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All Journal Medula Indonesian Journal of Urology JURNAL PENELITIAN PERAWAT PROFESIONAL Indonesian Journal of Electrical Engineering and Computer Science JK Unila (Jurnal Kedokteran Universitas Lampung) Indonesian Journal of Nursing and Health Sciences (IJNHS) Jurnal Ilmiah STIKES Yarsi Mataram JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai
Hadibrata, Exsa
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Agriculture, Biological Sciences & Forestry Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Pengaruh Peer Education Terhadap Perilaku Breast Self Examination (BSE) pada Wanita Usia Subur suharmanto, suharmanto; Hadibrata, Exsa
Jurnal Ilmiah STIKES Yarsi Mataram Vol. 15 No. 1 (2025): Jurnal Ilmiah STIKES Yarsi Mataram
Publisher : Sekolah Tinggi Ilmu Kesehatan YARSI Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57267/jisym.v15i1.431

Abstract

The incidence of breast cancer in Indonesia is increasing which can be detected as a preventive effort with breast self-examination. The purpose of this study was to analyze the effect of peer education on breast self-examination behavior. This study used a pre-experimental method, involving 87 people each in the intervention and control groups. Data collection tools used questionnaires and checklist sheets. The results of the study showed that most respondents experienced an increase in knowledge, attitudes, and skills in conducting BSE, so it is hoped that the community can increase their knowledge by reading books, attending seminars, counseling, and training related to breast cancer prevention. ABSTRAK Insidensi kanker payudara di Indonesia meningkat yang dapat dideteksi sebagai upaya pencegahan dengan breast  self  examination. Tujuan penelitian ini adalah menganalisis pengaruh peer education terhadap perilaku breast  self  examination. Penelitian ini  menggunakan metode pra- eksperimen, melibatkan masing-masing 87 orang kelompok intervensi dan kontrol. Alat pengumpul data menggunakan kuesioner dan lembar ceklist. Hasil penelitian menunjukkan bahwa sebagian besar responden mengalami peningkatan pengetahuan, sikap dan keterampilan dalam melakukan BSE, sehingga diharapkan kepada masyarakat agar dapat meningkatkan pengetahuannya dengan cara membaca buku, mengikuti seminar, penyuluhan dan pelatihan terkait pencegahan kanker payudara
Health Belief Model Application Related to Safe Work Behavior Against Poisoning Prevention in Farmers Using Pesticides suharmanto, suharmanto; Hadibrata, Exsa; Wintoko, Risal
Jurnal Ilmiah STIKES Yarsi Mataram Vol. 15 No. 1 (2025): Jurnal Ilmiah STIKES Yarsi Mataram
Publisher : Sekolah Tinggi Ilmu Kesehatan YARSI Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57267/jisym.v15i1.432

Abstract

The World Health Organization estimates that pesticide poisoning occurs yearly in the world and Indonesia. This study aimed to analyze the influence of the Health Belief Model related to safe work behavior on the prevention of poisoning in farmers who use pesticides. This type of research is observational analytic, with a sample of 400 people. The data collection tool used a questionnaire. Data processing includes coding, tabulating, and cleaning. Data analysis used univariate (percentage) and bivariate using the Chi-Square test. The study found a relationship between the dimensions of the Health Belief Model related to safe work behavior on preventing poisoning in farmers who use pesticides. The conclusion of this study is that there is a relationship between the dimensions of the Health Belief Model and the prevention of poisoning in farmers who use pesticides, so it is hoped that the community can increase their knowledge by reading books, attending seminars, counseling and training related to the prevention of poisoning due to the use of pesticides. ABSTRAK World Health Organization memperkirakan setiap tahun terjadi keracunan pestisida di dunia dan Indonesia. Tujuan penelitian ini adalah menganalisis pengaruh Health Belief Model terkait perilaku kerja aman terhadap pencegahan keracunan pada petani pengguna pestisida. Jenis penelitian ini observasional analitik, dengan sampel 400 orang. Alat pengumpul data menggunakan kuesioner. Pengolahan data meliputi coding, tabulating dan cleaning. Analisis data menggunakan univariat (persentase) dan bivariat menggunakan uji Chi-Square. Penelitian mendapatkan adanya hubungan dimensi Health Belief Model terkait perilaku kerja aman terhadap pencegahan keracunan pada petani pengguna pestisida. Simpulan penelitian ini adalah ada hubungan antara dimensi Health Belief Model dengan pencegahan keracunan pada petani pengguna pestisida, sehingga diharapkan kepada masyarakat agar dapat meningkatkan pengetahuannya dengan cara membaca buku, mengikuti seminar, penyuluhan dan pelatihan terkait pencegahan keracunan akibat penggunaan pestisida.
PENGARUH PEMBERIAN EKSTRAK LADA HITAM (Piper nigrum L) TERHADAP LIBIDO (PERILAKU SEKSUAL) MODEL TIKUS PUTIH JANTAN (RATTUS NORVEGICUS) DIABETES MELITUS Isvari, Gusti Ayu Made Prathita; Hadibrata, Exsa; Yunianto, Andi Eka; Susianti
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1284

