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Studi Adverse Drug Reactions Penggunaan Obat Antiepilepsi Monoterapi Pada Anak di Rumah Sakit - Studi Farmakovigilans Putri Ramdaniah; Dwi Monika Ningrum; Depi Yuliana; Dedent Eka Bimmahariyanto S.; Recta Olivia Umboro
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 3, No 2 (2022): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v3i2.8384

Abstract

ABSTRAKPengobatan epilepsi membutuhkan waktu yang lama, penghentian terapi dilakukan secara bertahap apabila dicapai bebas kejang selama dua tahun. Pengobatan yang bersifat jangka panjang dikaitkan dengan peningkatan efek samping dan membutuhkan monitoring pengobatan. Pasien anak sering mengalami efek samping obat yang sama dengan pasien dewasa, namun reaksi obat yang tidak dikehendaki pada pasien anak lebih sulit karena perbedaan karakteristik antara pasien anak dan pasien dewasa juga mempengaruhi efikasi dan efek samping obat. Tujuan penelitian ini untuk menghitung angka kejadian ADRs dan Klasifikasi Jenis ADRs pada penggunaan obat antiepilepsi Monoterapi. Metode yang digunakan yaitu penelitian cross sectional dengan pengambilan data secara prospektif, penilaian kausalitas ADRs menggunakan algoritma naranjo, selama periode penelitian didapatkan 56 pasien yang mendapatkan terapi monoterapi dari total 86 pasien. jenis-jenis ADRs yang terjadi pada pasien yaitu gangguan gastrointestinal 32,35%, reaksi kulit gatal dan kemerahan terjadi 7,35%, gangguan metabolik sebanyak 10,29%, dan gangguan CNS (Central nervous system) sebanyak 10,29%. Kata kunci : Adverse drug reactions; Antiepilepsi; Anak-anak.ABSTRACTEpilepsy treatment takes a long time, discontinuation of therapy is carried out gradually if achieved without seizures for two years. Treatment is long-term treatment with increased side effects and requires medication monitoring. Pediatric patients often experience the same side effects of drugs as adults, but adverse drug reactions in pediatric patients are more difficult because differences in characteristics between patients and adult patients also affect the efficacy and side effects of drugs. The purpose of this study was to calculate the incidence of ADR and Classification of Types of ADR in the use of monotherapy antiepileptic drugs. The method used is a cross sectional study with prospective data collection, ADR Causality Assessment using the Naranjo Algorithm, during the study period 56 patients received monotherapy therapy from a total of 86 patients. The types of ADR that occur in patients are gastrointestinal disorders 32.35%, itching and skin reactions that occur 7.35%, metabolic disorders as much as 10.29%, and CNS (Central Nervous System) disorders as much as 10.29%.Keywords : Adverse drug reactions; Antiepileptic; Pediatric.
EDUKASI SISTEM REPRODUKSI SEBAGAI UPAYA PENCEGAHAN PENYAKIT INFEKSI MENULAR SEKSUAL PADA REMAJA Fitri Apriliany; Elis Cholisah; Recta Olivia Umboro; Dedent Eka Bimaharyanto
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 6, No 4 (2022): Desember
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v6i4.11435

