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Diabetic Foot Ulcers: Impact on Quality of Life and Instruments for Its Measurement Qomariyanti, Khairunisa; Sauriasari, Rani; Sartika, Ratu Ayu Dewi
Borneo Journal of Pharmacy Vol. 7 No. 2 (2024): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v7i2.6554

Abstract

Diabetic foot ulcers (DFUs) are a major complication of diabetes mellitus, significantly impacting patients' quality of life (QoL) due to the heightened risk of infection and amputation. Pharmacists play a crucial role in managing diabetes and its complications, and assessing QoL can be a valuable tool for monitoring treatment success and medication effectiveness. This review explores instruments used to measure QoL in patients with DFUs, encompassing both general and disease-specific tools. We examine the impact of DFUs on QoL and discuss various theoretical frameworks used to understand this complex relationship.
Hubungan Kebiasaan Minum Kopi dan Minuman Sumber Kafein terhadap Tekanan Darah Pasien Hipertensi Berdasarkan Jenis Kelamin di Puskesmas Kemiri Muka, Kota Depok Chodijah, Siti; Utari, Diah Mulyawati; Sartika, Ratu Ayu Dewi; Putri, Primastri Nuryandari
Malahayati Nursing Journal Vol 7, No 5 (2025): Volume 7 Nomor 5 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v7i5.19958

Abstract

ABSTRACT Hypertension is the leading cause of death worldwide. Factors that influence the incidence of hypertension are age, lack of physical activity and unhealthy diet. This study aims to determine the relationship of coffee drinking habitsand caffeine source drinks to blood pressure in hypertensive patients based on gender at Kemiri Muka Health Center, Depok. The research design was cross sectional with a sample size of 156 respondents. The population is 18 years old and above who live in the working area of Kemiri Muka Health Center, Depok City. Chi Square test results showed a significant relationship between coffee consumption (P = 0.021), and caffeine source drinks (coffee, tea, soft drinks) (P = 0.008) with blood pressure of hypertensive men. Logistic regression results showed that caffeine consumptionwas 32 times (OR=32,000) more likely to cause uncontrolled blood pressure in hypertensive men after being controlled by coffee consumption. While in hypertensive women aged ≥60 years was 1,8 times higher (OR=1.893) uncontrolled blood pressure after being controlled by education and moderate physical activity. Preventive effortsare needed, especially in men regarding the consumption of coffee and caffeine-source beverages, as well as educating the public regarding the management of hypertension risk factors. Keywords: Hypertension, Coffee, Caffeine Source Beverages, Age  ABSTRAK Hipertensi merupakan penyebab utama kematian diseluruh dunia. Faktor yang mempengaruhi kejadian hipertensi adalah usia, kurangnya aktivitas fisik dan pola makan yang tidak sehat. Penelitian ini bertujuan untuk mengetahui hubungan karakteristik responden (jenis kelamin, usia, status pekerjaan, tingkat pendidikan), aktivitas fisik, kebiasaan minum kopi dan minuman sumber kafein terhadap tekanan darah pada pasien hipertensi berdasarkan jenis kelamin di Puskesmas Kemiri Muka, Depok. Desain penelitian adalah cross sectional dengan jumlah sampel sebanyak 156 responden. Populasinya adalah usia 18 tahun keatas yang tinggal di wilayah kerja Puskesmas Kemiri Muka, Kota Depok. Hasil uji Chi Square menunjukkan ada hubungan yang signifikan antara konsumsi kopi (P= 0.021), dan minuman sumber kafein (kopi, teh, soft drink) (P= 0.008) dengan tekanan darah laki-laki hipertensi. Hasil regresi logistikmenunjukkan konsumsi minuman sumber kafein terbukti berisiko 32 kali (OR=32,000) menyebabkan tekanan darah tidak terkendali pada laki-laki hipertensi setelah di kontol oleh konsumsi kopi, sedangkan pada perempuan hipertensi usia ≥60 tahun berisiko 1,8 kali (OR=1,893) mengalami tekanan darah tidak terkendali setelah di kontrol oleh, pendidikan dan aktivitas fisik sedang. Perlu adanya upaya preventif terutama pada pria mengenai konsumsi kopi dan minuman sumber kafein, serta mengedukasi masyarakat mengenai pengelolaan faktor risiko hipertensi. Kata Kunci: Hipertensi, Kopi, Minuman Sumber Kafein, Usia
Efficacy and Safety of Glibenclamide Compared with Insulin in Gestational Diabetes Mellitus: A Systematic Review and Meta-analysis Haifa, Alifia Fauziyyah; Qomariyanti, Khairunnisa; Sartika, Ratu Ayu Dewi; Sauriasari, Rani
Pharmaceutical Sciences and Research Vol. 12, No. 2
Publisher : UI Scholars Hub

