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All Journal Jurnal Kesehatan Lingkungan indonesia Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Kesehatan Prima INTEK: Jurnal Penelitian Medical Laboratory Analysis and Sciences Journal Budimas : Jurnal Pengabdian Masyarakat Jurnal teknologi Kesehatan Borneo Jurnal Kebidanan Khatulistiwa Jakiyah : Jurnal Ilmiah Umum dan Kesehatan Aisyiyah Jurnal Vokasi Kesehatan Jurnal Laboratorium Khatulistiwa Indonesian Journal of Community Empowerment Jurnal Sains, Teknologi dan Kesehatan MEDICA (International Medical Scientific Journal) ELECTRON (Journal of Science and Technology)
Maulidiyah Salim
Poltekkes Kemenkes Pontianak
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The Effect of Giving Forest Guava Fruit Yogurt (Bellucia pentamera Naudin) on the Growth of Esterichia coli Bacteria in Mice (Mus musculus) Agusanty, Shelly Festilia; Salim, Maulidiyah; Chitra, Fara
Jurnal Penelitian Pendidikan IPA Vol 11 No 2 (2025): February
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i2.9077

Abstract

This research investigates the effect of forest guava fruit yogurt (Bellucia pentamera Naudin) on the growth of Escherichia coli bacteria in mice (Mus musculus). The study utilized an experimental design with treatment and control groups. Mice were divided into four groups: three treatment groups received forest guava fruit yogurt at concentrations of 5, 10, and 15%, respectively, administered at 0.5 ml per dose daily for 14 days, while the control group was given plain yogurt. E. coli growth was assessed by analyzing fecal samples from each group. The findings revealed that the growth of E. coli bacteria in the mice decreased significantly after administration of forest guava fruit yogurt, with the most pronounced reduction observed in the group receiving the 15% concentration. In contrast, the control group, which received plain yogurt, exhibited a less marked decrease in E. coli growth. These results suggest that forest guava fruit yogurt has a stronger inhibitory effect on E. coli bacteria compared to plain yogurt. In conclusion, forest guava fruit yogurt appears to be an effective natural agent for reducing E. coli growth in mice, potentially offering added health benefits beyond those of conventional yogurt.
Anti-Inflammatory Activity Test of Tapak Liman (Elephantopus scaber L.) Leaf Extract Using Red Blood Cell Membrane Stabilization Method Wahdaniah, Wahdaniah; Yanti, Rahmi; Kamilla, Laila; Salim, Maulidiyah
Jurnal Laboratorium Khatulistiwa Vol 9, No 1 (2025): November 2025
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v9i1.2135

Abstract

Inflammation is the reaction of living tissue to trauma or infection, both in acute and chronic conditions. One plant with anti-inflammatory potential is the tapak liman leaf (Elephantopus scamber L.), which contains secondary metabolites such as phenolics, flavonoids, tannins, alkaloids, steroids/treponoids, and saponins. The purpose of this study was to determine the anti-inflammatory activity of Elephantopus scamber L. leaf extract at concentrations of 0.005%, 0.01%, 0.02%, 0.04%, and 0.08% using the red blood cell membrane stability method. Anti-inflammatory activity showed that 70% ethanol extract of tapak liman leaves had low anti-inflammatory activity at a concentration of 0.005% with a stability of 98.00%, while the highest activity was found at a concentration of 0.08% with a stability of 99.65%. Microscopic examination showed that at concentrations of 0.005%, 0.01%, 0.02%, 0.04%, and 0.08%, the administration of tapak liman extract could restore the normal shape of erythrocytes. The Kruskal-Wallis test yielded a significance value of 0.000, which is less than 0.05, meaning that Ha is accepted. It can be concluded that there are differences in the anti-inflammatory activity of tapak liman leaf extract (Elephantopus scamber L.) at concentrations of 0.005%, 0.01%, 0.02%, 0.04%, and 0.08%.
Co-Authors Afni, Adisty Agusanty, Shelly Festilia Agustriana, Fadhila Anisa Fitri Midani Ari Nuswantoro Ari Widiyantoro Chitra, Fara Daratista, Ayu Dinasti Aprillia Dj, Herlinda Djohan Djohan, Herlinda Eka Aprilianti Aprilianti Emy Yulianti, Emy Etiek Nurhayati Gestiwana, Oksa Hadjpi Rona Dinihari Handayani, Vitria Wuri Herlinda Djohan Ihsan, Bagus Muhammad Indrawati, Ratih Indrawati, Ratih Jajar Pramata Syari Jajar Pramata Syari Laila Kamila Laila Kamila Laila Kamilah Laila Kamilla Laila Kamilla Lia, Sestriana Linda Triana Linda Triana Muhammad Ihsan, Bagus Novia Wahyu Lestari Nur Endah Wahyuningsih Nurhayati, Etiek Pratama, Victorinus Alfino Pusaka, Semerdanta Ratika, Meila Ratnawaty, Gervacia Jenny Reinisya Irine Sadid, Randy Sari, Emilda Selvianty, Selvianty Sestriana Lia Slamet Sri Tumpuk Sutriswanto, Sutriswanto Suwono Suwono Tessa Siswina Tumpuk, Sri Utin Siti Candra Sari Victorinus Alfino Pratama Wahdaniah Wahdaniah Wahdaniah Wahyudi YANTI, RAHMI Yunus, Mohd