Abstract

Abstract Diabetes Mellitus causes complications in the form of sexual libido dysfunction. Some of the treatment for libido dysfunction was aphrodisiac (piperin) which consist in black pepper. This study aimed to determine the effect of black pepper (piper nigrum l) extract on male white rat (Rattus norvegicus) libido (sexual behavior) with diabetes mellitus. The study was an experimental laboratory with a post-test only control group design using 30 samples of male white rats (Rattus norvegicus) which divided into 5 groups. Each divided into, control group 1 (K1) consist of normal rats; control group 2 (K2), diabetic rats induced by alloxan 150 mg/kg; treatment group 1 (P1), diabetic rats induced by alloxan 150 mg/kg and given black pepper extract 122.5 mg/kg; treatment group 2 (P2), diabetic rats induced by alloxan 150 mg/kg and given black pepper extract 245 mg/kg; treatment group 3 (P3), diabetic rats induced by alloxan 150mg/kg and given sildenafil 1mg/kg. Libido’s measurement was done by observing intromission latency in second, mount latency in second, mount frequency by its quantity. Kruskal-Wallis test was used to analyzed introducing  latency, whereas mounting latency and mounting frequency was analyzed with One Way ANOVA.  The results showed that introducing latency of group P1 and P2 significantly different compared to group K2 (p=0,003, p=0,003), Mounting latency of group P1 significantly different compared to group K2 (p=0,000) and mounting frequency of group P1 and P2 significantly different compared to group K2 (p=0,000,p=0,006). Black pepper extract enhances male white rat (Rattus norvegicus) libido with diabetes mellitus.
Potensi Lada Hitam Sebagai Obat Herbal Terstandar Untuk Disfungsi Ereksi: Literature Review Hasbullah, Faza; Hadibrata, Exsa; Mayasari, Diana
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1390

Abstract

Erectile dysfunction (ED) is a condition that affects men of all ages and backgrounds, characterized by the inability to achieve or maintain an erection sufficient for sexual intercourse. First-line treatments for ED, such as Phosphodiesterase-5 Inhibitors (PDE5i), often cause side effects and pose contraindications, especially for patients with cardiovascular diseases. Consequently, various studies have been conducted to explore safer natural remedies. One natural substance proven to enhance erectile function is black pepper. This study implement a literature review approach, examining articles from scientific databases published between 2011 and 2025. Piperine, the active compound in black pepper, exhibits significant antioxidant and anti-inflammatory effects, reduces TNF-α levels, and protects nitric oxide (NO) from free radicals. Piperine also enhances testosterone levels by stimulating Leydig cells, contributing to improved erectile function. Moreover, piperine has been shown to increase the expression of the StAR gene, which plays a critical role in testosterone biosynthesis, essential for the erection process. Studies on animal models demonstrated improvements in sexual behavior, testosterone levels, and total penile reflex following black pepper extract administration. Black pepper holds potential as a natural therapy for ED through mechanisms involving increased NO activity, modulation of testosterone hormones, and protection of Leydig cells. While results from animal studies are promising, further research on humans is required to confirm its efficacy and safety.
EFFECT OF RED GINGER (Zingiber officinale Rosc. Var Rubrum) ETHANOL EXTRACT OR SILDENAFIL IN LIBIDO: A COMPARATIVE STUDY USING MALE WHITE RATS (Rattus norvegicus) MODEL WITH DIABETES MELLITUS Hadibrata, Exsa; Sutyarso; Busman, Hendri; Ramdini, Dwi Aulia
Indonesian Journal of Urology Vol 32 No 3 (2025)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v32i3.949

