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All Journal Jurnal Ilmiah Farmasi Pharmacon Pharmascience Jurnal Surya Medika Majalah Farmaseutik JMM (Jurnal Masyarakat Mandiri) Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ J-Dinamika: Jurnal Pengabdian Kepada Masyarakat Bubungan Tinggi: Jurnal Pengabdian Masyarakat Journal SAGO Gizi dan Kesehatan Jurnal Insan Farmasi Indonesia Jurnal Farmasi dan Sains Indonesia (JFSI) Journal of Experimental and Clinical Pharmacy (JECP) Journal of Multidisciplinary Applied Natural Science Sasambo Journal of Pharmacy Bulletin of Community Engagement Pengabdian Kampus: Jurnal Informasi Kegiatan Pengabdian Pada Masyarakat Al-Khidmah Jurnal Pengabdian Masyarakat INOVASIA Sinteza Carmin: Journal of Community Service Faedah: Jurnal Hasil Kegiatan Pengabdian Masyarakat Indonesia Aspirasi : Publikasi Hasil Pengabdian dan Kegiatan Masyarakat Jurnal Ilmiah Farmasi Simplisia Jurnal Info Kesehatan
Citrariana, Shesanthi
Universitas Palangka Raya
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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The Effect of Simplisia Drying Method on Antioxidant Activity of Senggani Fruit Extract (Melastoma Malabathricum L.) by DPPH (2,2-diphenyl-1-picrylhydrazyl) Shesanthi Citrariana; Risqika Yulia Tantri Paramawidhita; Melliani Melliani
JURNAL INFO KESEHATAN Vol 19 No 2 (2021): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Politeknik Kesehatan Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol19.Iss2.539

Abstract

Senggani fruit (Melastoma Malabathricum L.) contains anthocyanin that functioning as an antioxidant. Anthocyanin are tremendously sensitive to thermal processes which trigger phytochemical or photo-oxidation reactions that can open anthocyanin rings. The objective of this study is to identify the effect of the simplicia drying method on the antioxidant activity of Senggani fruit extract. Senggani fruit extract was prepared by obtaining samples of ripe fruit, dry sorting, washing, wet sorting, and drying using two methods; sunlight and oven at 70oC. After the simplicia was dry, it was blended and sifted until smooth. The fine simplicia was macerated with 96% ethanol and evaporated to gain a crude extract. The crude extract was assessed with reagents for phytochemical screening. Furthermore, the crude extract was examined for antioxidant activity by the DPPH method. This study implies that the simplicia and crude extract of Senggani fruit from drying in sunlight and oven possess different organoleptic properties such as color, smell, and taste. In phytochemical testing with reagents, it was discovered that anthocyanin compounds were unveiled in drying utilizing sunlight while employing an oven at 70oC; no anthocyanins were found. The antioxidant testing of Senggani fruit extract revealed that the drying method employing sunlight had an IC50 value of 18.8 g/mL while the oven temperature of 70oC owned an IC50 value of 28.3 g/mL. Based on the study results, it can be identified that the simplicia drying method affects the antioxidant activity of the Senggani fruit extract. The drying method in the sun produces extracts with greater antioxidant activity while drying in an oven at 70oC results in a degradation process of anthocyanin compounds, thereby decreasing the antioxidant activity of the Senggani fruit extract.
Formulation and Evaluation of Physical Properties of Antioxidant Effervescent Granules and Extract of Karamunting Flower (Melastoma malabathricum L.) Shesanthi Citrariana; Yahya Febrianto; Thathit Suprayogi; Emma Ayudia Noriadita
INOVASIA Vol 2 No 2 (2024): April
Publisher : LPPM Institut Studi Islam Sunan Doe

