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All Journal Damianus Journal of Medicine MITRA: Jurnal Pemberdayaan Masyarakat Jurnal Ilmu Kedokteran dan Kesehatan Acta Biochimica Indonesiana Jurnal Muara Sains, Teknologi, Kedokteran dan Ilmu Kesehatan Jurnal Bakti Masyarakat Indonesia Jurnal Kesehatan Tambusai Devotion: Journal of Research and Community Service Prosiding Seri Seminar Nasional Jurnal Suara Pengabdian 45 NUSANTARA: Jurnal Pengabdian Kepada Masyarakat KREATIF: Jurnal Pengabdian Masyarakat Nusantara Jurnal Sehat Indonesia (JUSINDO) Tarumanagara Medical Journal Perigel: Jurnal Penyuluhan Masyarakat Indonesia Jurnal Keperawatan Bunda Delima Jurnal Pengabdian West Science Jurnal Abdimas Indonesia Jurnal Muara Medika dan Psikologi Klinis Jurnal Pengabdian Masyarakat Nian Tana Jurnal Pengabdian Sosial Panggung Kebaikan : Jurnal Pengabdian Sosial Cermin Dunia Kedokteran Jurnal Serina Abdimas KREATIF: Jurnal Pengabdian Masyarakat Nusantara
David Limanan
Bagian Biokimia Dan Biologi Molekuler Fakultas Kedokteran Universitas Tarumanagara, Jakarta, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : Devotion: Journal of Research and Community Service

 1 
Antioxidant Test, Total Alkaloid Content, Antimitosis Test and HPTLC Test of Chamomile Flower Extract (Matricaria Chamomilla L.) Tantowi, Ferdy; Limanan, David
Devotion : Journal of Research and Community Service Vol. 4 No. 1 (2023): Devotion: Journal of Research and Community Service
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/dev.v4i1.351

Abstract

Oxygen is one of the supports of multicellular life and is necessary for aerobic metabolism. However, the use of oxygen can produce by-products, one of which is reactive oxygen species (ROS) which can also increase due to external factors such as exposure to ionizing rays, and vehicle smoke. When reactive oxygen species levels are high, the body can experience a condition called oxidative stress, which is a condition that can cause tissue damage. To overcome this, antioxidants are needed, namely compounds that can donate electrons to free radicals to neutralize their effects. Antioxidants are divided into endogenous antioxidants and exogenous antioxidants. Endogenous antioxidants are antioxidants found in the body. Exogenous antioxidants are antioxidants that come from outside the body. Because there is an increase in ROS levels due to external influences, an increase in exogenous antioxidants is needed, one of which is chamomile flowers. This study evaluated qualitative phytochemical levels using the Harnborne method, total antioxidant capacity using the Blois method, total quantitative levels of alkaloids using the Trivedi et al method, BSLT toxicity using the Meyer method, and fingerprint analysis using HPTLC. The obtained chamomile flowers are dried and extracted by maceration using methanol solvent. The test results on chamomile flowers revealed phytochemical content in the form of alkaloids, betasianin, cardioglycosides, coumarins, flavonoids, phenols, quinones, saponins, steroids, tepenoids and tannins. Antioxidant ability 209.27 g/ml; Total alkaloid content of 12.62 g/ml; toxicity 174.39 g/mL; As well as fingerprint analysis chamomile flowers have active ingredients. Therefore, chamomile flowers can serve as a moderate antioxidant with antimitotic activity.
Antioxidant Capacity Test, Total Phenolic, Total Alkaloid, and Toxicity of Marigold Flower (Tagetes Erecta L.) Tenggono Son, Hadinata; Limanan, David
Devotion : Journal of Research and Community Service Vol. 4 No. 1 (2023): Devotion: Journal of Research and Community Service
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/dev.v4i1.352