Abstract

ABSTRAKMenurut Centers for Disease Control (CDC) tahun 2021 penyakit menular seksual yang paling banyak dilaporkan dari berbagai negara adalah sifilis, gonore, klamidia, chancroid, dan HIV. Berdasarkan data pemerintahan Provinsi Kalimantan Selatan pada tahun 2017 menunjukkan bahwa terdapat 3 Kota/Kabupaten yang memiliki kasus infeksi menular seksual tertinggi di Kalimantan Selatan yaitu Kota Banjarmasin (3.507 kasus), Kabupaten Hulu Sungai Utara (3.134 kasus), Kabupaten Banjar (1.715 kasus) dan data dari kemenkes RI menunjukkan persentase tertinggi terdapat pada kelompok usia 25-49 tahun (71,3%), usia 20-24 tahun (16,3%). Tujuan pengabdian ini adalah meningkatkan pemahaman terhadap sistem reproduksi sebagai upaya pencegahan penyakit infeksi menular pada remaja dan membantu program pemerintah mencapai eliminasi HIV-AIDS dan penyakit infeksi menular seksual (PIMS) pada tahun 2030. Metode pengabdian adalah sosialisasi sistem reproduksi dan PIMS serta dialog interaktif/tanya jawab. Evaluasi dilakukan dengan diskusi tanya jawab, pretest dan posttest dengan peserta. Hasil kegiatan ini menunjukkan bahwa terdapat peningkatan pengetahuan mahasiswa/i dengan hasil rata-rata pretest (38,5) dan posttest (85,7). Kesimpulan kegiatan ini adalah terjadi peningkatan pengetahuan rata-rata sebesar 47,2. Kata kunci: edukasi; sistem reproduksi; PIMS. ABSTRACTAccording to Centers for Disease Control (CDC) in 2021, the most reported sexually transmitted diseases from various countries are syphilis, gonorrhea, chlamydia, chancroid, and HIV. Based on data from South Kalimantan Provincial government in 2017 shows that there are 3 cities/districts that have the highest cases of sexually transmitted infections (STIs) in South Kalimantan, namely the city of Banjarmasin (3,507 cases), Kab. Hulu Sungai Utara (3,134 cases), Banjar Regency (1,715 cases) and data from kemenkes RI show that the highest percentage is in 25-49 year age group (71.3%), 20-24 years old (16.3%). This activity aimed to determine to increase understanding of reproductive system as an effort to prevent infectious diseases in adolescents and help government programs achieve elimination of HIV-AIDS and STIs by 2030. The program was carried out by following methods: the dissemination of reproductive system and STIs and interactive dialogue/ question and answer. Evaluation is done through question and answers discussion, pretest and posttest with participants. The results of this activity indicate that there is an increase in students knowledge with average results of pretest (38,5) and posttest (85,7). The conclusion is an increase in students knowledge with average increase 47.2. Keywords: education; reproduction system; STIs.
PENINGKATAN KESADARAN MENJAGA KESEHATAN DIRI DAN LINGKUNGAN PADA ANAK USIA SEKOLAH Recta Olivia Umboro; Atri Sri Ulandari; Putri Ramdaniah
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 6, No 4 (2022): Desember
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v6i4.11488

Abstract

ABSTRAKProfil kesehatan Provinsi NTB pada tahun 2021 menunjukkan bahwa nilai Angka Harapan Hidup (AHH) Kabupaten Lombok Tengah masih di bawah nilai Provinsi NTB sebesar 0.31. Lombok Tengah merupakan kabupaten yang berada di Provinsi Nusa Tenggara Barat (NTB), dimana jumlah penduduk terbanyak berada pada kategori usia sekolah (6-12 tahun). Anak usia sekolah rentan sekali mengalami gangguan kesehatan. Rendahnya AHH menjadi indikator bahwa derajat kesehatan di Kabupaten Lombok Tengah perlu ditingkatkan melalui kegiatan berupa edukasi Perilaku Hidup Bersih dan Sehat (PHBS). Tujuan dari pelaksanaan kegiatan edukasi PHBS adalah untuk meningkatkan pemahaman dan kepedulian terkait PHBS kepada anak usia sekolah. Sasaran dalam kegiatan ini yaitu peserta didik di SD Negeri 2 Batukliang, Lombok Tengah. Metode yang digunakan dalam kegiatan edukasi berupa penyuluhan melalui media gambar dan video, praktek, dialog interaktif seputar PHBS dan permainan. Hasil evaluasi kegiatan ( pretest dan posttest ) menunjukkan kenaikan nilai rerata posttest sebesar 59.08%, Kegiatan edukasi ini berhasil meningkatkan pengetahuan dan pemahaman peserta terkait PHBS. Kata kunci: edukasi; Kesehatan; PHBS; anak usia sekolah ABSTRACT\The health profile of the Province of NTB in 2021 shows that the value of life expectancy (VOLE) in Central Lombok district is below than Province of NTB, which is 0.31. Central Lombok is a district in the Province of West Nusa Tenggara (NTB), with the largest population in the school age range (6-12 years old). The category of school-age children is very vulnerable to getting health problems. The low of VOLE is an indicator that the health status in Central Lombok district needs to be improved through hygienic and healthy behavior education (PHBS). The aim of this activity is to increase knowledge,  awareness about the importance of PHBS for school-age children. The targets in PHBS education are students at State Elementary School 02 Batukliang, Central Lombok. The methods used in this activity are counseling using image and video media, PHBS practice, interactive dialogue and games. The results of the activity evaluation (pretest and posttest) showed an increase in the average posttest score of 59.08%. This educational activity succeeded in increasing the participants knowledge and understanding of PHBS. Keywords: education; health; PHBS; school-age children
KONSELING, INFORMASI, DAN EDUKASI KESEHATAN REPRODUKSI PADA REMAJA Regina Pricilia Yunika; Recta Olivia Umboro; Fitri Apriliany; M. Zulfikar Al Fariqi
Jurnal LENTERA Vol. 2 No. 2 (2022): Jurnal LENTERA
Publisher : Stikes Yarsi Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (551.512 KB) | DOI: 10.57267/lentera.v2i2.195

