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Does FOXP2 gene polymorphism affect the duration of orogastric tube use in moderate to late preterm neonates? A cross-sectional study in Indonesia Mauliza, Mauliza; Dimiati, Herlina; Akmal, Muslim; Imran, Imran
Narra J Vol. 4 No. 3 (2024): December 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i3.933

Abstract

Premature and low birth weight neonates often struggle with oral intake due to immaturity or respiratory distress. Forkhead box protein 2 gene (FOXP2) is predicted to influence oral feeding ability in newborns, but studies assessing the role of this gene in influencing oral feeding ability are limited. The aim of this study was to investigate the role of FOXP2 gene polymorphism, particularly single nucleotide polymorphism (SNP) rs17137124, on the duration of orogastric tube (OGT) use in moderate to late preterm neonates. A multi-center cross-sectional study was conducted in Lhokseumawe, Aceh, Indonesia, from September 2021 to August 2023, involving neonates with 32–36 weeks gestational age. The DNA samples were isolated from the saliva, amplified using polymerase chain reaction (PCR), and the FOXP2 gene was sequenced. The associations between FOXP2 gene polymorphisms and other plausible factors on the duration of OGT use were determined using Chi-squared test, Fisher’s exact test or Pearson correlation as appropriate. Preterm neonates with the CC genotype had the longest OGT use, averaging 3 days (39.1%). TT genotype preterm neonates required OGT use for 4, 5, and 6 days (each 33.3%), while CT genotype neonates predominantly required it for 4 days (41.7%). No significant association was found between FOXP2 genotypes and OGT use duration (p=0.233). Similarly, neonates with C allele required OGT use for 3 and 4 days, while those with T allele mostly required between 4 and 6 days, with no significant association (p=0.110). Analysis using dominant (p=0.109) and recessive models (p=0.481) also showed no significant associations with OGT use duration. However, the study found significant associations between delivery mode (p=0.002) and gestational age (p=0.001) with duration of OGT use in preterm neonates. This study highlights that FOXP2 polymorphisms have limited association with the duration of OGT use among preterm neonates.
Studi Kasus Stunting pada Anak Usia 18 Bulan di Desa Kayee Panyang Puskesmas Bayu Kabupaten Aceh Utara Tahun 2022 Jannah, Jauza Raudhatul; Zara, Noviana; Mauliza, Mauliza; Surayya, Rahmi; Rizaldy, Muhammad Bayu; Siregar, Sarah Rahmayani; Fona, Tischa Rahayu; Al Muqsith, Al Muqsith; Fauzan, Ahmad; Syafridah, Anita
GALENICAL : Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh Vol 3, No 6 (2024): GALENICAL : Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh - November 20
Publisher : Program Studi Kedokteran Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/jkkmm.v3i6.10041

Abstract

Stunting adalah masalah nutrisi kronis yang disebabkan oleh multifaktorial dan terjadi pada lintas generasi. Stunting merupakan bentuk kegagalan pertumbuhan (growth faltering) akibat akumulasi ketidak cukupan nutrisi yang berlangsung lama mulai dari kehamilan sampai usia 24 bulan. Keadaan ini diperparah dengan tidak terimbanginya kejar tumbuh (catch up growth) yang memadai. Selama 20 tahun terakhir, penanganan masalah stunting sangat lambat. Masyarakat di Indonesia sering menganggap tubuh pendek atau tinggi merupakan keturunan. Penelitian membuktikan bahwa faktor keturunan hanya berkontribusi 15%, sementara faktor yang paling besar berkaitan dengan nutrisi, hormon pertumbuhan, dan infeksi berulang. Penelitian ini merupakan sebuah studi kasus terhadap seorang anak balita An. F perempuan berusia 18 bulan di Desa Kayee Panyang Bayu tahun 2022. Studi kasus ini dilakukan dengan cara observasi pasien melalui pendekatan home visit. stunting ditegakkan berdasarkan anamnesa dan pemeriksaan fisik. Setelah diagnosis ditegakkan pasien diberikan edukasi dan tatalaksana secara komprehensif. Dilakukan edukasi tentang stunting dan pemberian berupa nutrisi seperti PMT, susu, multivitamin untuk mempertahankan BB normal dan tumbuh kembang sesuai usia. Kesimpulan studi kasus ini didapatkan bahwa terdapat beberapa faktor yang mempengaruhi kejadian stunting pada anak tersebut, diantaranya adalah tingkat pengetahuan, pola asuh ibu, ekonomi keluarga, dan kurangnya promosi kesehatan.
Sindrom Refeeding Siregar, Mutia Rahmah; Mauliza, Mauliza
GALENICAL : Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh Vol. 4 No. 1 (2025): GALENICAL : Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh - Februari 2
Publisher : Program Studi Kedokteran Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/jkkmm.v4i1.12986