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Abstract

Gestational diabetes mellitus (GDM) is a prevalent pregnancy complication associated with an increased risk of maternal and neonatal complications compared with non-diabetic pregnancies. Pharmacological treatments, such as glibenclamide, are expected to provide optimal glycemic control and reduce these risks. However, concerns regarding its safety persist and some regulatory agencies have not approved glibenclamide for GDM treatment. This systematic review and meta-analysis aimed to synthesize the most recent evidence on the efficacy and safety of glibenclamide compared with insulin in the management of GDM, with a focus on maternal and neonatal outcomes based on the most recent RCT. The objective is to provide updated insight and strengthen the evidence based supporting the use of glibenclamide as treatment option for GDM. Relevant studies were identified from Pubmed, Scopus, and CENTRAL databases, resulting in 11 randomized controlled trials (RCTs) involving 2,019 participants. The pooled analysis found that glibenclamide significantly increases the risk of neonatal hypoglycemia [RR 1.65; 95% CI 1.23 to 2.22; p-value 0.0009] and significantly decreases the risk of neonatal respiratory distress syndrome (NRDS) [RR 0.56; 95% CI 0.33 to 0.95; p-value 0.03], compared to insulin. No significant differences were observed in other maternal and neonatal outcomes between the two treatments. In conclusion, glibenclamide demonstrated comparable efficacy and safety to insulin in the management of GDM, making it a viable treatment option alongside insulin.
Cadres’ role in Posyandu revitalization as stunting early detection in Babakan Madang Sub-District, Bogor District Rahmawati, Nurul Dina; Sartika, Ratu Ayu Dewi
ASEAN Journal of Community Engagement Vol. 4, No. 2
Publisher : UI Scholars Hub

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Abstract

Stunting, the inability to reach one's full potential, still remains common in Indonesia. As a result of stunting’s intergenerational consequences, many strategies have been conducted by both government and non-government organizations to tackle this issue, including nutrition-specific and sensitive interventions, with Integrated Health Service Post (Posyandu) revitalization as one of the key measures to provide valid, reliable, and up-to-date data to establish the early detection and management of stunting. Unfortunately, this role is sub-optimally performed due to the limited competence of the health volunteers (cadres) that correlates with the suppressed parents’ motivation to visit a Posyandu. Moreover, their difficulties are exaggerated by the weak reporting and supervising system. This study aimed to evaluate the cadres’ knowledge and practice change after a sequence of training to revitalize the Posyandu’s role. This quasi-experimental study involved treatment and control villages located in Babakan Madang Sub-District, Bogor District, from which 41 and 37 cadres participated, respectively: between August and November 2019. The treatment group received three consecutive months of structured training, which comprised different learning methods, namely, group discussions, role plays, games, and seminars about Posyandu and stunting management, maternal and child health, and nutritional assessment. The control group was only visited for observational activities. Changes in cadres’ knowledge and practices were collected using structured quantitative questionnaires and analysed using the Wilcoxon test. Both groups shared a considerably similar practice of Posyandu management, but a significant improvement in cadres’ knowledge was found in the intervention group after the training (p < 0.001) compared with the control group. Longer duration is needed to observe any behaviour change, as indicated by their practice of Posyandu management.
Translation and validation of the Indonesian version of the Family Support Scale (FSS) for elderly Kurniawan, Didi; Sahar, Junaiti; Rekawati, Etty; Sartika, Ratu Ayu Dewi
Lentera Perawat Vol. 6 No. 4 (2025): October - Desember
Publisher : STIKes Al-Ma'arif Baturaja

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52235/lp.v6i4.611

Abstract

Abstract Background: Family support is a crucial determinant of elderly wellbeing, influencing emotional stability, independence, and overall quality of life. The Family Support Scale (FSS) is widely used internationally to measure perceived family support; however, no standardized Indonesian version has been available for elderly populations. Objective: This study aimed to translate, culturally adapt, and evaluate the validity and reliability of the Family Support Scale (FSS) for Older People into the Indonesian language for use among the elderly. Methods: A methodological design was applied using a standardized back-translation procedure encompassing forward translation, synthesis, blind back-translation, and expert harmonization. Fifty elderly respondents aged ≥60 years in Pekanbaru were recruited to assess the instrument’s psychometric properties. Construct validity was evaluated through corrected item–total correlation, while reliability was measured using Cronbach’s Alpha. Results: All 20 items demonstrated acceptable corrected item–total correlation values (>0.30), indicating good construct validity. Reliability testing yielded a Cronbach’s Alpha of 0.949, reflecting excellent internal consistency. The translation and cultural adaptation process successfully preserved semantic, cultural, and conceptual equivalence with the original instrument. Conclusion: The Indonesian version of the FSS is valid and reliable for assessing perceived family support among the elderly in Indonesia. The instrument is suitable for use in clinical practice, community health assessments, and elderly-focused research. Future studies should include larger and more diverse samples and incorporate exploratory and confirmatory factor analyses to further strengthen the construct structure.