Abstract

Objective: To compare the effect of red ginger ethanol extract and Sildenafil on increasing the libido of diabetic rat models and determine the dose that significantly affects the increase in libido of diabetic rat models. Materials & Methods: This study is an experimental was conducted on 30 male Sprague dawley white rats divided into 6 groups, namely normal control group, negative control group, sildenafil positive control group, 200 mg ginger group, 400 mg ginger group and 600 mg ginger groupstudy consisting of test animal groups: normal control group; negative control; positive control with sildenafil administration, and treatment groups consisting of: dose I (200mg/kgBB); dose II (400mg/kgBB) and, dose III (600mg/kgBB). All groups except the normal control received alloxan induction at the initial stage of testing. The effect of increasing the libido of rats is seen from sexual activity including: latency of copulation, latency of riding (climbing) and frequency of riding. Results: The results of this study indicate that the administration of red ginger ethanol extract at a dose of 400mg/kgBB or 600mg/kgBB has the same potential as sildenafil in increasing the libido of diabetic rat models. Conclusion: The administration of red ginger ethanol extract at a dose of 400mg/kgBB or 600mg/kgBB has the same potential as sildenafil in increasing the libido of diabetic rat models. Keywords: Red ginger, libido, diabetic rat models.
Analisis Fungsi Ereksi pada Tikus Jantan Model Hiperglikemia yang Diinduksi Aloksan Setelah Pemberian Ekstrak Lada Hitam (Piper Nigrum L.) Hadibrata, Exsa; Suharmanto, Suharmanto
Indonesian Journal of Nursing and Health Sciences Vol 6 No 2 (2025): Indonesian Journal of Nursing and Health Sciences: October 2025
Publisher : CV. Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijnhs.v6i2.7374

Abstract

Disfungsi ereksi pada pria hiperglikemia sering kali disebabkan oleh perubahan mikrovaskuler, neuropati, dan disfungsi endotel. Kondisi ini dapat diatasi dengan pemberian ekstrak lada hitam (Piper nigrum L.). Tujuan penelitian ini untuk menganalisis fungsi ereksi pada tikus jantan model hiperglikemia yang diinduksi aloksan setelah pemberian ekstrak lada hitam (Piper nigrum L.). Penelitian ini merupakan penelitian eksperimen, yang dilakukan di Laboratorium Biokimia dan Biomolekuler Fakultas Kedokteran Universitas Lampung bulan Juli-Agustus 2025. Penelitian ini menggunakan tikus putih jantan Rattus norvegicus galur Sprague Dawley sebagai subjek uji, sebanyak 6 ekor dan 5 kelompok (30 ekor). Perlakuan pemberian ekstrak diberikan setiap hari selama 8 hari pada seluruh kelompok. Penentuan dosis ekstrak lada hitam sebesar 122,5mg/KgBB dan 245mg/KgBB selama 8 hari. Fungsi ereksi hewan percobaan dinilai melalui hasil Total Penile Reflex (TPR). Uji statistik yang digunakan adalah Oneway ANOVA. Pemberian ekstrak lada hitam pada tikus hiperglikemia terbukti dapat memperbaiki fungsi ereksi tikus jantan (p<0,001).
Potensi Ekstrak Streptomyces sp. strain i18 sebagai Antibiotik terhadap Bakteri Escherichia coli Alfahri, Farhan Dzaki; Setyaningrum, Endah; Hadibrata, Exsa
Jurnal Penelitian Perawat Profesional Vol 6 No 5 (2024): Oktober 2024, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v6i5.4492

Abstract

Mikroba resisten antibiotik (MRA) merupakan mikroba yang mampu melawan efek antibiotik, sehingga mikroba tersebut tetap tumbuh. Escherichia coli sudah menjadi patogen yang banyak terdapat pada makanan dan minuman yang dapat menyebabkan diare, kolitis perdarahan dan hemolytic uremic syndrome pada manusia. Salah satu sumber metabolit sekunder yang bersifat antibiotik dapat berasal dari genus Streptomyces. Penelitian ini bertujuan untuk mengetahui potensi ekstrak Streptomyces sp strain i18 sebagai antibiotik terhadap bakteri Escherichia coli. Penelitian ini terdiri dari ui fitokimia, uji diameter zona hambat metode sumuran, uji Kadar Hambat Minimum (KHM), Kadar Bunuh Minimum (KBM) dengan bahan uji ekstrak Streptomyces sp strain i18 dengan konsentrasi 5%, 10%, 20%, 40%, 80%, aquadest sebagai kontrol negatif dan siprofloksasin sebagai kontrol positif terhadap pertumbuhan bakteri Escherichia coli. Penelitian ini menunjukkan tidak terdapat diameter zona hambat, KHM dan KBM pada bakteri Escherichia coli oleh ekstrak Streptomyces sp strain i18, hasil uji fitokimia menunjukkan ekstrak Streptomyces sp strain i18 memiliki kandungan metabolit sekunder berupa saponin, triterpenoid dan anthrakuinon glikosida. Hasil penelitian dianalisis menggunakan uji Shapiro-Wilk.
Pengaruh Pemberian Ekstrak Etanol Lada Hitam (Piper nigrum L) Terhadap Kadar Gula Darah dan Jumlah Spermatogonia Model Diabetes Tikus Putih Jantan (Rattus norvegicus) Galur Sprague dawley Talin, Jinan Naura; Hadibrata, Exsa; Rudiyanto, Waluyo; Windarti, Indri
Medula Vol 14 No 12 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i12.1431

