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<![CDATA[IbM Gerakan Masyarakat Petani Atasi Racun (GEMPAR) di Kabanjahe Kabupaten Karo ]]>
<![CDATA[Eka Lestari Mahyuni]]>;
<![CDATA[R. Hamdani Harahap]]>;
<![CDATA[Urip Harahap]]>;
<![CDATA[Nurmaini Nurmaini]]>
<![CDATA[ Aksiologiya: Jurnal Pengabdian Kepada Masyarakat Vol 6, No 4 (2022): November ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Surabaya ]]>
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DOI: 10.30651/aks.v6i4.6658
<![CDATA[Keracunan pestisida merupakan suatu kejadian yang perlu diperhatikan khususnya bagi petani yang menggunakan pestisida. Fenomena keracunan umumnya disebabkan karena perilaku penggunaan pestisida yang tidak sesuai prosedur dan berisiko. Kegiatan PPM ini merupakan salah satu kegiatan pemberdayaan masyarakat untuk mengurangi risiko keracunan pestisida melalui gerakan sosial yang disebut dengan GEMPAR (Gerakan Masyarakat Petani Atasi Racun). GEMPAR merupakan gerakan sosial yang terdiri dari delapan aksi sebagai gerakan petani untuk mengurangi risiko keracunan akibat penggunaan pestisida. Aksi GEMPAR meliputi bagaimana mengenali bahaya racun pestisida dan gejala keracunan; menggunakan pelindung diri yang lengkap selama menggunakan pestisida; memperhatikan arah angin selama menyemprot; menyimpan pestisida di tempat yang aman dan tertutup; membuang sisa wadah pestisida di tempat yang tertutup; melaporkan keluhan bila mengalami gejala keracunan; dan beralih menggunakan pestisida alami dan meninggalkan pestisida kimia sintetis. GEMPAR yang dilaksanakan dalam kegiatan PPM ini dilakukan sebagai peningkatan edukasi petani dan menjawab kendala penerapan GEMPAR melalui kegiatan talk show. Kegiatan ini mendukung promosi aksi GEMPAR yang dilakukan petani sehingga dapat menunjang kesejahteraan dan perekonomian petani. Disamping dapat menghindari risiko keracunan juga dapat menyehatkan masyarakat petani dengan produk pertanian yang bebas pestisida.]]>
<![CDATA[Immunomodulatory Effects of Phaleria macrocarpa Leaf Extract in Normal And Cyclophosphamides Induced in Wistar Rats ]]>
<![CDATA[Febriady, Andy]]>;
<![CDATA[Harahap, Urip]]>;
<![CDATA[Yuandani, Yuandani]]>
<![CDATA[ Indonesian Journal of Pharmaceutical and Clinical Research Vol. 5 No. 2 (2022): Indonesian Journal of Pharmaceutical and Clinical Research ]]>
Publisher : <![CDATA[Talenta Publisher ]]>
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DOI: 10.32734/idjpcr.v5i2.11271
<![CDATA[Abstract. Cyclophosphamide is an antineoplastic drug belonging to the alkylating agents commonly used in treating cancer. However, the use of cyclophosphamide causes a decrease in the body's immune system by reducing lymphocyte proliferation. The curent study was conducted to evaluate the immunomodulatory effect of ethyl acetate extracts of the leaf of the P. macrocarpa (EEADMD) and the ethanol extracts of the leaf of the P. macrocarpa (EEDMD) in normal and cyclophosphamide induced rats. This study used rats classified into two major groups: normal rats and rats induced by cyclophosphamide which were then given P. macrocarpa leaf extract until day 14. On day 4, the test animals were infected with 1% Staphylococcus aureus suspension in. Induced with cyclophosphamide 70 mg/kg BW was carried out on the 8th and 13th days, and then the immunomodulatory activity was tested using total leukocyte analysis, leukocyte differential, and delayed type hypersensitivity response. The results showed that EEDMD 400 mg/kg BW Â in normal rats and EEDMD 100 mg/kg BW in cyclophosphamide induced rats could increase total leukocytes and leukocyte differential with a significant difference to the negative group (p <0.05). The results of the delayed hypersensitivity response test of EEADMD and EEDMD at a dose of 100 mg/kg BW with cyclophosphamide induction and normal rats could give an increase in rat paw volume with a significant difference to the negative group (p <0.05). This study shows that EEADMD and EEDMD have an immunomodulatory effect on increasing total and differential leukocytes and leukocyte differential and delayed type hypersensitivity response.]]>
<![CDATA[Antioxidant activity of 1.3-bis(p-hydroxyphenyl)urea by CUPRAC and FRAP methods ]]>
<![CDATA[Satria, Denny]]>;
<![CDATA[Rifda Amaliya Ma’ruf]]>;
<![CDATA[Syukur Berkat Waruwu]]>;
<![CDATA[Urip Harahap]]>;
<![CDATA[Hari Purnomo4]]>
<![CDATA[ Indonesian Journal of Pharmaceutical and Clinical Research Vol. 6 No. 1 (2023): Indonesian Journal of Pharmaceutical and Clinical Research ]]>
Publisher : <![CDATA[Talenta Publisher ]]>
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DOI: 10.32734/idjpcr.v6i1.17768
