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All Journal International Journal of Public Health Science (IJPHS) JURNAL GIZI INDONESIA Jurnal Kedokteran Diponegoro Althea Medical Journal Jurnal Keolahragaan Journal of Biomedicine and Translational Research IJEMS (Indonesian Journal of Environmental Management and Sustainability) JOURNAL SPORT AREA Journal of Dedicators Community PREPOTIF : Jurnal Kesehatan Masyarakat Narra J Jurnal Keperawatan
Muniroh, Muflihatul
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Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Education Energy Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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PERBEDAAN MEMORI JANGKA PENDEK SEBELUM DAN SESUDAH MENDENGARKAN MUSIK SAAT LARI PADA DEWASA MUDA Ardyarini, Hikmatunnisa Tri; Muniroh, Muflihatul; Maharani, Nani
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 7, No 2 (2018): JURNAL KEDOKTERAN DIPONEGORO
Publisher : DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (418.651 KB)

Abstract

Latar Belakang: Mendengarkan musik saat berolahraga diketahui dapat menimbulkan efek ergogenik dan mempengaruhi sistem kardiovaskuler. Namun, pengaruh kombinasi keduanya terhadap memori, sebagai salah satu fungsi kognitif yang penting pada proses pembelajaran usia dewasa muda, masih belum diteliti lebih lanjut.Tujuan: Mengetahui perbedaan memori jangka pendek sebelum dan sesudah mendengarkan musik saat lari pada kelompok dewasa muda.Metode: Penelitian eksperimental dengan metode pre- dan post-test unequivalent group di Stadion Universitas Diponegoro. Subjek adalah kelompok usia dewasa muda (17-22 tahun) yang pada periode penelitian tercatat sebagai mahasiswa Fakultas Kedokteran Universitas Diponegoro (n=40) dan dipilih secara purposive sampling, kemudian dibagi menjadi 2 kelompok; kelompok lari selama 30 menit dengan mendengarkan musik (n=20) dan kelompok lari selama 30 menit tanpa medengarkan musik sebagai kontrol (n=20). Memori jangka pendek diukur dengan Scenery Picture Memory Test dan analisis data dilakukan dengan uji t-berpasangan, t-tidak berpasangan, Wilcoxon dan Mann-Whitney.Hasil: Terdapat perbedaan memori jangka pendek yang bermakna sebelum dan sesudah mendengarkan musik saat lari (p=0,00). Memori jangka pendek setelah lari dengan mendengarkan musik meningkat secara signifikan (p<0,05) dibandingkan dengan kontrol, dengan rerata peningkatan sebesar 5,0 ± 2,66 pada kelompok lari dengan mendengarkan musik dan 3,05 ± 1,76 pada kelompok kontrol.Kesimpulan: Mendengarkan musik saat lari dapat meningkatkan fungsi memori jangka pendek lebih tinggi dibandingkan dengan lari tanpa mendengarkan musik pada usia dewasa muda.
Particular Matter of Motor Vehicle Exposure and High-Fat Diet Effects on Kidney Histopathology, Creatinine, and Malondialdehyde (MDA) Levels in Wistar Rats Veni, Rizka; Prasetyo, Awal; Muniroh, Muflihatul
Indonesian Journal of Environmental Management and Sustainability Vol. 5 No. 3 (2021): September
Publisher : Research Centre of Inorganic Materials and Complexs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/ijems.2021.5.3.124-128

Abstract

This study aims to analyze the effect of combination of motor vehicle particular matter exposure and high-fat diet in kidney histopathology, creatinine levels, and MDA levels in Wistar rats. This study used a posttest-only control group design. Eighteen healthy male Wistar rats were divided into three groups. The intervention groups received motor vehicle fume exposure for 100 s with normal diet (X1) or high-fat diet (X2), and the control group received no exposure (C). Data analysis was processed with a SPSS 25.0 computer program by using the one-way ANOVA test followed by post hoc LSD. The degree of kidney histopathological damage showed significant differences between the X1 and X2 groups when compared with the control group (p < 0.05). The results of the creatinine level examination found a significant difference between the X2 and C groups (p < 0.05) and the treatment groups X1 and X2 (p < 0.05). The results of kidney MDA level examination showed a significant difference between the treatment groups (X1 and X2) and the control group (p < 0.05). The combination of particular matter of motor vehicle fumes exposure and high-fat diet could induce kidney damage through histopathological change and increased creatinine levels and kidney MDA levels in Wistar rats.
Sorghum Tempeh on Cholesterol Levels and Histopathology of Aorta in High-Fat Diet-Induced Rat Model Bintang, Francisca Natalia; Lestari, Endang Sri; Afifah, Diana Nur; Muniroh, Muflihatul; Anjani, Gemala; Syauqy, Ahmad; Djamiatun, Kis
Journal of Biomedicine and Translational Research Vol 10, No 2 (2024): August 2024
Publisher : Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v10i2.22689