Abstract

Diabetes mellitus that is not treated properly can result in infertility. The piperine content in black pepper can help in the quality of spermatogenesis process and blood sugar levels. This study aims to determine the effect of black pepper (P. nigrum L) ethanol extract on blood sugar levels and the number of spermatogonia in a diabetes model of male white rats (R. norvegicus) Sprague dawley strain. The study used a Posttest-only Randomized Control Group on 24 rats divided into 4 groups. All groups were induced with alloxan 150 mg/kgBW except for KN. P1 and P2 were given 122.5 mg/kgBW and 245 mg/kgBW black pepper ethanol extract. Blood sugar levels were checked using Easy Touch GCU with a normal limit of 50-135 mg/dL. The number of spermatogonia was calculated using a tool, namely ImageJ. The data were analyzed using the Shapiro- Wilk normality test and homogeneity test, followed by the Kruskal Wallis non-parametric test and the Post Hoc test. The statistical results of blood sugar levels obtained normally distributed data p>0.05, non-homogeneous data p<0.05, significant Kruskal-Wallis test results and continued Post Hoc test obtained significant results at P2 and K-. The number of spermatogonia obtained normally distributed data p>0.05, non-homogeneous data p<0.05. The results of the Kruskal-Wallis test were significant p<0.05 and continued Post Hoc test obtained significant results at P2 and P1. There was a decrease in blood sugar levels in the administration of black pepper ethanol extract (P. nigrum L) in the diabetes model of male white rats (R. norvegicus) Sprague dawley strain. However, there was no effect of administering black pepper ethanol extract (P. nigrum L) on the number of spermatogonia in the diabetes model of male white rats (R. norvegicus) Sprague dawley strain.
Peningkatan Pengetahuan dan Keterampilan Kader Posyandu Mengenai Deteksi Dini Perkembangan Balita dengan Menggunakan Denver Development Screening Test (DDST) di Posyandu Kecamatan Rajabasa Kota Bandar Lampung Hadibrata, Exsa; Darwis, Iswandi
JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Vol. 5 No. 1 (2020): JURNAL PENGABDIAN MASYARAKAT RUWA JURAI
Publisher : FK Unila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpmrj.v5i1.2803

Abstract

Masa di bawah usia lima tahun (Balita) adalah periode paling kritis yang menentukan kualitas sumber daya manusia. Pada masa balita proses tumbuh kembang berlangsung cepat dan dikatakan sebagai masa emas yang apabila tidak dibina dengan baik akan mengalami gangguan dalam perkembangan emosi, sosial dan kecerdasan. Salah satu Deteksi dini Skrining perkembangan menggunakan Denver Development Skrining Test (DDST) yaitu salah satu tes atau metode skrining yang sering digunakan untuk mendeteksi perkembangan yang dinilai meliputi perkembangan personal sosial, motorik halus, bahasa, dan motorik kasar pada anak. Pemeriksaan DDST dapat dilakukan di tempat dengan kegiatan pemantauan pertumbuhan dan perkembangan seperti di posyandu. Pengabdian ini bertujuan untuk meningkatkan pengetahuan dan keterampilan kader posyandu mengenai dengan metode pelatihan yang dilanjutkan dengan diskusi. Materi penyuluhan yang diberikan mencakup tumbuh kembang anak, DDST, dan praktik pemeriksaan DDST kepada balita. Sebelumnya dilakukan pre test dan diakhiri dengan post test. Kegiatan ini dilaksanakan pada hari sabtu tanggal 1 september 2012. Kegiatan ini diikuti oleh 10 peserta penyuluhan yang terdiri dari ibu-ibu kader posyandu yang ada di wilayah kerja Puskesmas Rajabasa Kota Bandar Lampung. Dari pengisian kuisioner dan pretest diketahui bahwa seluruh (100%) peserta yang mengikuti kegiatan ini belum pernah mendapat penyuluhan kesehatan mengenai perkembangan anak serta pelatihan deteksi perkembangan anak dengan DDST. Sebelum dilakukan pelatihan para peserta tidak mengetahui sama sekali DDST dan setelah dilakukan para peserta sudah mengetahui cara pengisian DDST. Penyuluhan mengenai deteksi dini tumbuh kembang anak menggunakan metode DDST sangat bermanfaat dalam meningkatkan pengetahuan dan keterampilan ibu-ibu kader posyandu.Kata Kunci: DDST, Pemberdayaan kader, Tumbuh kembang
Khitan dan Pengobatan Massal di Masa Pandemi Virus Corona 2019 dengan Penerapan Protokol Kesehatan Adaptasi Kebiasaan Baru di Desa Rejosari Natar Lampung Selatan Tahun 2020 Wintoko, Risal; Fauzi, Ahmad; Hadibrata, Exsa; Siregar, Bintang Abdi; Yusmaidi, Yusmaidi
JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Vol. 5 No. 1 (2020): JURNAL PENGABDIAN MASYARAKAT RUWA JURAI
Publisher : FK Unila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpmrj.v5i1.2810

