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All Journal HAYATI Journal of Biosciences Jurnal Ilmu Pertanian Indonesia ACTA VETERINARIA INDONESIANA Jurnal Sain Veteriner Saintek Perikanan : Indonesian Journal of Fisheries Science and Technology BIOTROPIA - The Southeast Asian Journal of Tropical Biology BERITA BIOLOGI Omni-Akuatika ARSHI Veterinary Letters Jurnal Abdimas ADPI Sains dan Teknologi Jurnal Agronomika Jurnal Medika Veterinaria
Damiana Rita Ekastuti
Institut Pertanian Bogor
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Environmental Science Immunology & microbiology Medicine & Pharmacology Veterinary

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TINJAUAN FISIOLOGIS DOMESTIKASI ULAT SUTERA LIAR Attacus atlas (Lepidoptera: Saturniidae) Damiana Rita Ekastuti
BERITA BIOLOGI Vol 11, No 2 (2012)
Publisher : Research Center for Biology-Indonesian Institute of Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14203/beritabiologi.v11i2.483

Abstract

Attacus atlas are insects producing silk materials having high economic value. It lives from South East Asia, almost all Indonesia until Australia.The demand of silk from Attacus atlas is quite high (10 tons/month). The A. atlas silk is very exclusive, with permanent in variety colors from light to dark brown. At present, to response the high demand, the people get cocoons from nature. This action could reduce result, and the scarcity of the insect. Beside that, rearing was done by placing the larvae on the trees (outdoor rearing). The outdoor rearing resulted in high mortality because of predators or stress. Better rearing is conducted by indoor rearing, that resulted in high survival rate, and high cocoon or egg production. It is because indoor rearing was supported in better environmental condition than outdoor condition that support physiological process eficiently.
Pelatihan Masyarakat Lingkar Kampus: Kualitas dan Kuantitas Telur Burung Puyuh Yang Mengalami Cekaman Koekoeh Santoso; Athirah Rerana Fitrianthy; Aryani Sismin Satyaningtijas; Damiana Rita Ekastuti; Isdoni Isdoni; Maharani Salsabila
Jurnal Abdimas ADPI Sains dan Teknologi Vol. 2 No. 4 (2021): Jurnal Abdimas ADPI Sains dan Teknologi
Publisher : Asosiasi Dosen Pengabdian kepada Masyarakat Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47841/saintek.v2i4.168

Abstract

Global warming has caused heat stress in quail (Coturnix coturnix Japonica). Heat stress can cause an increase in free radicals, through increased production and secretion of glucocorticoid hormones, which exceed the ability of the body's antioxidant system, causing oxidation, especially of double bonded lipid compounds found in cell membranes. Long-term secretion of glucocorticoids can cause a decrease in reproductive function. Dexamethasone is a glucocorticoid drug. The purpose of this study was to determine the effect of giving dexamethasone, as an analogy to glucocorticoid secretion in quail, on the quantity and quality of eggs produced by quail. Egg quality observed was length, width, weight, yolk weight and percentage, Haugh unit, white weight and percent, white height, egg shell weight and thickness. This study used 16 quails which were divided into four groups, namely one control group and three dexamethasone groups. The doses of dexamethasone given were 1.25 mg/kg BW, 2.5 mg/kg BW, and 5 mg/kg BW. Dexamethasone was given orally for two weeks. Sampling was carried out every day since the start of the study. The results showed that the administration of dexamethasone caused a decrease in the quantity and quality of eggs produced by quail.
PEMANFAATAN KURKUMIN DAN CAHAYA MONOKROMATIK DALAM MENINGKATKAN PERFORMA PRODUKSI DAN MUTU TELUR ITIK LOKAL Kasiyati Sumiati Damiana Rita Ekastuti, Wasmen Manalu
AGRONOMIKA Vol 12 No 02 (2017): AGRONOMIKA Vol. 12 No. 2 Agustus 2017 – Januari 2018
Publisher : Universitas Islam Batik Surakarta

