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All Journal Jurnal Ilmu Pertanian Indonesia Jurnal Teknologi Industri Pertanian E-jurnal Agro-Industri Indonesia Forum Pasca Sarjana International Journal of Science and Engineering (IJSE) International Journal of Renewable Energy Development TEKNIK Teknotan: Jurnal Industri Teknologi Pertanian Jurnal Sains Materi Indonesia Microbiology Indonesia Majalah Kedokteran Bandung BIOTROPIA - The Southeast Asian Journal of Tropical Biology AL KAUNIYAH Jurnal Ilmiah Teknik Elektro Komputer dan Informatika (JITEKI) Agrointek Jurnal AgroBiogen Jurnal Penelitian Pascapanen Pertanian Jurnal Teknologi Pertanian Jurnal Pengelolaan Sumberdaya Alam dan Lingkungan (Journal of Natural Resources and Environmental Management) Jurnal Litbang Industri Science and Technology Indonesia Industria: Jurnal Teknologi dan Manajemen Agroindustri Jurnal Bioteknologi & Biosains Indonesia (JBBI) EnviroScienteae EDUFORTECH IJEMS (Indonesian Journal of Environmental Management and Sustainability) Seminar Nasional Lahan Suboptimal Menara Perkebunan Teknologi Indonesia STI Policy and Management Journal Jurnal Ilmu Kefarmasian Indonesia PERENNIAL Wood Research Journal : Journal of Indonesian Wood Research Society Wood Research Journal : Journal of Indonesian Wood Research Society Jurnal Litbang Industri Makara Journal of Science Makara Journal of Technology International Journal of Renewable Energy Development
Khaswar Syamsu
Department Of Agricultural Industrial Technology - Bogor Agricultural University Dramaga, Bogor, 16680
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Physics Public Health Veterinary Other

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Journal : AL KAUNIYAH

 1 
PENGARUH PENAMBAHAN DL-METIONIN DALAM MEDIA KULTIVASI TERHADAP PRODUKSI SEFALOSPORIN C DARI KAPANG Acremonium chrysogenum CB2/11/1 Eni Dwi Islamiati; Khaswar Syamsu; Erwahyuni E Prabandani
Al-Kauniyah: Jurnal Biologi Vol 10, No 1 (2017): Al-Kauniyah Jurnal Biologi
Publisher : Department of Biology, Faculty of Science and Technology, Syarif Hidayatullah State Islami

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (441.192 KB) | DOI: 10.15408/kauniyah.v10i1.3595

