Article Per Year (5 Year)
p-Index From 2021 - 2026
4.615
P-Index
This Author published in this journals
All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Jurnal Kedokteran Brawijaya Althea Medical Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Biota Jurnal Florea Berkala Kedokteran BIOMA International Journal of Applied Biology Jurnal Ilmiah Kedokteran Wijaya Kusuma Briliant: Jurnal Riset dan Konseptual The Indonesian Journal of Infectious Diseases Care : Jurnal Ilmiah Ilmu Kesehatan Majalah Kedokteran Andalas INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Jurnal Abdidas Eureka Herba Indonesia Journal of Community Development Jurnal Pengabdian Masyarakat Kedokteran Sinnun Maxillofacial Journal Stigma : Jurnal Matematika dan Ilmu Pengetahuan Alam Unipa JAPI: Jurnal Akses Pengabdian Indonesia Journal of Community Services Jurnal Pengabdian Masyarakat Prosiding Seminar Nasional Kusuma Prosiding Seminar Nasional COSMIC Kedokteran
Putu Oky Ari Tania
Bagian Biomedik Penelitian Biomolekuler Fakultas Kedokteran Universitas Wijaya Kusuma Surabaya
Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

Published : 38 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 38 Documents
Search

 1   2   3   4 
Analisis dan Prediksi Uji Biokimia Fungsi Liver pada Pemberian Ekstrak Kunyit Putih (Curcuma zedoaria) Setelah dan Sebelum Paparan Parasetamol Dosis Tinggi Puja Ayu Misuari; Satya Yudhayana; Putu Oky Ari Tania; Dorta Simamora
Majalah Kedokteran Andalas Vol 45, No 3 (2022): Online July 2022
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v45.i3.p308-315.2022

Abstract

Kegagalan fungsi liver yang akut banyak disebabkan oleh penyalahgunaan parasetamol atau Acetaminophren. Parasetamol dosis tinggi menyebabkan nekrosis liver dan kegagalan fungsi liver. Pada liver, parasetamol diubah menjadi N-acetyl-para-benzo-quinine imine (NAPQI), yang meningkatkan stress oksidatif dan disfungsi mitokondria. Disfungsi liver ditandai dengan peningkatan enzim SGOT dan SGPT serta rasio keduanya. Penggunaan rimpang Curcuma zedoaria dipercaya dapat memberikan proteksi terhadap liver. Kandungan antioksidan fenolik di dalamnya memiliki kemampuan menangkal radikal hidroksil, sehingga diharapkan dapat memulihkan stres oksidatif, melindungi terhadap paparan parasetamol. Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak rimpang Curcuma zedoaria setelah dan sebelum pemberian parasetamol dosis yang tinggi, melalui kadar enzim SGOT dan SGPT, serta rasio keduanya. Penelitian ini menggunakan 24 ekor tikus jantan dewasa (Rattus norvegicus) yang dibagi menjadi 4 kelompok yaitu KN; KP yang diberikan parasetamol dosis tinggi 1,35 g/ Kg BB; kelompok perlakuan yang diberi ekstrak Curcuma zedoaria dosis 105mg/ 200 g BB pada 2 jam sesudah (P1) dan sebelum pemberian parasetamol (P2). Analisis data menggunakan uji Kruskal-Wallis dan ANOVA dengan nilai p sebesar 0,019 dan 0,027. Penurunan kadar SGOT dan SGPT terendah pada kelompok P2 yaitu 156,06 IU dan 151,90 IU. Rasio SGOT/SGPT tertinggi pada KP sebesar 2,21 IU/L.
Mekanisme Escape dan Respon Imun innate terhadap Candida albicans Putu Oky ari Tania
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 9, No 1 (2020): MARET 2020 available online since April 2020
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (306.01 KB) | DOI: 10.30742/jikw.v9i1.747

Abstract

Candidiasis is an infection caused by fungal Candida albicans. The incidence of candidiasis is pretty high in Indonesia. Candida albicans develop their pathogenicity by several ways so that it can invade and escape from the immune system. The host’s immune system must always be vigilant to recognized antigen through various receptors, activation of the transduction pathway and activation of various immune cells. But as organisms that struggle to survive, Candida also develops mechanisms to escape the immune response. There are so many articles have written the immune response against candidiasis, this review aims to understand more and updating information about the biological processes of pathogenicity of fungi and the mechanism of Candida albicans in escaping immune responses, the role of each innate molecule and immune cell, and clinical aspect to Candida albicans infections. We already facing the big challenges against therapy of fungal infection, so by understanding the escape mechanism of Candida albicans, it is possible to developed antifungal or Candida vaccine in the future, therefore the incidence of candidiasis can be suppressed.
Interleukin-6 (IL-6) Level as an Indikator of Progresivity Rheumatoid Arthritis (RA) Disease Putu Oky Ari Tania; Dorta Simamora; Wahyuni Dyah Parmasari; Febtarini Rahmawati
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 3, No 1 (2014): Edisi Maret 2014
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (255.884 KB) | DOI: 10.30742/jikw.v3i1.44

