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PHYTOCHEMICAL SCREENING AND GC-MS ANALYSIS OF ETHANOLIC EXTRACT OF Chromolaena odorata LEAVES Aditya Candra; Tahara Dilla Santi; Ika Waraztuty; Syarifah Nora Andrianty; Andri; Said Aandy Saida
MEDALION Journal: Medical Research, Nursing, Health and Midwife Participation Vol. 7 No. 2 (2026): June
Publisher : PT. Radja Intercontinental Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Chromolaena odorata leaves are empirically known to act as anti-inflammatory and other pharmacological effects. In this study, ethanol extracts from Chromolaena odorata leaves were analyzed using phytochemical screening and gas chromatography-mass spectrometry (GC-MS) to identify phytochemical constituents. Phytochemical tests showed the presence of flavonoids, alkaloids, tannins, saponins, and phenolics. GC-MS analysis of ethanol extracts from Chromolaena odorata leaves detected the presence of seven phytochemical compounds, namely Ethyl (E)-4-(2-phenylethylamino)but-2-enoate; 2h-pyran 2-(7-heptadecynyloxy) tetrahydro; 3,7,11-Trimethyldodeca-2,6,10-trienyl acetate; Bicyclo(3.1.1)heptane, 2,6,6-trimethyl-,(1alpha,2beta,5alpha)-11,13-Dimethyl-12-tetradecen-1-yl acetate; (2E,7R,11R)-3,7,11,15-tetramethyl-2-hexadecen-1-ol, and 9,12,15-Octadecatrienoic acid. This study identified several constituents that are biologically active compounds through GC-MS. These phytocompounds have potential as herbal medicines due to pharmacological activities such as antioxidant, anti-inflammatory, antimicrobial, antibacterial, and anticancer.
Penilaian Risiko Menggunakan Metode Hazard Identification Risk Assesment and Determining Control (HIRADC) pada Petugas di IGD & IPLS RSUD Meuraxa Tahun 2025 Fikri Taufiqurrahman; Tahara Dilla Santi; Dedi Andria
INSOLOGI: Jurnal Sains dan Teknologi Vol. 5 No. 2 (2026): April 2026
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v5i2.7653

Abstract

The hospital work environment, particularly the Emergency Department (ER) and the Sanitation Waste Management Department (IPLS), has various potential hazards that can threaten the safety of staff. This study aims to identify potential hazards, assess risk levels, and determine occupational risk controls using the HIRADC method at Meuraxa Regional General Hospital. This quantitative study with a descriptive observational approach used a facility observation checklist and semi-structured interviews with staff. Data collection was conducted from June 1–16, 2025, through observation, documentation, and interviews. Risk analysis was based on likelihood and severity, then classified into low, medium, and high risks. The results showed a higher risk of infectious diseases among ER staff (57.1%) compared to ER staff (28.6%). In the ER, moderate–high risks were found in unfastened oxygen cylinders, dusty defibrillators, dirty suction pumps and HFNCs, and portable X-rays without radiation protection. Dominant risks included needlesticks, infection exposure, ampule injuries, limited PPE, noise, aggressive patients, and confined spaces. At the IPLS, high risks are found in the electrical panels and water pumps, and moderate risks are found in the filters and storage areas. The HIRADC method is considered effective and needs to be supported by strengthened controls, OHS training, and strict SOPs.
Faktor Hubungan Tingkat Kekambuhan Pada Penderita Asma Di Wilayah Kerja Puskesmas Banda Raya Kota Banda Aceh Tahun 2023 Vira Magfirah Maisuri; Tahara Dilla Santi; Riza Septiani
Jurnal Penelitian Inovatif Vol 6 No 2 (2026): JUPIN Mei 2026
Publisher : CV Firmos