Abstract

Antioxidants are a set of compounds that can fight the effects of reactive oxygen species (ROS) so as to eliminate their effects in the form of damage to macromolecules of carbohydrates, fats, proteins, and DNA chains. One source of antioxidants that are easily available and widely available is through herbal ingredients such as marigold flowers (Tagetes erecta L.). Marigold flowers are well known and used as a source of antioxidants, anti-inflammatory, antibacterial, diuretic and accelerate wound healing. This flower is often consumed as an edible flower and is also drunk in the form of tea. This study aims to look for the antioxidant capacity, total phenolic, total alkaloids, and toxicity of marigold flowers. Marigold flower extract is obtained by evaporating the results of methanol maceration from dried marigold flowers. Test antioxidant capacity with DPPH (2,2-diphenyl-1-picrilhydrazyl) using Blois method, total phenolic using Singleton and Rossi method, total alkaloid by method by Trivedi et al, and BSLT toxicity by Meyer method. The antioxidant capacity of marigold flowers is measured in IC50 as much as 74.5 μg/mL which includes active antioxidant levels. The total phenolic content of marigold flowers was obtained as much as 10,350.68 μg/mL. Total alkaloid levels were obtained as much as 13.05 μg/mL. The BSLT toxicity test in LC50 is 162.82 μg/mL which is categorized as moderate toxicity. From the results of this study, marigold flowers can be used as a source of antioxidants and have antimitotic properties.
Co-Authors Akhmad, Fariz Azril Khaidar Alexander Halim Santoso Alexander Halim Santoso Alphanto, Alfred H Alya Dwiana Andrea Bianca Castafiore Kusuma Angela Aprilia Adinda Annisaa Nurrahma Ardyati Ardhita Felicia Tanuhariono Asyraf, Muhammad Zain Alwi Audina Leonita Clareta Vero Patricia Widya Darma, Timothy Halomoan Destianti , Erika Dwiana, Alya E Efrany E Yulianti Edbert, Bruce Edwin Destra Eldy Eny Yulianti Eny Yulianti Eny Yulianti Eny Yulianti Eny Yulianti Eny Yulianti Eny Yulianti, Eny Erics Efrany Ezra, Pasuarja Jeranding F Wandy Farell Christian Gunaidi Felicia Tanuhariono, Ardhita Ferdian Ferdian Frans Ferdinal Frans Ferdinal Frans Ferdinal Frans Ferdinal Frans Ferdinal Fransiska Iriani Dewi Freddy Ciptono Gaofman, Brian Albert Gita Manerlin Kasihita Simatupang Grace Madeleine Halomoan Darma, Timothy Helmi Rizal Helmi Ivany Lius Pangestu Jap, Ayleen Jeffrey Jeffrey Jeffrey Saputra Kawi Jessica Geselda Salim Julianty, Eny Karinnia Karinnia Kevin Arya Lim Kusuma, Andrea Bianca Castafiore Lontoh, Susy Olivia Lulu Lina Azzahrotin Fairuza M Lirendra Maharani, Ismi Ikrima Makarau, Erick Marcella E. Rumawas Marcella, Agnes Marcellino, Marcellino Maria Christina Dwiyanti Meilani Kumala Michael Chen Muhammad Fikri Dzakwan Natasha Olivia Christian Nawaika Shafira Putri Ngestinuari Salim NO Christian Olivia, Susy Putri, Nawaika Shafira Putri, Viola Ananda Jerika R Benettan Rizky Putri Agustina Rudianti, Selly Herlia Rumawas, Marcella E Rumawas, Marcella E. Rumengan, Peterjohn Andrew Benhard Saerang, Stefanus Handy Salim, Melanie Santoso, Alexander Santoso, Alexander Halim Sari Mariyati Dewi Nataprawira Sentosa, Belinda Septiana, Devqa Nur Setiady, Brandon Alexander Shafira Putri, Nawaika Sidarta, Erick Stephanie Amadea Susy Olivia Susy Olivia Susy Olivia Lontoh Susy Olivia Lontoh Tantowi, Ferdy Tanuhariono, Ardhita Felicia Teguh, Stanislas Teguh, Stanislas Kotska Marvel Mayello Tenggono Son, Hadinata Timotius Timotius Tjahyanto, Teddy Tjie Haming Setiadi Tjie Haming Setiadi Triyana Sari Wijayadi, Linda Julianti yanto, heri Yesan Suci Paramitha