Abstract

Abstrak Sefalosporin merupakan antibiotik  β-laktam yang mempunyai efektivitas dalam melawan bakteri Gram positif dan negatif. Antibiotik ini dihasilkan oleh kapang Acremonium chrysogenum. Media kultivasi yang optimum dapat meningkatkan produksi sefalosporin. Komposisi media kultivasi yang paling berpengaruh adalah induser. Induser dapat meningkatkan produksi sefalosporin dari kapang A. chrysogenum. Penelitian ini bertujuan untuk melihat pengaruh metionin dalam media produksi sefalosporin dari kapang A. chrysogenum CB 2/11/1. Inokulum A.chrysogenum dibiakkan pada media kultivasi sefalosporin tanpa penambahan DL-metionin  dan  pada media kultivasi  dengan penambahan DL-metionin. Penentuan level konsentrasi DL-metionin dirancang menggunakan Rancangan Acak Lengkap 1 faktor pada tiap-tiap proses penentuan nutrisi. Data yang diperoleh dari masing-masing perlakuan dianalisis sidik ragam pada taraf nyata 5%. Hasil penelitian menunjukkan bahwa metionin sebagai induser dapat meningkatkan produksi sefalosporin sebesar 1,2 kali dibandingkan dengan media kultivasi yang tanpa menggunakan metionin. Pada pengujian level konsentrasi DL-metionin menunjukkan bahwa konsentrasi terbaik metionin adalah 0,4 g/L menghasilkan sefalosporin sebesar 3989 mg/L. Abstract Cephalosporins is a β-lactam antibiotic that has effectiveness against Gram-positive and negative bacteria. This antibiotic is produced by Acremonium chrysogenum. Optimum cultivation medium can increase the production of cephalosporins. The most influential cultivation medium composition is an inducer that increases production of cephalosporin from the fungi. The objective of this study was to investigate the influence of methionine in the cephalosporin production medium containing A. chrysogenum CB 2/11/1, with DL-methionine as the inducer. The inoculum was cultivated in the cultivation media containing cephalosporins without the addition of DL-metionin and in the media with the addition of DL-metionin. The result showed that the DL-methionine increased cephalosporins production 1.2 fold compared to those without using methionine. The assay on the concentration level of DL-methionine showed the best concentration methionine of 0.4 g/L produced cephalosporin by 3989 mg/L.
Co-Authors . Gunawan . Gunawan A. Aziz Darwis A. Herryandie Abdul Aziz Darwis Adhi Kusnadi Akhmad Endang Zainal Hasan Anas Miftah Fauzi Anggun Rahman Rahman Ani Suryani Ani Suryani Aninda Sekar ZAHRA Anwar Nur Anwar Nur Ardani Lukman ASEP RISWOKO ASTUTIATI NURHASANAH Bambang Prasetya Bambang Prasetya Bambang Prasetya Bambang Prasetya Bustomi - Bustomi Darwis, Abdul Aziz Dede Rais Diana Dewi Diana Dewi, Diana Diana Nurani Djumali Mangunwidjaja Djumali Mangunwidjaja Djumali Mangunwidjaja Dwi - Susilaningsih Dwi Purnomo Dwi Purnomo Dwi Setyaningsih DYAH NOOR HIDAYATI Dyah Noor Hidayati E. Gumbira Sa’id E. Gumbira-Sa’id E. Mardliyati Elisa Julianti Endang Gumbira Said Endang Warsiki Endang Warsiki dan Citra Dewi Wahyono Putri (E-Jurnal Agro-Industri Indonesia) Eni Dwi Islamiati Eni Dwi Islamiati Eni Dwi Islamiati, Eni Dwi Erwahyuni E Prabandani ERWAHYUNI ENDANG PRABANDARI ERWAHYUNI ENDANG PRABANDARI Erwahyuni Prabandari Erwahyuni Prabandari, Erwahyuni Essa Annisa Syadiah Etik Mardliyati Etik Mardliyati Etik Mardliyati, Etik Etty Riani FARAH FAHMA FENTRI PARAMITHA PUTRI Fitriani Kasim Gamma Irca Pradikta Griselda Happy Ramadhani Gumbira-Sa'id, E Gustri Yeni Gustri Yeni Han Roliadi Hanifah FUADI Hanny Hafiar Hendri Muchtar Hendri Muchtar, Hendri Herastuti Sri I Nyoman Jaya Wistara Iftachul Farida Ika Amalia Kartika Ike Sitoresmi M Purbowati Illah Sailah Irawadi Jamaran Irvan Setiadi Kartawiria IS HELIANTI Isroi Isroi Isroi Jayawarsa, A.A. Ketut Joko Santoso Kasid, Sri Kaidah kusnadi, adhi Lanjar Sumarno Lanjar Sumarno Lestari, Puji Liesbetini Haditjaroko Liesbetini Hartoto Lucky Risanto M Irfani ABDULLAH M. ANWAR NUR M. Daud Machfud Mala Nurilmala Manalu, Lamhot Mardliyati, Etik Muhammad Arif Darmawan Muhammad Daud Muhammad Rasyid RAMADHAN Muhammad Tasrif Muhammad Tasrif Mulyorini Rahayuningsih Murdiyatmo, Untung Muslich Muslich, Muslich N. A. Evalia Nabilah, Siti Nadia STEPANI Nastiti Siswi Indrasti Nasution, Nurul Cinthiya nFN Misgiyarta NIKNIK NURHAYATI Ninik Purbosari Nur Atifah Nur Richana Nurika Asih SETIYANI Nusaibah - Nusaibah Prayoga SURYADARMA Ridwansyah Ridwansyah Rini Purnawati Rofiq Sunaryanto Rofiq Sunaryanto S Heris Anita, S Heris S Joni Munarso Sa’id, E. Gumbira Sapta Raharja Sarifah Nurjanah Selvia Mahilda RIDHOHA Shinta PERMATASARI Siti Nabilah Sony Hartono Wijaya Sudirman Sudirman Suharyanto Suprihatin Suprihatin Surono SURONO Tajuddin Bantacut Taufik Hidayat Titi Candra Sunarti Tri Panji Tun T. Irawadi Tun Tedja Irawadi Tun Tedja Irawadi Wahono Sumaryono Wasrin Safii Wasrin Syafii Widya Fatriasari Widya FATRIASARI Yandra Arkeman Yandra Arkeman Yandra Arkenan Yeni, Gustri Yeni, Gustri