Article Per Year (5 Year)
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All Journal International Journal of Public Health Science (IJPHS) Archive of Community Health Medicina Sport and Fitness Journal E-Journal of Tourism E-Jurnal Medika Udayana Ecotrophic, Journal of Environmental Science Media Kesehatan Masyarakat Indonesia Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Berkala Epidemiologi Indonesian Journal of Tropical and Infectious Disease Jurnal Penelitian Pendidikan IPA (JPPIPA) ISM (Intisari Sains Medis) : Jurnal Kedokteran Jurnal Pendidikan Kesehatan Rekreasi Bioscientia Medicina : Journal of Biomedicine and Translational Research JURNAL ILKES (Jurnal Ilmu Kesehatan) Bioscientia Medicina : Journal of Biomedicine and Translational Research Bali Dental Journal Lux Mensana: Journal of Scientific Health Public Health and Preventive Medicine Archive Jurnal Ilmu Kesehatan Masyarakat Seminar Ilmiah Nasional Teknologi, Sains, dan Sosial Humaniora (SINTESA) Physical Therapy Journal of Indonesia
I Made Ady Wirawan
Departemen Kesehatan Masyarakat Dan Kedokteran Pencegahan, Fakultas Kedokteran Universitas Udayana
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences

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The Hidden Hazard of Celebration: A Meta-Analysis of Ocular Morbidity from Colored Powder Festivals and Implications for Global Travel Medicine Frangklin Refelino Jotlely; I Made Ady Wirawan; I Gusti Ayu Made Juliari; Ida Ayu Ary Pramita
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 10 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i10.1417

Abstract

Background: The globalization of colored powder festivals, such as Holi, has exposed millions, including international tourists, to significant ocular health risks from synthetic industrial dyes that have replaced traditional organic powders. This study was conducted to quantify the prevalence of acute ocular morbidities from these festivals, providing an evidence base to inform clinical practice and public health policy, particularly within travel medicine. Methods: Following PRISMA guidelines, a systematic search was conducted in PubMed, Google Scholar, ScienceDirect, and ProQuest for observational studies published up to July 2024. Studies reporting ocular complications from colored powder exposure were included. Data were extracted by two independent reviewers, and methodological quality was assessed using JBI checklists. A random-effects model was used to calculate pooled prevalence for key ocular injuries. Heterogeneity was investigated using sensitivity analyses, and publication bias was assessed with funnel plots. Results: Six studies from India, encompassing 189 patients, met the inclusion criteria for quantitative analysis. The patient population was predominantly young males (mean age 20-30 years). The meta-analysis revealed a high pooled prevalence of key ocular morbidities. The prevalence for chemical conjunctivitis was 95% (95% CI: 87%-100%), though with substantial but anticipated heterogeneity (I²=82%). The prevalence for corneal epithelial defects was 37% (95% CI: 23%-53%; I²=45%), and for superficial punctate keratopathy was 75% (95% CI: 57%-90%; I²=0%). Most injuries were bilateral. Conclusion: Participation in colored powder festivals, based on extensive evidence from Holi in India, presents a quantifiable and significant risk of acute ocular morbidity. The high prevalence of chemical-induced ocular surface disease necessitates urgent recognition of this "hidden hazard." Proactive, evidence-based preventive strategies, including tiered recommendations for protective eyewear and updated pre-travel health advisories, are imperative to safeguard the vision of millions of celebrants worldwide.
Lower Body Negative Pressure for Spaceflight Associated Neuro-ocular Syndrome: A Systematic Review and Meta-Analysis Fabiola Supit; I Made Ady Wirawan; I Gusti Ayu Made Juliari; Ida Ayu Ary Pramita
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 12 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i12.1454

