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All Journal Jurnal Fitofarmaka Indonesia Journal of Islamic Medicine Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Medika Malahayati Jurnal Mandala Pharmacon Indonesia JFM (Jurnal Farmasi Malahayati) Jurnal Pengabdian Farmasi Malahayati (JPFM) Jurnal Analis Farmasi Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmiah Wahana Pendidikan JAF (Jurnal Analis Farmasi) Indonesian Journal of Biological Pharmacy Jurnal Multidisiplin Dehasen (MUDE) JURNAL PENELITIAN TERAPAN KESEHATAN JOURNAL OF Pharmacy and Tropical Issues
Ulfa, Ade Maria
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Uji Aktivitas Kombinasi Ekstrak Daun Binahong (Anredera cordifolia (Ten.) Steenis) Dan Kulit Jeruk Nipis (Citrus aurantifolia) Terhadap Penyembuhan Luka Sayat Saputri, Naila; Nofita, Nofita; Ulfa, Ade Maria
Jurnal Ilmiah Wahana Pendidikan Vol 10 No 9 (2024): Jurnal Ilmiah Wahana Pendidikan
Publisher : Peneliti.net

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.11180260

Abstract

Plants that are efficacious as wound healers from natural ingredients, namely binahong leaves and lime peel. This study aims to determine the effectiveness of the combination of binahong leaf extract (Anredera cordifolia (Ten.) Steenis) and lime peel (Citrus aurantifolia) on the healing of cuts in male rats (Rattus noervegicus). In the test animal, an incision was made on the back with a length of 2 cm and a wound depth of 0.2 cm using a scalpel (bisturi). The test animals were divided into six treatment groups: normal control without ointment, negative control given ointment base, positive control given povidone iodine ointment, formulation 1 given extract combination ointment (1:3), formulation 2 given extract combination ointment (1:1). , and formulation 3 was given an extract combination ointment (3:1). Ointment is given twice daily for 14 days. Observation of wound healing was carried out by measuring the decrease in the length of the incision in the test animals. The results showed that the combination ointment of binahong leaf extract and lime peel formulation 1 with concentration (1:3) and formulation 2 with concentration (1:1) experienced healing on the 8th day, formulation 3 with concentration (3:1) experienced recovery on day 9. Statistical results using the Mann Whitney HocPost for the F1, F2, and F3 treatment groups compared to the positive control did not have a significant difference because the value obtained was p> 0.05. It was concluded that the combination ointment of binahong leaf extract and lime peel has healing activity for cuts and can be used as a healer for cuts.
FORMULASI DAN UJI EFEKTIVITAS KELEMBABAN SEDIAAN KRIM M/A EKSTRAK KULIT MANGGIS (Garcinia mangostana L.) Clarista, Helaria Eren; Ulfa, Ade Maria; Nofita, Nofita
JURNAL PENELITIAN TERAPAN KESEHATAN Vol 11 No 2 (2024): JURNAL PENELITIAN TERAPAN KESEHATAN
Publisher : Poltekkes Kemenkes Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33088/jptk.v11i2.877

Abstract

Skin can be said to be moist if it has a water content of 40%. One way to maintain the effectiveness of moisture in the skin is by using moisturizing cosmetics, such as cream. Mangosteen fruit (Garcinia mangostana L.) is a plant that has benefits, especially in its skin. There are compounds that have been proven to provide a moisturizing effect thereby protecting the skin from skin oxidation and free radicals. The purpose of making this cream is to moisturize the skin and utilize mangosteen peel extract. The advantage of cream with the O/W emulsion type is that it does not cause a sticky feeling, is easy to spread on the skin surface, is soft, and is easily washed off with water. Mangosteen peel extract was obtained using the maceration method with 96% ethanol. The cream preparation was made into 4 formulations K0, F1, F2, and F3 based on the amount of mangosteen extract used. Then a Physical Evaluation Test, Irritation Test, Likeability Test and Moisture Test were carried out. Each formulation was tested for moisture using an SK-8 skin analyzer. Evaluation of cream use was carried out by 12 volunteers for 5 days with use during the day. The overall results obtained were that the 3% mangosteen extract F1 formulation met the quality standards for physical cream preparations and had a high increase in water content in the volunteers' skin with a percent water content value of 50.16%. Meanwhile, in the analysis of the Wilcoxon test and Paired T-test data, a significance value of 0.00 (<0.05) was obtained which means that mangosteen peel extract cream can increase moisture in the skin, and variations in extract concentration have an influence on the effectiveness of the cream in moisturizing the skin.
SINTESIS KATALIS CaO DARI CANGKANG TELUR BEBEK UNTUK DEGRADASI TETRASIKLIN DAN ALLURA RED Feronica, Sagita; Ulfa, Ade Maria; Husein, Saddam
JFM (Jurnal Farmasi Malahayati) Vol 8, No 1 (2025)
Publisher : Jurnal Farmasi Malahayati (JFM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jfm.v8i1.17593