<![CDATA[An imbalance in the number of free radicals produced in the body can result in oxidative stress. Excessive oxidative stress can lead to chronic inflammation, which in turn can lead to most chronic diseases. Inflammation is related to oxidation through increased reactive oxidative stress, which can target modulators associated with inflammation, such as inflammatory cytokines. Antioxidants can inhibit or stop oxidation by protecting the body and neutralizing free radicals. 1.3-bis(p-hydroxyphenyl)urea is a modification of p-aminophenol and has hepatotoxic side effects such as those caused by acetaminophen. This compound can relieve pain, is anti-inflammatory, and has fewer side effects. This research was conducted to evaluate the antioxidant activity of 1.3-bis(p-hydroxyphenyl)urea using the CUPRAC (Cupric Ion Reducing Antioxidant Capacity) method and the FRAP (Ferric Reducing Antioxidant Power) method. The results of the CUPRAC method research show that the 1.3-bis(p-hydroxyphenyl)urea compound has an IC50 value of 4.40 ± 0.07 μg/mL. Meanwhile, the FRAP method was 29.36 ± 1.20 μg/mL. Apart from suppressing inflammation, this compound has the potential to be an antioxidant compound.]]>
<![CDATA[Analysis of the Application of Pharmaceutical Service Standards and Patient Satisfaction with Accreditation Status and Types of Services ]]>
<![CDATA[Tarigan, Betharina Br]]>;
<![CDATA[Dalimunthe, Aminah]]>;
<![CDATA[Nasution, Azizah]]>;
<![CDATA[Harahap, Urip]]>;
<![CDATA[Khairunnisa, Khairunnisa]]>
<![CDATA[ Journal La Medihealtico Vol. 4 No. 2 (2023): Journal La Medihealtico ]]>
Publisher : <![CDATA[Newinera Publisher ]]>
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DOI: 10.37899/journallamedihealtico.v4i2.846
<![CDATA[Accreditation is a method to improve the quality of health services, so that it is expected that the services provided are in accordance with established regulations. This study aims the implementation of Pharmaceutical Service Standards (PCSs) and patient satisfaction on accreditation status and types of PHCs in Deli Serdang Regency, Sumatera Utara. This descriptive analytical cross-sectional study was conducted to analyze pharmacy services at PHCs (n=34) in Deli Serdang Regency. The reference used is the Checklist for PCSs based on direct observations and interviews with the person in charge of pharmacy and the Patient Satisfaction Questionnaire. The data obtained were analyzed using SPSS version 22. The results on the value of a total score PCSs showed 41-90, with the highest level of patient satisfaction is the very satisfied category is 65.90%.The correlation test was analyzed using the Chi-Square test with a significance limit of p<0.05, the correlation of accreditation status to the implementation of PCSs showed a value of p=0.304, the correlation of the type of service to the implementation of PCSs showed a value of p=0.591, the correlation of the accreditation status of PHCs to the level of satisfaction patient value showed a value of p=0.000. This study concluded that the accreditation status of the PHCs does not affect implementation of PCSs, the type of PHCs service does not affect implementation of PCSs and the accreditation status of the PHCs has an effect on the level of patient satisfaction in Deli Serdang Region, Sumatera Utara.]]>
<![CDATA[EKSTRAK ETANOL DAUN SIRIH MERAH (Piper crocatum) MENURUNKAN KADAR GULA DARAH MENCIT DIABETES ]]>
<![CDATA[Ambali Azwar Siregar]]>;
<![CDATA[Urip Harahap]]>;
<![CDATA[Mardianto Mardianto]]>
<![CDATA[ Jurnal Ilmiah Manuntung Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung ]]>
Publisher : <![CDATA[jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda ]]>
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DOI: 10.51352/jim.v1i1.10
<![CDATA[Diabetes mellitus is one of desease that have a large population and trend to increase. sulfonylurea and biguanide are almost used treatment but have unexpected side effects. The research still necessary to seek alternative medicine, such as Piper crocatum.This study aimed to determine the effect of ethanol extract of red betel leaves on blood sugar levels and body weight of mice (Mus musculus L.) diabetes. This riset was started to produce simplicia and drilled become powders, continued extract with 70% ethanol. The extract was evaporated with rotary evaporator until obtaine crude extract. And then screen it that determine phytochemical. To continued test on tolerance of level of glucose then mice diabetes induced aloxan.In summary, extract of red betle ethanolic has contained alkaloid, quercetin flavonoid, steroid and fenolic compounds and decreased level of glucose in blood mice diabetes. Besides, it can reduce lose of weight symptom.]]>