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58330/inovasia.v2i2.359

Abstract

Karamunting (Melastoma malabathricum L.) contains several compounds with pharmacological activities including antioxidant, analgesic, anti-inflammatory, antipyretic and diuretic. Karamunting flowers contain flavonoid compounds, saponins and tannins. Tannin compounds can stabilize free radicals by complementing the electron deficiency of free radicals. To increase the utilization of karamunting flowers, it is formulated in the form of effervescent granules. This study aims to determine the ethanol extract of karamunting flower (Melastoma malabathricum L.) with concentrations of 1%, 2%, and 3% can be formulated in the form of effervescent granules. The physical properties of the granules were tested which included organoleptic test, flow rate test, granule compressibility test, dissolving time test and pH of effervescent granules. The results showed that formula 3 with a concentration ratio of 3% ethanol extract was a formula that met the requirements for the physical properties of the granules, namely with a sweet and sour taste, a characteristic odor of karamunting, and a dark purple-brown color. With an average flow rate of 2.853 g/sec, average compressibility of 21.12%, an average dissolving time of 7.52 seconds and a pH measurement of 5.
Kajian aktivitas antioksidan dan sitotoksik ekstrak etil asetat daun jarak pagar (Jatropha curcas) Rahman, Sudarman; Febrianto, Yahya; Citrariana, Shesanthi; Sulistia, Tiya; Alfanaar, Rokiy; Suprayogi, Thathit; Arsana, Mu’afa Purwa; Fatiqin, Awalul
Sasambo Journal of Pharmacy Vol. 6 No. 1 (2025): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v6i1.409

Abstract

Antioxidants are chemical substances that have the ability to protect body cells from damage caused by excessive oxidation reactions. One of the uses of antioxidants from natural materials is jarak pagar leaves (J. curcas). This study aims to determine the antioxidant and cytotoxic activity against shrimp larvae from ethyl acetate extract of J. curcas leaves. Ethyl acetate extract from J. curcas leaves was extracted using the soxhletation method. Phytochemical testing was carried out using the tube method, antioxidant testing using the DPPH method and cytotoxic using the BSLT method. The results of the research showed that J. curcas contained secondary metabolite compounds in the form of flavonoids and polyphenols, the antioxidant activity test of Ethyl acetate extract from J. curcas leaves and the comparison control (vitamin C) produced an IC50 of 71,79±0.35 ppm and 8.78±0.21 ppm, respectively. The cytotoxic test of the ethyl acetate extract of J. curcas leaves contains active compounds that are toxic to the shrimp larvae with an LC50 of 72.13 ppm (LC50≤1000 ppm). The most effective concentration in free radicals scavenging is 160 ppm. Based on the results obtained, the ethyl acetate extract of J. curcas showed strong antioxidant activity and potential as an anticancer agent.
Penyuluhan Bahaya Narkotika, Psikotropika, dan Zat Adiktif di SMPN 1 Sanaman Mantikei Defilia Anogra Riani; Shesanthi Citrariana; Dea Betriksia
ASPIRASI : Publikasi Hasil Pengabdian dan Kegiatan Masyarakat Vol. 3 No. 4 (2025): Juli : ASPIRASI : Publikasi Hasil Pengabdian dan Kegiatan Masyarakat
Publisher : Asosiasi Periset Bahasa Sastra Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/aspirasi.v3i4.2133

Abstract

The abuse of Narcotics, Psychotropics, and Addictive Substances (NAPZA) poses a serious threat to adolescents, including junior high school students. This community service activity aimed to increase students' knowledge and awareness of the dangers of NAPZA through a counseling program conducted at SMPN 1 Sanaman Mantikei. The method involved interactive material presentations, group discussions, and pretest-posttest evaluations. The results showed a significant improvement in students’ knowledge, from 69% to 92% in “good” category after the counseling. This indicates that health education is an effective preventive strategy against substance abuse among adolescents. The activity received positive responses from both students and school staff. Sustainable education programs and integration of NAPZA-related topics into the school curriculum are necessary to build adolescents’ resilience against negative environmental influences. Consistent and collaborative efforts are key to protecting the younger generation from the dangers of drug abuse.
INITIATING NANOBUBBLE TECHNOLOGY FOR IMPROVING FRESHWATER FISH FARMING QUALITY Rahman, Sudarman; Suprayogi, Thathit; Ngazizah, Febri Nur; Citrariana, Shesanthi; Haq, Muhammad Hasanul; Gerung, Jenny Blessia; Rahman, Ansori; Fatiqin, Awalul; Alfanaar, Rokiy; Febrianto, Yahya; Arsana, Mu'afa Purwa
JMM (Jurnal Masyarakat Mandiri) Vol 8, No 5 (2024): Oktober
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v8i5.25685