Abstract

Background: Elevated cholesterol levels are associated with hypercholesterolemia, the primary cause of death and lost productivity, and a significant risk factor for the onset of cardiovascular disease. Sorghum is known for its high bioactive components and phenolic compounds, flavonoids, β-glucans, and dietary fiber, which act as anti-cholesterol properties.Objective: This study aimed to analyze the impact of sorghum tempeh on cholesterol levels and histopathology of aorta in rats fed a high-fat diet.Methods: A total of 24 male 8-weeks-old Sprague Dawley rats were randomly assigned to four groups: standard diet group (SD), high-fat diet control group (FD), rats fed high-fat diet + low dose of sorghum tempeh (T1), and high-fat diet + high dose of sorghum tempeh (T2). Measurements of cholesterol levels were determined using the total cholesterol ELISA method. Histopathology of aorta analysis was carried out after four weeks of intervention of the four treatment groups using Hematoxylin-Eosin staining.Results: The average total cholesterol levels post-intervention in the SD, FD, T1, and T2 were 89.986±2.089, 220.365±3.847, 121.161±4.111, and 97.836±2.504 mg/dL, respectively. The results showed that the total cholesterol level significantly decreased (p<0.05) after giving a formula of sorghum tempeh with doses of 0.75 g and 1.50 g per 200 g body weight of rats for four continuous weeks. Histopathology of the aorta in the FD and T2 groups showed a significant difference compared to the SD group. The result which was closest to the SD group was the T1 group.Conclusion: Sorghum tempeh is a high-fiber and antioxidant source that can control hypercholesterolemia by lowering serum total cholesterol. It is also possible to improve histopathology but not yet able to approach normal conditions. The administration of sorghum tempeh with a low dose is sufficient, and further research is still required to determine the effect of sorghum tempeh on aorta histopathology.
Garcinia Mangostana Pericarp Extract Protection on Reproductive Function of Obese-Diabetic Rats Model Nindita, Yora; Karlowee, Vega; Kesumayadi, Irfan; Istiadi, Hermawan; Muniroh, Muflihatul
Althea Medical Journal Vol 10, No 3 (2023)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v10n3.2905

Abstract

Background: Type 2 diabetes mellitus (T2DM) in obese has been considered a risk factor for male infertility. Garcinia mangostana pericarp extract (GMPE) is known to have anti-hyperglycemic, anti-diabetic, and anti-inflammatory effects. This study aimed to evaluate the effect of GMPE therapy on reproductive function in obese T2DM rats by examining testosterone level, testicular histopathological features, and hs-CRP level.Methods: Thirty-six male Wistar rats, aged 2–3 months, were randomly divided into 6 groups and treated with a standard diet (NC), high-fat diet (HFD) with GMPE 200 mg/kgBW (obese GMPE control/OGC200), HFD with 45 mg/kgBW STZ-NA (obese-diabetic control/ODC), obese-diabetic rats with GMPE 100 (DG100); 200 (DG200); and 400 mg/kgBW (DG400). STZ-NA was administered after 8 weeks of HFD treatment and followed by GMPE for 8 weeks after T2DM was confirmed. The level of hs-CRP and testosterone were measured in the serum using an enzyme-linked immunosorbent assay. Testicular histopathological examination was measured after 8 weeks of treatment by using Modified Jonhson Score (MJS) with HE staining. Results: ODC rats significantly showed increased hs-CRP level compared to NC (8.76±0.27 vs 0.30±0.07 ng/mL, p<0.001) and reduced testosterone level and MJS compared to NC (73.69±2.22 vs 170.14±1.34 ng/dL, 4.57±0.93 vs 9.87±0.16 MJS, respectively, P<0.001). Testosterone and hs-CRP levels showed a negative and significant correlation (r=-0.974 and p<0.001). On the treatment group, GMPE significantly reduced hs-CRP and increased testosterone levels in a dose-dependent manner.Conclusion: GMPE effectively protects reproductive function in obese DM rats by increasing testosterone levels and advanced spermatogenesis, as well as decreasing hs-CRP level
Maternal hair lead and cytokine pro-inflammatory effects in preterm birth Qolby, Qonita Nur; Dewantiningrum, Julian; Pramono, Besari Adi; Maharani, Nani; Nugraha, Eka Djatnika; Muniroh, Muflihatul
International Journal of Public Health Science (IJPHS) Vol 13, No 4: December 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i4.24146