Abstract

Proses fotokatalisis ini limbah tetrasiklin dan katalis CaO akan dicampurkan sehingga diharapkan dari proses fotokatalisis ini dapat mendegradasi limbah tetrasiklin dan membuat kontaminan berkurang atau hilang. Hasil yang diperoleh katalis CaO Cangkang telur bebek memiliki intensitas puncak yang cukup tajam yaitu 2θ= 32,23, 37,39, dan 53,93 serta memiliki serapan pada 3 daerah serapan yaitu 721 cmˉˡ, 875 cmˉˡ, dan 1420 cmˉˡ. Larutan simulasi limbah tetrasiklin dengan konsentrasi 50 ppm setelah dilakukan fotokatalisis berubah warna menjadilebih bening. Larutan simulasi limbah merah allura dengan konsentrasi 50 ppm setelah dilakukan fotokatalisis berubah warna menjadi lebih bening. Degradasi yang terjadi selama proses fotokatalisis menurun seiring dengan lamanya durasi penyinaran lampu UV. Kesimpulan penelitian ini adalah Sintesis katalis CaO dari cangkang telur ayam menghasilkan katalis CaO yang mampu berperan mempercepat reaksi dalam proses fotokatalisis terhadap degradasi limbahtetrasiklin dan limbah merah allura.
PENGARUH EDUKASI DAGUSIBU (DAPATKAN, GUNAKAN, SIMPAN DAN BUANG) SEDIAAN OBAT SIRUP ANAK TERHADAP TINGKAT PENGETAHUAN IBU DI LANGKAPURA BANDAR LAMPUNG Ulfa, Ade Maria; Sunowo, Joko; Muliyanti, Reni; Putri, Restika Ananda; Liani, Reza
Jurnal Pengabdian Farmasi Malahayati (JPFM) Vol 7, No 2 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jpfm.v7i2.18238

