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Journal : JOURNAL LA MEDIHEALTICO

Correlation between Adherence and Effectiveness of Tuberculosis Medication Use among Patients Zuniarto, Ahmad Azrul; TW, Siti Pandanwangi; Annisa, Fatin Maura
Journal La Medihealtico Vol. 5 No. 3 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i3.1281

Abstract

Indonesia has become the country with the second highest number of tuberculosis cases in the world. In 2021, Indonesia recorded an incidence of 397,377 cases, with a significant number of cases originating from Tegal, Central Java, which reported 980 cases. The purpose of this study is to determine the compliance and effectiveness of TB medication usage and to examine the relationship between compliance, effectiveness, and patient sociodemographics. The study population consists of tuberculosis patients at the Tegal Selatan Community Health Center who underwent treatment from September 2023 to February 2024. The research method is quantitative causal. Data collection was conducted both retrospectively and prospectively. Compliance data were obtained through the MMAS-8 questionnaire, and effectiveness data were gathered by recording follow-up sputum examinations using the SITB (Tuberculosis Information System) software. The study included 30 respondents, with 50% male and 50% female. The majority (63.3%) were middle-aged adults (41-60 years old), 63.3% had less than 9 years of education, 60% were employed, 93.3% had an income at or below the minimum city wage, and 70% had 1-3 family dependents. 76.7% of respondents exhibited high compliance, 20% had moderate compliance, and 3.3% had low compliance. The effectiveness of medication usage was 96.7%. Chi-square analysis (95% CI) revealed a strong correlation between compliance and effectiveness with r = 0.707 (p-value = 0.033), and there was no significant relationship between patient sociodemographics and both compliance and effectiveness.
Antibacterial Activity of Katang-Katang Leaf Extract Gel against Staphyloccus Aureus Haryati, Eti; Sugiarto, Anto; Zuniarto, Ahmad Azrul; Hakkin, Atini Sabila
Journal La Medihealtico Vol. 6 No. 3 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i3.1737

Abstract

Infectious diseases are one of the health problems faced by developing countries such as Indonesia. Various methods are used to treat skin infections caused by Staphylococcus aureus bacteria, one of which is traditionally using plants, namely katang-katang leaves which have active compounds of flavonoids, alkaloids, saponins and tannins as antibacterials. This study aims to determine the antibacterial activity of the gel preparation of katang-katang leaf extract (Ipomea pes-caprae) to determine the concentration that has the greatest antibacterial activity and to determine the physical properties. Gel preparations were made with concentrations of 15%, 20%, and 25%. The test method was carried out using the in vitro disc diffusion method and physical properties tests were carried out which included organoleptic tests, homogeneity tests, pH tests, spreadability tests, adhesion tests and viscosity tests. Data analysis was carried out using normality tests, homogeneity tests, anova and post hoc test. The results of research testing the antibacterial activity of katang-katang leaf extract gel at a concentration of 15% was 3.27 mm, 20% was 4.97%, 25% was 5.97 mm, K+ was 10.97 mm and K- was 0 mm. Katang-katang leaf extract gel has antbacterial activity that is not equivalent to the positive control, katang-katang leaf extract gel does not meet the preparation evaluation requirements and is unstable during storage. From these results it can be concluded that the katang-katang leaf extract gel has antibacterial activity against Staphylococcus aureus and the katang-katang leaf extract gel does meet the preparation evaluation requirements and is unstable during storage.
Co-Authors , stf1 ., Rodiya ., Sutisno Afief, Arief R. Ais Hamidah Aisy, Asri Rihadatul Akbar, Rai Fadiilah Akrom, Akrom Amanatin, Alfitia Dwi Andriswana, Dwi Meiria Anjastika, Luky Septiansyah Anna Pradiningsih Annisa, Fatin Maura Antonia, Vonny apriliasanti, Wahyuni Auliya, Muhammad Febri Ayuditiawati, Meita Ita Cantika, Dwi Putri Dewi, Komala Fatmawati, Eva Fauzia, Rizki Rahmah Haerunnisa, Tita Hakkin, Atini Sabila HARYATI, ETI Hasimun, Patonah Husni Mubarok Joharudin, Ade Karlina, Elis Karphiawati, Aldilla Shalsa Karsidin, Bambang Mardhiyyah, Cut Ainul Maulida, Nur Afifah Mega Suryani, Mega Meiria A, Dwi Mundzir, Ahmad Mundzir, O Ahmad Mundzir, O. Ahmad Nafi'ah, Rahma Nafilah, Nella Nahdliyah, Vivi Afiyatun Ndang Ikbal Maulana Nopita, Juwita noviani, Adis Novianti, Sari Nuari, Ris Ayu Nur Imam Komara Nurfaizi, Deni Nurhasanah, Sarah Nurkhasanah Nurkhasanah Nurkhasanah Putera, Rizky Medino Regar, Dhea Novakinanda Rustanti, Mega Ryansyah, Hardi Sabarudin, Cecep Saefullah, Indah Silviyanti Setriyadi, Dedy Siti Pandanwangi TW Siti Pandawangi TW Sodik, Jajang Japar Subagja . Subagja, Subagja Sugiarto, Anto Sugiharto, Anto Sugiharto, Yuyun Suhada, Tatik Sofiyani Suharmono, Soni Sumari Sumari Sundari, Retno T Supriatna, Cece Susanti, Nina Pratiwi Tamala, Nur Feggy Tanti Tanujaya, Jojon Titiek Suhardi Haripurnomo Kushadiwijaya Hidayati Tsai, Mei Ling TW, Siti Pandanwangi Wahyuni, Yenny Sri Widianingsih, Nining Yani, Dosi Ahmad Yuniuswoyo, Wirsad Yusniawati, Feni Zakiah, Fitri Zakiyah, Fitri Zanki, Alfriani Melia