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STATUS HOMOCYSTEINE DAN ASAM FOLAT PADA IBU HAMIL MEREKA Dewi Permaesih; Yuniar Rosmalina; Reviana Christijani; Muhilal Muhilal
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) JILID 24 (2001)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v0i0.1507.

Abstract

HOMOCYSTEINE AND FOLIC ACID STATUS OF ANEMIC PREGNANT WOMEN.Background: Folic acid deficiency among pregnant women in Indonesia is quite prevalent. It is believed to cause the anemia and the risk of infant neutral tube defect. Folic acid plays a certain role in homocysteine convertion into methionine. Serum homocysteine will increase with the decrease folic acid.Objective: To obtain folic acid consumption, homocysteine and folic acid status in pregnant women suffering from anemia using recent method of determination, and relationship of the three variables.Methodology: Pregnant women in the study area were screened by their Hb values under 11 g/dL. Thirty anemic pregnant women consumption was obtained by used 2x24 hours recall method. Folic acid was analysed by Ion Capture Method and homocysteine was analysed by Fluoresence Polarization Immuno assay.Results: Folic acid consumption was 61 ± 50 µg/mL with a range of 3.5 to 15.1 µg/mL. Normal value of serum folic acid was 3.1 to 12.4 µg/mL. Therefore, the value folic acid of pregnant women in this study was still in the range of normal value. Serum homocysteine value in pregnant women was 7.1 ± 1.95 µg/mL with a range of 3.0 to 10.9 µg/mL, while normal value was 5 to 15 µg/dL.Conclusion: homocysteine, folic acid, pregnant women, anemia. 
KEKURANGAN VITAMIN A PADA KELOMPOK BAYI DAN FAKTOR YANG BERHUBUNGAN DI KABUPATEN BOGOR Muherdiyatiningsih Muherdiyatiningsih; Nuning M. Kiptiyah; Muhilal Muhilal; Sri Martuti; Frank T. Wieringa; Marjoleine A. Dijkhuizen
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 26 No. 2 (2003)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v26i2.1432.

Abstract

VITAMIN A DEFICIENCY AND ITS RELATED FACTORS IN INFANTS IN BOGOR DISTRICT.Background: Based on clinical indicators, vitamin A deficiency in Indonesia is not a public health problem because the prevalence of xerophthalmia has been decreased to 0.34%. But, this decrease has not been followed by a decrease of marginal deficiency of vitamin A in vulnerable groups, especially infants.Methods: The cross-sectional baseline study was conducted at Bogor District. The aim of the study was to collect information about the vitamin A status of the breastfed infant, and to look for a relationship between many factors related to it. The samples were 183 breastfed infants aged 2-0 months without chronic disease, congenital disease, severe PEM nor twins. The chi-square and the prevalence odds ratio (POR) at the 95% confidence interval were used to measure the association between variables. Multiple logistic regression analysis was used to measure the closest factors to infant's vitamin A status.Results: The study showed that 54.1% of breastfed infants were at risk of vitamin A deficiency. Based on bivariate analysis, there are two significant independent variables related to infants vitamin A status, which are maternal vitamin A status and infant infection status. Multiple logistic regression analysis showed that infection status is the closest factor to vitamin A deficiency in infants, followed by maternal vitamin A status and breast feeding frequency. There are no significant association between supplementary feeding, age, nutritional status and the infant's vitamin A status.Conclusions: Marginal vitamin A deficiency in infants aged 2-10 months is still a public health problem in the research area. The infection status is the closest factor to vitamin A deficiency in infants, followed by maternal vitamin A status and breast feeding frequency.Keywords: vitamin A deficiency, breast feeding, infection, complementary feeding, infant