amputation. This study aimed to develop a novel scoring system to predict the risk of leg amputation using widely available modalities, including demographic characteristics and various laboratory data. METHODS This study was conducted at Dr. Soetomo General Hospital and analyzed risk factors for leg amputation in 99 patients with DFD who underwent leg amputation compared with 80 control patients. This study presented a predictive model for leg amputation in patients with DFD, using odds ratio (OR) analysis and logistic regression approach with confidence intervals (CIs) set at 95%. The data analysis was conducted using SPSS software version 25.0. RESULTS PAD (OR 6.52, 95% CI = 2.19–19.37, p = 0.001), high low-density lipoprotein cholesterol (OR 5.97, 95% CI = 2.31–15.43, p<0.001), type of DFD (OR 4.58, 95% CI = 2.14–9.79, p<0.001), poor glycemic control (OR 4.48, 95% CI = 1.78–11.28, p = 0.001), and neutrophil-to-lymphocyte ratio level (OR 1.04, 95% CI = 1.00–1.07, p = 0.025) were the independent predictors for leg amputation. The predictive model, developed using multivariate analysis with an area under the curve of 89%, optimum threshold of 0.5 (score 6), sensitivity of 84.8%, and specificity of 78.8%, indicating a promising approach for predicting leg amputation outcomes. CONCLUSIONS The newly developed diabetic foot score may assist in making decisions regarding therapeutic options for patients with DFD.
Comparison of stingless bee honey and silver sulfadiazine on diabetic wound healing in rat models Fajari, Nanang Miftah; Pranoto, Agung; Perdanakusuma, David Sontani; Prenggono, Muhammad Darwin; Rudiansyah, Mohammad; Nur'amin, Hendra Wana; Syarifa, Yulia; Hasrianti, Nuvita; Saputri, Imelda Nita; Afrianto, Muhammad Irawan; Husna, Annisa Halida
Medical Journal of Indonesia Vol. 34 No. 3 (2025): September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.257974

Abstract

BACKGROUND Diabetic foot ulcers (DFUs) are a major health concern in Indonesia. Adjuvant therapies may improve healing by avoiding secondary infections, promoting angiogenesis, and supporting oxygen circulation. This aimed to evaluate the effect of stingless bee honey (SBH) from Heterotrigona itama on diabetic wound size in rats (Rattus norvegicus), compared to silver sulfadiazine (SSD). METHODS An experimental study was conducted on 13 diabetic wounds in streptozotocin-induced diabetic rats treated with three types of therapies: SSD (n = 5), pure SBH (n = 5), and SBH with 20% water content (n = 3). The study initially involved 21 rats, but eight died during the diabetes modeling and wound observation phases, presumably due to hyperglycemia. Baseline characteristics did not differ significantly across the groups. RESULTS SBH with 20% water content and pure SBH reduced wound size by 95.1% and 92.1%, outperforming SSD (77.4%), with all therapies showing statistically significant improvement (p<0.05). However, the differences between groups were not statistically significant (p = 0.162). CONCLUSIONS Topically applied SBH is a potential natural therapeutic agent for diabetic wounds, in addition to standard treatment such as SSD.
MANAJEMEN KURIKULUM PERGURUAN TINGGI 2025 BERBASIS OUTCOME BASED EDUCATION (OBE) Rawis, Joulanda A. M.; Sumual, Shelty D. M.; Azhar, Yulham; Al Azhar, Baginda Z.; Pranoto, Agung
Jurnal Manajemen Pendidikan Vol. 10 No. 4 (2025): Regular Issue
Publisher : STKIP Pesisir Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34125/jmp.v10i4.1263

Abstract

Objective: This study examines the management of the 2025 Higher Education Curriculum based on Outcome-Based Education (OBE), focusing on curriculum planning, implementation, and evaluation, as well as the extent to which OBE principles are integrated into academic practices. Method: A qualitative exploratory case study approach was employed. Data were collected through in-depth interviews, participatory observations, and curriculum document analysis. Data analysis followed Miles, Huberman, and Saldaña’s Interactive Model, involving data condensation, display, and verification. Results: The findings indicate that the implementation of the OBE-based 2025 Curriculum remains in a transitional stage. While the formulation of learning outcomes (CPL) aligns with OBE standards, consistency varies across programs. Constructive alignment between CPL–CPMK–RPS is not yet optimal, learning practices remain teacher-centered, and curriculum evaluation is not fully data-driven. Institutional challenges include limited lecturer readiness, weak authentic assessment, inadequate digital infrastructure, and insufficient industry collaboration Novelty: This study offers an integrated mapping of OBE-based curriculum management by combining national policy analysis with field evidence, producing a conceptual model for strengthening systemic and sustainable curriculum implementation
Trend Analysis of Clinical Characteristics of COVID-19 with Diabetes Based on Disease Severity Batari Retno Minanti; Soebagijo Adi Soelistijo; Agung Pranoto
‎ InaJEMD - Indonesian Journal of Endocrinology Metabolic and Diabetes Vol. 1 No. 1 (2024): InaJEMD Vol. 1, No. 1
Publisher : PP PERKENI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66266/inajemd.v1i1.1