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Abstract

Tujuan dari penelitian ini adalah memperbaiki potensi produksi dan mutu telur itik lokal sehingga mendukung produksi telur berkelanjutan melalui suplementasi kurkumin dan pemberian cahaya monokromatik artifisial. Penelitian ini menggunakan seratus empat puluh empat ekor itik magelang betina dengan rancangan acak lengkap pola faktorial 4x4 dengan 3 ulangan dan setiap ulangan menggunakan 3 ekor itik magelang betina. Faktor pertama adalah dosis kurkumin yang terdiri atas 4 level, yaitu 0, 9, 18, dan 36 mg/ekor/hari. Faktor kedua adalah warna cahaya monokromatik yang terdiri atas 4 level, yaitu putih, merah, hijau, dan biru. Hasil penelitian menunjukan bobot badan dewasa kelamin lebih tinggi 9.42 dan 6.89% (P<0.05), masing-masing pada cahaya merah dan hijau dibandingkan dengan cahaya putih. Umur dewasa kelamin lebih lambat sekitar 7.0, 13.72, dan 5.32 hari pada dosis 36 mg/ekor/hari, secara berurutan pada cahaya putih, hijau, dan biru dibandingkan dengan kontrol pada warna cahaya yang sama. Produksi telur duckday paling tinggi terdapat pada dosis 9mg/ekor/hari pada cahaya biru dan 36 mg/ekor/hari pada cahaya putih. Nilai HU yang dihasilkan pada penelitian ini dikategorikan AA, dengan skor warna kuning telur meningkat pada dosis 9, 18, dan 36 mg/ekor/hari.Kesimpulan dari penelitian ini adalah penggunaan cahaya merah, hijau, dan biru dapat meningkatkan bobot badan dewasa kelamin yang disertai dengan peningkatan produksi telur selama delapan minggu pada kombinasi dosis 9 mg/ekor/hari dengan cahaya biru dan dosis 36 mg/ekor/hari pada cahaya putih. Telur yang dihasilkan bermutu baik dan tidak mengalami perubahan
6. Erythrocyte Profile of Male Piglet Aged 31-Day Old (Sus scrofa domestica) in the Laboratory Animal Management Unit IPB University Gunanti Gunanti; Damiana Rita Ekastuti; Dwi Utari Rahmiati; Muhammad Fajrul Falah; Erwin Erwin
Jurnal Medika Veterinaria Vol 15, No 1 (2021): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v15i1.22130

Abstract

Domestic pig (Sus scrofa domestica) is well known as animal that used frequently as a research animal due to their similarity to human both in  terms of anatomy and physiology. Information regarding  standard value of domestic piglet’s hematology in Indonesia are still limited. The aim of this study was to obtain erythrocyte profiles of domestic piglets in Animal Laboratory and Research Unit, Bogor Agricultural University. The results of this study are expected to be used as an erythrocyte profiles reference of domestic piglets in Indonesia. Blood samples were collected from six male piglets in Animal Laboratory and Research Unit, Bogor Agricultural University through auricular vein, then the samples were put into a vaccuum tube containing anticoagulant (K3EDTA) for further test using hematology analyzer. The parameters used in this study consist of erythrocyte count, hemoglobin concentration, hematocrit, and erythrocyte indices. Data were analyzed descriptively in the form of mean ± standard deviation (minimum–maximum). The results of this study showed that the average of erythrocyte counts were 6,42 ± 1,03 millions/µL with 8,30 ± 1,51 g/dl hemoglobin concentration, hematocrite 29,80 ± 5,10%, MCV 46,47 ± 1,62 fL, MCH 12,83 ± 0, 65 pg, MCHC 27,75 ± 0,71 g/dL, and RDW 28,87 ± 3,86%.
Effects of Physalis angulata Leaf Extract on Female Reproductive Organs Following Busulfan Injection in Rats Satyaningtijas, Aryani; Ekastuti, Damiana Rita; Tarigan, Ronald; Prasetyaningtyas, Wahono Esthi; Adnyane, I Ketut Mudite; Mohamad, Kusdiantoro; Rahmadhani, Elsi; Sulistyana, Yanti; Mahendra, Arindina
HAYATI Journal of Biosciences Vol. 33 No. 2 (2026): March 2026
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.33.2.490-498

