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All Journal Jurnal Sain Veteriner Jurnal Riset Kesehatan Jurnal Teknologi Laboratorium Jurnal SOLMA Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Analis Medika Biosains (JAMBS) Medical Laboratory Analysis and Sciences Journal Lumbung Farmasi : Jurnal Ilmu Kefarmasian Medicra (Journal of Medical Laboratory Science/Technology) Jurnal Mitra Kesehatan Journal of Indonesian Medical Laboratory and Science (JoIMedLabS) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Pharmaqueous Jurnal Pengabdian Pancasila (JPP) Jurnal Laboratorium Khatulistiwa Jurnal Pengabdian Masyarakat (Jupemas) Jurnal Pengabdian Masyarakat Mandira Cendikia (JPKM-MC) Jurnal Bioteknologi & Biosains Indonesia (JBBI) Indonesian Journal of Innovation Multidisipliner Research Jurnal Ilmiah Nusantara Jurnal Bioteknologi & Biosains Indonesia
Imam Agus Faizal
Program Studi Sarjana Terapan Teknologi Laboratorium Medis, Fakultas Farmasi Sains Dan Teknologi, Universitas Al Irsyad Cilacap, Jalan Cerme No.24, Wanasari, Sidanegara, Kec. Cilacap Tengah, Kabupaten Cilacap, Jawa Tengah, Indonesia. 53223
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Herd immunity and COVID-19 in Indonesia Faizal, Imam Agus; Ariska Nugrahani, Nur
Jurnal Teknologi Laboratorium Vol 9 No 1 (2020): 2020 (1): Special Edition "COVID-19"
Publisher : POLTEKKES KEMENKES YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2392.808 KB) | DOI: 10.29238/teknolabjournal.v9i1.219

Abstract

Herd immunity or herd effect is a phenomenon that occurs in groups of people who are resistant to disease. The purpose of conducting this research is to predict the number of cumulative cases of COVID-19 in Indonesia. Covid-19 cases in Indonesia on April 6, 2020, were 2235 cases spread in 34 Provinces. As many as 2491 cases in Indonesia, there were 192 patients recovered (including those treated, so they have natural antibodies in the end) while the total who died was 209 people. It is assumed that around 13% of the total cases have natural antibodies. This is also the case with SARS-CoV-2 and may explain why some individuals (perhaps those most recently able to recover from seasonal coronavirus infections) have asymptomatic infections. Finally, the theoretical concept of increasing herd immunity in pandemic and epidemic cases in Indonesia which aims to control COVID-19 still needs to be reviewed because it is seen from the mortality data that CFR COVID-19 is predicted to be around 8.39% of the population in Indonesia where the risk of death still available. The best alternative is to do a healthy lifestyle, social distancing, and waiting for the vaccine to be found.
Model Granuloma Tuberculosis In Vitro Sebagai Deteksi Awal Tingkat Keparahan Penyakit Tuberkulosis Imam Agus Faizal
Jurnal Analis Medika Biosains (JAMBS) Vol 7, No 2 (2020): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v7i2.197

Abstract

Mycobacterium tuberculosis is a cause of Tuberculosis in humans causing death and one of the infectious agents in humans in the world. It is estimated that there are 8.7 million new cases, 1.4 million deaths, and around 2 billion latent infections caused by Mtb. According to WHO in 2014, an estimated 9.6 million people transmitted active TB disease, of which 1.5 million died and the burden of TB was heterogeneously distributed in various regions of the world. This type of research is a pure experiment with in vitro methods of making granuloma TB models that are similar to humans. The purpose of this study is to detect early the severity of tuberculosis. The results of the study that on the 1st day granuloma has not formed because the structure of granuloma has not formed yet because blood immune cells in PBMC media containing lymphocyte and monocyte cells are not yet responding to Mtb infection. On day 2 the granuloma structure surrounding the Mtb bacteria has begun to form forming an aggregation. Day 3, many other cell types also occupy granulomas, such as neutrophils, dendritic cells, B and T cells, natural killer cells, fibroblasts and cells that secrete extracellular matrix components. Day 4 granulomas undergo granulation and the structure of the granuloma breaks and maximum damage aggregation occurs on the 5th day. when the host's immune system weakens, it is known that active Mtb residents prevent active Tb. Experimental evidence has revealed that the TNF-α factor plays a major role in host defense against Mtb in both active and chronic infection phases. The study of granuloma tuberculosis from the above explanation can be concluded that the severity of tuberculosis can be detected early with the in vitro observation method of granuloma in order to provide appropriate drug therapy even this research can be used as an initial stage of perfecting the vaccine in tuberculosis infection.
HOUSE ENVIRONMENTS AS RISK FACTORS OF TUBERCULOSIS IN CILACAP DISTRICT Imam Agus Faizal; Ira Pangesti; Denih Agus Setia P
Jurnal Riset Kesehatan Vol 10, No 1 (2021): MAY 2021
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (180.717 KB) | DOI: 10.31983/jrk.v10i1.6694

