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Pengaruh Esktrak Daun Krokot (Portulaca oleracea) Terhadap Kadar Malonialdehide (MDA) Pada Tikus Yang Diinduksi Aloksan Sukma Sahreni; Isramilda Isramilda; Rezha Irshadi Ashari
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 2 No. 1 (2023): April :Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v2i1.1920

Abstract

Background: Diabetes mellitus is a degenerative disease caused by the pancreas being damaged in production or insulin cannot work effectively. Portulaca Oleracea Leaf Extract can help reduce levels of Malondialdehyde. The purpose of this study was to analyze the effect of Portulaca Oleracea leaf extract on malondialdehyde levels in alloxan-induced rats as a diabetes model.Methods: There were 30 rats in this study divided into 5 groups, each group consisting of 6 rats. The negative control group was only given aquadest and standard rat feed, the positive group was induced with alloxan, the treatment group 1 was induced with alloxan and Portulaca Oleracea leaf extract at a dose 60 mg/200grBW, treatment group 2 was induced with alloxan and Portulaca Oleracea leaf extract at a dose 90 mg/200grBW and treatment group 3 was induced by alloxan and Portulaca Oleracea leaf extract at a dose 110 mg/200grBW rats. Analysis of the results used the One Way Anova test followed by Post Hoc LSD analysis to see differences between groups.Results: The results of One Way Anova test on Malondialdehyde levels showed that there was an effect after intervention of Portulaca Oleracea leaf extract among the five treatment groups p = 0.000. The results of Post Hoc LSD test showed that Portulaca Oleracea leaf extract had effective inhibits the formation of malondialdehyde activity at a dose of 90 mg/200grBB p = 0.145.Conclusion: It can be concluded that Portulaca Oleracea leaf extract can reduce Malondialdehyde levels.
The Impact of the Middle Ear Microbiota on Otitis Media Outcomes: A Meta-Analysis of Longitudinal Studies Isramilda; Sukma Sahreny
Sriwijaya Journal of Otorhinolaryngology Vol. 3 No. 1 (2025): Sriwijaya Journal of Otorhinolaryngology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjorl.v2i2.156

Abstract

Introduction: Otitis media (OM), a prevalent middle ear inflammation, often involves microbial colonization. The composition of the middle ear microbiota may influence OM outcomes, including recurrence, persistence, and treatment response. This meta-analysis investigated the relationship between the middle ear microbiota and OM outcomes. Methods: Longitudinal studies published from 2018 to 2024 that explored the middle ear microbiota and OM outcomes were systematically searched in PubMed, Embase, and Web of Science. Data on study design, participant characteristics, microbiota analysis, and OM outcomes were extracted. The risk of bias was assessed using the Newcastle-Ottawa Scale. A random-effects model was used to pool effect estimates. Results: A total of 15 studies (n = 2,540 participants) met the inclusion criteria. The middle ear microbiota diversity was significantly lower in children with recurrent OM compared to those without (standardized mean difference [SMD] = -0.45, 95% confidence interval [CI] -0.62 to -0.28, p < 0.001). The presence of specific pathogens, including Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis, was associated with an increased risk of OM recurrence (odds ratio [OR] 1.75, 95% CI 1.32 to 2.31, p < 0.001). Additionally, microbial dysbiosis was associated with delayed resolution of OM and increased antibiotic treatment failure. Conclusion: The middle ear microbiota composition significantly impacts OM outcomes. Reduced diversity and specific pathogens are associated with increased OM recurrence. These findings highlight the potential for microbiota-targeted interventions in OM management.
PENANGGULANGAN STUNTING MELALUI PENINGKATAN PARTISIPASI MASYARAKAT DENGAN SOSIALISASI DAN EDUKASI STUNTING DI KELURAHAN BATU BESAR sahreni, Sukma; Isramilda; Asral; Mia Firauhinnur; Rizky Srikandi
Jurnal Pendekar Nusantara Vol. 1 No. 1 (2023): OKTOBER 2023
Publisher : LPPM-Universitas Batam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37776/pend.v1i1.1224

