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All Journal International Journal of Public Health Science (IJPHS) Pharmaciana: Jurnal Kefarmasian Jurnal Farmasi Sains dan Komunitas JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Journal Of Holistic Nursing Science Jurnal Keperawatan Muhammadiyah Global Health Management Journal JPSCR : Journal of Pharmaceutical Science and Clinical Research CERATA Jurnal Ilmu Farmasi Jurnal 'Aisyiyah Medika Jurnal Aisyah : Jurnal Ilmu Kesehatan Community Empowerment Cendekia Medika : Jurnal Stikes Al-Ma`arif Baturaja Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Sains dan Praktis Urecol Journal. Part E: Engineering Urecol Journal. Part D: Applied Sciences Prosiding University Research Colloquium Borobudur Pharmacy Review Gaster CERATA Medical Sains : Jurnal Ilmiah Kefarmasian Journal of Tropical Pharmacy and Chemistry
Prasojo Pribadi
Universitas Muhammadiyah Magelang, Indonesia
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary

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Hepatotoxicity Risk Profile of Indonesian Due to Polymorphism of NAT2 and CYP2E1 in Isoniazid Metabolism Setiyo Budi Santoso; Puji Umi Chabibah; Prasojo Pribadi
Urecol Journal. Part D: Applied Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53017/ujas.11

Abstract

This article presents data on drug-induced liver injury events' risk profile due to NAT2 and CYP2E1 polymorphisms in isoniazid metabolism in Indonesian populations among various populations of several countries. The research took place through a review of the literature obtained from google scholar. The library search uses three variants of the keyword: (1) "pharmacogenomic and tuberculosis and INH and NAT2 and CYP2E1 and polymorphism", (2) "isoniazid and hepatotoxicity and polymorphism and N-acetyltransferase," (3) "isoniazid and hepatotoxicity and polymorphism and CYP2E1". Analysis of hepatotoxic risk based on the odds ratio (confidence interval) using Stata MP 14th edition software. The study of drug-induced liver injury events' risk based on various NAT2 acetylation rates involved 2,140 populations from 8 countries, while the risk analysis based on CYP2E1 allele variety involved 1,530 populations from 5 countries. The literature review shows that the Indonesian population's isoniazid-induced liver injury events' risk with slow acetylator NAT2 enzymes and people with CYP2E1*c1/c2 is three times higher than other populations in various countries. Further, people who have the combination slow acetylator NAT2 and CYP2E1*c1/c2 have more drug-induced liver injury events' risk.
Kesiapan Apoteker dalam Memberikan Layanan Medication Therapy Management Heni Lutfiyati; Prasojo Pribadi; Setiyo Budi Santoso
CERATA Jurnal Ilmu Farmasi Vol 10 No 1 (2019): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v10i1.74

Abstract

Optimizing the implementation of the referral program is one of BPJS 'top programs. BPJS Health implements a referral program based on Medication Therapy Management. Medication therapy management interventions can reduce the frequency of drug-related problems, including non-compliance, and reduce health care costs. The purpose of this study was to evaluate the readiness of pharmacists in providing medication therapy management services This research uses a descriptive method by using a questionnaire as an instrument for data retrieval. The sampling technique is convenience sampling. The population is pharmacists who practice pharmaceutical services and are willing to fill out questionnaires. The result most pharmacists feel they have enough clinical knowledge and experience to provide MTM services. There are still many pharmacist workplaces (Puskesmas, Pharmacies and hospitals) that have not yet prepared to provide MTM services. Pharmacists think they have a desire to provide MTM services and have sufficient access to information in designing appropriate MTM services and pharmacists should be involved in providing MTM services. The obstacles faced by pharmacists in providing MTM services are insufficient time, insufficient human resources, limited space, limited information regarding MTM services, and the costs needed to implement MTM. Pharmacists are willing to provide Medication Therapy Management services but many obstacles remain. Training is needed so that pharmacists become more confident in providing clinical services
THE EFFECTIVENESS OF JERUJU PLANT EXTRACT (ACANTHUS ILICIFOLIUS) AS ANTICANCER: LITERATURE REVIEW Aziza Vira Arunita; Heni Setyowati Esti Rahayu; Prasojo Pribadi
Gaster Vol 21 No 1 (2023): FEBRUARI
Publisher : P3M Universitas 'Aisyiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30787/gaster.v21i1.865