Abstract

Tuberculosis (TB) is a disease caused by the bacterium Mycobacterium tuberculosis which is still a major global health problem in the world and causes morbidity rates in millions of people each year. new cases of positive BTA in Central Java in 2017 amounted to 60.91 per 100,000 population. Meanwhile, based on the profile of the Cilacap District Health Office in 2018, the number of TB sufferers reached 5271 cases, around 1089 TB cases that have not been found and reported, while 34 of them died. The purpose of this study was to analyze the risk factors for tuberculosis incidence in Cilacap Regency. The purpose of this study was to analyze House Environments As Risk Factors Of Tuberculosis In Cilacap District. This type of research is an observational analytic quantitative approach with a research design that is using case control and cross-sectional which was conducted from May 2020 to June 2020 in the work area of the RSUD Cilacap Paru Center. The Respondents this research is the person who lived in the work area of the public health center using total sampling technique so that it is obtained 30 respondents. This study concludes significant effect on floor types, natural ventilation and housing density. Meanwhile, the respondent's characteristic factors such as smoking habit, phlegm discharge habit and coughing and sneezing influenced the incidence of tuberculosis.
The detection of Mycobacterium tuberculosis using in vitro granuloma tuberculosis model intracelluler specimens Imam Agus Faizal; Jusak Nugraha; Agung Dwi Wahyu Widodo
Medical Laboratory Analysis and Sciences Journal Vol 2 No 1 (2020): May 2020
Publisher : Department of D3 Medical Technology Laboratory STIKes Hutama Abdi Husada Tulungagung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35584/melysa.v2i1.46

Abstract

The Granulomas are a group of innate and adaptive immune cells that are highly organized, and during tuberculosis infection caused by the bacterium Mycobacterium tuberculosis. Estimated as many as 1.6 million cases of death in 2017 according to World Health Organization. Tuberculosis ranks in the top 10 causes of death worldwide and it is predicted that more than 1.7 billion people (around 25 percent of the world's population) are estimated to be infected by Mycobacterium tuberculosis. The purpose of this study was to confirm the Mtb by examining a new method by modifying Ziehl-Neelsen stain using an intracellular specimens for tuberculous granuloma in vitro. This study used the isolate of the bacterium Mycobacterium tuberculosis H37Rv obtained from the Microbiology Laboratory of the Institute of Tropical Disease Universitas Airlangga, Surabayaa, using Peripheral Blood Mononuclear Cells to make model granuloma tuberculosis. The result is Ziehl-Neelsen staining was modified, it was found that the Mycobacterium tuberculosis H37Rv as detection of bacterial confirmation is said to be successful.
In silico studi of Orthosiphon aristatus as antioxidant Dian Novita; Imam Agus Faizal
Medical Laboratory Analysis and Sciences Journal Vol 2 No 2 (2020): November 2020
Publisher : Department of D3 Medical Technology Laboratory STIKes Hutama Abdi Husada Tulungagung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35584/melysa.v2i2.59

Abstract

Orthosiphon aristatus (O. aristatus) is a herbal plant that has antioxidant activity. This study was conducted in a preliminary study of the potential active compound O. aristatus with in silico software pyrex autodock vina method, and visualization using biovia discovery studio. Results from the study in silico showed that O.aristatus extract has potential as an antioxidant compound. Result value of binding affinity with SOD receptor proteins having more negative values compared to control compounds. The interaction of O.aristatus extract is quite potential as an antioxidant, through hydrogen bonding that is equal to control, namely vitamin E
FORMULASI DAN EVALUASI NANOEMULSI MINYAK IKAN SIDAT MENGGUNAKAN METODE SONIKASI Adilla Putri Az-Zahra; Faulia wijayanti; Lailiya Ramadhanti; Imam Agus Faizal
Pharmaqueous : Jurnal Ilmiah Kefarmasian Vol. 4 No. 2 (2022): Volume 4, Nomor 2, November 2022
Publisher : Prodi S1 Farmasi, Universitas Al Irsyad Al Islamiyyah Cilacap