Abstract

Stunting merupakan masalah gizi yang disebabkan karena kekurangan asupan gizi dalam waktu lama pada masa 1000 hari pertama kehidupan (HPK) yang merupakan masa kritis untuk pencegahan stunting salah satunya pemberian MP ASI yang tepat. MPASI adalah makanan pendamping yang diberikan saat anak usia 6 bulan ke atas untuk menunjang kebutuhan gizi bagi pertumbuhan anak. Pada pengabdian masyarakat ini digunakan media promosi leaflet dan untuk mengetahui tingkat pengetahuan ibu dilakukan pre-test sebelum penyuluhan dan post-test setelah penyuluhan hasil dari test menunjukkan peningkatan pengetahuan ibu setelah edukasi stunting dan MPASI/PMT. Pada saat pre-test tingkat pengetahuan ibu kategori kurang sebanyak 10 orang (55,5%), sedangkan dengan katergori baik 8 orang (44,4%). Pada saat post-test tingkat pengetahuan ibu dengan kategori kurang adalah sebanyak 2 orang (11,1%) dan dengan kategori baik sebanyak 16 orang (88,8%).
PENDAMPINGAN KELAS IBU HAMIL DALAM MEMBERIKAN MOTIVASI ANC BERKUALITAS, UPAYA PENINGKATAN KESEHATAN IBU DAN JANIN Yenni Aryaneta; Mariyana; Isramilda
Jurnal Pendekar Nusantara Vol. 1 No. 2 (2024): FEBRUARI 2024
Publisher : LPPM-Universitas Batam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37776/pend.v1i2.1326

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Complications of pregnancy and childbirth as a cause of maternal death can be prevented by carrying out regular antenatal care (ANC) visits. Antenatal care is a comprehensive and quality antenatal service provided to all pregnant women. These services can be provided by doctors, midwives, nurses and other medical personnel who are trained and professional. The Indonesian government has made a policy for an integrated antenatal care program of quality and quantity, namely that antenatal care must implement the "7T" service standard with a minimum visit frequency of 4 times during pregnancy. Antenatal services can also be used to provide information to pregnant women and their families to carry out appropriate treatment and immediately have their pregnancy checked if there are danger signs during pregnancy. Factors that influence the health behavior of pregnant women when visiting ANC are divided into predisposing factors, enabling factors and reinforcing factors. Predisposing factors consist of age, education level, occupation, parity, knowledge and attitudes of pregnant women. Enabling factors include distance from residence, family income, and existing information media facilities. Meanwhile, strengthening factors include husband's support, family support, and attitudes and support from health workers..
Environmental Quality Development Strategy in Central Government Areas: Case Study of Dompak Island, Riau Islands Province Roby Cahayadi; Yuanita FD Sidabutar; Cevy Amelia; Isramilda
JMKSP (Jurnal Manajemen, Kepemimpinan, dan Supervisi Pendidikan) Vol. 9 No. 1 (2024): JMKSP (Jurnal Manajemen, Kepemimpinan, dan Supervisi Pendidikan)
Publisher : Graduate Program Magister Manajemen Pendidikan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31851/jmksp.v9i1.14783

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Environmental quality refers to the state or condition of the environment in a particular area, taking into consideration various factors that affect the well-being of living organisms, including humans. It encompasses the health and sustainability of ecosystems, air, water, soil, and other natural resources. The interpretation of environmental quality as providing optimal carrying capacity for human survival implies that the environment should meet certain criteria to support human life and well-being. This research aims to find out how to apply and development strategy in providing regional facilities and infrastructure to optimize environmental quality on Dompak Island as the Central Government Area of the Riau Islands Province. This research uses a qualitative method with a descriptive approach through SWOT analysis. The research results found that the strategy for providing facilities and infrastructure to improve environmental quality on Dompak Island is by developing a drinking water supply system (SPAM), increasing drainage capacity, providing street lighting infrastructure, providing green open space, maintaining existing physical infrastructure, utilizing empty land. for the construction of parking lots, collaboration with other parties and strengthening regional management institutions. The novelty of this research involves various infrastructure components, effective use of resources, multi-party collaboration, institutional strengthening, and strategies based on SWOT analysis to achieve the goal of improving sustainable environmental quality on Dompak Island.
The Role of Innate and Adaptive Immunity in Staphylococcal Scalded Skin Syndrome: A Systematic Literature Review Isramilda; Andi Ipaljri
Scientific Journal of Dermatology and Venereology Vol. 2 No. 1 (2024): Scientific Journal of Dermatology and Venereology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjdv.v1i2.50