Abstract

One of the plants that live in Indonesia and has many benefits is Acanthus ilicifolius or jeruju. The jeruju plant is included in the Acanthus family plant which is used for traditional medicine. One of the benefits of the jeruju plant is as an anticancer. The literature search process related to Acanthus ilicifolius and anticancer was carried out using an electronic data base. The purpose of this literature review is to determine the effectiveness of jeruju plant extracts as anticancer and research methods used in previous studies. Jeruju plant extract can be used as an anticancer and has the potential to inhibit the proliferation of HeLa cervical cancer cells. In jeruju leaf extract contained flavonoids, saponins and terpenoids as anticancer compounds with cytotoxic activity values in isolates showed an IC50 value of 88.89 ug/mL. The test method is MMT with maceration extraction method and methanol solution.
MEDICINES PLANNING AND PROCUREMENT MANAGEMENT AN ACADEMIC HOSPITAL IN YOGYAKARTA, INDONESIA: A QUALITATIVE STUDY Elmiawati Latifah; Elfride Irawati Sianturi; Prasojo Pribadi; Indriyati Hadi Sulistyaningrum; Rakhmundia Aryo
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 2 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i2.845

Abstract

Inventory management remains a critical issue for hospital pharmacies. Thus, there is a need for pharmaceuticals to meet economic resources. Moreover, the decision to make drug requests available should be considered, and the complexity of the problem lies in the random nature of and the various constraints that must be considered in any decision. This study aimed to analyze drug management during the planning and procurement stages of medicine in a teaching hospital in Yogyakarta. The qualitative method was used to his type of research is descriptive-analytical with a case study design of one of the public, academic hospitals in the Yogyakarta area. Data collection was conducted through interviews using a content analysis approach. The analysis technique was carried out by reducing data, analyzing data, identifying themes, and extracting data interpretation with the help of NVIVO 12 software. Overall, interviews were conducted with six participants to obtain information on drug management during the planning and procurement stages in the hospital, following the standards of home pharmacy services. The stages also included budget allocation by volume of services, increasing the competence of human resources, which supports the improvement of drug management performance, implementation of e-prescribing to facilitate monitoring evaluation, and availability of complete standard operating procedures. However, the accuracy of drug planning still needs to be improved so that an integrated management information system can support optimal drug management in a teaching hospital pharmacy installation. Keywords: Drug management, drug planning, drug procurement, public academic hospital
Design of Information Systems in Web-Based Medicine Ordering and Procurement Vaira, Tischa; Rohmah, Alfiyatu; Zaeniyah, Siti; Pribadi, Prasojo; Santoso, Setiyo Budi
Urecol Journal. Part E: Engineering Vol. 3 No. 1 (2023): January-June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53017/uje.255

Abstract

The drug distribution process determines the sustainability of drug stocks in pharmaceutical services. It is hoped that the design of an information system for drug procurement and ordering can make the distribution process more effective and efficient. While information systems for drug procurement and ordering exist, they are typically designed for individual distributors. This research aims to design an information system by displaying flowcharts that map the drug procurement and ordering process, and by developing user interfaces that facilitate interaction with the system. The research was carried out through a Literature Review. Reference searches were conducted using the Google Scholar search engine. The keywords used in the keyword search were "pharmaceutical wholesalers AND information system design AND drug procurement" and the references selected were within the last 10 years. The information system design was implemented by creating flowchart diagrams using draw.io software and developing user interface designs using Microsoft Office PowerPoint 2019. The drug procurement and ordering information system can be accessed by PBFs as distributors and pharmacists as consumers. The information system designed is included in the e-Health Commerce Application type, which aims to facilitate the payment process and reduce costs incurred by the health environment. The designed information system can create a more efficient drug distribution process.
The behavioral intention telepharmacy questionnaire based on theory of personal health differences and planned behavior Sulistyaningrum, Indriyati Hadi; Widodo, Teguh; Suyanto, Achmad Manshur Ali; Pribadi, Prasojo
International Journal of Public Health Science (IJPHS) Vol 13, No 2: June 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i2.23357