Abstract

Adolescence is a period of transition, and tends to want to try new things so that it can have a negative impact on adolescents. Lack of knowledge related to reproductive health can cause reproductive health problems for adolescents. It is believed that improving the degree of reproductive health to change behavior in order to live a healthy life can be done by providing reproductive health education. Understanding and information on reproductive health is very much needed at this phase and education can be done through the provision of counseling or which includes material about the changes that occur when entering adolescence. The purpose of this activity is to educate young people regarding reproductive health issues. The method of implementing this community service activity was carried out on productive age teenagers at SMA Negeri 2 Mataram, due to limited space and the obligation to apply health protocols. The participants of this activity were represented by 25 students who were selected based on membership in theYouth Red Cross (PMR) extracurricular and the School Health Unit. (UKS). This activity is carried out with the mechanism of counseling, information, education, through health promotion media in the form of leaflets and counseling. Accurate information related to adolescent's concern for their reproductive health. The majority of SMA Negeri 2 Mataram students still think that reproductive health is something they do not fully understand. For this reason, they need to be given information to better understand reproductive health. In conclusion, providing education to adolescents about reproductive health can increase the knowledge and understanding of adolescents about the reproductive system. The PKM team evaluates what has been conveyed by asking the youth to mention a healthy reproductive system. This activity provides benefits for students of SMA Negeri 2 Mataram who previously did not know about good reproductive health to better understand their reproductive health.
UJI INVIVO AKTIVITAS DIURETIKA EKSTRAK ETANOL 70% DAUN UNGU (Graptophyllum pictum (L) Griff) PADA MENCIT PUTIH JANTAN GALUR WISTAR Recta Olivia Umboro; Dedent Eka Bimmaharyanto; Fitri Apriliany; Iva Rinia Dewi
Jurnal Insan Farmasi Indonesia Vol 5 No 2 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i2.1137