Abstract

Physalis angulata L. (ciplukan) is traditionally used as an herbal remedy with anticancer and antioxidant properties. At the same time, busulfan, a chemotherapy alkylating agent, causes gonadotoxicity and oxidative stress that impair female reproduction. This study aimed to evaluate the effect of P. angulata on reproductive function after busulfan administration in female rats. Twenty-five 6-week-old female rats were randomly divided into: Group I (control), Group II (busulfan only), Group III (P. angulata only), Group IV (busulfan followed by P. angulata after 14 days), and Group V (busulfan and P. angulata administered for 28 days). FSHR and LHR expression in the ovaries and MDA levels in the ovaries and uterus were measured to assess reproductive changes. Busulfan showed no significant effect on FSHR and LHR, whereas P. angulata induced downregulation, suggesting a potential negative feedback mechanism on ovarian receptors. Ovarian MDA showed a decreasing trend with combined treatments, while uterine MDA peaked after busulfan but declined markedly with P. angulata, indicating its role in alleviating oxidative stress. In conclusion, P. angulata may modulate hormonal balance in rat ovaries and decrease oxidative stress in the uterus after busulfan treatment.
HEPATOPROTECTIVE EFFECT OF Physalis angulata L. LEAF ETHANOL EXTRACT AGAINST BUSULFAN-INDUCED LIVER DAMAGE IN FEMALE RATS Elsi Rahmadhani; Aryani Sismin Satyaningtijas; Damiana Rita Ekastuti; Ronald Tarigan; I Ketut Mudite Adnyane; Kusdiantoro Mohamad; Wahono Esthi Prasetyaningtyas; Yanti Sulistyana
BIOTROPIA Vol. 33 No. 3 (2026): BIOTROPIA Vol. 33 No. 3 September 2026
Publisher : SEAMEO BIOTROP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11598/btb.2026.33.3.2588

Abstract

ARTICLE HIGLIGHTSBusulfan can damage the liver by triggering oxidative stress Physalis angulata leaves show natural liver protective effects Extract reduced oxidative damage in liver tissue Liver structure improved after extract treatment Early treatment provided stronger liver protection than delayed useABSTRACTLiver disease is the leading cause of death worldwide, with drug-induced hepatotoxicity representing a major contributing factor. Busulfan, an anticancer drug used in chronic myeloid leukemia, is cytotoxic to proliferating cells and can induce liver injury. Physalis angulata L. (ground cherry) contains bioactive compounds with potential hepatoprotective properties. This study aimed to evaluate the protective effects of ethanol extract of Phyasalis angulata L. (EEPA) leaves on busulfan-induced liver damage in female Sprague–Dawley rats. Twenty-five rats were randomly divided into five groups: P1 (normal control), P2 (busulfan 40 mg/kg BW, single dose), P3 (extract 300 mg/kg BW, days 1–28), P4 (busulfan + extract, days 1–28), and P5 (busulfan + extract, days 14–28). Parameters assessed were alanine aminotransferase (ALT) and aspartate aminotransferase (AST), the level of malondialdehyde (MDA) in liver, and liver histology. Data were analyzed using one-way analysis of variance (ANOVA) followed by a post hoc test. The results showed that Physalis angulata L. extract did not cause significant differences in the serum ALT and AST levels but significantly reduced the MDA concentrations and improved the liver histological architecture. Busulfan administration significantly decreased hepatocyte count and increased Kupffer and inflammatory cells, fatty degeneration, and necrosis. Early administration of the extract (P4) demonstrated stronger hepatoprotective effects compared with delayed administration (P5). These findings suggest that EEPA leaves exerts hepatoprotective effects against busulfan-induced liver injury in rats, likely through antioxidant activity, as evidenced by subsequent histological improvement, and highlighting its potential as a natural hepatoprotective agent.
Profil eritrosit, hemoglobin, dan nilai hematokrit luwak Jawa (Paradoxurus hemaphroditus) pemakan dan tidak pemakan buah kopi Elsi Rahmadhani; I Wayan Teguh Wibawan; Damiana Rita Ekastuti; Ronald Tarigan; Pudji Achmadi; Isdoni Isdoni; Koekoeh Santoso; Aryani Satyaningtijas
ARSHI Veterinary Letters Vol. 7 No. 1 (2023): ARSHI Veterinary Letters - Februari 2023
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.7.1.15-16