Abstract

ABSTRACTDagusibu is an educational program established by the Indonesian Pharmacists Association (IAI) related to obtaining, using, storing, and disposing of medicine correctly. The lack of knowledge regarding information on how to manage drugs from getting the medicine until it is no longer consumed and finally disposed of, so that the impact of misuse of syrup in the community can be prevented. This counseling activity was aimed to determine the increase in mother's knowledge about DAGUSIBU for children's syrup preparation before and after counseling in Langkapura Bandar Lampung. The method used was survey method in the form of discussion, interviews, and observation and statistical analysis using paired T test. The results showed an increase in knowledge of mothers who had babies / toddlers about DAGUSIBU children's syrup medicine correctly seen from the average value obtained before counseling amounted to 36.94% and after counseling, namely amounted to 91.11% so that an increase of an increase of 54.17%. Statistical data showed that there was a relationship between providing education with increased knowledge of mothers who have babies / toddlers where the p-value was 0.00 with a confidence level of 95%. Keywords: DAGUSIBU, education, medicine, counseling, syrup. ABSTRAKDagusibu adalah program edukasi yang dibentuk oleh Ikatan Apoteker Indonesia (IAI) terkait dapatkan, gunakan, simpan, dan buang obat dengan benar. Minimnya pengetahuan masyarakat mengenai informasi tentang tata cara pengelolaan obat dari mendapatkan obat hingga sudah tidak dikonsumsi lagi dan akhirnya dibuang, sehingga dampak dari kesalahan penyalahgunaan obat sirup pada masyarakat dapat dicegah. Kegiatan penyuluhan ini bertujuan mengetahui peningkatan pengetahuan Ibu tentang DAGUSIBU sediaan obat sirup anak sebelum dan sesudah penyuluhan di Kelurahan Langkapura Bandar Lampung. Metode yang digunakan  metode survei berupa diskusi, wawancara, dan observasi dan analisis statistik menggunakan uji paired T test. Hasil edukasi didapatkan peningkatan pengetahuan ibu-ibu yang memiliki bayi/balita tentang DAGUSIBU obat sirup anak dengan benar dilihat dari nilai rata-rata yang diperoleh sebelum penyuluhan sebesar 36,94% dan setelah dilakukan penyuluhan yaitu sebesar 91,11%  sehingga diperoleh peningkatan sebesar 54,17 %. Data statistik menunjukkan  ada hubungan antara pemberian edukasi dengan peningkatan pengetahuan ibu-ibu yang memiliki bayi/balita dimana p-value 0,00 dengan taraf kepercyaan 95%. Kata Kunci: DAGUSIBU, edukasi, obat, penyuluhan, sirup
Pengaruh Bentuk Sediaan Kosmetik Ekstrak Etanol Kulit Buah Pepaya (Carica papaya L.) terhadap Stabilitas Fisika dan Kimia Aprilia, Berlian Nindi; Ulfa, Ade Maria; Amalia, Putri
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 2 (2025): Jurnal Mandala Pharmacon Indonesia 
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i2.1061

Abstract

Kulit adalah lapisan terluar tubuh yang berperan melindungi terhadap patogen. Paparan sinar matahari berlebih memicu pembentukan radikal bebas yang merusak integritas kulit. Penelitian bertujuan untuk mengevaluasi pengaruh bentuk sediaan kosmetik (gel dan spray) yang mengandung ekstrak etanol kulit buah pepaya terhadap stabilitas fisika dan kimia. Kulit buah pepaya (Carica papaya L.) dikenal kaya senyawa bioaktif dengan potensi antioksidan. Penelitian dilakukan dengan ekstraksi perkolasi menggunakan pelarut etanol 70% diperoleh rendemen 42,2%. Uji stabilitas dilakukan dengan metode cycling test. Parameter stabilitas fisik meliputi evaluasi organoleptis, homogenitas, pengukuran pH, daya sebar, daya lekat, dan viskositas. Kedua sediaan menunjukkan perubahan variatif namun tetap berada dalam batas stabilitas yang ditentukan sepanjang masa penyimpanan. Metode FRAP (Ferric Reducing Antioxidant Power) digunakan untuk menguji aktivitas antioksidan sebelum dan setelah 12 hari penyimpanan, menunjukkan penurunan signifikan pada kedua sediaan. Analisis data menggunakan SPSS 26.0 dengan uji Repeated Measures ANOVA, Friedman dan Wilcoxon. Hasil diperoleh bahwa bentuk sediaan gel dan spray secara signifikan memengaruhi pH, daya sebar, daya lekat, dan viskositas dengan nilai Sig. <0,05.
SOSIALISASI SERBUK KELOR (MORINGA OLEIFERA) SEBAGAI MAKANAN ALTERNATIF PENGGANTI ZAT BESI UNTUK MENGATASI ANEMIA DI DESA RULUNG SARI, KEC. NATAR LAMPUNG SELATAN Ulfa, Ade Maria; Aprilia, Berlian Nindi; Lestari, Dian; yah, Ina
Jurnal Pengabdian Farmasi Malahayati (JPFM) Vol 8, No 2 (2025)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jpfm.v8i2.19318

