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Journal : Science Midwifery

"Unveiling cellular immunity: A study on diabetes mellitus patients with gangrene wounds" Meri, Meri; Meisya F, Lisna; Liswanti, Yane
Science Midwifery Vol 12 No 1 (2024): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v12i1.1471

Abstract

Diabetes mellitus experiences disruptions in the immune system, particularly in cellular components. Cells crucial in inflammatory conditions are represented by granulocytes and lymphocytes. However, further explanation is needed regarding the quantities of these cells, especially in diabetes mellitus with gangrene. The research method employed is a quantitative descriptive cross-sectional approach. The research population consists of diabetes mellitus patients with gangrene wounds. The sample size contributing to the study is 14 individuals, representing the total population. Exclusion criteria include patients with other systemic infections. The research findings reveal the frequency distribution of the average granulocyte cell count to be 65.47%, with a standard deviation (SD) of 8.52, a minimum value of 53.3%, and a maximum value of 83.4%. The average lymphocyte cell count is 25.7%, with an SD of 7.97, a minimum value of 10.8%, and a maximum value of 38.7%. In conclusion, the study indicates an increased granulocyte count in 4 individuals or 26.6%, while 10 individuals or 71.4% exhibit normal counts. Conversely, the normal lymphocyte count is observed in 11 individuals or 78.6%, whereas 3 individuals or 21.4% exhibit low counts.
The role of c-reactive protein as an inflammatory marker in normal postpartum: A case study at RSUD, dr. Soekardjo Tasikmalaya Noviana, Dilla; Meri, Meri; Yulianti, Dewi Kania
Science Midwifery Vol 12 No 3 (2024): August: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v12i3.1638

Abstract

The normal delivery process is often followed by pain caused by a ruptured pervaginal wound, which can be the primary focus for assessing the degree of inflammation in the body. The presence of inflammation remains a major concern. One of the most commonly used indicators of inflammation is C-reactive protein (CRP) in response to inflammation, infections, or tissue injury. aimed at measuring CRP levels in normal postpartum patients who have been allowed to return to the hospital, Dr. Soekardjo Tasikmalaya. The samples were taken through purposive sampling and consisted of 30 patients from RSUD Dr. Soekardjo City, Tasikmalaya. The inclusion criteria in this study included patients who did not have a history of diseases such as diabetes, tuberculosis (TB), or lupus. While the exclusion criteria included the refusal of subjects to be respondents and samples who underwent hemolysis and have met the ethical test of the research with the number 043-01/E.01/KEPK-BTH/V/2024. The results of the C-reactive protein examination showed that 26 samples (86,7%) showed positive results and 4 samples (13,3%) showed negative results. So it can be concluded that normal postpartum mothers still have inflammation, especially on the first day.