Abstract

Luwak Jawa (Paradoxurus hemaphroditus) merupakan hewan yang memiliki kemampuan menghasilkan biji kopi yang berkualitas, sehingga status kesehatannya perlu untuk diperhatikan. Gambaran darah dapat dijadikan sebagai indikator status kesehatan luwak pada kondisi tertentu. Penelitian mengenai luwak telah banyak dilaporkan, namun belum ada penelitian mengenai parameter fisiologis khususnya profil eritrosit dari luwak yang sengaja diberikan buah kopi secara terus menerus selama 3 bulan. Penelitian ini bertujuan untuk menghitung profil eritrosit pada luwak Jawa pemakan pemakan kopi dan tidak pemakan buah kopi. Gambaran darah luwak Jawa pada saat adaptasi dan pemeliharaan berfluktuasi. Rataan jumlah eritrosit luwak pemakan buah kopi dan tidak pemakan buah kopi adalah (8,24±2,40) x 106/mL dan (8,25±2,16) x 106/mL, kadar hemoglobin adalah (6,18±2,21) g/dL dan (6,40±2,21) g/dL dan nilai hematokrit adalah (16,50±2,21) % dan (16,00±2,14) %. Secara umum gambaran darah luwak Jawa pemakan buah kopi memiliki rataan yang lebih rendah dari pada luwak Jawa yang tidak diberi buah kopi.
Pemendekan waktu siklus estrus pada luwak Jawa (Paradoxurus hermaphroditus) terdeteksi melalui metode ulas vagina Nelda Fliza Zora; Mokhamad Fakhrul Ulum; Damiana Rita Ekastuti; Ronald Tarigan; Pudji Achmadi; Isdoni Bustaman; Koekoeh Santoso; Hera Maheshwari; Agik Suprayogi; Wasmen Manalu; Aryani Satyaningtijas
ARSHI Veterinary Letters Vol. 7 No. 2 (2023): ARSHI Veterinary Letters - Mei 2023
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.7.2.35-36

Abstract

Luwak Jawa (Paradoxurus hermaphroditus) merupakan salah satu hewan liar yang dapat dimanfaatkan sebagai penyeleksi biji kopi untuk menghasilkan kopi berkualitas dan bernilai ekonomis tinggi. Pemeliharaan yang tidak sesuai dapat memengaruhi kondisi fisiologis dan reproduksi luwak sehingga penting untuk diketahui sebagai dasar manajemen pemeliharaan dan kesehatan untuk optimalisasi produksi, pencegahan penyakit, dan konservasi luwak. Pemantauan ini bertujuan untuk mengetahui panjang waktu total siklus estrus dan waktu dari setiap fase estrus yaitu fase proestrus, estrus, metestrus dan diestrus. Luwak Jawa dari diperoleh dari pasar hewan sebanyak 2 ekor berjenis kelamin betina dengan bobot badan sekitar 4 kg diambil data ulas vagina selama 21 hari pada pagi dan sore hari. Sel epitel vagina diperiksa di bawah mikroskop dan dianalisa secara kuantitatif. Hasil pengamatan menunjukkan pemendekan siklus estrus dengan panjang total siklus estrus yaitu 121,5±7,5 jam (5 hari). Durasi waktu proestrus 12,0±0,0 jam, estrus 22,5±3,0 jam, metestrus 25,5±3,0 jam dan diestrus 61,5±3,0 jam.
Kadar kolesterol dan glukosa darah luwak Jawa (Paradoxurus hermaphroditus) yang didomestikasi Ira Agustina Dewi Gandasari; Damiana Rita Ekastuti; Ronald Tarigan; Pudji Achmadi; Isdoni Bustaman; Koekoeh Santoso; Hera Maheshwari; Agik Suprayogi; Wasmen Manalu; Aryani Satyaningtijas
ARSHI Veterinary Letters Vol. 7 No. 1 (2023): ARSHI Veterinary Letters - Februari 2023
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.7.1.19-20

