Article Per Year (5 Year)
p-Index From 2021 - 2026
4.221
P-Index
This Author published in this journals
All Journal Indonesian Journal of Pharmaceutical Science and Technology Jurnal Agroindustri Biology, Medicine, & Natural Product Chemistry Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Penelitian Pendidikan IPA (JPPIPA) Window of Health : Jurnal Kesehatan Media Farmasi PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Journal of Pharmaceutical and Medicinal Sciences Fullerene Journal of Chemistry Jurnal Ilmiah Farmasi Farmasyifa ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal farmasi UIN Alauddin Makassar Jurnal Mandala Pengabdian Masyarakat Yumary: Jurnal Pengabdian kepada Masyarakat Narra J Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pengabdian Kefarmasian jpki Jurnal Katalisator Media Farmasi Jurnal Tumbuhan Obat Indonesia Media Penelitian dan Pengembangan Kesehatan Jurnal Sains dan Kesehatan
Khairi, Nur
Fakultas Ilmu Kesehatan Universitas Almarisah Madani
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

Published : 27 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Biology, Medicine,

 1 
Development and Evaluation of a Stable Topical Cream Formulated with Annona squamosa Seed Extract as a Natural Pediculosis Agent Khairi, Nur; Muslimin, Lukman; Mubarak, Fhahri; Indrisari, Maulita; Fajriansyah, Fajriansyah
Biology, Medicine, & Natural Product Chemistry Vol 14, No 2 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.142.1355-1363

Abstract

Head lice infestation (Pediculosis capitis) remains a global public health concern, exacerbated by growing resistance to conventional pediculicides such as permethrin and malathion. This study aimed to evaluate the pediculicidal activity and formulation stability of a topical cream containing Annona squamosa (sugar apple or srikaya) seed extract as a natural alternative for treating pediculosis. The ethanolic extract of A. squamosa seeds was obtained through maceration, producing a 10.005% yield. Pediculicidal assays were conducted using various extract concentrations (5%, 7.5%, and 10%), followed by formulation of oil-in-water creams with extract concentrations of 7.5%, 10%, and 12.5%. Physical stability tests included assessments of viscosity, pH, spreadability, adhesion, and homogeneity. Results showed a dose–response relationship, with lice mortality increasing from 60% at 5% extract to 87% at 10%. Extract. The formulated creams demonstrated high efficacy—86% to 96% mortality—comparable to 1% permethrin. All formulations maintained acceptable physicochemical properties (pH 4.8–5.5, viscosity within 27,000–47,000 cps) and remained stable after accelerated storage. These findings indicate that A. squamosa seed extract is a potent pediculicidal agent that can be effectively incorporated into a stable topical formulation. The study supports the potential of A. squamosa as a safe, sustainable, and plant-based alternative for managing pediculosis while addressing the challenge of chemical resistance.
Co-Authors Abdul Halim Umar Agustina Ma'tang Parinding Aisyah , Andi Nur Aisyah, Andi Nur Akbar Awaluddin Aksa, Rahmat Alexandra, Francisca Diana Ali Djamhuri Amriani Amriani Amriani Sapra Amriani Sapra Andi Nur Aisyah Andi Nur Aisyah Andi Nur Aisyah, Andi Nur Aisyah Andi Paluseri Andi Paluseri Anggyasti, Anggyasti Arisah, Arisah Astuti Amin Awaluddin, Akbar Burhan, Asril Dali Djamaluddin, Suci F Dwirandy, Dwirandy Eko Allo Fadillah Maryam Fajriansyah Fajriansyah Fhahri Mubarak Fitriyanti Jumaetri Hapiwaty, Saldi Harlyanti Muthma'innah Mashar Ikbal Ikbal Ikbal Indradewa, Rhian Irwana, Rina Ismail Ismail Ismail Jumarni Jumarni Khairuddin Khairuddin Lukman Lukman Lukman Muslimin Madinatul munawwarah Malluka, Rifka Margaretha Margaretha Maria Ulfa Maria Ulfa Maria Ulfa Marwati Marwati Marwati Marwati Marwati Marwati Mar’atun Jannah, Imrawati, Muzakkir Baitz, Maulita Indrisari Maulita Indrisari, Maulita Megawati - Megawati Megawati Michrun Nisa Mirnawati Salampe Mus, Suwahyuni Muslimin, Lukman Noer Fauziah Nursamsiar Nursamsiar Nurul fadillah, Nurul Nurul Hikma Nurwijayanti Nurzadrina Wahyuddin paluseri, Andi Reny Syahruni Riska Rahayu Rosyid, Sujud Z Sami, Fitriyanti Sapra, Amriani Sepriani Yusuf Sitti Rahimah, Sitti Solly Aryza Sukmawati Sukmawati Sukriani Kursia, Sukriani Suryani Tawali Suwahyuni Suwahyuni Syamsu Nur Syamsu Nur Syamsu Nur, Syamsu Syamsu Nur, Syamsu Nur Utami, Novi F. Wahyu Hendrarti Wahyu Hendrarti Wahyu Hendrarti Yuri Pratiwi Utami Zulham, Zulham