Abstract

Reefeding Syndrome adalah komplikasi penting pada pasien malnutrisi kronik yang terjadi setelah pemberian nutrisi baik secara oral, enteral dan parenteral sebagai respon diet tinggi kalori. Reefeding Syndrome dapat bermanifestasi sebagai gangguan elektrolit ringan tanpa gejala klinis atau gangguan elektrolit berat yang dapat menyebabkan kegagalan organ parah, seperti gagal napas, gagal jantung, kelemahan muskuloskletal dan ensefalopati Reefeding Syndrome dapat mengganggu keseimbangan elektrolit, menimbulkan komplikasi pada berbagai sistem organ dan menyebabkan kematian.
PENGARUH PENGETAHUAN DAN FAKTOR KELUARGA TERHADAP KEBERLANGSUNGAN USAHA INDUSTRI GARAM DI KECAMATAN JANGKA mauliza, mauliza; Wahyuni, Sri; Nova, Nova
Ekonomika : Jurnal Ekonomi dan Pembangunan Vol 15 No 2 (2023): Ekonomika, September 2023
Publisher : Fakultas Ekonomi Universitas Almuslim Bireuen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51179/eko.v15i2.2547

Abstract

This research aims to explain the influence of knowledge and family factors on the sustainability of the salt industry business in Panjang District. The type of data is primary data using quantitative research methods and multiple linear regression model analysis. The results of this research state that knowledge influences the sustainability of the salt industry business. Family factors influence the sustainability of the salt industry business. Simultaneously, knowledge and family factors influence the sustainability of the salt industry business in Panjang District by 20.6%.
Assistance In the Preparation of Teaching Modules Based on Problem Solving Integrated with Character by Utilizing Artificial Intelligence to Junior High School Teachers Nurhafidhah, Nurhafidhah; Mauliza, Mauliza; Yani, Ahmad Fauzi Syahputra
Unram Journal of Community Service Vol. 6 No. 1 (2025): March
Publisher : Pascasarjana Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/ujcs.v6i1.884

Abstract

In the Merdeka Curriculum, one of the stages of lesson planning is the preparation of teaching modules. Teaching modules replace the Lesson Plan (RPP) that teachers typically prepare before teaching. Results from interviews with the principal of SMP Negeri 2 Idi Timur revealed two problems: 1) many teachers still do not understand the principles and structure of preparing teaching modules for the Merdeka Curriculum due to limited intensive training they have participated in for module preparation, and 2) teachers' skills in integrating a learning model with Artificial Intelligence (AI) into the teaching module are still lacking. The urgency of this community service lies in the need to optimize teachers' professional competence by providing training on the preparation of teaching modules based on a character-integrated problem-solving model using Artificial Intelligence (AI). The results of the community service activity showed that 40% of participants were very satisfied with the quality of guidance provided in the preparation of character-integrated problem-solving teaching modules using AI, while 45% and 15% were satisfied and somewhat satisfied, respectively. In another question, 60% of participants stated that the guidance helped improve their understanding of teaching modules and the use of AI
Hubungan Tingkat Pendidikan dan Pengetahuan Ibu Dengan Kejadian Stunting Pada Balita Usia 24-59 Bulan Di Wilayah Kerja Puskesmas Monggeudong Kota Lhokseumawe Berlina, Liza; Sawitri, Harvina; Mauliza, Mauliza
Jurnal Ilmiah Manusia Dan Kesehatan Vol. 7 No. 1 (2024): Jurnal Ilmiah MANUSIA DAN KESEHATAN
Publisher : FAKULTAS ILMU KESEHATAN UNIVERSITAS MUHAMMADIYAH PAREPARE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31850/makes.v7i1.1606