Abstract

Background: Spaceflight associated neuro-ocular syndrome (SANS) is a critical health risk for astronauts on long-duration missions, characterized by potentially vision-altering ocular changes. Lower body negative pressure (LBNP) is a primary countermeasure designed to reverse the foundational cephalad fluid shifts. This study provides the first rigorous, quantitative synthesis of LBNP's efficacy on key SANS-related ocular parameters. Methods: Following PRISMA guidelines, a systematic search of PubMed, ScienceDirect, and the Cochrane Library (2015–2025) was conducted. Studies quantifying the effect of LBNP on intraocular pressure (IOP), optic nerve sheath diameter (ONSD), or choroidal thickness (CT) in microgravity or its ground-based analogs were included. A random-effects meta-analysis calculated the pooled mean difference (MD). Leave-one-out sensitivity analysis and assessment of publication bias were performed to ensure robustness. Results: Seven studies (N=89 subjects) met the criteria. The meta-analysis demonstrated that LBNP application resulted in statistically significant reductions in IOP (MD = -2.15 mmHg; 95% CI [-3.01, -1.29]; p < 0.001), ONSD (MD = -0.31 mm; 95% CI [-0.45, -0.17]; p < 0.001), and subfoveal Choroidal Thickness (MD = -18.50 µm; 95% CI [-25.65, -11.35]; p < 0.001). Subgroup analysis revealed a more pronounced effect in ground-based studies. The results were robust in sensitivity analyses, and funnel plots suggested a low risk of publication bias. Conclusion: This meta-analysis provides robust, quantitative evidence supporting LBNP's efficacy in acutely mitigating the cardinal structural signs of SANS. By directly counteracting the underlying pathophysiology, LBNP is affirmed as a cornerstone countermeasure technology essential for preserving astronaut ocular health during the upcoming era of deep space exploration.
Therapeutic Keratoplasty for Severe, Travel-Associated Fungal Keratitis: A Meta-Analysis of Globe Salvage and Visual Acuity Outcomes Putu Rima Adilitha Widyasari; I Made Ady Wirawan; I Gusti Ayu Made Juliari; Ida Ayu Ary Pramita
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 12 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i12.1457

Abstract

Background: Severe, travel-associated fungal keratitis represents a formidable diagnostic and therapeutic challenge, often progressing to corneal perforation despite aggressive medical therapy. Therapeutic keratoplasty (TK) is frequently required to preserve globe integrity. However, its efficacy in this specific, epidemiologically distinct cohort of patients remains poorly quantified. This meta-analysis aimed to synthesize the available evidence on globe salvage and visual acuity outcomes following TK for severe fungal keratitis acquired during international travel. Methods: A systematic search was conducted in PubMed, Scopus, and Web of Science for studies published between January 2015 and December 2024, reporting outcomes of TK for travel-associated fungal keratitis. The primary outcome was the proportion of cases achieving globe salvage, defined as the avoidance of enucleation or evisceration. The secondary outcome was the mean improvement in Best-Corrected Visual Acuity (BCVA) measured in LogMAR units. Data were pooled using a random-effects model. Heterogeneity was assessed using the I² statistic. Results: Seven retrospective case series met the inclusion criteria, comprising a total of 102 eyes. The included studies were geographically diverse, with patient travel histories predominantly linked to tropical and subtropical regions in Southeast Asia and South America. The pooled proportion for globe salvage was 89.2% (95% Confidence Interval [CI]: 82.5% to 94.1%). There was low to moderate heterogeneity among the studies for this outcome (I² = 31%, p=0.19). The pooled mean improvement in BCVA from pre-operative assessment to final follow-up was 1.21 LogMAR (95% CI: 0.98 to 1.44). Substantial heterogeneity was observed for the visual acuity outcome (I² = 78%, p<0.001). The most commonly identified fungal genera were Fusarium and Aspergillus. Conclusion: Therapeutic keratoplasty demonstrates a high rate of anatomical success, effectively salvaging the globe in the vast majority of patients with severe, travel-associated fungal keratitis. While visual acuity is significantly improved, the final outcomes remain guarded and are highly variable. These findings underscore the critical role of TK in the management of this sight-threatening condition and highlight the need for strategies to improve post-operative visual prognosis.
Antenatal Education to Support Triple Elimination Program: A Systematic Literature Review Sulyastini, Ni Komang; Wirawan, I Made Ady
Jurnal Penelitian Pendidikan IPA Vol 9 No 8 (2023): August
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i8.4234