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36760/jp.v4i2.448

Abstract

Nanoemulsi merupakan salah satu bentuk sediaan yang stabil, transparan dan memiliki ukuran droplet yang sangat kecil biasanya di kisaran 20-200 nm. Nanoemulsi dibuat dengan mencampur fase minyak dan fase air dengan bantuan surfaktan dan kosurfaktan untuk menurunkan tegangan antarmuka. bermanfaat bagi kesehatan. Omega-3 merupakan salah satu asam lemak tak jenuh yang esensial bagi tubuh dan dibutuhkan terutama bagi penderita kolesterol tinggi, EPA dan DHA merupakan jenis omega-3 yang paling dominan pada minyak ika. Bahwa Ikan sidat dari hasil budidaya yang berasal dari daerah Cilacap (Indonesia) dengan berat rata-rata 300 g/ekor mengandung protein 17,51 %, lemak 17,72 %, kadar air 62,36 % dan kadarabu 1,33 %.
Perbandingan Metode Maserasi Dan Soxhletasi Ekstrak Daun Sirih Merah (Piper crocatum Ruiz & Pav) Terhadap Efektivitas Bakteri Staphylococcus epidermidis Imam Agus Faizal; Alifah Alifah Alifah
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 4, No 1 (2023): Januari
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v4i1.10728

Abstract

Sirih merah (Piper crocatum Ruiz & Pav) secara empiris dalam pemanfaatan sebagai pengobatan dengan proses direbus dalam air. Sirih merah (Piper crocatum Ruiz & Pav) memiliki kandungan metabolit, alkaloid, flavonoid, tanin dan minyak atsiri dengan aktifitas sebagai antioksidan dan antibakteri. Tujuan dari penelitian ini adalah pengetahuan metode yang paling efektif untuk ekstraksi daun sirih merah (Piper crocatum Ruiz & Paiv) terhadap antibakteri Staphylococcus epidermidis dan mengetahui aktivitas antibakteri daun sirih merah (Piper corcatum Ruiz & Pav) menggunakan metode maserasi dan soxhletasi. Ektraksi dilakukan dengan dua metode yaitu maserasi dan soxhletasi menggunakan pelarut etanol 96% kemudian dilakukan uji fitokimia yang menghasilkan bahwa esktrak daun sirih merah mengandung saponin, alkaloid, flavonoid dan tanin. Uji antibakteri Staphylococcus epidermidis menggunakan metode difusi sumuran dengan konsentrasi 30%, 50% dan 70% untuk kedua metode yaitu maserasi dan soxhletasi dihasilkan zona hambat yang masuk dalam kategori sensitif. Hasil penelitian dapat disimpulkan bahwa metode yang paling efektif dalam ekstraksi senyawa antibakteri daun sirih merah (Piper crocatum Ruiz & Pav) yaitu dengan menggunakan metode soxhletasi. Aktivitas antibakteri yang paling efektif dari daun sirih merah (Piper crocatum Ruiz & Pav) yaitu pada metode soxhletasi konsentrasi 70% dengan kategori daya hambat sangat kuat.
ANALYSIS OF FASTING ON BLOOD TESTS Imam Agus Faizal; Frisca Dewi Yunadi; Sodikin Sodikin; Ayuningtyas Ayuningtyas
Jurnal Riset Kesehatan Vol 12, No 1 (2023): MAY 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jrk.v12i1.9495

Abstract

As a procedure to obtain information with bodily fluid samples, a laboratory test is complementary to a diagnostic assessment. One parameter of laboratory tests is hematology, for which a blood profile is used to evaluate clinical conditions and provide diagnostic information about hematological abnormalities, prognosis, and response treatment. Nowadays, accessibility to laboratory tests has been made easier with medical checkups integrated into the Occupational Health and Safety program, which a company is obliged to have to check on its employees’ health status. Our study analyzed the results of fasting blood tests on the employees of The College of Health Sciences of Al-Irsyad Al-Islamiyyah Cilacap. This College is known for the practice of Islamic and religious values, including fasting, among its employees. Taking the employees as a population and samples, the research included variables of levels of erythrocytes, leukocytes, hemoglobin, and hematocrit in the descriptive analysis method. We gained eleven respondents, 8 males, and 3 females, and used a cluster sampling method with appropriate criteria. The data of obtained samples were analyzed and processed based on the interpretation of the results. The results of routine blood examinations on fasting showed 90.90% normal hemoglobin levels and 72.70% normal hematocrit levels. Conclusively, our results of the blood profile examination on hemoglobin and hematocrit in fasting people showed that fasting is metabolically healthy and produces no indication of anemia.
Hepatotoxic Test Of Burdock Roots (Arctium Lappa L) On Histopathology Hepar Of Male White Rats (Rattus Norvegicus Wigati, Atika Nur; Faizal, Imam Agus; Puspodewi, Dini
Jurnal Riset Kesehatan Vol 13, No 2 (2024): NOVEMBER 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jrk.v13i2.11903

