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All Journal JCRS (Journal of Community Research and Service) Jurnal Mandala Pharmacon Indonesia Hydrogen: Jurnal Kependidikan Kimia Abdimas Indonesian Journal Jurnal Pengabdian Masyarakat Panacea Journal of Pharmaceuticals and Natural Sciences al Kimiya : Jurnal Ilmu Kimia dan Terapan Jurnal Sains dan Kesehatan Jurnal Riseta Naturafarm Jurnal Pendidikan MIPA
Laode Rijai
Fakultas Farmasi Universitas Mulawarman
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Journal : Journal of Pharmaceuticals and Natural Sciences

 1 
Anti-inflammatory Effect of n-Hexane Fraction of Kentut leaves (Paederia scandens L.) on Male White Rats (Rattus novergicus) Yazid, Muhammad Ilfan; Rijai, Laode; Ahmad, Islamudin
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 1 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/mpbb3e50

Abstract

The anti-inflammatory effect of fart plant leaf extract (Paederia scandens L.) on white rats (Rattus norvegicus) has been carried out. This research shows that the effective dose of the n-hexane fraction of P. scandens leaf extract provides the best anti-inflammatory effect on white rats' feet soles. The study used an artificial edema formation method and periodically measured the volume of white mice's legs using a plethysmometer. The doses used for the extract are 100mg/200g BW, 150mg/200g BW, and 200mg/200g BW. The research data was observed visually. The effective dose of P. scandens leaf extract, which has the best anti-inflammatory effect, is 150mg/200g BW.
In Vitro Free Radical Scavenging Activity of Lagerstroemia speciosa PERS leaves on 1,1-diphenyl-2-picrylhydrazyl Rezqiyana, Gita Anna; Rijai, Laode
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 1 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/2y5gxp24

Abstract

This study aims to determine the yields and free radical scavenging activity based on IC50 value of the extract and the fraction of Lagerstroemia speciosa Pers leaves. The leaves of L. speciosa were macerated using 96% methanol and then practioned using different kinds of solvent based on its polarity including n-hexane, ethyl acetate, and n-butanol. The result showed that the yield of methanol extract obtained from L. speciosa levaes was 5.45% of dried samples obtained, the fraction of n-hexane 19.12%, the fraction of ethyl acetate 4,7%, and the fraction of n-butanol 1.93%. Testing of antioxidant activity is performed with the 1,1-Diphenyl-2- Picryl Hydrazyl (DPPH) by spectrophotometry UV-Visible. Absorbanse measurement was conducted with spectrophotometry at the wave lenght of 516 nm. Data was analyzed with linear regresion to obtain value of IC50. The result of research showed that the extract and fractions of L. speciosa leaves have activity as an antioxidant with the IC50 value of methanolic extract L. speciosa leaves was 12.5 ppm, n-hexane fraction was 18.75 ppm, ethyl acetate fraction was 21.87 ppm, n-butanol was 8.37 ppm.
Activity antibacterial from honey kelulut (Trigona sp.) against bacteria Staphylococcus epidermidis Sita, Annisa Aulia; Rijai, Laode; Rija'i, Hifdzur Rashif
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 2 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/0a3qnh10

Abstract

Honey kelulut is derived from the kelulut bee (Trigona sp.), which is native to Kalimantan and belongs to the Trigona genus of stingless bees. The honey produced by the Trigona genus has a well-documented antibacterial property. Study objective accomplished. This text discusses the potent antibacterial action of kelulut honey. The antibacterial testing method employed is the well diffusion method, utilizing the bacterium Staphylococcus epidermidis as the test organism. An antibacterial test was conducted by measuring the diameter of the zone of inhibition against bacteria. The results were obtained from concentrations of 40%, 60%, 80%, and 100%. Then the resistance diameter was measured for each concentration. The most optimal outcomes were achieved in the antibacterial test using honey kelulut. The honey kelulut with an 80% concentration exhibited a medium resistance level of 10.2 mm, while the 100% concentration demonstrated a strong resistance level of 13.7 mm.
Co-Authors Agus Setiawaty Almeida, Maria Amanda, Rezti Anggreini, Putri Arifian, Hanggara Arifuddin, M Arifuddin, Muhammad Arum, Alvionita Puspa Badawi, Satriani Baso Didik Hikmawan Bone, Mahfuzun Bulan, Adisty Sindi Daniel Happy Putra Fadhil, Andi Raihan Fahrul Rozi Farah Erika Farah, Harra Ismi Febrina, Lizma Herliani Herliani Herman Herman Herman Hernawati, Desy Hikmawan, Baso Didik Ibrahim, Arsyik Islamudin Ahmad Islamudin Ahmad Jeremia Giawa, Agusto Junaidin, Junaidin Kadir, Nurdianah Abdul Kama Tasawa, Gymnastiyar Lestari, Wahyu Yunita M. Arifuddin, M. Mohd Azlan Nafiah, Mohd Azlan Muhammad Faisal Mus, Nurul Muhlisa Olivia Siregar, Vita Purwita Sari, Regina Rahmadani, Agung Ramadhan, M. Rahmad Rashif Rijai, Hifdzur Rezky Khairun Nisaa, Nur Rezqiyana, Gita Anna Ridhotulloh, Yusuf Isro Rija'i, Hifdzur Rashif Rijai, Hifdzur Rashif Rija’i, Hifdzur Rashif RIKI RIKI, RIKI Rusli, Rolan Rusman, Arman Salam, Supriatno Samsul, Erwin Saputri, Mitha Sinthary, Venna Sita, Annisa Aulia Siti Hardiyanti Sugeng, Santoso Sukemi Sukemi Supriatno Tasya, Indriana Usman Usman Wirhanuddin, Wirhanuddin Yazid, Muhammad Ilfan