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All Journal AcTion: Aceh Nutrition Journal Jurnal Kedokteran dan Kesehatan Alami Journal (Alauddin Islamic Medical) Journal Al-sihah: The Public Health Science Journal Celebes Health Journal Jurnal Kedokteran: Media Informasi Ilmu Kedokteran dan Kesehatan Jurnal Ners Jurnal Life Birth Jurnal Comprehensive Health Care Jurnal Integrasi Kesehatan dan Sains Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran JOURNAL LA MEDIHEALTICO Jurnal Multidisiplin Madani (MUDIMA) Journal of Community Health Provision Innovative: Journal Of Social Science Research Jurnal Pengabdian Ilmu Kesehatan
Arlina Wiyata Gama
Universitas Islam Negeri Alauddin Makassar
Humanities Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Protective effect of Diadema setosum gonad extract against oxidative stress in D-Galactose-induced aging rats Gama, Arlina Wiyata; As'ad, Suryani; Alam, Gemini; Eragradini, Athirah Rinandha
AcTion: Aceh Nutrition Journal Vol 10, No 4 (2025): December
Publisher : Department of Nutrition at the Health Polytechnic of Aceh, Ministry of Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/action.v10i4.2832

Abstract

Oxidative stress is a primary mechanism of aging and is characterized by elevated levels of malondialdehyde (MDA). Natural antioxidants are being increasingly explored for the prevention of premature aging. The gonads of the sea urchin Diadema setosum contain bioactive compounds, including omega-3 fatty acids, flavonoids, and phenolics, which possess unique ecological adaptations that enhance secondary metabolite production, making them a promising marine antioxidant source. This study aimed to evaluate the effect of D. setosum gonad extract on MDA levels in male Wistar rats undergoing d-galactose-induced aging. An experimental post-test control group design was conducted from July to November 2024, involving 24 rats divided into four groups: standard control (K1), positive control (K2), and two treatment groups receiving extracts at doses of 100 mg/kg (P1) and 300 mg/kg (P2). D-galactose was used for aging at 150 mg/kg body weight for eight weeks, followed by oral administration of the extract for an additional eight weeks. MDA levels were measured using ELISA at weeks 0, 6, 10, and 14. The results showed a significant increase in MDA levels in the positive control group (K2) compared to the normal group (p=0.002), indicating oxidative stress induction. In contrast, treatment with D. setosum gonad extract, particularly in the P2 group, significantly reduced MDA levels (p<0.05), approaching those of the normal group. In conclusion, D. setosum gonad extract has potential as a natural antioxidant for suppressing oxidative stress associated with aging.
Peningkatan Literasi Kesehatan Ibu Melalui Edukasi Imunisasi Dasar Anak di Wilayah Puskesmas Bontomarannu, Kabupaten Gowa Indirah Maudy Miftahul Jannah; Arlina Wiyata Gama; Najamuddin Najamuddin; Rista Suryaningsih; Arifuddin Ahmad
Jurnal Pengabdian Ilmu Kesehatan Vol. 5 No. 1 (2025): Maret : Jurnal Pengabdian Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v5i1.4995

Abstract

: Incomplete immunization can cause morbidity and death due to diseases that should be prevented by immunization (PD3I). This study explores the correlation between maternal health literacy and compliance with basic immunization for children aged 0-11 months in Bontomarannu Community Health Center, Gowa Regency. This study design used a retrospective cross-sectional study for quantitative analysis with a total sample of 87 mothers. Research data was obtained from the results of filling out the HLS–EU–Q16 questionnaire and secondary data related to the completeness of child immunization. Research data was analyzed using the Chi Square test with the help of the SPSS program. The results of the analysis show that there is a significant relationship between health literacy and maternal compliance in providing basic immunizations to children (p-value = 0.000). Mothers with adequate health literacy tend to have high compliance in providing children with basic immunizations. The results of the analysis showed that of the 87 mothers studied, the majority of mothers with inadequate health literacy tended to be incomplete in providing basic immunizations to their children, while of all mothers with adequate health literacy, all provided complete basic immunizations. In conclusion, addressing health literacy is crucial for effective immunization programs.
Hubungan Kualitas Tidur dengan Risiko Diabetes Melitus Tipe 2 Pada Remaja Jurusan Tata Boga di Smkn 4 Makassar Aulia Aprilia Awaluddin; Arlina Wiyata Gama; Jelita Inayah Sari; Saharuddin Saharuddin; Rahmi Damis
Jurnal Ners Vol. 10 No. 2 (2026): APRIL 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i2.55597