Abstract

Stunting is a nutritional problem in the world, especially in poor and developing countries, stunting is a major health problem associated with the risk of morbidity and mortality, sub-optimal brain development, resulting in delayed motor changes and stunted mental growth. The purpose of this study was to determine the relationship between mother's level of education and knowledge with the incidence of stunting in toddlers aged 24-59 months in the working area of the Mongeudong Public Health Center, Lhokseumawe City. This type of research is an observational analytic study with a cross-sectional design. The total population in this study was 888 people. The sample was taken using a non-probability sampling technique with accidental sampling and obtained a sample of 80 respondents. Data analysis in this study was univariate and bivariate analysis using the chi-square test statistical test. The results of the statistical test showed that the education level variable (p = 0.000 <, a = 0.05) and the knowledge variable (p = 0.000 <, a = 0.05). The conclusion of this study is that there is a relationship between the mother's level of education and knowledge with the incidence of stunting in toddlers aged 24-59 months in the working area of the Mongeudong Public Health Center, Lhokseumawe City.
Gambaran Tingkat Pengetahuan dan Sikap Ibu Hamil Sebelum dan Sesudah Penyuluhan Asi Eksklusif di Wilayah Kerja Puskesmas Wewantara Aceh Utara Tahun 2022 nabila inong ramadhana, salsa; Mauliza, Mauliza; Yudhi Iqbal, Teuku
Jurnal Ilmiah Manusia Dan Kesehatan Vol. 7 No. 1 (2024): Jurnal Ilmiah MANUSIA DAN KESEHATAN
Publisher : FAKULTAS ILMU KESEHATAN UNIVERSITAS MUHAMMADIYAH PAREPARE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31850/makes.v7i1.2712

Abstract

Breast milk (ASI) is a specially produced liquid that comes out directly from a mother's breast for baby consumption. Factors related to exclusive breastfeeding are education, work, knowledge, the role of birth attendants and the age of the mother. The percentage of babies who receive exclusive breastfeeding in Aceh Province is 55.4%. North Aceh is still one of the districts that receives low exclusive breastfeeding at 33%. Knowledge and attitudes can be improved through several methods, one of which is the counseling method. The purpose of this study is to determine the picture of the level of knowledge and attitudes of pregnant women before and after exclusive breastfeeding counseling in the Dewantara Health Center area. This research is a quantitative quasi-experimental research with a type of one group pretest-posttest design with 88 respondents, and a simple random sampling technique. The results showed that the majority of respondents' age was 26-35 years old (56.8%), the majority of respondents' education was high school (56.8%), the majority of respondents' pregnancies were multigravida (78.4%), the majority of respondents' knowledge before counseling was sufficient (62.5%) and after counseling in the good category (100%), and the majority of respondents' attitudes before counseling in the sufficient category (48.9%) and after counseling in the good category (100%). The conclusion of this study is that there are differences in knowledge and attitudes of pregnant women before and after exclusive breastfeeding counseling in the Dewantara Health Center area. Counseling has an influence on the knowledge and attitudes of pregnant women in the Dewantara Health Center area. Keyword : breast milk, Knowledge, Attitude, Education.
Korelasi Pengetahuan dan Sikap Ibu terhadap Perilaku dalam penanganan Demam pada Anak Di Puskesmas Mon Geudong Kota Lhokseumawe Sarah Amanda, Siti; Mardiati, Mardiati; Mauliza, Mauliza
Jurnal Ilmiah Manusia Dan Kesehatan Vol. 7 No. 2 (2024): Jurnal Ilmiah MANUSIA DAN KESEHATAN
Publisher : FAKULTAS ILMU KESEHATAN UNIVERSITAS MUHAMMADIYAH PAREPARE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31850/makes.v7i2.2906