Abstract

Traditionally, daun ungu plant (Graptophyllum pictum (L) Griff) has been known to have pharmacological effects that can help with a variety of health issues. This plant’s flavonoid compounds content is thought to have diuretic activity in this plant is believed to have activity. The purpose of this study is to determine the diuretic activity and optimal dose of etanol extract of 70% daun ungu administered orally to male white mice. This is an experimental study with a completely randomized design (CRD) that includes 1 negative control group (Na.CMC 0.5%), 1 positive control group (furosemide 40 mg) and 3 test groups of 70% daun ungu ethanol extract doses of 10 mg/kg BW, 25 mg/kg BW and 40 mg/kg BW with urine volume test parameters. One-way ANOVA and Kruskal-Wallis statistical test were used to analyze the data. The results showed that one-way ANOVA revealed a P < 0.05 (0.012), and P ≤ 0.05 (0.051) for the Kruskal-Wallis test. It can be concluded that 70% daun ungu etahanol exctract has effective diuretics, with an optimal dose
EDUKASI DAN PRAKTEK CUCI TANGAN PAKAI SABUN UNTUK KESEHATAN DAN PENCEGAHAN DIARE PADA ANAK Fitri Apriliany; Recta Olivia Umboro; Fatimatuzzahra Fatimatuzzahra; Hilda Hastuti
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 7, No 2 (2023): June
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v7i2.14708

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ABSTRAKBeberapa permasalahan kesehatan di Provinsi Nusa Tenggara Barat (NTB) yaitu diare, malaria, TBC, dan kondisi lingkungan yang tercemar oleh tinja manusia seperti diare serta sanitasi yang rendah terutama pada anak-anak. Berdasarkan data Dinas Kesehatan Kota Mataram pada Januari 2023 terdapat 471 kasus diare khususnya pada anak-anak dan balita. Mitra pengabdian ini adalah MI NW Karang Bata Mataram dan merupakan salah satu sekolah di Kota Mataram yang memiliki jumlah siswa/i yang banyak dan masih kurang mengetahui 6 langkah cuci tangan pakai sabun. Tujuan kegiatan ini yaitu memberikan pemahaman dan manfaat mengenai pentingnya cuci tangan pakai sabun untuk kesehatan. Metode pengabdian adalah sosialisasi (pemberian materi edukasi, diskusi tanya jawab, pretest dan posttest). Evaluasi dilakukan dengan pretest, posttest,dan diskusi tanya jawab. Hasil kegiatan ini diikuti oleh 48 peserta pada 25 Februari 2023 dan menunjukkan peningkatan pengetahuan siswa/i dengan rata-rata pretest (40,5) dan posttest (89,0). Kesimpulan pengabdian ini adalah rata-rata peningkatan pengetahuan siswa sebesar 48,5 dengan persentase peningkatan hardskill sebesar 48,5%. Dari kegiatan ini, siswa/i dapat mengimplementasikan perilaku hidup bersih dan sehat dan keterampilan mencuci tangan dengan langkah cuci tangan yang sesuai dengan standar 6 langkah cuci tangan. Kata kunci: cuci tangan; diare; edukasi ABSTRACTSeveral health problems in West Nusa Tenggara (NTB) Province, namely diarrhea, malaria, tuberculosis, and environmental conditions polluted by human feces such as diarrhea and poor sanitation, especially in children. Based on data from Mataram City Health Office in January 2023 there were 471 cases diarrhea, especially in children and toddlers. This partner is MI NW Karang Bata Mataram and is one of schools in Mataram City which has large number students who still don't know the 6 steps washing hands with soap. The purpose this activity is provide understanding and benefits regarding importance washing hands with soap for health. The method is socialization (providing educational materials, question and answer discussions, pretest and posttest). Evaluation is done by pretest, posttest, and question and answer discussion. Results were attended by 48 participants on February 25, 2023 and showed an increase in students' knowledge with average pretest (40.5) and posttest (89.0). This concludes that average increase in student knowledge is 48.5 with percentage increase in hard skills 48.5%. Therefore, new insight and better understanding were gained to live healthily behavior and implement their hand-washing skills with hand washing steps that are following the 6 standard hand-washing steps. Keywords: hand washing; diarrhea; education
UPAYA PENINGKATAN EKSISTENSI PERAN FARMASIS MELALUI EDUKASI APOCIL KENAL DAGUSIBU Recta Olivia Umboro; Fitri Apriliany; Anita Mursiany; Dedent Eka Bimmaharyanto Sarsono; Dwi Monika Ningrum
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 7, No 3 (2023): September
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v7i3.19833