Abstract

Modern pharmaceutical services are offered via telepharmacy, an internet platform. Identification of items and factors that influence people's behavioral intentions towards telepharmacy services is needed to develop this service. The study aims to develop a questionnaire based on a research model that combines two well-known theories: the theory of personal health differences (TPHD) and the theory of planned behavior (TPB) technique. The purposive sampling strategy was combined with a cross-sectional observational method. 116 participants who were at least 18 years old were given the questionnaire. Convenience sampling from various population subgroups was used to select them. Data analysis was then conducted using the exploratory factor analysis (EFA). Factors were extracted using varimax rotation and principal component analysis. The results showed that the questionnaire consists of 16 items divided into 5 constructs (attitude and self-efficacy, behavioral intention, subjective norm, personal health status, and personal health value), this study proves that the behavioral intention telepharmacy questionnaire based on personal health differences and planned behavior theory is a reliable and valid measure. It can also draw attention to the many aspects of adoption behavior, helping service providers toward the successful digitalization of pharmaceutical services by fostering telepharmacy literacy. The application of telepharmacy is both a hope and a challenge for pharmacists and society, especially in terms of the intention to provide safe and quality pharmaceutical care.
Antidiabetic Activities of Broccoli Extracts (Brassica oleracea L.var italica) on Mice Induced Streptozotocin-Nicotinamide Heni Lutfiyati; Fitriana Yuliastuti; Imron Wahyu Hidayat; Prasojo Pribadi; Sodiq Kamal
Journal of Tropical Pharmacy and Chemistry Vol. 4 No. 4 (2018): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v4i3.203

Abstract

Several plant species have been used for the treatment of diabetes. Research on plants that can be used to treat diabetes such as Cinnamomum cassia and Cinnamomum zeylanicum, Piper sarmentosum Roxb, Nelumbo nucifera, Ceiba petandra Memecylon malabaricum. Broccoli (Brassica oleracea L var italics) is a flower of vegetables like cabbage plants. Broccoli juice is made capable of direct and indirect effects on the reduction of blood LDL; the indirect effect is by repairing pancreatic beta cells and increasing insulin sensitivity. The purpose of this study was to determine whether broccoli has activity as antidiabetic. The subjects consisted of 15 mice induced with nicotinamide 70 mg/kg BW and Stz 150 mg/kg BW. Diabetic mice were divided into the positive control group (glibenclamide), negative control group (CMC Na) and three treatment groups. The test material is broccoli extract dose 75 mg / kg BW, 150 mg /kg BW and 300 mg/kg BW given peroral for 14 days. Anova test results showed that there was a significant difference in the average percentage of decreased blood glucose levels in all treatments. The result of Post Hock Tukey HSD test with a 95% confidence level showed a significant difference in the negative control group compared with positive control group and extract 300mg / kg BW. This shows that positive control group and extracts 300mg / kg body weight have an activity to decrease blood glucose level.
Kandungan Fitokimia dan Aktivitas Farmakologi Tanaman Mangrove Jeruju (Acanthus ilicifolius): Narrative Review Audrea Arnetta Deandra; Diva Atfal Prayoga; Elmiawati Latifah; Arief Kusuma Wardani; Puspita Septie Dianita; Prasojo Pribadi; Rahayu, Heny Setyowati Esti; Kartika Wijayanti
CERATA Jurnal Ilmu Farmasi Vol 15 No 2 (2024): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v15i2.1270