Abstract

Diabetes Mellitus (DM) increases the risk of COVID-19's severity and mortality than those without DM. The aim of this study was to determine the characteristics and trends by disease severity of DM patients with COVID-19. Across-sectional study examining retrospective medical records was conducted in patients with diabetes mellitus who were confirmed to have COVID-19 by reverse transcription-quantitative polymerase chain reaction (RT-qPCR). All adult patients (age > 18 years) with DM and COVID-19 registered and treated at the Surabaya Hajj General Hospital from May 2021 to the end of December 2021 were included in this study. Trends in each subject's characteristics are displayed in a graph with a trendline based on the severity of COVID-19. The highest proportionof disease severity of DM patients with COVID-19 is mild and moderate cases (72.2%), with 27.8% severe and critical cases. The average aged of the subjects was 56.38 ± 9.60 years. The age group with the highest proportion was 50-59 (42.6%). There are slightly more female than male patients (50.4% vs. 49.6%). The tendency is that the disease's severity increases with BMI, increasing HbA1C level, low sodium level, high chloride level, and high CRP and D-dimer levels. The pattern of clinical and laboratory features of DM patients based on the severity of COVID-19 infection shows the tendency for the disease severity worsens with increasing BMI, HbA1C level, low sodium level, high chloride level, and high CRP and D- dimer levels.
Pregnancy Following Recent Radioactive Iodine Ablation in Thyroid Cancer Patient A Case Report Robert Dwitama Adiwinoto; Soebagijo Adi Soelistijo; Hermina Novida; Agung Pranoto
‎ InaJEMD - Indonesian Journal of Endocrinology Metabolic and Diabetes Vol. 1 No. 1 (2024): InaJEMD Vol. 1, No. 1
Publisher : PP PERKENI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66266/inajemd.v1i1.7

Abstract

Well-differentiated thyroid carcinoma (DTC) is common among females of reproductive age. Pregnancy is associated with hormonal (TSH and HCG) and metabolic changes that might affect the thyroid gland. Informationregarding the outcome of babies born to mothers who have recently undergone radioactive Iodine-131 ablation (RAI) is scarce. A 24-year-old pregnant woman with a history of thyroid cancer was consulted by the obstetrics and gynecology for further evaluation. She complained of a lump under the left jaw, and a thyroid nodule was found from further examination. Postoperative pathology of the right thyroid tissue revealed follicular and solid variant papillary thyroid carcinoma. Postoperative Thyroglobulin (Tg) level before ablation was 16.14 ng/mL. Ablation with Iodine-131 of 100 mCi was performed. Whole-body scintigraphy (WBS) indicated remaining functional thyroid tissue in the right thyroid field and thyroid tissue metastases in the left supraclavicular area. The patient waspregnant 3 months after the radioablation. Fetomaternal examination results 6 months pregnancy revealed fetal biometry according to gestational age (31 – 32 weeks) with an estimated fetal weight of 1787 grams and fetal doppler was normal. The patient is treated with levothyroxine 125 μ g once daily, folic acid 400 μ g twice daily, calcium lactate twice daily, and aspirin 80 mg once daily. The TSH level was 0.01 (0.55 – 4.78) μ IU/mL and the fT4 was 1.14 (0.7 – 1.48) ng/dL. The latest thyroid ultrasound indicated no discrete mass in the thyroid fossa and non-specific lymphadenopathies. The baby was born normally, weighed 2680 grams, with normal thyroid function tests (neonatal TSH 1.02 μ IU/mL, fT4 2.6 ng/dL).
Challenges in the Diagnosis and Management of Adrenal Insufficiency Febri Kurniawati; Sony Wibisono Mudjanarko; Soebagijo Adi Soelistijo; Agung Pranoto
‎ InaJEMD - Indonesian Journal of Endocrinology Metabolic and Diabetes Vol. 1 No. 1 (2024): InaJEMD Vol. 1, No. 1
Publisher : PP PERKENI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66266/inajemd.v1i1.9