Abstract

Anemia adalah suatu kondisi di mana jumlah sel darah merah atau konsentrasi hemoglobin di dalamnya lebih rendah dari normal. Faktor yang paling dominan dalam mempengaruhi kejadian anemia adalah faktor ketidakpatuhan ibu hamil dalam mengkonsumsi tablet zat besi (Fe) dan diikuti faktor asupan nutrisi ibu hamil selama masa kehamilan yang tidak adekuat. Tingkat kepatuhan ibu hamil dalam mengkonsumsi tablet Fe sangat mempengaruhi keadaan anemia pada ibu hamil. Kegiatan pengabdian kepada masyarakat melalui sosialisasi  bertujuan untuk memberikan edukasi guna meningkatkan pengetahuan masyarakat Posyandu Mawar, Dusun II Suka Bandung, Desa Rulung Sari, Kec. Natar Lampung Selatan tentang pemanfaatan serbuk daun kelor (Moringa Oleifera) sebagai makanan alternatif pengganti untuk pencegahan atau mengatasi anemia. Sosialisasi ini menggunakan metode ceramah, demonstrasi, diskusi, dan tanya jawab dengan bantuan brosur dan alat demonstrasi. Hasil pretest dari 30 peserta sosialisasi menunjukan persentase tingkat pengetahuan masyarakat masih rendah 47.3 %, sedangkan tingkat pengetahuan tinggi sebesar 93% pada hasil posttest. Berdasarkan hasil tersebut dapat disimpulkan bahwa pengetahuan dan keterampilan masyarakat Desa Sidodadi tentang pemanfaatan serbuk daun kelor (Moringa Oleifera) sebagai makanan alternatif pengganti untuk pencegahan atau mengatasi anemia meningkat secara signifikan setelah dilakukannya sosialisasi.
UJI EFEKTIVITAS EKSTRAK KULIT JERUK NIPIS (Citrus aurantifolia) TERHADAP BAKTERI Staphylococcus aureus DAN Escherichia coli DALAM SEDIAAN GEL HAND SANITIZER Setiawan, Iwang Davi; Ulfa, Ade Maria; Marcellia, Selvi; Aprianti, Indah; Meithia, Artha; Cahyani, Arta Arum
Jurnal Analis Farmasi Vol 11, No 1 (2026): JURNAL ANALIS FARMASI
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jaf.v11i1.25708

Abstract

Hand sanitizer gel has been commonly used as on of the ways to maintain health and hand sanity which is practical and easy to carry along. One of the plant whichi has an anti-bacteria is lime (Citrus aurantifolia). The purpose of this study was to acknowledge lime peel extract's resistance inside a hand sanitizer gel toinhibit the growth od Staphylococcus aureus dan Escherichia coli. The lime peel extraction used maceration method with 96% ethanol solvent. Bacterial inhibition testing on lime peel extract used by the disk method and on hand sanitizer gel preparations used by the wells method. The concentration of lime peel extract used was 20%, 25%, 30%, 35%, 40% and positive control with an average inhibition zone of 8.91 mm, 10.19 mm, 10.42 mm, 10.67 mm , 11.00 mm, 29.16 mm against Staphylococcus aueurus bacteria and 6.89 mm, 8.39 mm, 9.31 mm, 9.72 mm, 9.97 mm and 24.22 mm against Escherichia coli bacteria. In the preparation of hand gel sanitizer, the concentrations used were 20%, 22%, 25% and positive control with an average inhibition zone of 9.11 mm, 9.42 mm, 10.23 mm, 10.40 mm against Staphylococcus aueurus bacteria and 7.21 mm, 8.11 mm, 8.50 mm and 10.35 mm against Escherichia coli bacteria. The antibacterial test results were analyzed using ANOVA, the results of statistical analysis on lime peel extract and hand sanitizer gel of lime peel extract showed a significant inhibition zone difference 0,000 (P = 0.05) between all concentrations of lime peel extract. Lime peel extract in a hand sanitizer gel was effective in inhibiting the bacteria Staphylococcus aureus and Escherichia coli.
UJI EFEKTIVITAS EKSTRAK KULIT JERUK NIPIS (Citrus aurantifolia) TERHADAP BAKTERI Staphylococcus aureus DAN Escherichia coli DALAM SEDIAAN GEL HAND SANITIZER Setiawan, Iwang Davi; Ulfa, Ade Maria; Marcellia, Selvi; Aprianti, Indah; Meithia, Artha; Cahyani, Arta Arum
Jurnal Analis Farmasi Vol 11, No 1 (2026): JURNAL ANALIS FARMASI
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jaf.v11i1.25708