Abstract

Abstrak: Komunitas KKSS Palangka Raya menghadapi tantangan dalam budidaya ikan air tawar, termasuk kualitas air yang buruk dan pertumbuhan ikan yang tidak optimal, yang menghambat produktivitas perikanan. Program pengabdian ini bertujuan untuk meningkatkan keterampilan 18 anggota komunitas dalam menerapkan teknologi nano bubble sebagai solusi inovatif. Metode yang digunakan meliputi sosialisasi, penyuluhan, diskusi kelompok terarah (FGD), dan praktik langsung penerapan teknologi di kolam ikan mitra. Evaluasi dilakukan dengan wawancara dan observasi untuk mengukur perubahan keterampilan dan hasil budidaya pasca penerapan teknologi. Hasilnya menunjukkan bahwa teknologi nano bubble secara signifikan meningkatkan kualitas air dan mempercepat pertumbuhan ikan, serta meningkatkan keterampilan peserta dalam pengoperasian dan pemeliharaan sistem sebesar 80%. Peningkatan keterampilan ini berkontribusi pada peningkatan produktivitas perikanan di kawasan tersebut, sekaligus menjadi model untuk pengelolaan perikanan air tawar di wilayah Palangka Raya.Abstract: The KKSS Palangka Raya Community faces challenges in freshwater fish farming, including poor water quality and suboptimal fish growth, which hinder aquaculture productivity. This community service program aimed to enhance the skills of 18 community members in applying nanobubble technology as an innovative solution. The methods employed included socialization, counseling, focus group discussions (FGD), and hands-on practice in applying the technology in the community's fishponds. Evaluation was conducted through interviews and observations to measure changes in skills and farming outcomes after the technology's implementation. The results indicated that nanobubble technology significantly improved water quality and accelerated fish growth, while also enhancing participants' skills in operating and maintaining the system by 80%. This skill enhancement contributed to increased aquaculture productivity in the area and serves as a model for freshwater fishery management in the Palangka Raya region.
Optimasi Tablet Levofloksasin Immediate Release Menggunakan Disintegran Sodium Starch Glycolate (SSG) dan Pengisi Laktosa dengan Metode Simplex Lattice Design (SLD) Shesanthi Citrariana; Akhmad Kharis Nugroho; Yahya Febrianto; Defilia Anograh Riani
JURNAL ILMIAH FARMASI SIMPLISIA Vol. 3 No. 2 (2023): Desember 2023
Publisher : Jurusan Farmasi, Politeknik Kesehatan Kementerian Kesehatan Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/jifs.v3i2.459

Abstract

Levofloksasin adalah antibiotik yang digunakan dalam terapi utama infeksi paru, juga merupakan sediaan farmasi yang memiliki penerimaan yang baik oleh pasien. Tablet immediate release memerlukan super disintegran yang merupakan eksipien dalam formulasi, perbedaan eksipien yang digunakan dapat memengaruhi bioperformance dari tablet. Optimasi formula digunakan sebagai metode untuk menentukan komposisi eksipien dalam formula. Penelitian ini bertujuan untuk melakukan optimasi formula tablet levofloksasin dengan metode simplex lattice design menggunakan sodium starch glycolate sebagai superdisintegran. Pembuatan tablet dilakukan dengan proses granulasi basah dan dikempa kemudian dilakukan pengujian sifat fisik berupa kekerasan, kerapuhan, waktu hancur dan disolusi efisiensi pada waktu ke 60 menit. Optimasi nilai prediksi dilakukan dengan cara observasi dan dibandingkan nilai responnya menggunakan one sample t-test. Hasil penelitian menunjukan bahwa perbedaan nilai SSG terlihat signifikan pada waktu hancur dengan nilai p<0,05 (0,0056). Hasil formula optimal dengan nilai desirability 0,811 berada pada komposisi SSG sebanyak 8mg/tablet. Pengujian konfirmasi memberikan hasil bahwa antara nilai prediksi vs observasi memberikan nilai yang tidak berbeda p>0,05. Dapat disimpulkan bahwa tablet levofloksasin yang diformulasikan memberikan nilai yang memnuhi kriteria baik sifat fisik dan efisiensi disolusi.
Gambaran Penjualan Obat Swamedikasi di Apotek Karomah Palangka Raya saat Pandemi Covid-19 Tahun 2021 Citrariana, Shesanthi; Paramawidhita, Risqika Yuliatantri
Sinteza Vol. 3 No. 1 (2023): February
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v3i1.7843