Abstract

This case-control study analyzed the lead (Pb), interleukin 6 (IL-6), and tumor necrosis factor alpha (TNF-α) levels in pregnant women with preterm birth (PTB) in Central Java, Indonesia. Hair samples from 72 pregnant women were collected non-invasively. The prenatal exposure to Pb was determined with the total reflection X-ray fluorescence (TXRF) method. Serum IL-6 and TNF-α were examined using enzyme-linked immunosorbent assays (ELISA). The Pb concentration in hair was slightly higher in women with PTB than those without PTB; however, this difference was not statistically significant. An elevated hair Pb level was not associated with increased PTB risk (OR 24.69, 95% CI 0.93–653.82, p>0.05). A serum TNF-α level ≥27 pg/ml, a serum IL-6 level ≥9 pg/ml, and the spouse’s smoking frequency were significantly associated with increased PTB risk (TNF-α OR 42.25, 95% CI 5.26–339.61; IL-6 OR 22.33, 95% CI 3.12–158.54; spouse’s smoking frequency OR 1.28, 95% CI 1.09–1.5), while the maternal hemoglobin concentration significantly decreased PTB risk (OR 0.43, 95% CI 0.2–0.927). This study demonstrates that maternal hair Pb concentration has no significant relationship with PTB. Serum TNF-α, IL-6, and the spouse’s smoking frequency potentially increased PTB risk, while the maternal hemoglobin level is a protective factor.
Nutrition intake, insulin-like growth factor-1 hormone levels, somatotype score, and strength performance of adolescent athletes Zetta, Adelia Paradya; Susanto, Hardhono; Noer, Etika Ratna; Muniroh, Muflihatul; Widyastiti, Nyoman Suci
Journal Sport Area Vol 9 No 3 (2024): December
Publisher : UIR Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25299/sportarea.2024.vol9(3).17017

Abstract

Background Problems: Currently, there is still limited identification of nutritional intake, hormonal, and physical performance in adolescent athletes in Indonesia. Research Objectives: This study aims to identify anthropometric, nutritional intake, IGF-1 hormone level, and adolescent athletes’s performance. Methods: The research method used a cross-sectional study. A convenient sample of 58 athletes under Balai Pemusatan Pendidikan dan Latihan Pelajar. The research instrument used Bioelectrical Impedance Analysis (BIA), leg dynamometer, hand grip dynamometer, tape measure, height stature, SQ-FFQ Form, and body fat caliper. Blood samples were collected and tested by a professional laboratory. Data analysis techniques used Pearson’s test for normally distributed data and Spearman’s rank for non-normally distributed data. Findings and Results: The result of this study found a significant (p < 0.05) correlation between energy intake, anthropometric measurement of z score (BMI/Age), and endomorph score with an athlete’s muscle strength. We also found significant differences (p < 0.05) in macronutrient and micronutrient consumption in male and female athletes, and we also found significant differences in somatotype score and muscle strength in male and female athletes. Conclusion: We conclude that many athletes are not consuming the recommended levels of carbohydrates, fat, protein, and some micronutrients. We found a correlation between energy intake and fat intake with leg muscle strength. However, there was no correlation between IGF-1 hormone levels and athlete strength. Intake is thought to indirectly affect grip strength and leg strength.
The Effect of Benson’s Relaxation Therapy on Stress Levels Among Medical Students Diponegoro University Who Were Working on a Thesis Kesuma, Erlangga Hadi; Purwoko, Yosef; Muniroh, Muflihatul; Wardani, Natalia Dewi
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 3 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i3.42108