Abstract

Hand sanitizer gel has been commonly used as on of the ways to maintain health and hand sanity which is practical and easy to carry along. One of the plant whichi has an anti-bacteria is lime (Citrus aurantifolia). The purpose of this study was to acknowledge lime peel extract's resistance inside a hand sanitizer gel toinhibit the growth od Staphylococcus aureus dan Escherichia coli. The lime peel extraction used maceration method with 96% ethanol solvent. Bacterial inhibition testing on lime peel extract used by the disk method and on hand sanitizer gel preparations used by the wells method. The concentration of lime peel extract used was 20%, 25%, 30%, 35%, 40% and positive control with an average inhibition zone of 8.91 mm, 10.19 mm, 10.42 mm, 10.67 mm , 11.00 mm, 29.16 mm against Staphylococcus aueurus bacteria and 6.89 mm, 8.39 mm, 9.31 mm, 9.72 mm, 9.97 mm and 24.22 mm against Escherichia coli bacteria. In the preparation of hand gel sanitizer, the concentrations used were 20%, 22%, 25% and positive control with an average inhibition zone of 9.11 mm, 9.42 mm, 10.23 mm, 10.40 mm against Staphylococcus aueurus bacteria and 7.21 mm, 8.11 mm, 8.50 mm and 10.35 mm against Escherichia coli bacteria. The antibacterial test results were analyzed using ANOVA, the results of statistical analysis on lime peel extract and hand sanitizer gel of lime peel extract showed a significant inhibition zone difference 0,000 (P = 0.05) between all concentrations of lime peel extract. Lime peel extract in a hand sanitizer gel was effective in inhibiting the bacteria Staphylococcus aureus and Escherichia coli.
Co-Authors Ajimahtinur, Selma Alfi Lestari, Alfi Aprianti, Indah Aprila, Nur Amalia Aprilia, Berlian Nindi Asih, Putri Audia, Abel Mia Awalliyyah, Wahid Datul Br Barus, Emia Athena Cahyani, Arta Arum Clarista, Helaria Eren Desbrianto, David DIAN LESTARI Dwi Susanti Elsyana, Vida Eti Rahmawati Fadhil, Rafi Muhammad Fernanda, Nia Feronica, Sagita Fitriyanti, Desi Hidayaturahmah, Rizky Isliana, Sindi Joko Sunowo, Joko khusnul khotimah Lestari, Yovita Endah Liani, Reza Lysti, Erna Marcellia, Selvi Mariza, Ana Maulana, Difa Aryan Meithia, Artha Melita, Dina Ayu Muhammad Rudy Muliyanti, Reni Mulyani, Tarifa Ananda Nasution, Yolanda Nirmala, Pramesti Syifa Nofita, Nofita Nur Thahira, Alya Putri Nuryanto, Bayu Pratama, Rendiko Agung Candra Putri Amalia Putri, Anzela Andandya Putri, Bella Rimbun Putri, Restika Ananda Putri, Saskia Diska Rinatha, Elsha Robby Candra Roni, Rasikha Khairunnisa Saddam Husein Saputri, Gusti Ayu Rai Saputri, Naila Saputri, Nurotul Mega Sari, Rizki Tribuana Selvi Marcellia Setiawan, Iwang Davi Shinta Wulandari, Shinta Sinaga, Agnes Santa Sylvia Suhanawati, Tenti Sunarsih Sunarsih Tamarin, Laura Triaisya, Kayla Triyola, Agnes Tutik Tutik Utami, Dimar Putri Wachyuni, Mhella Nia Wahyuni, Anis Wardhani, Aulia Gita Winahyu, Diah Astika yah, Ina Yasmin, Adinda Nurina