Abstract

Rheumatoid Arthritis (RA) is autoimmune disease that attacks joints and synovial tissues. Rheumatoid Arthritis is characterized by inflammation that involves production of cytokines such as Interleukin 6 (IL-6). Increasing of interleukin 6 has correlation with activity and progressivity of the disease. This research was designed to know whether IL- 6 could be used as indicator progressivity of RA. The method that used for measuring IL-6 level is ELISA (Enzyme Linked Immunosorbent Assay), using the principle antigen-antibody binding. In early stage there were 9 persons (S01, S02, S03, S04, S07, S08, S09, S10 and S14) with of IL-6 level (mean : 3.640 pg/mL), intermediate stage there were 3 persons (S06, S13 and S15) with IL-6 level (mean : 12.453 pg/mL), late stage : 3 persons (S05, S11 and S12) with IL-6 level (mean : 59.349 pg/mL).
Potency of Ethanol Extract Celery (Apium graveolens L.) Stalk as Anti-Cholesterol I Made Subhawa Harsa; Andiani Andiani; Harsono Wiradinata; Putu Oky Ari Tania
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 11, No 2 (2022): EDISI SEPTEMBER 2022
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (277.864 KB) | DOI: 10.30742/jikw.v11i2.2014

Abstract

Increasing levels of blood cholesterol is one of the risk factors for atherosclerosis. Currently, experts have been trying used herbal medicine as an alternative treatment of atherosclerosis. One of the highlights is the use of celery stalks. Celery is generally used as a flavouring dish. In addition, celery stalks are believed able to reduce cholesterol levels because they contain flavonoids, tannins, and saponins. This study was aim to determine the effect of celery stalk ethanol extract to reduce LDL an increase of HDL level in rats after fed high-fat diet. Randomized Post Test Only Control Group Design was used to measure the HDL and LDL blood serum levels of male Wistar (Rattus norvegicus) rats fed a high-fat diet. This study was used 27 male Wistar rats (Rattus norvegicus) divided into 3 groups; K1 was only given regular feed and water, K2 was given a high-fat diet and water, K3 was given a high-fat diet and celery stalk extract at a dose of 75mg/kg BW/day for 14 days. The data were analysed by ANOVA test and Tukey HSD test. The results of the ANOVA test showed a significance value of p-value of LDL = 0.000 and HDL p-value = 0.536. Celery stalk extract (Apium graviolens L) had an effect on decreasing LDL levels but not on increasing HDL blood serum levels of white Wistar rats (Rattus norvegicus) given high-fat diet.
Intense relationship of blood pressure and stadium of chronic kidney disease at early diagnosis Putra, Wisnu Pratama; Tania, Putu Oky Ari; Njoto, Ibrahim; Suryawati, Sianny
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 13, No 2 (2022): December 2022
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (341.899 KB) | DOI: 10.30659/sainsmed.v13i2.20235

Abstract

Chronic kidney disease (CKD) is a pathological stage with multiple causes that is characterised by a very high level of urea in the body because the kidneys are unable to balance the metabolism of fluids and electrolytes. Previous research has demonstrated that high blood pressure is one of the causes of chronic kidney disease. This study was conducted to determine the relationship between blood pressure and the initial stage of chronic kidney disease. observational study of Ninety patients with chronic kidney disease (CKD) at the RSUD Dr. Soeroto, Ngawi participated in this cross-sectional. Subjects were required to have CKD stages I-IV, high blood pressure, to be hospitalised for the first time at RSUD dr Soeroto, Ngawi, and to have never been treated for hypertension. This study employed the Spearman rank test, which was analysed by SPSS (p<0.05). 64.5% of patients with chronic kidney disease have reached stage V. In contrast, 47.8% of patients with chronic kidney disease have stage 2 hypertension. The Spearman Rank test revealed a p-value of 0.000 (<0.05) between blood pressure and the stage of chronic kidney disease at the time of initial diagnosis in patients with chronic kidney disease. The correlation coefficient has a value of 0.638, making it a strong correlation. There is a strong correlation between blood pressure and the stage of chronic kidney disease at the initial diagnosis of chronic kidney disease patients at the RSUD Dr. Soeroto, Ngawi.
Edukasi dan Pembagian Vitamin C Untuk Peningkatan Sistem Imunitas Pada Masyarakat Desa Prambangan, Gresik Ayly Soekanto; Sukma Sahadewa; Emillia Devi Dwi Rianti; Erny Erny; Fuad Ama; Agusniar Furkani Listyani; Putu Oky Ari Tania; Endrayana Putut Laksminto Emanuel
Jurnal Pengabdian Masyarakat Kedokteran Vol 2, No 3 (2023): September
Publisher : Fakultas Kedokteran, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/abdimasku.2.3.120-127