Abstract

This study aims to describe cases of transmission of HIV, hepatitis B and syphilis from mother to child and how the role of antenatal education in supporting the triple elimination program. This research was conducted using a systematic literature review approach. Researchers collected data from research articles that have been published in Scopus indexed international electronic journals. Data was collected using several keywords with the Google search engine and portals providing articles from Scopus indexed journals, such as ScienceDirect, MDPI, and NCBI. The data collected was then analyzed by researchers using an interactive data analysis model. The results of the analysis found that the implementation of triple elimination has been successfully carried out in various countries, although there are still various obstacles that must be faced in its implementation. Furthermore, several studies have also found that antenatal education has an important role in reducing the risk of transmission of HIV, hepatitis B and syphilis from mother to child. So, it can be concluded that antenatal education is crucial to provide in order to support the triple elimination program to prevent cases of transmission of HIV, hepatitis B and syphilis from mother to child
Co-Authors Akatsu, Haruko Ariana, Putu Agus Aryanita, Made Ayu Ratih Astawastini, I Dewa Ayu Mas Manik Bagus Komang Satriyasa Carolyna Mairing Cokorda Agung Wahyu Purnamasidhi Cokorda Bagus Jaya Lesmana Cokorda Bagus Jaya Lesmana, Cokorda Bagus Jaya Desak Nyoman Widyanthini Desak Putu Yulita Kurniati Deswandri Deswandri Dewa Nyoman Wirawan Dewa Nyoman Wirawan, Dewa Nyoman Dinar Lubis Dyah Pradnyaparmita Duarsa Egiya Goldarosa Sinuraya Erawati, Ni Kadek Erna Ervan Suryanti Umbu Lapu Fabiola Supit Florensia, Maria Frangklin Refelino Jotlely Futi Nurul Destya Ganesa Puput Dinda Kurniawan Gede Parta Kinandana Gunawan, I Made Abdi HARI MULYAWAN I Dewa Ayu Inten Dwi Primayanti I Gusti Agung Dyah Ambarawati I Gusti Ayu Made Julari I Gusti Ayu Made Juliari I Kadek Pendi Aprinta I Ketut Indra Wiguna Cakera I Ketut Suyasa I Komang Widarma Atmaja I Made Artana I Made Bakta I Made Jawi I Made Kerta Duana I Made Krisna Dinata I MADE MULIARTA . I Made Niko Winaya I Made Pande Dwipayana I Made Sukawinaca I Nyoman Mangku Karmaya I Wayan Putu Sutirta Yasa I Wayan Weta Ida Ayu Ary Pramita Ida Bagus Subanada Ida Bagus Yorky Brahmantya IKW. Suryawan Indra Wiguna Cakera, I Ketut IP. Adiartha Griadi Isabella Soerjanto Putri Istiana Marfianti J. A. Pangkahila Josua Aditya Manuel Kadek Dena Ayu Ersafira Kadek Tresna Adhi Karya, I Kadek Jony Dwi Ketut Ariawati Ketut Suarjana Komang Ayu Kartika Sari Lesmana, Cokorda Agung Bagus Jaya LMIS. Handari Adiputra Louise Cinthia Hutomo Luh Pitriyanti Luh Pitriyanti Luh Yulia Adiningsih Luh Yulia Adiningsih Made Agus Hendrayana MADE RATNA SARASWATI . Malcolm Abernethy Marfianti, Istiana Mia Ayustina Prasetya Nadila Sari, Putri Ngurah Agus Sanjaya ER Ni Kadek Dian Candra Dewi Ni Kadek Erna Erawati Ni Kadek Sutini Ni Ketut Sri Lestari Ni Luh Made Susanthi Pramandani Ni Luh Putu Mira Anggriani Ni Luh Putu Nurhaeni Ni Made Dian Kurniasari Ni Made Sri Nopiyani Ni Made Suasti Wulanyani Ni Nyoman Sri Budayanti Ni Putu Ita Mahayati Ni Wayan Mega Sri Wahyuni Ni Wayan Septarini Nijyoti, Nitya Nitya Nijyoti Nurhaeni, Ni Luh Putu Pande Putu Januraga Paramita, Ni Putu Pradnya Peter Larsen Prihandhani, I Gusti Agung Ayu Sherlyna Purnamawati, Susy Putu Astawa Putu Ayu Indrayathi Putu Ayu Sani Utami Putu Eka Arimbawa Putu Ika Anggaraeni Putu Imas Audina Putu Intan Tillama Putu Lestari Sudirman Putu Ratna Kusumadewi Giri Putu Rima Adilitha Widyasari Putu Wulan Putri Amerta R. A.T. Kuswardhani Rania Ayu Permata Putri Kornia Rodney Wu Rosita, Ni Putu Indah Santosa, I Gusti Ngurah Putra Eka Sarah Aldington Saraswati, Ni Luh Putu Gita Karunia Sari, Komang Ayu Kartika Sawitri, Anak Agung Sagung Sugijanto - Sukawinaca, I Made Sulawa, I Ketut Sulyastini, Ni Komang Susy Purnawati Tiara Alexander Wahyuddin, Wahyuddin Wahyudin - Wahyuni, Ni Wayan Mega Sri Wayan Citra Wulan Sucipta Putri Widowati, I Gusti Ayu Rai - Yenny Kandarini Yuntari, Gusti Ayu Krisma