Abstract

Studi ini dimaksudkan untuk menelaah kaitan kualitas tidur yang rendah terhadap risiko diabetes mellitus tipe 2 pada remaja jurusan Tata Boga di SMKN 4 Makassar. Model riset mengaplikasikan analitik observasional melalui pendekatan cross-sectional. Aspek kualitas tidur dinilai memakai Pittsburgh Sleep Quality Index (PSQI) serta diklasifikasikan menjadi buruk dan baik. Risiko diabetes mellitus dinilai melalui hasil pemeriksaan glukosa darah puasa menggunakan glukometer, kemudian dikelompokkan menjadi tidak berisiko dan berisiko. Jumlah responden sebanyak 136 remaja. Hasil analisis univariat menunjukkan dominasi partisipan mempunyai kualitas tidur yang buruk (84,6%) serta melebihi separuh partisipan terindikasi berisiko diabetes mellitus (51,5%). Pada analisis bivariat, uji Chi-Square mengindikasikan adanya korelasi bermakna antara kualitas tidur dan risiko diabetes mellitus (p = <0,001). Partisipan dengan kualitas tidur yang rendah mencatat tingkat risiko yang lebih tinggi (58,3%) daripada partisipan dengan kualitas tidur yang bagus (14,3%). Bukti ini menguatkan yakni gangguan kualitas tidur pada remaja berkaitan dengan meningkatnya kerentanan risiko gangguan metabolik, sehingga promosi kesehatan tidur dan skrining faktor risiko metabolik sejak usia sekolah penting untuk diperkuat.
Co-Authors Abd Rahman Abdul Rahman Ahmad M Sewang Akib, Rahmawati Aliah, Andita Fitri Alifia Ayu Delima Andi Irhamnia Sakinah Andi Irhamniah Sakinah Andi Nurul Hidaya Azzahara Arief Santoso Arifuddin Ahmad Armin, Ilma Aminah Arsy, Andi Muhammad Fadhyl As'ad, Suryani Asri, Amanda Asriani Asriani Aulia Aprilia Awaluddin Azizah Nurdin Azizah Nurdin, Azizah Azizul Hakim Darmawansyih Deviana, Deviana Dewi Meliyani Ramadlana Suleman Dewi Setiawati Eragradini, Athirah Rinandha Gemini Alam Henny Fauziah Idris, Irfan Ika Yustisia Indirah Maudy Miftahul Jannah Intan Nursiani Isra Wahid Jelita Inayah Sari Jumriani Jum Khaera, Ummul Larasati, Iip Muftia Jauristika Sarifuddin Muh. Akhdan Falih Yusuf Mukhlis Mukhtar Mukhtar Lutfi Mulkiyah Zul Fadhilah Musafir Pababbari Najamuddin Andi Palancoi Najdwah Emilia Nur Alifka Riska Amalia Nurpudji A. Taslim Nurul Fatwa S Purnamaniswaty Yunus Purnamaniswaty, Purnamaniswaty Rahadi Arie Hartoko Rahim, Isnada Rahmi Damis Rauly Rahmadhani Rini Fitriani Rini Fitriani Rini Fitriani Rista Suryaningsih Sabry, Muhammad Sadik Saharuddin Saharuddin Sitti Aisyah Kara Tihardimanto, Andi Trisnawaty Ulfah Rimayanti Zulfahmi Alwi