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Journal : International Journal of Public Health Science (IJPHS)

The synthesis of nanosilver and carbamat to control of Anopheles in malaria endemic areas Raharjo, Mursid; Subagio, Agus; Sulistiyani, Sulistiyani
International Journal of Public Health Science (IJPHS) Vol 13, No 1: March 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i1.23453

Abstract

Malaria is a national and global problem that really needs attention and Indonesia is the second highest country with the highest number of cases 304,607 in 2021. The use of insecticides at inappropriate doses causes resistance to targets. The aim of this study was to analyze the toxicity of silver nanoparticles to adult Anopheles mosquitoes in malaria endemic areas as well as to determine the lethal concentration (LC50) and to project effectiveness in the lifetime. This research is experimental and uses a post-treatment with control design which was carried out in 4 stages from 2019-2022, which includes laboratory scale tests (2019), field laboratory scale tests (2020), ecological endemic area scale tests (2021), and lifetime tests (2022). Calculation of LC50 in nanosilver toxicity 5965 mg/l and Calculation of life time projections produces the formula Y=(-) 0.012Ln(X)+0.6933. Absorption of silver nanoparticles into the bodies of Anopheles sp. occurs through the spiracles and attacks the Ache enzyme in the central nervous system thereby stopping the working system of the mosquito which will then die. Nanosilver is a very effective herbal insecticide used as an effort to control malaria cases in endemic areas with the right dose and method. For life time, a dose of 1500 mg/l nanosilver effectively kills 74% of adult Anopheles sp mosquitoes on day 32 and it is projected that on 1 year the efficacy of nanomaterials still has an efficacy of 62%).
Co-Authors Adi Darmawan Adithia, Rizky Putra Agung Cahyono Agus Setyawan Ahmad Aviv Mahmudi Alfatinnisa, Zalfa Andriyan, Mohammad Wahyu Anghistra, Pradipta Ditya Annisa Fadillah Antari, Arlita Leniseptaria Ari Udijono Aslam Fatkhudin Awal Prasetyo Bagoes Widjanarko Bayu Surarso Della Widya Puspita Ditalistya, Tabah Djalal Er Riyanto Dwi Sutiningsih Dwiantoro, Luky Edy Supriyanto Efiyanti, Lisa Eko Hidayanto Endah Puji Astuti, Endah Puji Eny Enawaty Erma Prihastanti Febio Dalanta Galih Priambodo, Galih Gufron, Ahmad Hadi Endrawati Halida Halida Hardhono Susanto Hella Arofah Hendri Widiyandari Hendri Widiyandari Hendri Widyandari Heri Sutanto Hermin Pancasakti Kusumaningrum Horasdia Saragih I Gusti Ngurah Antaryama I Nurhasanah Iis Nurhasanah Imam Misbach Indah Saraswati Indras Marhaendrajaya Indri Yuliastuti, Indri Jatmiko Endro Suseno Jaya, La Ode Irman Joko Sudarto Karimah, Putri Diah Wahyu Khasan Rowi Khasan Rowi M F Taftiari M. Imam Taufiq Maman Budiman Maman Budiman Marinu Waruwu Mashuri, Chamdan Mateus Sakundarno Adi, Mateus Sakundarno Maulidanir Rohman Mentari, Alfitra Akbar Bara Mentari Metri Setyaningsih Metri Setyaningsih Moch. Abdul Mukid Moehamad Barmawi Moehammad Barmawi Mohammad Muhriz Muckharom, Ahmad Ali Muhammad Fauzi Muhammad Iskandar Zulkarnain Muhammad Nur Muhammad Zainuri Mursid Raharjo Musni Ahyani Musni Ahyani, Musni Mustafid Mustafid Ngadiwiyana M.Si. S.Si. Ngurah Ayu Ketut Umiati Nissa Kusariana Pardoyo Pardoyo Pardoyo, Pepen Arifin Pepen Arifin Priyono Priyono Priyono, R Hidayatuloh R. Yudianti Redemtus Heru Tjahjana Rike Yudianti Rike Yudianti Rini Budihastuti Ririn Sulpiani Rizky Bimanda Sakti Romi Buana Puja Pangestu Saputra, Muhammad Ragil Satriyo Adhy Silviana Silviana Siti Nandiyah, Siti Skolastika Dara Sabatini Sri Eny Suharini, Sri Eny Sri Isdadiyanto Sri Widodo Agung Suedy Stefani Candra Firmanti Subhan Subhan Subhan, Sudarno Sudarno Sudarto, Joko Sukirno Sukirno Sukirno Sukirno SULISTIYANI SULISTIYANI Sunarno Sunarno Tatang Wahyudi Tatang Wahyudi, Tatang Taufiq, Heydar Ruffa Tri Windarti Udi Harmoko Vincensius Gunawan S.K. Weni Safitri Widianingsih Widianingsih Widiastuti Samekto Yani. T, Ahmad Yohana Maya Kartikaratri Yundari, Yundari Yuvita Muliastuti