Abstract

Pandemi yang berlangsung pada tahun 2020 sampai dengan 2023 yaitu terjadinya Covid-19 yaitu penyakit infeksi yang disebabkan virus corona. Pandemi ini menyebabkan jumlah penderita yang terus bertambah. Indonesia yang merupakan negara terdampak wabah saat ini. Penyakit infeksi sangat bergantung pada sistem imunitas dari masing-masing individu. Salah satu cara untuk meningkatkan sistem pertahanan tubuh dapat dilakukan dengan memberikan nutrisi dan bahan yang terdiri komplek dari senyawa enzim, mineral, senyawa fenolik , vitamin dan flavonoid yang dapat menghambat perlepasan histamin dengan cara stabilisasi selaput sel lipid. Vitamin C berfungsi membuang radikal bebas kuat dalam plasma, melindungi sel dari zat oksidatif yang merusak karena radikal bebas ROS (reactive oxygen species). Upaya ini dapat meningkatkan sistem imunitas tubuh terutama imunitas selular. Oleh karena itu pengabdian kepada masyarakat ini bertujuan untuk memberikan edukasi dan pemberian vitamin C dalam rangka meningkatkan sistem imunitas warga.
Anti-Proliferative Compound Candidate of White Turmeric (Curcuma zedoaria) Putu Oky Ari Tania; Candra Rini Hasanah Putri; Ayling Sanjaya; Titiek Sunaryati; Deddy Hartanto; Erlix R Purnama; Meivy Isnoviana
Biota Vol 9 No 2 (2023): Jurnal Biota 2023
Publisher : Faculty of Science and Technology Universitas Islam Negeri Raden Fatah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19109/Biota.v9i2.13746

Abstract

Malignant disease or cancer progression burden the community after decades. This tumor formation or tumorigenesis involves cell proliferation. Protein Kinases (MAPK9s) is key proteins of regulating the growth and viability of cells physiologically and pathologically. Rhizomes of Curcuma zedoaria or zedoary or white turmeric is used as a health supplement. The aim of this study was to obtained candidate proteins for anti-proliferative using the docking method between the protein MAPK9 and the active compound obtained from the crude extract of white turmeric i.e. demethoxycurcumin, curcumenol and germacrone. The result s hows that complex MAPK-demethoxycurcumin have the lowest binding affinity -8.4 Kkal/mol, while MAPK-curcumenol was -8 Kkal/mol, and MAPK-Germacrone was -6.2 Kkal/mol, it determined the potential activity cell proliferation.
Imunitas Pasien Asimtomatis sebagai Super-spreader Covid-19 Putu Oky Ari Tania
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 8 No. 3 (2021): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universi
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v8i3.183

Abstract

Indonesia sebagai negara dengan penduduk berusia 15-44 tahun sebanyak 46,87% dari total penduduk, terdapat lonjakan kasus positif COVID-19 yang mencapai 797.723 kasus per 7 Januari 2021. Kelompok usia muda diduga menjadi kelompok penyumbang kasus infeksi tanpa gejala atau asimtomatis. Pasien asimtomatis umumnya tidak menyadari bahwa mereka berpotensi untuk menularkan infeksi dari SARS-CoV-2 penyebab COVID-19. Penulisan literatur review ini menggunakan metode pencarian literatur dari Pubmed dengan kata kunci asymptomatic, COVID-19, cytokine, inflammation. Studi ini bertujuan untuk menelaah sistem imun dari pasien asimomatis dan mengapa pasien tersebut menunjukkan gejala yang lebih ringan.
Edukasi efektivitas vitamin E pada warga Asem Jajar Surabaya: Edukasi efektivitas vitamin E pada warga Asem Jajar Surabaya Emilia Devi Dwi Rianti; Ayly Soekanto Ayly Soekanto; Putu Oky Ari Tania Putu Oky Ari Tania
JCS Vol. 5 No. 3 (2023): Edisi Oktober 2023
Publisher : Akademi Kebidanan Tahirah Al Baeti Bulukumba