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54082/jupin.1467

Abstract

Asma merupakan penyakit kronis saluran pernafasan yang memicu batuk serta sesak nafas. Serangan asma timbul karena adanya faktor predisposisi dan paparan terhadap faktor pencetus. Penelitian bertujuan untuk mengetahui faktor yang berhubungan dengan tingkat kekambuhan asma di wilayah kerja Puskesmas Banda Raya Kota Banda Aceh. Penelitian bersifat kuantitatif analitik dengan desain cross sectional. Populasi dalam penelitian adalah pasien asma di Puskesmas Banda Raya yang berjumlah 52 jiwa. Sampel ditentukan dengan menggunakan teknik total sampling berjumlah 52 pasien yang tercatat mengalami asma dan melakukan pengobatan di Puskesmas. Analisis data yang digunakan adalah analisis univariat dan bivariat dengan uji chi-square yang menggunakan aplikasi SPSS. Hasil analisis univariat menunjukkan penderita asma terkontrol penuh 15,3%, terkontrol sebagian 30,77% dan yang tidak terkontrol 53,58%. Responden yang terpapar asap rokok 59,62%, Aktivitas Fisik sedang 90,38%, stres 71,15%, terpapar polusi 59,62% dan cuaca 98,08 resiko. Analisis bivariat menunjukkan ada hubungan antara asap rokok (p value =0,024), polusi (p value =0,024), aktivitas fisik (p value =0,275), stres (p value= 0,035) dengan tingkat kekambuhan asma di wilayah kerja Puskesmas Banda Raya Kota Banda Aceh. Diharapkan petugas kesehatan dapat melakukan edukasi kesehatan kepada pasien  agar mereka mengetahui faktor yang dapat memicu kekambuhan asma. Dengan pemahaman yang baik, pasien lebih rutin memeriksa diri, sehingga dapat mengurangi kasus kekambuhan asma di wilayah kerja Puskemas Banda Raya Kota Banda Aceh.
Formulation and optimization of Syzygium polyanthum leaf patch as a potential diabetic wound healing using Box-Behnken design Tahara Dilla Santi; Aryandi Darwis; Nasyata Safira
Media Penelitian dan Pengembangan Kesehatan Vol. 36 No. 2 (2026): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v36i2.4223

Abstract

ABSTRACT Background: Pathological changes in the body due to diabetes mellitus interfere with the wound healing process. Syzygium polyanthum leaves contain abundant phenolic compounds and act as anti-inflammatory, antioxidant and antibacterial enabling them to play a crucial role in the healing of diabetic wounds. Patches are an effective drug delivery method because they are easy to control the release, easy to obtain and affordable for the general public. Objective: The purpose of study was to identify the best formulation and optimization of bay leaf patches as a potential for healing diabetic wounds. Methods: Syzygium polyanthum leaves were extracted using maceration techniques and compound identification using Gas Chromatography-Mass Spectrometry (GC-MS). The procedure for figuring out the ideal patch involved utilizing the Box-Behnken Design technique, which looked at three different things: bay leaf extract (BLE), polyvinyl pyrrolidone (PVP), and ethyl cellulose. The observed responses included air content (%), weight, and thickness. Results: The results of the GC-MS test obtained Tetradecanoic acid, 12-methyl - methyl ester, Estra-1,3,5 (10)-trien-17 ß-ol, n-Hexadecanoic acid, 9,10-Secocholesta-5,7,10(19) -triene-3,24, 25 triol, (3ß, 5Z,7E), Stigmasta-3,5-diene, Ergosta-5,22-dien-3-ol, acetate, (3ß,22E) . ANOVA analysis showed that the quadratic model was appropriate because it produced high R² values ​​and low PRESS values ​​for weight and thickness responses (p-value <0.0500). Conclusion: The optimal formulation for bay leaf patch was 117.271 mg of BLE, 396.274 mg of ethyl cellulose, and 227.237 mg of PVP. This formulation achieved the desired response of 2.683% water content, 0.462 mg weight, and 0.369 mm thickness.
Faktor-Faktor yang Mempengaruhi Kejadian Komplikasi Diabetes Melitus di Wilayah Kerja Puskesmas Ingin Jaya Kecamatan Ingin Jaya Kabupaten Aceh Besar Ema Fadila Liunsanda; Tahara Dilla Santi; Dharina Baharuddin
INSOLOGI: Jurnal Sains dan Teknologi Vol. 5 No. 3 (2026): Juni 2026
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v5i3.8183