Abstract

Swamedikasi diartikan sebagai pemilihan dan pemanfaatan obat-obatan untuk mengobati gejala atau penyakit yang dikenali sendiri. Provinsi Kalimantan Tengah memiliki prevalensi swamedikasi yang tinggi yaitu 89,46%. Peningkatan minat masyarakat terhadap swamedikasi meningkat karena pandemi COVID-19. Penelitian ini bertujuan untuk melihat gambaran penjualan obat swamedikasi di Apotek Karomah saat pandemi COVID- 19 berlangsung. Pengumpulan data penjualan dilakukan dengan melihat pada SIM (Sistem Informasi Management) berbasis computer pada Juli – Agustus 2021. Hasil penelitian menunjukan bahwa tiga besar penjualan berdasarkan jenis obat di Apotek Karomah berupa Batuk&Flu sebanyak 1956 item (24,48%), Jamu&Minuman sebanyak 1482 item (18,55%), dan Alkes sebanyak 993 item (12,43%). Penjualan sepuluh besar (Top 10) berdasarkan item/ merk obat ditempati oleh komix batuk sebanyak 1236 item, madu TJ sebanyak 718 item, dan masker sebanyak 554 item. Total omzet penjualan pada Bulan Juli adalah Rp 49.068.000,- dan terlihat menurun pada Bulan Agustus Rp 43.944.000,-. Dari hasil penelitian ini dapat disimpulkan bahwa pandemi COVID-19 memberikan dampak penjualan obat swamedikasi di Apotek Karomah Kota Palangka Raya terutama obat-obat yang berkaitan dengan penurunan gejala COVID-19 dan peningkatan imunitas tubuh. 
Bahan Tambahan dalam Sediaan Tablet: Review Pratiwi, Puspa Dwi; Citrariana, Shesanthi; Gemantari, Baiq Maylinda
Sinteza Vol. 3 No. 2 (2023): August
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v3i2.17472

Abstract

Tablets are solid pharmaceutical dosage form without or with suitable excipients by press or compression manufacturing process. The excipient chosen can influence the product performance (physical properties and stability) and bioavailability. All excipients must be optimally selected to get the optimal formula of tablet dosage form. This article review aims to overview of excipient in tablet dosage form and their role in formulating tablet dosage form. this review article was written based on literature studies from electronic databases such as PubMed, ScienceDirect, and Google Scholar which contain related information using keyword in Indonesian or English use article published in 2013-2023. excipients in tablet dosage form are fillers or diluents, disintegrants, lubricants, preservatives, flavors, sweeteners, coloring, and coating agents. These excipients added to tablet dosage form to facilitating the process of manufacture tablet dosage form, increasing stability and effectiveness of active pharmaceutical ingredients in tablet. The conclusion of this review, there are many classification of tablet excipients which is different function to get compendial requirements of tablet dosage form.
Inovasi Pengembangan Teknologi Sistem Otomatis Pengendalian Hama di Kebun Buah Kelompok Tani Harapan Kota Palangka Raya Arsana, Mu afa; Ngazizah, Febri Nur; Wilda, Robiatul Witari; Adi, Mika; Jipasca, Elon; Febrianto, Yahya; Alfanaar, Rokiy; Rahman, Sudarman; Suprayogi, Thathit; Citrariana, Shesanthi; Fatiqin, Awalul
Al-Khidmah Jurnal Pengabdian Masyarakat Vol. 5 No. 3 (2025): SEPTEMBER-DESEMBER
Publisher : Institute for Research and Community Service (LPPM) of the Islamic University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56013/jak.v5i3.4923