Abstract

Background: The prevalence of stress in final-year students who were working on a thesis was still quite high. Unmanaged stress could bring a negative impact on the students themselves. Benson’s relaxation therapy was a relaxation that combined deep breathing techniques with faith factor and had been known to reduce stress levels. This relaxation was easy to do, safe, and didn’t require a lot of time and money. Research related to the effect of Benson's relaxation on student stress levels was also still limited. Objective: To analyze the effect of Benson’s relaxation on stress levels in students of the Faculty of Medicine Diponegoro University who were working on a thesis. Methods: Quasi-experimental study with pre-test and post-test design. This research involved 64 final-year medical students and divided into two groups. A consecutive sampling technique was performed. The experimental group (n=32) were instructed to do Benson’s relaxation therapy for 14 days, each day 2 session for 10 minutes, and the control group were instructed to not do any exercise and other relaxation. The stress levels was measured with the Perceived Stress Scale (PSS). Data’s significance was analyzed with paired sample T-test and independent sample T-test. Results: A significant decrease (p<0,001) in stress level before and after Benson relaxation, from 16,34 ± 6,91 to 11,31 ± 4,79. The post-test stress level of the experimental group (11,31 ± 4,79) was significantly (p=0,001) lower than the control group (16,09 ± 5,79). Meanwhile, there were no significant differences on the pre-test stress level between two groups (p=0,781). Conclusion: Benson’s relaxation reduced stress levels in students of the Faculty of Medicine Diponegoro University who were working on a thesis.
Manajemen Nyeri Non-Farmakologis dalam Mengurangi Nyeri pada Pasien HIV/AIDS: Scoping Review Pratiwi, Annisa; Sujianto, Untung; Muniroh, Muflihatul
Jurnal Keperawatan Vol 16 No 3 (2024): Jurnal Keperawatan: September 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32583/keperawatan.v16i3.1868

Abstract

Permasalahan fisik yang paling sering dilaporkan penderita HIV/AIDS adalah nyeri. Dampak dari nyeri yaitu dapat mengganggu aktivitas, pola tidur, pekerjaan, suasana hati, dan menyebabkan penurunan kualitas hidup. Manajemen nyeri non-farmakologis dapat mengurangi nyeri, meningkatkan penyesuaian dan membuat pasien percaya bahwa pasien dapat mengendalikan rasa sakit. Tujuan dari scoping review ini adalah mengetahui manajemen nyeri non-farmakologis yang digunakan untuk mengurangi nyeri pada pasien HIV/AIDS. Metode: Sumber literatur diperoleh melalui pencarian dengan menggunakan database PubMed, Scopus, Sciencedirect, Proquest, dan Google Scholar. Kata kunci yang digunakan dalam pencarian yaitu HIV/AIDS, manajemen non farmakologi, dan nyeri. Persamaan pencarian diterapkan tanpa batasan, dengan mempertimbangkan judul, abstrak, intervensi, dan metode yang digunakan. Artikel yang telah didapatkan selanjutnya dianalisis perbedaan serta adanya duplikasi. Bagan untuk representasi visual tentang bagaimana pencarian dan pemilihan artikel dibuat PRISMA-SR flow diagram. Ekstraksi data dilakukan dengan membuat tabel. Hasil: manajemen nyeri non-farmakologis yang dapat dilakukan pada pasien HIV/AIDS yaitu perawatan profesional non-farmakologi (pijat, akupuntur/akupresur, terapi fisik, stimulator tulang belakang, kiropraktik, biofeedback dengan provider), mind-body treatment (latihan/exercise, meditasi, yoga), perawatan mandiri non-farmakologis (biofeedback, stimulasi saraf elektrik transkutan/TENS, hot/cold, gosok/pijat titik tubuh), hipnosis, latihan dan pendidikan dengan metode peer-led, pendidikan nyeri, dan terapi fisik. Simpulan penelitian ini adalah Manajemen nyeri non-farmakologis tersebut dapat menurunkan nyeri, meningkatkan kualitas hidup, dan mendukung pemulihan pasien HIV/AIDS secara holistik.
Dietary inflammatory index, physical activity, body composition, and high sensitivity c-reactive protein levels in adolescent athletes in Central Java Widyastuti, Trioni; Susanto, Hardhono; Noer, Etika Ratna; Muniroh, Muflihatul; Widyastiti, Nyoman Suci
Jurnal Keolahragaan Vol 12, No 2: September 2024
Publisher : Program Studi Ilmu Keolahragaan Program Pascasarjana Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21831/jk.v12i2.73072