Abstract

Mangroves are woody plants that thrive in wet, muddy, and brackish water habitats found in tropical and subtropical regions. Mangroves are commonly found in Indonesia. One type of mangrove plant is Acanthus ilicifolius L., which can be utilized for medicinal purposes due to its phytochemical content. The aim of this narrative review is to provide information and an overview of the potential phytochemical and pharmacological activities present in each part of the mangrove plant jeruju, along with the solvents and testing methods used. The method employed in this narrative review involves searching for relevant articles on the internet through databases such as Google Scholar, Springer Open, Science Direct, and PubMed. According to several studies, methanol solvent yields the best results as it extracts the most phytochemical content from the mangrove jeruju. The leaves and stems of the mangrove jeruju are the most researched parts because they are the most dominant and easiest to treat. Research findings indicate that the leaves and stems of the jeruju plant contain the highest amounts of alkaloids, tannins, terpenoids, phenols, and flavonoids, with antimicrobial activity being the most commonly found pharmacological potential.
Health Related Quality of Life (HRQoL) in Type 2 Diabetes Mellitus Patients Based on Antidiabetic Prescription Patterns Sari, Seftika; Pratiwi, Erniza; Farahdilla, Dinda; Ghozali, MT; Sulistyaningrum, Indriyati Hadi; Pribadi, Prasojo
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 1 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.008444

Abstract

Diabetes mellitus is characterized as a multifaceted metabolic disorder marked by elevated blood sugar levels or hyperglycemia. Among its types, type 2 diabetes mellitus is the most common globally, significantly affecting a large portion of the population. In Indonesia, there has been a notable increase in the prevalence of type 2 diabetes, indicating a rising trend. This condition necessitates continuous care and management since it is incurable, requiring patients to undergo lifelong treatment. The various therapeutic approaches available for managing type 2 diabetes have a significant impact on the quality of life of patients, highlighting the necessity for quality-of-life assessments. The primary objective of this study was to assess the quality of life among individuals diagnosed with type 2 diabetes mellitus. It also aimed to investigate the effects of different patterns of antidiabetic drug prescriptions on the Health-Related Quality of Life (HRQoL), employing the Diabetes Quality of Life Clinical Trial Questionnaire (DQLCTQ) for evaluation. This study was conducted as a quantitative, observational research using a cross-sectional approach and a descriptive analytical method. A total of 99 participants were included through purposive sampling, a non-probability sampling technique. The findings showed that the average quality of life score was 70.56, with 48 participants (48.5%) reported to have a good quality of life and 51 (51.5%) considered to have a poor quality of life. Importantly, significant results (p0.05) were found regarding the positive effects of combining oral antidiabetic drugs with insulin on enhancing the quality of life in individuals with type 2 diabetes, underscoring the influence of medication regimens on patient health outcomes.
Analisis tingkat kepuasan konsumen terhadap pelayanan kefarmasian di apotek pendidikan X Kabupaten Magelang Bunga, Cut Dewi; Rianawati, Luluc; Yulaikah, Ariska; Latifah, Elmiawati; Yuliastuti, Fitriana; Pribadi, Prasojo
Borobudur Pharmacy Review Vol 5 No 1 (2025): January- June
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v5i1.13180