<![CDATA[IbM Gerakan Masyarakat Petani Atasi Racun (GEMPAR) di Kabanjahe Kabupaten Karo ]]>
<![CDATA[Mahyuni, Eka Lestari]]>;
<![CDATA[Harahap, R. Hamdani]]>;
<![CDATA[Harahap, Urip]]>;
<![CDATA[Nurmaini, Nurmaini]]>
<![CDATA[ Aksiologiya: Jurnal Pengabdian Kepada Masyarakat Vol 6 No 4 (2022): November ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Surabaya ]]>
Show Abstract
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DOI: 10.30651/aks.v6i4.6658
<![CDATA[Keracunan pestisida merupakan suatu kejadian yang perlu diperhatikan khususnya bagi petani yang menggunakan pestisida. Fenomena keracunan umumnya disebabkan karena perilaku penggunaan pestisida yang tidak sesuai prosedur dan berisiko. Kegiatan PPM ini merupakan salah satu kegiatan pemberdayaan masyarakat untuk mengurangi risiko keracunan pestisida melalui gerakan sosial yang disebut dengan GEMPAR (Gerakan Masyarakat Petani Atasi Racun). GEMPAR merupakan gerakan sosial yang terdiri dari delapan aksi sebagai gerakan petani untuk mengurangi risiko keracunan akibat penggunaan pestisida. Aksi GEMPAR meliputi bagaimana mengenali bahaya racun pestisida dan gejala keracunan; menggunakan pelindung diri yang lengkap selama menggunakan pestisida; memperhatikan arah angin selama menyemprot; menyimpan pestisida di tempat yang aman dan tertutup; membuang sisa wadah pestisida di tempat yang tertutup; melaporkan keluhan bila mengalami gejala keracunan; dan beralih menggunakan pestisida alami dan meninggalkan pestisida kimia sintetis. GEMPAR yang dilaksanakan dalam kegiatan PPM ini dilakukan sebagai peningkatan edukasi petani dan menjawab kendala penerapan GEMPAR melalui kegiatan talk show. Kegiatan ini mendukung promosi aksi GEMPAR yang dilakukan petani sehingga dapat menunjang kesejahteraan dan perekonomian petani. Disamping dapat menghindari risiko keracunan juga dapat menyehatkan masyarakat petani dengan produk pertanian yang bebas pestisida.]]>
<![CDATA[Prevention of Pesticide Toxicity Risk through the Farmer Community Movement to Resolve Toxicity ]]>
<![CDATA[Mahyuni, Eka Lestari]]>;
<![CDATA[Harahap, R. Hamdani]]>;
<![CDATA[Harahap, Urip]]>;
<![CDATA[Nurmaini]]>
<![CDATA[ ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 5 No. 2 (2020): ABDIMAS TALENTA : Jurnal Pengabdian Kepada Masyarakat ]]>
Publisher : <![CDATA[Talenta Publisher ]]>
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DOI: 10.32734/abdimastalenta.v5i2.4889
<![CDATA[Pesticide toxicity is a phenomenon that needs to be prevented, which is generally caused by the risky behavior of using pesticides. This PPM activity is one of the community empowerment activities to reduce the risk of pesticide toxicity through the GEMPAR (Gerakan Masyarakat Petani Atasi Racun) action. GEMPAR consists of eight farmer movements to prevent the risk of toxicity due to pesticides used. The eight GEMPAR actions were applied by farmers with promotional and educational methods through the GEMPAR demonstration activities. The demonstration implementation method is presented by the farming community which is divided into three areas in Sumber Mufakat Village, namely Berhala, Simpang Sumbul, and Pasar Sumbul. Demonstrations from these three areas were contested as a form of appreciation for the community so that they could motivate the community to participate in preventing the risk of pesticide toxicity. The demonstration that displayed the messages of the eight GEMPAR movements was carried out well. Each demonstration gives special characteristics either through songs or slogans related to preventing the risk of toxicity. The community became very enthusiastic about the demonstration which could increase the participation of the farming community to use better and healthier pesticides sustainably.]]>
<![CDATA[The Prevention of Pesticide Risk Toxicity among Farmers on Food Estate Humbang Hasundutan ]]>
<![CDATA[Mahyuni, Eka Lestari]]>;
<![CDATA[Harahap, R. Hamdani]]>;
<![CDATA[Harahap, Urip]]>;
<![CDATA[Nurmaini]]>
<![CDATA[ ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 7 No. 2 (2022): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat ]]>
Publisher : <![CDATA[Talenta Publisher ]]>
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DOI: 10.32734/abdimastalenta.v7i2.7809
