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Nurwijayanti
Universitas STRADA Indonesia
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The Role of Nutritional Status in the Quality of Life (QoL) of PLHIV Hasrul; Ida Nurwati; Joko Prasetyo; Rahmania Ambarika; Nurwijayanti; Atik Setiawan Wahyuningsih
Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Vol. 9 No. 9 (2026): In Progress
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/mppki.v9i9.10729

Abstract

Introduction: Despite significant advances in antiretroviral therapy (ART), multiple factors continue to be associated with the Quality of Life (QoL) among people living with HIV (PLHIV). Although nutritional status may play an important biological role in the observed relationships, limited evidence exists regarding its statistical mediating role between behavioural, environmental, personal, and metacognitive factors and QoL among PLHIV receiving long-term treatment. Methods: This study employed an analytical cross-sectional design using Structural Equation Modelling–Partial Least Squares (SEM-PLS). Participants were selected using purposive sampling based on predefined inclusion criteria. Sample size adequacy was determined using the 10-fold rule and G*Power analysis with a medium effect size (f² = 0.15), significance level of 0.05, and statistical power of 0.80. A total of 127 PLHIV receiving ART participated in the study. Results: Among 126 PLHIV analysed (purposive, service-based sample), the measurement model showed strong convergent validity (AVE > 0.80) and reliability (Cronbach’s alpha > 0.89). Personal, behavioural, environmental, and metacognitive factors were each significantly associated with nutritional status, with personal factors showing the strongest effect (β = 0.468; p < 0.001). Nutritional status, in turn, was significantly associated with Quality of Life (β = 0.746; p < 0.001), while none of the four determinants showed a significant direct association with QoL once nutritional status entered the model. Bootstrapped indirect effects were significant for all four determinants (β = 0.249 to 0.349; 95% CI excluding zero), a pattern consistent with a statistical mediation model rather than evidence of a causal mechanism. The structural model accounted for 66.2% of the variance in QoL (R² = 0.662). Conclusion: In this cross-sectional sample of PLHIV aged 30 years and above, nutritional status showed a statistical pattern consistent with mediating the associations between personal, behavioural, environmental, and metacognitive factors and Quality of Life, explaining 66.2% of its variance (R² = 0.662). These findings should be read as hypothesis-generating rather than proof of a causal pathway, given the cross-sectional design.
Co-Authors Abiddin, Andi Hayyun Adetya Wahyu Dwi Jaya Adriana Novi Ndiken Agung Cahyono Agung Sudibdyo Agus Khoirul Anam Agus Setiyawan Agusta Dian Agusta Dian E Agusta Dian Ellina Agustin Widyowati Agustin, Evi Avicenna Alfi Yudisianto Alfi Yudisianto Ana Solikah Andi Hayyun Abiddin Andin Ajeng Rahmawati Anwar, Muhammad Choirul Apir Arfah, Andi Muh Arif Mustofa Armando Hadyono JS Atik Setiawan Wahyuningsih Aulia Rahman Billy Anoraga, Aditya Butar-Butar, Maria Haryanti Byba Melda Suhita Byba Melda Suhita Byba Melda Suhita Chusnul Justanti Dali, Agus Salim Derlin Firnawati Dhandi Hidayatullah Diyah Herowati Diyana Juli Pangastuti Duri, Vinca Rosa Swastika Ekawati Wasis Wijayati ellina, agusta dian Emy Ismiaty, Emy Ester Lita Maratade Evi Kurniawati Farida Farida Fika Istikah Firman Yudianto Fitria Yusti Ningrum Fresvian Jenrivo Fridolin Dapa Dadu Gempi Tri Sumini Gretta Hapsari Amalya Gretta Hapsari Amalya Hadi Santoso Hamzah Arof Hasrul Heru Eko Susanto Hesky Frengky Ngongoloy Ida Nurwati Indah Triningsih Indasah Indasah Ira Nurdiana Irwan Syahputra, Irwan Isa Harpika Izzah El Maila Jalu, Prastyantoko Kukuh Jamilatus Sholeha Jian Bagas Wara Joko Prasetyo Joko Prasetyo Joko Prasetyo Josefina Neltji Malisngorar Jufenti Ade Fitri Junaidi, Anang Koesnadi Koesnadi Kurnia Wira Susanti Laily Nurhanifah Lasito Lasito Lia Retno Wulan Sari Maria Nubatonis Maria Rante Tandung Marintas Marintas Martins, Noelio Auxilio Pedro Miftakhul Muthohiroh Mochammad Romli Arief Muhammad Saleh Muji Murtiningsih Nancy Natalia Dharmawan Nanik Kusyani Ning Arti Wulandari Nisa Diani Amalia Novita Ana Anggraini Novita Ana Anggraini Novita Anna Anggraeni Nur Aini Fatimah Nurdina Nurdina Nurdina Nurdina Nurdina Nurdina Nurlely Tri Wahyuni Nurlely Triwahyuni Nurullita Widyazizah Nusantarie, Krit Mahayuning Oktofianus Radja Tuka Osnawati H. Marsaoly Panca Radono Panca Radono Parinding, Yunus Poni Angelia Poppy Hidayat Poppy Hidayat Priawan, Hendra Prima Dewi Prima Dewi Dewi Prima Dewi Kusumawati Putri Retno Wijaya Radiktyasari, Asty Rahayu Budi Utami Rahmania Ambarika Rahmania Ambarika Rahmania Ambarika Rahmania Ambarika Ratna Wardani Ratna Wardani Ratna Wardani Ratna Wardani Raudatul Hikmah Reny Tri Febriani Rima Faradila Ririt Ika Lestari Rischa Devi Hayuningtyas Risyan Karnain Risyan Karnain Rita Sugihati Riza Tsalatsatul Mufida Rizky Amalia Sinulungga Rosalia Astria Tanggu S Ruri Firmansyah Rusiana Rahayu Ryan Hidayatullah Sad Omega Kencanawaty Sad Omega Kencanawaty Salsabila, Unik Hanifah Samad, Andi Muh. Arfah Saputra Sandu Siyoto Sandu Siyoto, Sandu Sasmita, Hasri Yulia Sentot Imam Suprapto Sentot Imam Suprapto Sentot Imam Suprapto Siska Saidi Rizali Sismulyanto Siswati, Heni Siswati, Heni Siti Farida Siti Farida Noor Laila Sofyan Wahyu Sofyan Wahyu Kumara Sri Kardjati Sri Kardjati Maria Sri Sumiarsih Sri Wahyuningsih Sri Yuni Windu Puri Sudewa, I Gusti Ngurah Wisnu Sugiati Sugiati Sumiati Sumiati Sunyoto Sunyoto Supriyanto Supriyanto Suwarsi Suwarsi Tallupadang, Resty Titien Altini Hidayat Tri Hari Wahyuningtyas Tutus Fibri Ajimas Budi Wahyuni, Retno Dwi Wardani, Silvia Intan Wening Palupi Dewi Widiani Retnaningsih Winda Gusya Wuryani, Denik Yenny Puspitasari Yohanes Deo Fau Yuli Peristiowati Yuli Peristiowati, Yuli Yuly Periostiawati Yuly Peristiowati Yuly Peristiowati Zuhrotul Aini Zulkipli Abdullah Usin Zulkipli Zulkipli