Abstract

Adrenal insufficiency (AI) is a rare endocrine condition. Primary adrenocortical insufficiency, or Addison diseases reduces the production of crucial hormones, including glucocorticoids, mineralocorticoids, and adrenal androgens. Due to the lack of proper cortisol response in adrenal crisis, it can be life-threatening during times of stress, emphasizing the need for a timely diagnosis. Despite this, diagnosing and managing AI still presents significant challenges. We report the case of a middle-aged woman who presented with complaints of weight loss, abdominalpain, lethargy, hyperpigmentation of the skin and mucosa, and a history of repeated hospitalizations for nausea, vomiting, dehydration, and hypovolemia. During the patient's previous hospitalization, Addison's crisis was suspected, and methylprednisolone therapy was administered, rendering the cortisol and ACTH assays inaccurate. The patient's condition subsequently improved. The subsequent monitoring revealed low cortisol levels, but an ACTH stimulation test was unavailable. The presence of pulmonary tuberculosis was indicated by a positive chest X-ray and IFN-Gamma Release Assay (IGRA) test. With a history of repeated hospitalizations, suspected Addison's crisis, hypoglycemia, mineralocorticoid involvement (hypotension, hyponatremia), and the presence of hyperpigmentation, a clinical diagnosis of primary adrenal insufficiency was made with limited conditions and testing tools. The patient was given anti-tuberculosis treatment and the lowest dose of hydrocortisone required to control the disease without causing side effects.
Co-Authors Afrianto, Muhammad Irawan Agung, Dimas Pandan Agustin, Widia Al Azhar, Baginda Z. Annisa Halida Husna, Annisa Halida Ardiany, Deasy Ari Sutjahjo, Ari Ariana, Audy Meutia Arjo, Waldetrudis Kamona Askandar Tjokroprawiro Awaloedin, Dipa Teruna Azhar, Yulham Batari Retno Minanti Cik, Achmad Daniel Happy Putra Davin, Moch Arya Dian Ariani Djoko W. Soeatmadji Dwitama Adiwinoto, Robert Febri Kurniawati Febrianti, Fosa Natalia Fitriyanti, Ririn Aunia hadi, sueb Hasrianti, Nuvita Hermina Novida, Hermina Hidayat, Nabiilah Salmaa Dhiyaa I Ketut Suastika Jayawarsa, A.A. Ketut Jongky H Prajitno, Jongky H Joulanda A. M. Rawis Kartika Irene Widjanarko Widjanarko Karyatun, Subur Kaswadi Kaswadi, Kaswadi Latifah, Lailatul Lisrandy, Satria Bayu Lusida, Michael Austin Pradipta Mohammad Rudiansyah Muhaimin, Rahayu Siti Nanang Miftah Fajari Niken Larasati Novita Kurnia Sari Nur'amin, Hendra Wana Nuraini , Sulfani Nurani Nurmalita, Anindia Perdanakusuma, David Sontani Prabandari , Inna Pradana Soewondo Pradhevi, Lukita Pradini, Gagih Prenggono, Muhamad Darwin Primasatya, Chandra Adi Irawan Putra, Suadi Sapta Rahmah, Syafira Atika Rakhmanda, Terisa Dwi Riyanto, M. Riziq, Muhammad Miftah Robert Dwitama Adiwinoto Roely Ardiansyah, Roely Ronald Pratama Adiwinoto Rubiyanti , Rubiyanti Saefudin, Rendra Prasetya Safitri, Adelia Novisa Safitri, Adellia Novisa Saputra, Rivaldo Ihzan Saputri, Imelda Nita Sembiring, Rinawati Setyaningsih Setyaningsih, Setyaningsih Shelty D. M. Sumual Sidartawan Soegondo Siti Aminah Soelistijo, Soebagijo Adi Sony Wibisono Sueb Suharsih, Tulus Syarifa, Yulia Thamrin, Husin Titong Sugihartono ulfa, siti maria maria Ulvia, Rengganis Utami, Widya Utami, Yulianti Dwi Vincent, Agustinus Wulandari, Desvia