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Introduction: The innate immune system provides immediate protection in the event of an infection, while the adapted immune system provides a more specific response and has the ability to remember specific pathogens, thereby protecting the body from similar infections in the future. This study aimed to present the role of innate and adaptive immunity in staphylococcal scalded skin syndrome (SSSS). Methods: The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the role of innate and adaptive immunity in staphylococcal scalded skin syndrome. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Results: Five studies were included in this study. A combination of innate and adapted immune systems work together to overcome SSSS infections. Conclusion: The innate immune system provides a rapid initial defense, while the ad apted immune system provides a more specific response and the ability to form immune memory.
Hubungan Kebiasaan Mengorek Telinga Dengan Kejadian Otomikosis Pada Pasien di Poliklinik THT Rumah Sakit Budi Kemuliaan Kota Batam Elvita Nora Susana; Isramilda Isramilda; Ike Nurjanah
Vitalitas Medis : Jurnal Kesehatan dan Kedokteran Vol. 1 No. 2 (2024): April : Vitalitas Medis : Jurnal Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/vimed.v1i2.135

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Otomycosis is an ear infection caused by fungi, or a superficial fungal infection of the pinna and meatus auditorius - externus. The most common symptom is itching. Ear scraping causes disruption of the natural ear cleaning mechanism so that it is easy to develop otomycosis. Indonesia with a tropical climate has a high level of humidity causing fungal infections to occur easily in the human body, such as in the ear canal or called otomycosis. This study aims to determine the relationship between the habit of picking ears with the incidence of otomycosis in the ENT Polyclinic of Budi Kemuliaan Hospital, Batam kota in 2023. This study used an observational analytic design with a cross sectional design. The population in this study were all patients at the ENT Polyclinic of the Budi Kemuliaan Hospital, Batam Kota in 2023 with purposive sampling technique taking total sampling on a sample of 70 people. Data were analyzed using the chi square test. The results of this study obtained variables associated with the incidence of Otomycosis. Where with a frequency of >1x / week (often), 75% experienced otomycosis and ≤1x / week (rarely), 34.6% experienced otomycosis. There was a significant relationship between the frequency variable and the incidence of otomycosis (p value = 0.001). Based on the results of this study, it can be concluded that there is a relationship between the habit of scraping the ears with the incidence of otomycosis in patients of the ENT Polyclinic of Budi Kemuliaan Hospital, Batam Kota 2023.
HUBUNGAN STRES DENGAN KEJADIAN HIPERTENSI PADA PEKERJA MITIGASI PEMADAM KEBAKARAN DI KOTA BATAM Slamet Sudi Santoso; Isramilda; Angel Manik
Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam Vol 14 No 2 (2024): Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam
Publisher : Universitas Batam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37776/zked.v14i2.1529

