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All Journal Smart Medical Journal Jurnal Respirologi Indonesia Majalah Kedokteran Andalas Jurnal Respirasi (JR) Health and Medical Journal Indian Journal of Forensic Medicine & Toxicology Respiratory Science Cermin Dunia Kedokteran
Putra, Andika Chandra
Departemen Pulmonologi Dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Indonesia-RSUP Persahabatan, Jakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Journal : Respiratory Science

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Evaluation of Mortality Risk Factors of COVID-19 in Jakarta Tertiary Hospital During Peak of Second Wave and Predictive Utility of Community RT-PCR Low CT Values Putra, Andika Chandra; Burhan, Erlina; Aufa, Akhdan; Bur, Rika; Pangestu, Hendri; Bahri, Syukrini; Souvriyanti, Elsye; Muchtiar, Mulyadi; Erlina, Andi; Aditama, Tjandra Yoga; Yuliwulandari, Rika; Kusuma, Indra; Suciati, Yulia; Rifqatussaadah, Rifqatussaadah; Jalal, Fasli; Gusnanto, Arief; Utomo, Ahmad Rusdan H
Respiratory Science Vol. 4 No. 2 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i2.133

Abstract

Background: The Delta variant of SARS-CoV-2 led to a surge in COVID-19 cases in Indonesia. This study aimed to assess the demographic profile and mortality rates of hospitalized COVID-19 patients in YARSI referral hospital, Jakarta, comparing pre-Delta and Delta wave periods. The study also investigated whether low CT values in RT-PCR tests indicated heightened viral transmission before the Delta wave surge. Method: A retrospective analysis was conducted on 1,457 COVID-19 patients hospitalized at YARSI (January-August 2021) and 25,279 RT-PCR test results from walk-in patients (April-August 17, 2021). Differences were evaluated using Chi-square or Fisher’s Exact Tests while binary logistic regression was used to assess mortality risk factors. Results: There were increased proportions of pregnant women, patients aged 20-29 and those with coronary artery disease during the Delta wave. This period also showed a significant increase in mortality rates, with the highest seen in patients >60 years old or those with multiple comorbidities. Notably, most of the deceased patients (131 of 139) were unvaccinated. Analysis of RT-PCR data showed rising percentages of positive results with low CT values (below 21 or 15) from April to June. Conclusion: The Delta wave saw a higher risk of hospitalization among young individuals and pregnant women, despite their low mortality risk. The unvaccinated and those with multiple comorbidities faced higher mortality risks. Increases in RT-PCR positivity with low CT values preceded the July COVID-19 case surge.
Co-Authors Agus Dwi Susanto Agustiyanti, Dian Fitria Ahmad Hudoyo Amien, Bagus Radityo Ana Rima Setijadi Andarini, Sita Anky Zannati Anwar Jusuf Arfiansyah, Mochammad Aris Arif Santoso Aufa, Akhdan Aulya Fairuz Azika, Wira Norman Bahri, Syukrini Bettia Bermawi Budhi Antariksa Budi Haryanto C. Krismini Dwi Irianti Dewi Yennita Sari Elisna Syahruddin Elsye Souvriyanti, Elsye Erdayani, Eva Erlina Burhan Erlina, Andi Ermayanti, Sabrina Fariz, Nurwidya Fasli Jalal Fransiska Fransiska Ginindha Izzati Sabila Gusnanto, Arief Haryati Haryati Hendra Koncoro Hera Afidjati Herjuno Ari Nugroho, Herjuno Ari Hidayat, Moulid Ibrahim Nur Insan Putra Darmawan Idris Idris Ifan Aulia Candra Indra Kusuma Indriawati, Indriawati Infianto, Andreas Isbaniah, Fathiyah Jamsari Jamsari Jasminarti, Ida Ayu JB Endrotomo Sumargono Kurniawan, Ferry Dwi Laksmi Wulandari Laurentius Aswin Pramono Maria Edith Sulistio Mohamad Fahmi Alatas Mohammad Fahmi Alatas Muammar Emir Ananta Muchtiar, Mulyadi Muhamad Rizqy Fadhillah Muhammad Alkaff Noni Novisari Soeroso Pangestu, Hendri Popi Hadi Wisnuwardhani, Popi Hadi Rachmat Hamonangan Ramzi Ramzi RATIH ASMANA NINGRUM Ratna Moniqa Retno Ariza Soeprihatini Soemarwoto Ridwanuloh, Asep Muhammad Rifqatussaadah, Rifqatussaadah Rika Bur Rika Yuliwulandari, Rika Rita Rogayah Robert Sinto Samoedro, Erlang Saniyyah, Zahrah Santoso, Andintia Aisyah Setiawan, Ruby Setyawan, Ryan Haryo Setyawan, Ungky Agus Soehardiman, Dicky Sri Melati Munir Steven Jonathan Sushadi, Pangda Sopha Syazili Mustofa Taufik, Feni Fitriani Tjandra Yoga Aditama Utomo, Ahmad Rusdan H Utomo, Ahmad Rusdan Handoyo wahyuni wahyuni Wawan Abdullah Setiawan Wira Winardi Wiwien Heru Wiyono Wulandari, Ari Sulistyo Yanwirasti Yulia Suciati Zaini, Jamal