Abstract

Burdock (Arctium lappa L) is a homologous medical plant that is considered having with many advantages as a traditional medicine. Burdock root contains several substances such as inulin, essential oils, tannins, quercetin,iron, and arctigenin. This study was conducted to determine investigates effect of burdock root extract on the hepar histopathology of male white rats. This study used an experimental method with 20 rats and was divided into 4 groups. The positive control group was given gentamicin induction intramuscularly. The negative control group was given distilled water. The 150 mg/kgBW dose group and the 450 mg/kgBW dose group were given burdock root extract with treatment for 14 days and surgery was performed oin the 15th day to take hepatic organs to make histopathology preparations. The results of the this study were are interpreted by scoring and tabulated, the analysis was is done carried out descriptively with the results, in positive control group found mild damage, the negative group found no damage, in the extract dose group 150mg/kgBW found necrosis, bleeding and vacuolization, and in the extract dose group 450mg/kgBW found degeneration, necrosis, bleeding and vacuolization. The conclusion of this study is the hepatoprotective potential of burdock root extract (Arctium lappa L.) and its related effects on liver tissue in an experimental model. On the other hand, parasitic worms Taenia taeniaeformis were found in the liver which interfered with the interpretation of the results.
Meningkatkan Status Gizi Balita Melalui Praktik Pengolahan Makanan Pendamping ASI (MP-ASI) Dalam Upaya Pencegahan Stunting Di Kelurahan Sidanegara Frisca Dewi Yunadi; Imam Agus Faizal
Jurnal Pengabdian Masyarakat Mandira Cendikia Vol. 4 No. 2 (2025)
Publisher : YAYASAN PENDIDIKAN MANDIRA CENDIKIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70570/jpkmmc.v4i2.1639

Abstract

Praktek Pemberian makanan pendamping ASI masih menjadi permasalahan, terutama pada balita gizi kurang. Data Kelurahan Sidanegara Wilayah Puskesmas Cilacap Tengah I, terdapat 198 balita terdeteksi stunting sampai pada bulan Juli 2019. Pada tahun 2022 terjadi kenaikan angka kejadian stunting menjadi 220 balita. Stunting merupakan kondisi kekurangan gizi kronis yang berdampak secara tidak langsung terhadap kualitas Sumber Daya Manusia (SDM). Stunting adalah kondisi dimana balita memiliki panjang atau tinggi badan yang kurang jika dibandingkan dengan umur. Pengabdian kepada masyarakat adalah untuk meningkatkan pengetahuan dan keterampilan ibu yang memiliki balita gizi kurang dalam pengolahan makanan pendamping ASI buatan sendiri.. Pengetahuan dan ketrampilan yang diperoleh dari kegiatan ini diharapkan dapat bermanfaat untuk menumbuhkan kesadaran ibu-ibu mengenai dampak dari stunting terhadap tumbuh kembang anak dan menambah ketrampilan ibu balita dalam pengolahan makanan pendamping ASI (MP-ASI) buatan sendiri. Hsil pengabdian ada peningkatan pada ibu balita dan ketrampina dalam mengolah makanan MP-ASI
Co-Authors Adilla Putri Az-Zahra Afrilla, Rananda Agung Dwi Wahyu Widodo Ajeng Puspo Aji Alifah Alifah Alifah Arelliza, Fatma Sheilla Ayuningtyas Ayuningtyas BUDIYANTO Dede Yusuf, Dede Denih Agus Setia Permana Dian Novita Dini Puspodewi Elfred Rinaldo Kasimo, Elfred Rinaldo Farabi, Meka Faizal Fariza Yulia Kartika Sari Faulia wijayanti Fauziah, Rahma Shifa Frisca Dewi Yunadi Frisca Dewi Yunadi Haryanti, Anik Hayati, Defi Nurul Ihsan, Kharisul Ira Pangesti Jusak Nugraha Kusumawati, Dhiah Dwi Lailiya Ramadhanti Ma’rifah, Solihatul Mika Tri Kumala Swandari Mika Tri Kumala Swandari, Mika Tri Kumala Ningrum, DM Ningrum, Windi Nisa, Dwi Faizatun Nizam, Muhammad Farid Khoirun Nugrahaeni, Dian Rahma Nugroho, Yusuf Eko Nur Ariska Nugrahani Octaviany, Frinsisca Pangesti, Ira Permana, Denih agus Setia Priyanto, Anggih Purwati, Rina Putri Maretyara Saptyani Ramadhan, Fahri Riviani Riviani, Riviani Saputri, Ratna Dwi savitri, Lisa Sa’adah, Arina Lis Sodikin Sodikin Susanti Susanti Utami, Tri Fitri Yana Wigati, Atika Nur Wulandari, Mei Yayuk Mundriyastutik Yulianto, Asep Nurrahman yunadi, frisca dewi Yunadi, Frisca Dwi