Abstract

Demam merupakan peningkatan suhu tubuh lebih tinggi dari suhu normal yaitu 38,3°C. Peran ibu dalam melakukan penanganan demam dapat membantu dalam mengurangi ketidaknyamanan anak yang didasarkan oleh pengetahuan dan sikap ibu. Pengetahuan dan sikap secara langsung mempengaruhi individu untuk menampilkan perilaku dalam penanganan demam. Penelitian ini bertujuan untuk mengetahui korelasi antara pengetahuan dan sikap terhadap perilaku ibu dalam penanganan demam pada anak di Puskesmas Mon Geudong Kota Lhokseumawe. Metode Penelitian ini menggunakan metode penelitian observasional analitik dengan rancangan cross sectional. Teknik pengambilan sampel dalam penelitian ini menggunakan teknik non probability sampling dengan metode purposive sampling sebanyak 400 orang responden. Hasil penelitian ini menunjukkan karakteristik usia Ibu mayoritas berusia 19-44 tahun (67,8%), mayoritas usia anak 1-5 tahun (35,0%), mayoritas pendidikan responden SMA (181%) dan mayoritas pekerjaan responden tidak bekerja (301%), gambaran penanganan demam pada anak didapatkan pengetahuan baik (63,5%), sikap baik (56,0%) dan perilaku baik (45,3%). Kesimpulan penelitian ini adalah terdapat korelasi yang kuat antara pengetahuan dan sikap terhadap perilaku ibu dalam penanganan demam pada anak di Puskesmas Mon Geudong Kota Lhokseumawe.
Tingkat Risiko Kanker Payudara pada Wanita Usia Subur di Desa Pusong Kecamatan Banda Sakti Dengan Menggunakan Aplikasi Oncodoc Syarafina, Haezah; Rizka, Adi; Mauliza, Mauliza
Jurnal Ilmiah Manusia Dan Kesehatan Vol. 8 No. 2 (2025): Jurnal Ilmiah MANUSIA DAN KESEHATAN
Publisher : FAKULTAS ILMU KESEHATAN UNIVERSITAS MUHAMMADIYAH PAREPARE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31850/makes.v8i2.3523

Abstract

Cancer is a condition characterized by abnormal cell growth that destroys its original form and function.There are several factors that contribute to the increase in breast cancer cases from year to year, such as a lack of socialization about cancer risk reduction activities and a lack of information about early cancer detection.Efforts to detect the level of cancer risk can be done using a smartphone, namely through the oncodoc application.This study aims to determine the risk level of breast cancer in women of childbearing age in Pusong Village, Banda Sakti District by using the oncodoc application.This research is descriptive research, with research methods using cross - sectional design. The total sample was 97 female respondents of childbearing age who met the inclusion and exclusion criteria, and the sampling technique used the Cluster Random Sampling method and also the simple random sampling method. The results of the study showed that the cancer risk level was mostly at a medium risk level 62.9%, followed by a low risk level of 34% and a high risk level of 3.1%.The conclusion of this research is that there is an increase in the risk level of breast cancer so that intervention is needed in the community
Pengaruh Edukasi Penyakit Skabies terhadap Tingkat Pengetahuan, Sikap Dan Perilaku Melalui Video Animasi Berbasis Pop Up pada Siswa MTsS Ulumuddin Kota Lhokseumawe Saputri, Natasya Dewanti; Mauliza, Mauliza; Sofia, Rizka
Jurnal Ilmiah Manusia Dan Kesehatan Vol. 8 No. 2 (2025): Jurnal Ilmiah MANUSIA DAN KESEHATAN
Publisher : FAKULTAS ILMU KESEHATAN UNIVERSITAS MUHAMMADIYAH PAREPARE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31850/makes.v8i2.3567

Abstract

Scabies is a skin infection caused by the mite Sarcoptes scabiei var. hominis, which causes itching in the affected individuals. Scabies can be transmitted directly skin-to-skin contact, indirectly (through objects), poor student hygiene, an unclean environment, and high population density. The purpose of this study is to determine the effect of promotion media in the form of pop-up based animated videos on increasing knowledge, attitudes, and behaviors for scabies prevention among students of MTsS Ulumuddin Lhokseumawe City. The type of research used is a quasi-experiment with a one-group pretest posttest design. The sample used consisted of 100 students using the stratified random sampling technique. Data were collected using questionnaires paper. The statistical test used in this study is the Wilcoxon test, which is used to determine changes in the improvement of knowledge, attitudes, and behaviors towards scabies before and after the intervention. From the research results, it shows that in the good category, there was an increase in knowledge of scabies prevention from 5% to 77%, the attitude variable in the good category increased from 7% to 89%, and the behavior variable in the good category increased from 2% to 90% among students after the intervention. The p-value obtained was < 0.01, indicating an influence on the levels of knowledge, attitude, and behavior of students before and after the intervention. The conclusion of this study is that there is an influence of scabies disease education using animated videos in improvement of knowledge, attitude and behavior.