Abstract

Khitan merupakan tindakan memotong atau menghilangkan sebagian atau seluruh kulit penutup depan dari penis. Khitan sangat bermanfaat untuk kesehatan yaitu mengurangi resiko infeksi saluran kencing, mengatasi fimosis, parafimosis, balaniditis dan dapat mengurangi resiko keganasan penis serta penyebaran penyakit menular seksual. Dalam masa pandemi virus corona banyak orang yang takut melaksanakan khitan dan pengobatan, oleh sebab itu dilaksanakan khitan dan pengobatan massal dengan penerapan protokol kesehatan. Metode pengabdian ini di laksanakan dengan promosi kegiatan pengabdian kepada masyarakat Rejosari, kemudian bagi yang berminat mendaftar ke panitia. Panitia akan melakukan screening untuk peserta khitan massal yang sesuai indikasi. Pelaksanaan kegiatan akan di laksanakan sesuai jadwal yang di tentukan dengan mengikuti protokol kesehatan. Hasil pengabdian masyarakat ini berupa telah di laksanakan pengobatan dan khitan massal di Sekolah Dasar Negeri 3 Rejosari, kecamatan Natar Lampung selatan tanggal 27 Agustus 2020 pada pukul 08.00-12.00 WIB yang di ikuti oleh peserta pengobatan gratis sebanyak 98 pasien dan yang menjalani khitan sebanyak 52 pasien. Petugas kesehatan sebanyak 5 dokter spesialis, 4 dokter umum, 6 perawat dan 27 mahasiswa Fakultas Kedokteran Universitas Lampung. Kesimpulan pengabdian masyarakat ini telah di lakukan khitan dan pengobatan massal terhadap pasien tidak mampu secara ekonomi.Kata kunci: Khitan, Pandemi, Pengobatan
Co-Authors ., Rusliyawati Ade Yonata, Ade Agus Wantoro Al Farisi, Ahmad Fathin Alfahri, Farhan Dzaki Armadani, Melni Atri Sri Ulandari Bayu Anggileo Pramesona Betta Kurniawan, Betta Bilqis, Khorina Fatin Cahyani, Endang Nur Daulay, Suryani A. Dwiputri, Maliya Finda Endah Setyaningrum, Endah Fadli, Muhammada Yogi FAUZAN ABDILLAH Fauzi Ahmad Muda Febrianta, Muhammad Kaisar Firdaus, Purna Fredison, Fredison H R Danarto Happy, Terza A Hasbullah, Faza Hendri Busman Hilmi, Tamadar Ikhsan, Muhammad Al Indri Windarti Intanri Kurniati Isvari, Gusti Ayu Made Prathita Iswandi Darwis Jausal, Anisa Nuraisa Kamalia, Avissa Medina Larasati, Ratri M. Lusina, Septia Eva M. Ridho Ulya Mayasari, Diana Muhammad Maulana Nadifa, Shallu Afdha Oktadoni Saputra, Oktadoni Priyono, Angga Hendro Purnamasari, Haninovita Rahmayani, Fidha Ramdini, Dwi Aulia Rasyid, M. Fauzan Abdillah Risal Wintoko Risti Graharti Rizki Hanriko Rudiyanto, Waluyo Siregar, Bintang Abdi Suharmanto Suherman, Auriva Renasha Susianti Susianti Susianti Sutyarso Sutyarso Sutyarso Talin, Jinan Naura Tjahjo, Mars Dwi Trisula Utomo Untung Tranggono, Untung War, Muhammad Fitra Wardhana, Muhammad Fitra Widia, Chyci Wiwi Febriani Yunianto, Andi Eka Yuningrum, Hesti Yusmaidi, Yusmaidi