Abstract

The growing recognition of health's significance among the public drives healthcare facilities such as pharmacies, to enhance the quality of their services. Pharmacies are increasingly emphasizing pharmaceutical services that have transitioned from a drug-centric approach to one that prioritizes the patient. This shift aligns with the principle of pharmaceutical care, which focuses on enhancing the quality of life for patients, while also responding to the growing competition in the market and the demands for consumer satisfaction. Educational pharmacies serve a crucial function as a venue for learning and practical experience for future professionals in the pharmaceutical field. This investigation seeks to assess the degree of consumer satisfaction regarding pharmaceutical services at Pharmacy Education X located in Magelang Regency. The study employs a quantitative descriptive methodology utilizing Likert scale measurements. This study employs a cross-sectional design utilizing a questionnaire that encompasses five dimensions: empathy, physical aspects, responsiveness, assurance, and reliability, aimed at assessing consumer satisfaction. The sample included 100 respondents selected through the convenience sampling method. The findings for the empathy dimension were 96.8%, the physical dimension also recorded 96.8%, the responsiveness dimension showed 96.3%, the assurance dimension reached 98.3%, and the reliability dimension was at 97.5%. In summary, there is a high level of satisfaction among consumers regarding the pharmaceutical services provided at Educational Pharmacy X in Magelang Regency, reflected in an impressive average consumer satisfaction percentage of 97.14%.
Co-Authors . Lolita A.A. Ketut Agung Cahyawan W Abiyana, Setya Rini Achmad Manshur Ali Suyanto Agus Wisudawan A.W Ahmad Faiz Makarim Anggitha, Shelvia Lharas Aninda Tri Yuliasari Arief Kusuma Wardani Arifin Santoso Asmaul Husna Audrea Arnetta Deandra Azis Ikhsanudin Aziza Vira Arunita Basu Swastha Dharmmesta Bunga, Cut Dewi Cut Dewi Bunga Dhuta Sukmarani Diah Kartika Putri Dimas Ariandi Candra Putra Diva Atfal Prayoga Dona Muin Dwi Anggraeni Candrawati, Ira Dwiky Miftahuda Elfride Irawati, Elfride Farahdilla, Dinda Farida, Farida Farrukh, Muhammad Junaid Fathul Muin Fitriana Yuliastuti friski, oktavia Ghozali, MT Hapsari, Widarika Santi Heni Lutfiyati Heni Lutfiyati Heni Lutfiyati, Heni Heni Setyowati Esti Rahayu Heni Setyowati Esti Rahayu Hidayat, Imron Hidayat, Imron Wahyu I Gusti Bagus Wiksuana Imron Hidayat Imron Wahyu Hidayat Imron Wahyu Hidayat Imron Wahyu Hidayat Indah Fortuna Rahmawati Indriatri Septidaryanti Indriyati Hadi Sulistyaningrum Indriyati Hadi Sulistyaningrum Ira Dwi Anggraeni Candrawati Ira Dwi Anggraeni Candrawati, Ira Dwi Anggraeni Jason Merari Peranginangin Kartika Wijayanti Majid, Nur Reviana Makarim, Ahmad Faiz Merari P, Jason Mia Annida Amalia Miftahuda, Dwiky Nesya Jeihan Daniswara Ngesti Rahayu Nia Afifatul Ulya Nora Nur Aini Nur Reviana Majid Nurul Umi Salamah Nurul Umi Salamah oktavia friski Pendri, Widi Wilpa Pratiwi, Erniza Puji Umi Chabibah Puput Widha Puput Widha, Puput Puspita Septi D Puspita Septie Dianita Puspita Septie Dianita Puspita Septie Dianita, Puspita Septie Putra, Dimas Ariandi Candra Putri Diana Savita Putri, Diah Kartika Rahayu, Heny Setyowati Esti Rahayu, Ngesti Rahmawati, Indah Fortuna Rakhmundia Aryo Ratna Wijayatri Rayi Citra Ayu Pangestuti Rianawati, Luluc Rifa Rizqi Azizah Rohmah, Alfiyatu Rohmayanti Rohmayanti Rohmayanti Rohmayanti Safi'a, Winda Alawiyah Salamah, Nurul Umi Santoso, Setiyo Budi Savita, Putri Diana Setiyo Budi Santoso Shelvia Lharas Anggitha Silvia Mareti Siti Rahayu Nurjanah Sodiq Kamal Teguh Utama Teguh Widodo Tiara Mega Kusuma Vaira, Tischa Widarika Santi Hapsari Widya Krisna Murti Winda Alawiyah Safi'a Yulaikah, Ariska Yuliani, Rizka Prita Zaeniyah, Siti