<![CDATA[This PPM activity is one of the community empowerment activities to increase the capacity of farmers, especially increasing safety and health behavior while using pesticides. The prevention program carried out in the form of a community movement to reduce the risk of pesticide toxicity is called GEMPAR (Gerakan Masyarakat Petani Atasi Racun). GEMPAR consists of eight action activities as a farmer movement in reducing the risk of toxicity due to the use of pesticides. GEMPAR in the PPM activity was carried out as a prevention effort which was promoted through FGD activities, demonstrations, and brainstorming. Farmers in the Food Estate are classified as farmers who work with the company so that the pattern of pesticide use is included in the regular category in determining the dose and type of pesticide used. However, the application of pesticides is still classified as very dangerous where direct contact with pesticides is very high. GEMPAR as a health solution responded very well and increased awareness of Food Estate farmers to improve pesticide use patterns. Each farmer acts as an agent of change who can comprehensively expand GEMPAR information through the promotion of the message of the eight GEMPAR actions which are divided into primary, secondary, and tertiary prevention actions.]]>
<![CDATA[The Farmer’s Personal Hygiene Improvement Through the Use of Hand Soap Gel Extract of Acem Acem Leaf ]]>
<![CDATA[Mahyuni, Eka Lestari]]>;
<![CDATA[Harahap, Urip]]>
<![CDATA[ ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 1 (2023): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat ]]>
Publisher : <![CDATA[Talenta Publisher ]]>
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DOI: 10.32734/abdimastalenta.v8i1.7810
<![CDATA[Pesticide exposure due to poor personal hygiene is very high because farmers generally contact soil, fertilizers, and pesticides which are synthetic chemicals that are harmful to health. The leaves of acem acem are a type of wild plant that is often used by farmers in Tanah Karo as a medium for cleaning hands after applying pesticides. Based on the results of laboratory tests, this leaf has properties as a pesticide cleaner so that it can be used to improve the personal hygiene of farmers. This activity is carried out by empowering the behaviour of washing hands using hand soap gel acem acem leaf extract. Farmers' awareness to improve personal hygiene begins with socialization and training provided as personal hygiene education to improve public health. Education accompanied by the movement of washing hands with hand soap gel acem acem leaf extract has given a positive contribution and appreciation and can increase the enthusiasm of farmers to improve public health.]]>
<![CDATA[The Formulation of Effervescent Granules with Oxalis dehradunensis Raizada Ethanol Extract as an Antioxidant ]]>
<![CDATA[Mahyuni, Eka Lestari]]>;
<![CDATA[Harahap, Urip]]>
<![CDATA[ Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 1 (2024) ]]>
Publisher : <![CDATA[Sanata Dharma University ]]>
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DOI: 10.24071/jpsc.004492
<![CDATA[Antioxidants and their health implications are widely studied related to their benefits in reducing free radical exposure. Oxalis dehradunensisRaizada is a type of wild mountain clover containing flavonoids and polyphenols. These contents allow the leaves to be consumed in a more practical, effective, and efficient way by processing the extract into effervescent granules. This experimental study used samples of Oxalis dehradunensisRaizadaethanol extract formulated in the form of effervescent granules. The content included citric acid, tartrate acid, lactose and sodium bicarbonate. The antioxidant activity assays were conducted by DPPH methods including testing the total phenol and flavonoid contents for the extracts and forms of effervescent granules. The total phenol content analysis used the Folin-Ciocalteu method while the total flavonoid content used the colorimetry method. The results identified the extract as the hygroscopic extract which had increasing IC50 for upgraded content of the formula but looked wet and was not stable. The experiment for the formula of effervescent granules was fulfilled by adding povidone, aspartame and polyethylene glycol. It required angle of repose which was 200-400 with a flow time not exceeding 10 seconds. The tap density also fulfilled the requirements, with the smaller the granule tap density, the greater the compression volume. The extract has a good antioxidant with IC50 value which reached near moderate to high levels. Although the formula 4 of effervescent granules was the best, it did not have the best antioxidant activity. Based on the results from the antioxidant activity assays, the extract has good antioxidant activity but it decreased when made into effervescent granules. ]]>