Abstract

The Community Service Program was carried out at the Harapan Farmers Group, Kereng Bangkirai Sub-district, Palangka Raya City, as an effort to provide innovative solutions to pest attack problems that often reduced fruit farm productivity. Previously, farmers had relied on manual pesticide spraying, which required considerable time, labor, and cost, and posed health risks. To address this challenge, the service team from the University of Palangka Raya developed an automated pest control system that was able to regulate pesticide spraying independently and efficiently. The activities were conducted through stages of socialization, training, and system mapping of automation in the fruit farm area, involving members of the farmers group actively. The implementation results showed an increase in participants’ understanding of the technology by 30–40 percent, improved efficiency in pesticide use by up to one-third compared to manual methods, and a reduction in working time by nearly 50 percent. This activity not only improved farmers’ skills and productivity but also served as a concrete step toward the implementation of sustainable smart farming in Palangka Raya through collaboration between the university and the community.
Peningkatan Kapasitas Produksi Gummy Candy Sehat Berbasis Buah Lokal melalui Pelatihan dan Transfer Teknologi Citrariana, Shesanthi; Ayu, Regina Wahyudyah Sonata; Riani, Defilia; Desindria, Galang Rizdho; Yosaeunike, Vitatani; Febrianto, Yahya; Alfanaar, Rokiy; Rahman, Sudarman; Suprayogi, Thathit; Arsana, Mu afa; Fatiqin, Awalul
Al-Khidmah Jurnal Pengabdian Masyarakat Vol. 5 No. 3 (2025): SEPTEMBER-DESEMBER
Publisher : Institute for Research and Community Service (LPPM) of the Islamic University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56013/jak.v5i3.4924

Abstract

The problem of fruit waste due to oversupply in agritourism, which causes economic losses and environmental burdens, is the focus of this community service activity. The program aims to enhance partners' capacity through training and technology transfer in producing healthy gummy candy from local fruits. Implementation methods included observation, socialization, practical training, and evaluation involving 20 participants from Agrowisata Cipta Rasa Pak Slamet. The results showed significant improvement in three aspects: conceptual and material understanding (85-90%), procedural skills (95%), and partner enthusiasm and motivation (100%). The implementation of green economy principles was achieved through the conversion of fruit surplus into high-value products with extended shelf life. This program successfully established a strong production foundation while creating a sustainable green value chain. It is concluded that the participatory training approach effectively empowers partners and is ready to be replicated in other locations with similar problems. Program sustainability is ensured through partner commitment and an agreed-upon production monitoring plan.
Co-Authors Adi, Mika Adistia P, Allaya Ahmad Irawan, Ahmad Akhmad Kharis Nugroho Alfanaar, Rokiy Anograh R, Defilia Ardi Akbar Tanjung Ari Wibowo Arsana, Mu afa Arsana, Mu’afa Purwa Arsana, Mu’afa Purwa Awalul Fatiqin Awumistiko Awumistiko Ayu, Regina Wahyudyah Sonata Ayuchecaria, Noverda Baiq Maylinda Gemantari Bambang Hernawan Nugroho Chuchita Dea Betriksia Decenly Decenly Decenly, Decenly Defilia Anogra Riani Defilia Anograh Riani Desindria, Galang Rizdho Efriyana Oksal Efriyana Oksal Elphasa H, Shavira Emma Ayudia Noriadita Endang Lukitaningsih Erni Dwi Puji Setyowati, Erni Dwi Puji Fatiqin, Awalul Fauziah, Anisa Rahma Gerung, Jenny Blessia Gintoro, Atilla Dian Dewanti Gunawan, Yohanes E Gunawan, Yohanes Edy Guntur Satrio Pratomo Hakim, Shavira Alpasa Halida Suryadini Haq, Muhammad Hasanul Ita Nurma Sari Ita Nurma Sari Jipasca, Elon June N, Franz Kaharati, Jonathan Kalalinggi, Septaria Yolan Krissilvio, Eka Jonathan Kurniawan, Yehezkiel Steven M Munawwarah Ma'rifah, Siti Mariasa, Joice Cleriska Melliani Melliani Muhammad Dawam Muhammad Priyadi Mu’afa Purwa Arsana Mu’afa Purwa Arsana Ngazizah, Febri Nur Nur Hidayat Oktavia Indrati, Oktavia Parametta, Vidya Pritaningtyas, Nazifa Wulan Puspa Dwi Pratiwi Puspa Dwi Pratiwi Rahman, Ansori Rahman, Sudarman Rahmman, Sudarman Reny Nadya Oktari Riani, Defilia Risqika Yulia Tantri Paramawidhita Rizki Rachmad Saputra Rokiy Alfanaar Shodri, Muhammad Rifqi Simajuntak, Ruth Riama Siti Sunariyati Sulistia, Tiya Thathit Suprayogi Thathit Suprayogi Tri Megawati Wahyu Nugroho Wilda, Robiatul Witari Yahya Febrianto Yahya Febrianto Yohanes Edy Gunawan Yosaeunike, Vitatani Yulita, Elia Zimon Pereiz