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57170/jcs.v5i3.102

Abstract

Vitamin E is very important for skin health, because as a bioactive compound, it is very important in the pathogenesis of the skin, although it shows a decrease in vitamin E levels in patients who experience skin diseases. The method used in community service is providing education about the effectiveness of vitamin E on skin health, and administering vitamin E. There were 35 residents who attended the education. The teaching aids used are in the form of a Flichat describing knowledge about improving skin health and Vitamin E. Evaluation of community service activities, namely; Women in the RT environment. 03 Asem Jajar Surabaya received counseling on maintaining healthy skin, understanding and knowing the benefits of vitamins. The results and discussion in using a device to measure moisture or skin oil levels with the MR213 LCD Monitor, which is an LCD Digital Skin Detector device, are 31.43% aged 41-55 years and 2.9% aged 81-90 years. The skin moisture of the residents showed no influence based on age, because some residents aged 60 years had skin humidity of 60%, and those aged 55 years had humidity of 45%. The high vitamin E content functions to help care for the skin. Providing vitamin E to residents aims to ensure that residents consume vitamin E for healthy skin. The conclusion of the education on the effectiveness of vitamin E for residents of RT.03 Asem Jajar Surabaya is very useful, because residents lack knowledge about skin care and skin benefits.
Preface March 2024 Putu Oky Ari Tania
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 13, No 1 (2024): March 2024
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v13i1.3656

Abstract

Co-Authors AFAF BAKTIR Agusniar Furkani Listyani Agusniar Furkani Setiyawati Ahista Saskirana Putri Ahnaf Farel Al Raihaan akhmad sudibya, akhmad Amirotul Khifana Andiani Andiani Andra Agnez Al Aska Athaya Azalia Yasirah Ayling Sanjaya Ayly Soekanto Azka, Andra Agnes Al Cahyadi, I Kadek Angga Dwi Candra Rini Hasanah Putri Candra Rini Hasanah Putri Colin, Muhammad Deddy Hartanto Dorta Simamora Emanuel, Endrayana Putut Laksminto Emilia Devi D. Rianti Emilia Devi Dwi Rianti Emilia Devi Dwi Rianti Emilia Devi Dwi Rianti Emillia Devi Dwi Rianti, Emillia Devi Dwi Enny Willianti, Enny Erlix R Purnama Erny Erny Erny Erny Fadilla Lutvi Aryanti Febtarini Rahmawati Febtarini Rahmawati Fuad Ama Furkani, Agusniar Hardiyono Hardiyono Hardiyono Hardiyono Hardiyono Hardiyono HARMAN AGUSAPUTRA Harsono Wiradinata Haru Setiawan I Kadek Putra Dwipayana I Made Subhawa Harsa Ibrahim Njoto, Ibrahim Inawati Inawati, Inawati Indra Firismanda Dermawan Kadek Adi Sudarmika Ketut Ayesha Edelwise Prayoga Listyawati, Agusniar Furkani Loo Hariyanto Raharjo, Loo Hariyanto Lusiani Tjandra Marcela Anindita Masfufatun Masfufatun Masfufatun Maverick Nathanael Adirangga Meivy Isnoviana Muhammad Collin Nadila, Sucia Ni Kadek Evita Vara Rosieana Ni Made Ayu Gea Niquita Noer Kumala Indahsari, Noer Kumala Nugraha, Wima Handika Nur Sri Wahyuni Olivia Rahayu Ramadhani Pramita Laksitarahmi Isrianto Puja Ayu Misuari Puja Ayu Misuari Putra, Wisnu Pratama Putut Laksminto Emanuel Rini Purbowati Sakri, Brian Manggala Satya Yudhayana Satya Yudhayana Sianny Suryawati, Sianny Sudarmika, Kadek Adi Sukma Sahadewa, Sukma Syeira Rigita Noptavia Theodora Theodora Titiek Sunaryati Titiek Sunaryati Titiek Sunaryati, Titiek Wahyuni Dyah Parmasari, Wahyuni Dyah