Abstract

ABSTRAKFarmasis atau yang lebih dikenal dengan nama apoteker merupakan salah satu profesi yang memiliki peran yang cukup signifikan dalam dunia kesehatan khususnya dibidang obat. Walau telah diakui secara undang-undang oleh negara,  namun masih banyak dari masyarakat Indonesia yang belum mengenal peran dan fungsi dari apoteker. Kegiatan edukasi dengan tema APOCIL kenal DAGUSIBU yang berlokasi di Madrasah Ibtidaiyah (MI) NW Karang Bata Mataram bertujuan untuk untuk memperkenalkan profesi apoteker sekaligus untuk menciptakan agen perubahan sadar obat sedini mungkin di masyarakat. Peserta edukasi merupakan siswa usia sekolah (6-12 tahun). Metode edukasi dilakukan menggunakan media pembelajaran audio-visual (power point, video animasi Acil-DAGUSIBU) dan Game Base Learning. Evaluasi dilakukan melalui kegiatan pretest dan posttest. Pelaksanaan kegiatan dihadiri oleh 40 orang peserta sekolah dasar kelas 3,4,5. Hasil kegiatan berupa terpilihnya duta apocil dan diperoleh nilai rata-rata evaluasi kegiatan pretest yang sebesar 40.00 dan nilai rata-rata posttest sebesar 90.00.  Sehingga dapat disimpulkan bahwa kegiatan edukasi ini berdampak pada perubahan sikap  pemahaman dan pengetahuan dari peserta, hal ini ditunjukkan dengan adanya peningkatan nilai evaluasi sesudah diberikan perlakuan sebesar 125%. Kata kunci: edukasi; APOCIL; DAGUSIBU. ABSTRACTThe profession of pharmacists, or just pharmacists, is important to the health sector, particularly in the area of medicine. Many Indonesians are still unaware of the role and function of pharmacists, despite the fact that the state has officially recognised them. The goal of the educational programme with the title "APOCIL knows DAGUSIBU," which is held at Madrasah Ibtidaiyah (MI) NW Karang Bata Mataram, is to raise awareness of drugs early in society and promote the profession of pharmacy. Participants in education are students in school (6–12 years old). Game Base Learning and audio-visual learning resources (Power Points, Acil-DAGUSIBU animated movies) are used in the instructional approach. Activities for the pretest and posttest are used for evaluation. Forty primary school students in grades three, four, and five participated in the exercise. The activity resulted in the selection of Apocil ambassadors; the average score on the pretest activity evaluation was 40.00, and the average score on the posttest was 90.00. Therefore, it can be said that this educational exercise has an effect on how the participants perceive and feel about themselves, as seen by the evaluation ratings rising by 125% following treatment. Keywords: education; APOCIL; DAGUSIBU.
Evaluation Conformity Rejimen Peptic Ulcer Drug Therapy In Inpatient Care Facility At West Nusa Tenggara Regional Public Hospital Recta Olivia Umboro; Fitri Apriliany; Vera Fitriya Ersalena
Parapemikir : Jurnal Ilmiah Farmasi Vol 11, No 1 (2022): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v11i1.2481