Abstract

Diabetes mellitus is a chronic metabolic disease characterized by elevated blood glucose levels due to impaired insulin secretion or function. If left uncontrolled, this disease can lead to serious complications affecting vital organs. According to the 2023 Indonesian Diabetes Association (SKI), the prevalence of diabetes in Indonesia reached 1.7%, and in Aceh it was 1.6%. Aceh Besar Regency recorded 8,517 cases, with Ingin Jaya District ranking second with 785 cases. Widespread unhealthy behaviors increase the risk of complications. This study aims to identify factors influencing the incidence of diabetes mellitus complications, including income, family support, knowledge, attitudes, diet, physical activity, foot care, medication adherence, and blood sugar monitoring. The study used a quantitative approach with a case-control design. The population consisted of 39 individuals, with a total sampling technique, resulting in 78 respondents. The study was conducted from July 6–14, 2025, using a standardized questionnaire. Data analysis was conducted using univariate, bivariate, and multivariate methods using the chi-square test and binary logistic regression. The study results showed that physical activity (p=0.003; OR=10.360) and blood sugar monitoring (p=0.036; OR=9.806) influenced diabetes complications. Multivariate analysis confirmed these findings, while other variables showed no significant effect. It is recommended that health agencies utilize these results to strengthen health promotion, routine screening, risk factor monitoring, and improve public education on diabetes mellitus prevention and management.
Case Control Study Faktor Risiko Kejadian Hipertensi pada Pegawai Kantor Gubernur Aceh Kota Banda Aceh Tahun 2022: Case Control Study Risk Factors of Hypertension in Aceh Governor Office Employees in Banda Aceh City in 2022 Putri Riza Yana; Tahara Dilla Santi; Farrah Fahdhienie; Dharina Baharuddin
Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Vol. 6 No. 9 (2023)
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/mppki.v6i9.3605

Abstract

Latar belakang: Hipertensi merupakan salah satu Penyakit Tidak Menular (PTM) yang menjadi masalah kesehatan yang paling serius yang dapat memicu berbagai penyakit mematikan seperti jantung dan stroke. Hipertensi dapat terjadi akibat beberapa faktor risiko seperti kebiasan hidup yang kurang baik, pola diet yang kurang baik atau kualitas tidur yang kurang baik. Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan aktivitas fisik, merokok, lingkar perut dan BMI (Body Mass Indeks) dengan kejadian hipertensi. Metode: Penelitian ini menggunakan metode Kuantitatif dengan desain Case Control, populasi adalah 200 pegawai dengan pengambilan sampel menggunakan non random sampling yang berupa purposive sampling yaitu dari data survei milik peneliti sebanyak 90 pegawai diantaranya 30 kasus dan 60 kontrol. Hasil: Hasil penelitian menunjukkan bahwa hasil univariat aktivitas fisik sedang (46,67%), lingkar perut normal (100%), tidak merokok (86,67%), memiliki BMI normal (100%). Hasil bivariat hubungan antara aktivitas fisik (p value 0,001 dan OR 0,01-0,04), lingkar perut (p value 0,001 dan OR 0,07-0,30), merokok (p value 0,001 dan OR 8,5), BMI (p value 0.001 dan OR 1) dengan kejadian hipertensi. Kesimpulan: Sebaiknya Kepala Dinas Kesehatan Kota Banda Aceh untuk melakukan promosi kesehatan pada pegawai di kantor seperti penyuluhan, selain itu kepala bidang isra dapat mencanangkan program baru seperti senam sehat dan memberikan edukasi terkait pola makan.
Factors Associated with Blood Sugar Control Behavior on Patients with Diabetes Mellitus in Blang Kuta Community Health Center Area, Pidie Jaya District in 2023 Mutiara; Tahara Dilla Santi; Wardiati
Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Vol. 7 No. 7 (2024)
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/mppki.v7i7.5283

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Introduction: Diabetes mellitus has become one of the increasingly alarming global health challenges. As a chronic disease, diabetes results in various detrimental consequences, including high mortality rates and significant healthcare costs. Objective: This research aims to determine the factors associated with blood sugar control behavior among diabetes mellitus patients in the Blang Kuta Community Health Center's service area. Method: This study is a quantitative research with a cross-sectional approach. The population in this study consists of all DM patients in 4 villages in the Blang Kuta Community Health Center's service area, totaling 252 individuals. Sampling was conducted using proportional random sampling techniques, involving 72 DM patients. Data collection was performed through interviews using questionnaires and analyzed through univariate, bivariate analysis using chi-square test, and multivariate analysis using logistic regression test using the SPSS program. Result: The univariate analysis results revealed that the majority of respondents exhibited poor behavior (54.2%). Bivariate analysis results indicated a significant relationship between knowledge (p-value 0.000), level of education (p-value 0.002), gender (p-value 0.005), and self-efficacy (p-value 0.000) with blood sugar control behavior. However, variables such as family history (p-value 0.471) and duration of diabetes mellitus (p-value 0.277) did not show a significant relationship. Multivariate analysis results indicated that knowledge (p-value = 0.035, OR = 5.114) and self-efficacy (p-value = 0.000, OR = 13.278) are important determinants of blood sugar control among patients with diabetes mellitus. Conclusion: There is a significant relationship between knowledge, education, gender, and self-efficacy with blood sugar control behavior. However, variables such as family history of diabetes mellitus and duration of diabetes mellitus do not show a significant relationship. Nonetheless, factors strongly associated with blood sugar control behavior in diabetic patients are knowledge and self-efficacy.
SOCIALIZATION AND GUIDANCE IN THE MAKING OF HERBAL SAUNAS IN ALUE DEAH TEUNGOH VILLAGE IN 2025 Tahara Dilla Santi; Aditya Candra; Naimah; Ika Waraztuty; Andri; Said Aandy Saida; Ns. Eka Oktarina Riani
International Review of Practical Innovation, Technology and Green Energy (IRPITAGE) Vol. 5 No. 3 (2025): November 2025 - February 2026
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.19464730