Abstract

Inflammation is the body's response to tissue damage and infection. Prolonged inflammation can increase the risk of non-communicable diseases, including cardiovascular disease. Some factors that can trigger inflammation are dietary patterns, high physical activity, and body composition. This study examined the correlation between dietary inflammatory index (DII), physical activity, body composition, and high sensitivity C-reactive protein (hs-CRP) levels. It examined differences in characteristics based on gender. This study was a cross-sectional design of 55 adolescent athletes at the Student Sports Education and Training Center in Central Java. The exclusion criteria were an athlete who had a physical injury (did not participate in training) and a smoker. The DII score was calculated based on the dietary pattern using SQFFQ, anthropometric data (weight, height, and nutritional status based on BMI/age), body composition (body fat percentage, fat mass, and fat-free mass) using the BIA tool, physical activity data for the last seven days using IPAQ and hs-CRP levels using the FIA method. Our result showed that the DII score was significantly correlated with hs-CRP (p=0.013). There was no correlation between physical activity, body composition, and anthropometry with hs-CRP levels (p0.05). There were differences in body height, body weight, body fat percentage, and fat-free mass between males and females (p0.001). The diet of athletes had anti-inflammatory potential (83.6%), as evidenced by the intake of vitamins and minerals, and athletes had low hs-CRP levels 1 mg/L (85.5%), indicating that no inflammation occurred. Future longitudinal research is needed with a large population of adolescent athletes to explain the role of anti-inflammatory and pro-inflammatory diets on the incidence of inflammation and measure physical exercise in athletes to reduce inflammatory bias.
Determinant factors of obesity in urban and rural studies on adolescents in Banten Province, Indonesia Perdanawati, Mia; Nugraheni, Sri Achadi; Syauqy, Ahmad; Noer, Etika Ratna; Muniroh, Muflihatul
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 12, No 2 (2024): June
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.12.2.126-135

Abstract

Background: The prevalence of obesity which continues to grow in children and adolescents is a concern since it increases degenerative disease risk. Obesity is not only a problem in urban areas, but it is also growing in rural areas.Objective: The aim of this study was to analyze the determinants of obesity in adolescents in rural and urban areas in Banten Province.Materials and Methods: This research design used a case-control method with a purposive sampling technique. The sample in the study consisted of 160 adolescent subjects from 2 different schools. Each school representing 40 case samples that were adolescents with obesity and control adolescents with a normal body mass index. This study was conducted at one school in Cilegon City to represent the urban sample and one school in Pandeglang Regency to represent the rural sample. For each sample, body weight and height were measured, filling out the SQ-FFQ, International Physical Activity Questioner (IPAQ), Pittsburgh Sleep Quality Index and DASS-42 (Depression Anxiety Stress Scale) questionnaires. Data regarding the results of air quality monitoring which includes data (PM10, SO2 O3 and NO2) was obtained from the Environmental Service. Meanwhile, data were analyzed by using Chi-Square and logistic regression.Results: The determinants of obesity in adolescents in rural were protein intake more than RDA (p=0.003 OR=9.948), low physical activity (P=0.005 OR=22.094), high of  SO2 exposure (P=0.005 OR=19.817) and bad sleep quality (P=0.007 OR=8.901) while adolescents in urban were protein intake more than RDA  (p=0.001 OR=21.570), bad sleep quality (p=0.002 OR=16.550), high stress level (p=0.006 OR=15.922) and carbohydrate intake more than RDA  (p=0.072 OR=5.044).Conclusion: Protein intake is the biggest determinant of the incidence of obesity in adolescents both in rural and urban areas.
Co-Authors - Anggorowati Adriyan Pramono Afriana, Rizky Dyas Ahmad Syauqy Anjani, Gemala Annastasia Ediati Annisa Pratiwi, Annisa Ardyarini, Hikmatunnisa Tri Ariani, Mahayu D. Ariosta Ariosta Awal Prasetyo Besari Adi Pramono Bintang, Francisca Natalia Diana Nur Afifah, Diana Nur Djuara P Lubis Elsa Naviati Endang Sri Lestari Etika Ratna Noer Hadiprajitno, Peter I. Hardhono Susanto Hermawan Istiadi Julian Dewantiningrum Juniarto, Achmad Z. Karlowee, Vega Kesuma, Erlangga Hadi Kesumayadi, Irfan Kis Djamiatun Mambaya, Helvi Desi Mohammad Sulchan Muhammad Nur Nani Maharani Natalia Dewi Wardani Nugraha, Eka Djatnika Nyoman Suci Widyastiti Partiwi, Rina Perdanawati, Mia Qolby, Qonita Nur Renni Yuniati Retnoningrum, Dwi Septiani, Bernadeta Novita Sri Achadi Nugraheni Untung Sujianto Utami, Arini Veni, Rizka Widyastuti, Trioni Yetty Movieta Nency, Yetty Movieta Yora Nindita Yosef Purwoko Zetta, Adelia Paradya