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Background: Hypertension is a condition where the blood vessels experience a continuous increase, while diastolic blood pressure is the blood pressure when the heart relaxes. This hypertension can be influenced by several factors, especially stress. Stress is a state or condition that arises due to the inability of a person experiencing stress to deal with stressors including circumstances and biological, psychological and social resources. One job that can be at risk of hypertension due to work stress is firefighting, because this job involves repeated exposure to traumatic events that can cause psychological problems. Method: This research uses quantitative methods through a cross sectional approach. This research was conducted at Batam University in December-January 2023/2024. The sampling technique used Isaac Michael's formula with a sample size of 43 out of 110 workers Result: The results of the analysis test using the Spearman Rank test showed a p result of 0.002 (<0.05), indicating that there was a significant relationship between stress levels and the incidence of hypertension. with a Spearman Rank correlation coefficient value of 0.432. Conclusion: Based on the research results, it was found that there was a relationship between stress and the incidence of hypertension in firefighting mitigation workers in Batam City in 2023.
UJI EFEKTIVITAS ANTIBAKTERIEKSTRAK JAHE MERAH (Zingiber Officinale Var. rubrum) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus Aureus SECARA IN VITRO Isramilda; Sukma Sahreni; Salamatun Nisa
Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam Vol 14 No 3 (2024): Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam
Publisher : Universitas Batam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37776/zked.v14i3.1546

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Latar Belakang : Staphylococcus aureus merupakan bakteri patogen oportunistik yang dapat ditemukan di permukaan kulit dan permukaan mukosa di beberapa organ manusia. Jahe merah (Zingiber officinale. var rubrum) mengandung senyawa Flavonoid, Fenol, Terponoid, dan Minyak astiri yang dapat menghambat pertumbuhan bakteri. Penelitian ini bertujuan untuk mengetahui efektivitas ekstrak jahe merah dengan konsentrasi 60%, 80%, dan 100% terhadap pertumbuhan bakteri Staphylococcus aureus. Metode : Penelitian ini adalah penelitian eksperimental menggunakan rancangan secara acak dengan tes dan kelompok kontrol (The Randomized Posttest Only Control Group Design). Ekstrak jahe merah diperoleh melalui metode maserasi yang direndam pelarut etanol 95%. Untuk mengetahui efektivitas ekstrak jahe merah terhadap pertumbuhan bakteri Staphylococcus aureus dilakukan uji in vitro dengan metode difusi cakram. Hasil : Hasil uji efektivitas ekstrak jahe merah terhadap Staphylococcus aureus menunjukkan adanya zona bening di sekitar kertas cakram yang menandakan terhambatnya pertumbuhan bakteri dengan konsentrasi yang paling efektif adalah 80%. Kesimpulan : Berdasarkan hasil penelitian ini diketahui bahwa Ekstrak jahe merah efektif dalam menghambat pertumbuhan Staphylococcus aureus. Kata kunci : Uji Efektivitas Antibakteri, Jahe Merah (Zingiber Officinale Var. rubrum), Pertumbuhan Bakteri Staphylococcus aureus.
PENCEGAHAN BULLYING PADA ANAK SEKOLAH MENENGAH ATAS DI SMA ISLAM NABILAH KECAMATAN BATAM KOTA Isramilda; Cevy Amelia; Alkausar Saragih
Jurnal Pendekar Nusantara Vol. 2 No. 2 (2025): FEBRUARI 2025
Publisher : LPPM-Universitas Batam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37776/pend.v2i2.1649

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Kegiatan Pengabdian Kepada Masyarakat (PKM) yang dilaksanakan oleh para dosen Universitas batam dan UMN Al-Washliyah bertujuan untuk melakukan penyuluhan dalam program pengabdian masyarakat yang dapat berupa kegiatan penyuluhan, pendampingan. Salah satu permasalahan yang dirasa perlu diwaspadai adalah dalam hal pergaulan dengan sesama siswa SMA. Berdasarkan pengamatan pihak sekolah, dalam hal ini adalah guru, pergaulan siswa SMA dirasakan semakin “berani”. Dalam arti terkadang “melupakan” resiko atau bahaya yang dihadapi nya. Jika ditelaah lebih lanjut, maka perilaku berisiko di kalangan siswa SMA dapat disebabkan karena adanya proses adaptasi dalam menghadapi masa pubertas dan juga dalam menghadapi perubahan gaya pergaulan di masa remaja. Perilaku berisiko yang menjadi permasalahan yang marak terjadi adalah perilaku yang terkait dengan bullying serta perilaku yang terkait pemahaman akan seksualitas.