Abstract

Peptic ulcers are lesions in the stomach or duodenum caused by an imbalance between aggressive and mucosal protective factors. External factors such as smoking, coffee consumption, and helycobacter pylori infection are triggers for peptic ulcers. In 2017, there is an increase in the prevalence of gastritis (dyspepsia, peptic ulcer) in West Nusa Tenggara. The aim of this research to determine the description and appropriateness of drug therapy in patients with peptic ulcers. The observational method was used in this research with a descriptive cross-sectional study design. Data were collected retrospectively through tracing treatment  on the medical records of peptic ulcer patients at the in-patient facility of the West Nusa Tenggara Regional Public Hospital for the period January 2018 - January 2020. Based on inclusion and exclusion criteria, the number of prescriptions is 114 from 18 patients. The patient characteristic based on age was obtained between 55 – 64 years with a percentage of 50% with 55,56% suffered by men. The largest percentage of therapy was between PPI + Antacids + Sucraflat (38,89%). The percentage of the PPI group were omeprazole (88.89%) and lansoprazole (22.22%). In H2RA group, ranitidine (16.67%). Sucraflat (83.33%), ondansetron (33.33%) and antacids (55.56%). The percentage of the suitability of drug therapy is 88%. The percentage of dosage therapy appropriate is 100%. 
Penerapan Media Gambar Dalam Kegiatan Ekstrakurikuler Bahasa Inggris Siswa Madrasah Ibtidaiyah Hastuti, Hilda; Fatimatuzzahra; Agus Syahid; Fitri Apriliany; Recta Olivia Umboro
Jurnal Ilmiah Pengabdian dan Inovasi Vol. 2 No. 2 (2023): Jurnal Ilmiah Pengabdian dan Inovasi (Desember)
Publisher : Insan Kreasi Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57248/jilpi.v2i2.341

Abstract

The development of information technology requires teachers to be able to present more interesting English language learning. Picture is a learning medium that can be used as a strategy in learning English at MI NW Karang Bata Mataram. The methods used are (1) Problem identification, at this stage observations are made at the school and analysis of student needs to determine the initial needs of MI NW Karang Bata students regarding materials, media and methods used; (2) the solution offered is picture and game based learning methods. The 'Read for Me' game is an appropriate method to use to make students more interested in learning English; (3) Picture is very helpful for teachers and students in the learning process, because elementary students level need concrete media to be able to understand the information or concepts provided. The aim of this devotion is to create learning that can build students' motivation and interest in learning. The results of the implementation of this service show that the application of image media using the 'Read For Me' game method can create more interesting English learning so as to increase students' motivation and interest in learning English
Sensitivity of Bacteria causing Hospital-Acquired Pneumonia (HAP) in the Intensive Care Unit (ICU) to Empiric Antibiotics APRILIANY, FITRI; Umboro, Recta Olivia; Ersalena, Vera Fitriya; Setiawan, Deni; Cholisah, Elis
BORNEO JOURNAL OF PHARMASCIENTECH Vol 9 No 1 (2025): Borneo Journal Of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59053/bjp.v9i1.565

Abstract

The main therapy for the treatment of pneumonia is antibiotics. The use of antibiotics requires special attention to prevent antibiotic resistance. Therefore, it is important to know the pathogenic microorganisms that cause hospital-acquired pneumonia (HAP) infections. This study aimed to describe the sensitivity of negative-positive bacteria to empiric antibiotics in HAP patients. The study method was an analytical descriptive observational study with a cross-sectional design. Data were collected from patient medical records for the period January 2019 – December 2020. Inclusion criteria were ICU patients diagnosed with HAP, aged 15 years, with complete medical records (age, sputum culture, leukocytes, chest x-ray results), treatment history and outcome parameters (vital signs). Exclusion criteria were pregnant patients, involuntary discharge, and ICU stay of less than 48 hours. The data in this study were analyzed descriptively and Likelihood Ratio. The results of the description showed that the empiric antibiotics with sensitivity more than 70% against gram-positive bacteria causing HAP were rifampin (78%), TMP-sulfamethoxazole (78%), vancomycin (100%), and linezolid (100%) while the empiric antibiotics with sensitivity more than 70% against gram-negative bacteria was cefoperazone-sulbactam (≥75%), followed amikacin and imipenem (≥55%). Meanwhile, the empiric antibiotics had a very low sensitivity (≤ 50%) against ESLB-producing bacteria and MRSA. There is a significant relationship between age and educational level factors and bacterial growth in sputum cultures (p<0.05). Conclusion: Vancomycin and linezolid are sensitive to gram-positive bacteria, cefoperazone-sulbactam is sensitive to gram-negative bacteria and resistance to ESLB-producing bacteria and MRSA has occurred.