Abstract

The International Labor Organization (ILO) reports that 2 million people die in the workplace, one of the causes being overexertion. Herbal saunas are decoctions of plants with medicinal properties, including anti-fatigue. Warm steam applied to the skin helps dilate blood vessels, improving circulation. The purpose of this activity was to provide knowledge about various medicinal plants that can be used as herbal saunas and to provide community members with skills in making herbal saunas. The PKM method involved participation through outreach and mentoring women in preparing herbal saunas. The activity took place on July 27, 2025, in Alue Deah Teungoh Village, with 15 women participating in the Family Welfare Movement (PKK). The activity began with a pre-test and then a herbal sauna booklet. The results of this activity were an increase in the knowledge and skills of the PKK women, demonstrated by the resulting product, a dried herbal sauna packaged in a standing pouch. Participants were very enthusiastic about the training. The activity concluded with the use of herbal saunas, which were boiled in a steamer and the steam flowed into a portable sauna tent. Participants took turns using the sauna, which had been filled with the herbal sauna decoction.
DEVELOPMENT OF ADHA SUPPLEMENT INNOVATION (MORINGA LEAF ANTI-FATIGUE NATURAL HERBAL) AS A SUPERIOR PRODUCT OF NUSA TOURISM VILLAGE Aditya Candra; Tahara Dilla Santi; Muhammad Faisal
International Review of Practical Innovation, Technology and Green Energy (IRPITAGE) Vol. 5 No. 3 (2025): November 2025 - February 2026
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.19480150

Abstract

The Community Partnership Empowerment (PKM) program involves Family Welfare Movement (PKK) group partners. Preparation for the program began in June 2025, beginning with a visit by the implementation team to Gampong Nusa to conduct a survey to assess community conditions. During the subsequent visit, the team submitted a PKM implementation permit from LPPM UNAYA and briefly presented the PKM program. The team explained the stages of the program, the implementation schedule, and other details. Counseling and training were held on September 20, 2025, followed by mentoring in the production of ADHA products, including moringa tea, moringa powder, moringa sachets, and moringa capsules. Following the mentoring, the best and fastest group in producing ADHA products was selected. Subsequently, on September 21, 2025, the community service team planted 250 moringa cuttings in several locations in Gampong Nusa..
FAKTOR YANG BERHUBUNGAN DENGAN TINDAKAN PERAWAT DALAM PEMILAHAN LIMBAH MEDIS RSUD KOTA SABANG Jihan Fadhillah; Tahara Dilla Santi
Jurnal Ilmu Kesehatan Insan Sehat Vol. 13 No. 2 (2025): Jurnal Ilmu Kesehatan Insan Sehat
Publisher : STIKES Intan Martapura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54004/jikis.v13i2.429

