Article Per Year (5 Year)
p-Index From 2020 - 2025
2.686
P-Index
This Author published in this journals
All Journal International Journal of Public Health Science (IJPHS) JURNAL GIZI INDONESIA Jurnal Kedokteran Diponegoro Althea Medical Journal Jurnal Keolahragaan Journal of Biomedicine and Translational Research Jurnal Penelitian Pendidikan IPA (JPPIPA) IJEMS (Indonesian Journal of Environmental Management and Sustainability) JOURNAL SPORT AREA Journal of Dedicators Community PREPOTIF : Jurnal Kesehatan Masyarakat Narra J JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Eduvest - Journal of Universal Studies Jurnal Keperawatan Indonesian Journal of Biomedicine and Clinical Sciences
Muniroh, Muflihatul
Unknown Affiliation
Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Education Energy Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

Published : 19 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Indonesian Journal of Biomedicine and Clinical Sciences

 1 
In vivo assay of Gigantochloa apus shoot extract as biolarvicide for myiasis-causing fly larvae Sadana, Aqsa Aufa Syauqi; Istiadi, Hermawan; Halleyantoro, Ryan; Muniroh, Muflihatul
Indonesian Journal of Biomedicine and Clinical Sciences Vol 57 No 4 (2025)
Publisher : Published by Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/inajbcs.v57i4.16307

Abstract

The use of synthetic insecticides in treating myiasis is associated with adverse side effects and potential disruption of metabolic systems, prompting interest in natural alternatives. This study investigated the in vivo larvicidal efficacy of Gigantochloa apus bamboo shoot extract, formulated as a spray gel. Twenty-five Wistar rats were randomly divided into 5 groups: a negative control group, a positive control (ivermectin), and 3 treatment groups receiving of 1%, 3%, and 5% G. apus bamboo shoot extract. Myiasis was induced by introducing fly larvae into standardized wounds. Treatments were applied topically twice daily for 32 hr, and larval mortality was assessed every 8 hr. Phytochemical screening and GC-MS analysis revealed the presence of bioactive compounds, including alkaloids, flavonoids, tannins, saponins, and hydrogen cyanide, all of which are known for their larvicidal, neurotoxic, and antiproliferative properties. The 5% extract group showed the highest mortality rate (100%) at 32 hr. The LC50 and LC95 values were determined at 1.43% and 6.01%, respectively. Compared to the standard ivermectin treatment, the 5% extract demonstrated a shorter lethal time and more rapid larval death. Morphological examination revealed darker abdominal segments in the dead larvae, indicating a potential interaction with the digestive tract. These findings indicate that G. apus bamboo shoot extract has potential larvicidal activity and can be an effective natural alternative for treating myiasis.
Co-Authors - Anggorowati Adriyan Pramono Afriana, Rizky Dyas Ahmad Syauqy Ani Margawati Anjani, Gemala Annastasia Ediati Annisa Pratiwi, Annisa Apoina Kartini Ardyarini, Hikmatunnisa Tri Ariani, Mahayu D. Ariosta Ariosta Awal Prasetyo Besari Adi Pramono Bintang, Francisca Natalia Budiono, Bernadus Parish Diana Nur Afifah, Diana Nur Djuara P Lubis Elsa Naviati Endang Sri Lestari Etika Ratna Noer Fitry, Febriana Ramadhani Hadiprajitno, Peter I. Halleyantoro, Ryan Hardhono Susanto Hermawan Istiadi Julian Dewantiningrum Juniarto, Achmad Z. Karlowee, Vega Kesuma, Erlangga Hadi Kesumayadi, Irfan Kis Djamiatun Mambaya, Helvi Desi Mohammad Sulchan Muhammad Nur Muhammad Sulchan Nani Maharani Natalia Dewi Wardani Nugraha, Eka Djatnika Nur, Muhammad Hasbi Nyoman Suci Widyastiti Partiwi, Rina Perdanawati, Mia Qolby, Qonita Nur Renni Yuniati Retnoningrum, Dwi Sadana, Aqsa Aufa Syauqi Sekartaji, Anindhita Dyah Septiani, Bernadeta Novita Sigit Adi Prasetyo, Sigit Adi Sri Achadi Nugraheni Untung Sujianto Utami, Arini Veni, Rizka Widyastuti, Trioni Yetty Movieta Nency, Yetty Movieta Yora Nindita Yosef Purwoko Zetta, Adelia Paradya