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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) The Journal of Pure and Applied Chemistry Research Biology, Medicine, & Natural Product Chemistry Majalah Obat Tradisional Public Health of Indonesia Jurnal Surya Medika Jurnal SOLMA JMM (Jurnal Masyarakat Mandiri) Pharmacology and Clinical Pharmacy Research Jurnal Ilmu Kefarmasian Indonesia Science Midwifery Jurnal Mandala Pengabdian Masyarakat Journal SAGO Gizi dan Kesehatan Journal of Experimental and Clinical Pharmacy (JECP) Sasambo Journal of Pharmacy Jurnal Pengabdian Ilung (Inovasi Lahan Basah Unggul)
Ysrafil, Ysrafil
Departemen Farmakoterapi, Fakultas Kedokteran, Universitas Palangka Raya
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Upaya Menekan Penyakit Menular dan Tidak Menular melalui Pendekatan Edukasi Kesehatan Berbasis Herbal dan Pendampingan Latihan Fisik Ysrafil, Ysrafil; Komara, Nisa Kartika; Hanasia , Hanasia; Pratika, Remi Ayu; Ahmad, Farah Fauziyah Radhiyatulqalbi
Jurnal SOLMA Vol. 14 No. 3 (2025)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v14i3.20891

Abstract

Background: Based on Indonesian Health Survey, Central Kalimantan has the highest prevalence of hypertension in Indonesia (40.7%). A similar situation occurs in Pahandut Seberang, In 2024, hypertension among top three most common diseases alongside respiratory tract infections and scabies, with 200, 290, and 190 cases out of 1,831 residents. The high incidence rate is influenced by excessive salt consumption, smoking, lack of physical activity, and geographical conditions prone to flooding. Recently, community has mostly used conventional drugs that cause side effects, while small number have tried herbal medicines, but their processing has not been appropriate. Method: To address these issues, our team implemented community service program consisting of education on hypertension, ISPA, and scabies, training on innovative herbal products, and physical exercise guidance (aerobic exercises, elderly exercises, and yoga) by involve of professional instructors. Results: The post-test results showed an increase in the cadres' understanding of educational material. Participants were also able to independently practice processing herbal plants into useful products (herbal tea, liquid soap, aromatherapy candles, and herbal creams) and demonstrate the physical exercises they had been taught. The community showed high enthusiasm, accompanied by appreciation and gratitude for the activities. In addition, the community service team teach cadres in obtaining PIRT (Traditional Food Product Registration) to support the sustainability of herbal products. Conclusion: The program successfully improved the knowledge, skills, and independence of cadres in processing herbs and performing physical exercises, thereby becoming strategic to prevent and reduce the incidence of communicable and non-communicable diseases in Pahandut Seberang
Evaluation of the combination patch of betel leaf extract (Piper sp.) - ultrasonic assisted extraction as a transdermal delivery system on fibroblast cell formation and collagen density Valencia, Regina; Trinovita, Elsa; Shinta, Herlina Eka; Toemon, Angeline Novia; Ysrafil, Ysrafil
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 23 No. 1 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i2.1687

Abstract

The combination of red betel (Piper crocatum) and green betel (Piper betle L.) leaves is believed to act synergistically in enhancing wound healing. Transdermal patches offer advantages over conventional topical forms due to their sustained drug release, ease of application, and prolonged therapeutic effect. This study evaluated the histopathological effects of a combination patch containing betel leaf extracts for incision wound treatment in Wistar rats. The studies used an true experimental post-test-only control group design, five groups were tested: a blank patch (K−), a povidone-iodine patch (K+), and combination extract patches at concentrations of 7.5% (K1), 15% (K2), and 30% (K3), applied over 14 days with six animals per group. Patch characteristics were assessed through organoleptic tests, thickness, weight uniformity, folding endurance, and pH, while wound healing was evaluated through histological analysis of fibroblast cell counts and collagen density. Statistical analysis was conducted using the Kruskal-Wallis test followed by Mann-Whitney post-hoc tests. The 30% combination patch (K3) showed the most significant healing effect, with fibroblast counts exceeding 50 cells and dense collagen formation scoring +3. These results indicate that a transdermal patch combining Piper crocatum and Piper betle L. extracts effectively promotes wound healing by enhancing fibroblast proliferation and collagen synthesis.
Co-Authors Agnes Frethernety Ahmad Sukrianur Alayya Adistia Putri Alexandra, Francisca Diana Angeline Novia Toemon, Angeline Novia Anugerahny, Margaretha Yayu Indah Ardi Sandriya Dali Dali Damiti, Sukmawati A Damiti, Sukmawati Ahmad Denny Indra Setiawan Desyandri Desyandri Dwi Hermayantiningsih Elsa Trinovita Erwin Prasetya Toepak Erwin Prasetya Toepak Fariz Noorrahman, Nabil Fatmaria Fatmaria Fatmaria, Fatmaria Fihrina Mohamad Francisca Diana Alexandra Frethernety, Agnes Hakim, Muh. Supwatul Halisa, Nida Hanasia , Hanasia Hanasia Hanasia Hanasia, Hanasia Harlyanti Muthma'innah Mashar Hartati Hartati Hartati Hartati Havid, Husnul Indwiani Astuti Irmawan, Muhammad Ishak, Pratiwi Ismail Ismail Komara, Nisa Kartika Marvin Horale Pasaribu Mashar, Harlyanti Muthma’innah Miranti Maya Sylvani Muhammad Irmawan Natalia Sri Martani Oktriani R Permatasari, Silvani PRISCA SAFRIANI WICITA Rahman, Sudarman Rahmawati Halim Rahmawati, Rahmawati Ranintha br Surbakti Remi Ayu Pratika Rian Ka Praja Sari, Meiyanti Ratna Kumala Sa’adah N Sinuhaji, Masira Sony Crespo Sirait, Christine Sofia Mubarika Haryana Stevin Carolius Angga Sukmawati A. Damiti Sukmawati Damiti Sulistina, Dinda Ananda Syamsul Thalib Teguh Aryandono Tesalonika, Lidya Toemon, Agnes Immanuela Torizal GF Turnip, Oktaviani Naulita Valencia, Regina Vyani Kamba Wardana T Yuliana Yusuf, Ghaitsa Zahira Sopha Zaenal Abidin Zhofiroh, Nabilatul