Abstract

Pendahuluan: Pengelolaan limbah medis rumah sakit sangat penting karena  memiliki berbagai risiko terhadap kesehatan bagi siapa saja, termasuk karyawan rumah sakit, pasien dan masyarakat. Tujuan: Penelitian ini bertujuan untuk mengetahui faktor yang berhubungan dengan tindakan perawat dalam pemilahan limbah medis di RSUD Kota Sabang. Metode: Desain penelitian deskriptif analitik dengan pendekatan cross sectional. Populasi adalah semua perawat di RSUD Kota Sabang tahun 2022 sebanyak 158 perawat. Pengambilan sampel menggunakan propotional sampling sebanyak 61 sampel. Pengumpulan data menggunakan kuesioner melalui wawancara. Analisis data menggunakan uji Chi-Square. Hasil : Hasil menunjukkan bahwa 60,7% pemilihan limbah medis kurang baik, 50,8% berpengetahuan baik, 57,4% bersikap positif, 54,1% masa kerja lama dan 52,2% responden dengan pelatihan. Hasil analisis bivariat diperoleh bahwa ada hubungan pengetahuan (ρ value = 0,002), sikap (ρ value = 0,006), masa kerja (ρ value = 0,008) dan pelatihan (ρ value = 0,021) dengan tindakan perawat dalam pemilihan limbah medis di RSUD Kota Sabang. Kesimpulan: Semua variabel memiliki hubungan dengan tindakan perawat dalam pemilihan limbah medis di RSUD Kota Sabang tahun 2022. Saran: Diharapkan pimpinan rumah sakit untuk memperketat peraturan mengenai tindakan perawat dalam pemilihan limbah medis di RSUD Kota Sabang dan kepada perawat di RSUD Kota Sabang untuk memilah sampah medis.
Co-Authors Aditya Candra Aditya Candra Aditya Candra Aditya Candra Aditya Candra Aditya Candra Aditya Candra Aditya Candra, Aditya Afnita, Ana Agustina Al-Fattah, Muhammad Dea Alfais, M. Razi Alma Aletta Amin, Fauzi Ali Andri Andri Andria, Dedi Anwar Arbi Anwar Arbi Arbi, Anwar Arifin, Vera Nazhira Ariscasari, Putri Arlianti, Nopa Aryandi Darwis As Sadiyyah, Halimah Asarah Kamilah Kamilah Asnawi Abdullah Aulia, Putra Rizki Ayu Vinezia Situmeang Azwar, Eddy Basri Aramico Basri Aramico Cahyani, Amelia Regita Darmawan, Aldi Dedi Andria Devi Satul Hajar Devy Surya Mawaddah Dharina Baharuddin Dharina Baharuddin Ema Fadila Liunsanda Era Fazira Fahmi Ichwansyah Farrah Fahdhienie Fauzi Ali Amin Febyolla Presilawati Fikri Taufiqurrahman Hanifah Hasnur Hasnur, Hanifah Heni Pujiastuti Hermansyah Hermansyah Hidayani, Halimah Ika Waraztuty Ika Waraztuty Jabari, Jabari Jazila, Ulfatul Jihan Fadhillah Kamal, Muhammad Hasyim kausar, aidil Kausar, Muhammad Anis AL Khaira, Uswatul Laweung, Ibrahim Lestari, Citra Yuli Linggo, Aris Luthfi Nanda Perdana M. Biomed M. Biomed M. Yani Mahrani, Ayu Maidar, Maidar Maidayani Maidayani Manovri Yeni Mashuri, Evan Maulidya, Rizki Meutia Zahara MONA HILOKA MAQFIRAH Muetia Nandia Putri Muhammad Faisal Muhammad Muhammad Muhammad Ziqraullah muid, abd Munandar, Arief Munawarah, Zakiya Mutiara Nabil Shidqi Naimah Nasyata Safira Nauval, Muhammad Dharma Na’imah Nizam, Fahrul Nourah Nazifa Ns. Eka Oktarina Riani Parisi, Tgk Adil Putri Riza Yana Putri, Hasdiani Radhiah Zakaria Radhiah Zakaria Rahmi, Ananda Fathur Raihani, Fitri Ramadhana, Desfrianda Ramadhaniah Ramadhaniah Riza Septiani Riza Septiani Rovita Marianda Z Marianda Z Said Aandy Saida Said Aandy Saida Salbila Salbila Sanju, Bunga Salsa Santi, Hafnidar Sari, Fera Indah Savira Fitri Savira Usrati Septiani, Riza Sonia Bella Sanjaya Surna Lastri Sutri Helfianti Syarifah Fazhila Azzahra Syarifah Nora Andrianty Syarifah Nora Andriaty Syarifuddin Syarifuddin Syawaluddin Syawaluddin, Syawaluddin Tri Mulyani Ullya, Jaida Usrati, Savira Utari, Nadia Vera Nazhira Arifin Vira Magfirah Maisuri Wardiati, Wardiati Winda Putri Diah Restya, Winda Putri Zaafira, Zaafira Zahara, Amelia Zakaria, Radhiah Zulkifli Zulkifli Zuriati, Nura