Abstract

Status kesehatan luwak yang pemanfaatannya cukup tinggi sebagai penghasil kopi belum banyak dipelajari secara lengkap. Informasi mengenai status fisiologis luwak Jawa (Paradoxurus hermaphroditus) yang telah didomestikasi masih terbatas dan sangat diperlukan untuk menilai aspek kesejahteran hewan di penangkaran. Studi ini melaporkan kadar kimia darah dan kolesterol luwak Jawa yang sudah didomestikasi. Luwak dalam penelitian ini diberi pakan berupa pisang, kepala ayam dan juga dog food. Pemeriksaan kimia darah berupa kadar glukosa dan kolesterol darah dilakukan terhadap 6 ekor luwak yang diberi pakan pisang, kepala ayam dan juga dog food. Hasil menunjukkan bahwa luwak Jawa jantan memiliki kadar glukosa sebesar 68,00±22,55 mg/dL dan luwak Jawa betina yaitu sebesar 73,78±12,60 mg/dL. Kadar kolesterol darah pada luwak Jawa jantan yaitu sebesar 145,78±22,29 mg/dL dan luwak Jawa betina yaitu sebesar 142,00±12,44 mg/dL.
Penanganan spectacular dysecdysis pada seekor ular Boa constrictor di Lombok Wildlife Park, Nusa Tenggara Barat Fadhila Satvika; Gilang Kala Maulana; Aryani Sismin Satyaningtijas; Damiana Rita Ekastuti; Hera Maheshwari; Koekoeh Santoso; Ronald Tarigan; Pudji Achmadi; Isdoni Bustamam
ARSHI Veterinary Letters Vol. 7 No. 4 (2023): ARSHI Veterinary Letters - November 2023
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.7.4.67-68

Abstract

Lombok Wildlife Park merupakan lembaga konservasi yang berada di Lombok, Nusa Tenggara Barat dengan salah satu satwa liar yang ditangani adalah ular. Tulisan ini melaporkan penanganan spectacular dysecdysis pada seekor ular boa (Boa constrictor). Ular bernama Boly, berumur sekitar 1.5 tahun dengan bobot badan 8 ons mengalami eye caps stuck atau spectacular dysecdysis setelah proses pergantian kulit yang tidak sempurna. Terjadi kebengkakan pada jaringan di kedua mata dan boa kehilangan nafsu makan. Pengobatan dilakukan dengan pemberian antibiotik dan anti inflamasi untuk 3 hari pertama dan dilanjutkan dengan supplemen pendukung berupa zat besi dan vitamin B12 intramuskular selama 3 hari berikutnya. Jaringan bengkak pada mata kiri pecah dan menyebabkan kerusakan pada organ mata, sedangkan jaringan yang telah mengering pada mata kanan dikelupas secara manual. Nafsu makan ular sudah kembali membaik dan sudah mau makan dengan sendirinya.
Co-Authors . Santoso A.S. Satyaningtijas Ade Sunarma Ade Sunarma Agik Suprayogi Agus Oman Sudrajat Agustin Indrawati Anita Esfandiari Aris Kumaidi Aryani Satyaningtijas Athirah Rerana Fitrianthy Azizatul Ulfa Bahri Syamsuryadi Chairun Nisa Cut Dara Dewi Dwi Utari Rahmiati Elsi Rahmadhani Elsi Rahmadhani Erdina Pangestika Erwin Erwin Fadhila Satvika Fatimatus Sa’diyah Putri Fitri Dinar Rahayu Friska Mery Montolalu Gilang Kala Maulana Gilang Kala Maulana Gunanti . Helny Rosita Supriadi HERA MAHESHWARI Huda Shalahudin Darusman I wayan Teguh Wibawan Ice Lusia Marta Ira Agustina Dewi Gandasari Irfan Nurhidayat Irma Isnafia Arief Isdoni Bustamam Isdoni Bustaman Ketut Adnyane Mudite Koekoeh Santoso koekoeh santoso Koekoeh Santoso Koekoeh Santoso Koekoeh Santoso Kusdiantoro Mohamad La Jumadin Livana Dethris Rawung Lynette Ong Huey M. Zairin Junior Maharani Salsabila Mahendra, Arindina Mahmud, Andi Tenri Bau Astuti Maritrana Putri Masaji Washio Maulana Sydik Mohamad Yogie Hendrawan Mokhamad Fakhrul Ulum, Mokhamad Muh Alwi Amnur Muhammad Fajrul Falah Nelda Fliza Zora Pudji Achmadi R. Iis Arifiantini Rahmadhani, Elsi Rahminiwati, Min Reinilda Alwina Resi Milna Risa Tiuria Ronald Tarigan Ronald Tarigan Ronald Tarigan Ronald Tarigan Rudi Afnan Sattabongkoch Maneewong Srihadi Agungpriyono Sulistyana, Yanti Tarigan, Ronald Tutik Wresdiyati Umi Cahyaningsih Wahono Esthi Prasetyaningtyas Wahyu Sri Wulandari Wasmen Manalu Yanti Sulistyana Yuvensius Yuvensius Zulvia Maika Letis