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Gunanti .
Departemen Klinik, Reproduksi Dan Patologi Fakultas Kedokteran Hewan Institut Pertanian Bogor, Bogor
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Public Health Social Sciences Veterinary Other

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ELECTROCARDIOGRAM OF PIGS (Sus scrofa) ANESTHETIZED WITH A COMBINATION OF KETAMINE-MEDETOMIDINE AND KETAMINE-ACEPROMAZINE Jessica Anggun Safitri; Gunanti Gunanti; Deni Noviana; Sus Derthi Widhyari
Jurnal Kedokteran Hewan Vol 14, No 4 (2020): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v14i4.16984

Abstract

This study aims to evaluate and compare the effects of the combination of ketamine-medetomidine and ketamine-acepromazine anesthesia on pig electrocardiogram (ECG) images. The study was conducted to see the ECG Leads II in six pigs which were divided into two groups. Group I (K1) was given a combination of ketamine (10 mg/kg BW) and medetomidine (0.08 mg/kg BW), while Group II (K2) was given a combination of ketamine (22 mg/kg BW) and acepromazine (1.1 mg/kg BW) intramuscularly. ECG recording was performed after the pigs were anesthetized at the surgical stage by attaching the recording electrodes to the front wall of the chest, front left and right ankles, and back right and left back ankles. The ECG recording used 1 voltage (1 cm = 1mV) with a speed of 25 mm/sec. The parameters observed were heart rate frequency, heart rhythm, P duration, P amplitude, PR interval, R amplitude, QRS interval, QT interval, ST segment, T wave, and Mean Electrical Axis (MEA). Data obtained from this study were analyzed by T-test. The results showed that K1 had an average heart rate of 100 x/minute, regular heart rhythm, P duration of 0.07 sec, P amplitude of 0.27 mV, PR interval of 0.17 sec, R amplitude of 0.75 mV, QRS interval of 0.05 sec, QT interval of 0.20 sec, ST segment of 0.17sec, T wave of 0.17 mV, and MEA of 83.60°; meanwhile, K2 had an average heart rate of 122 x/minute, regular heart rhythm, P duration of 0.06 mm/sec, P amplitude of 0.23 mV, PR interval of 0.14 sec, R amplitude of 0.80 mV, QRS interval of 0.04 sec, QT interval of 0.16 sec, ST segment of 0.14 sec, T wave of 0.12 mV, and MEA of 68.60. The ketamine-medetomidine combination produced good quality of anesthetics for the cardiovascular system.
3. Malignant Testicular Neoplasia in Male Pig with Scrotal Hernia and Testicular Cyst: A Case Report Gunanti Gunanti; Dwi Utari Rahmiati; Harits Abdullah Munir; Tytha Nadhifa Winarto; Septi Nurcholida Sari; Himah Nuradilah; Dina Zuhdina Rahman
Jurnal Medika Veterinaria Vol 15, No 2 (2021): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v15i2.22105

Abstract

A 4 month old male pig weighing 18.5 kg has enlarged testes. The mass in the scrotum is enlarge rapidly within 1 month, there is no known castration history of this animal. Pigs have a fairly good appetite, but have persistent diarrhea. Physical and supporting examinations (radiography, ultrasonography, hematology and blood chemistry) were performed. Radiographic results showed radiopaque nodules in the lungs, gas distension in the fundus and intestines that were imaged radiolucently, and radiopaque masses in the testis-scrotum. Based on the results of ultrasonography, it is known that the bladder is surrounded by intestinal organs and some anechoic areas are seen on the sonogram of the testes. Hematological and blood chemistry data obtained showed that the animals had hypochromic anemia, decreased ALP values, and had leukocytosis. The results of the investigations carried out were not clear enough to determine the cause of the enlargement of the pig's testicles, so a surgical approach was carried out with a dubius-infausta prognosis. The results of this approach were adjusted with the results of the previous investigations and concluded that the pigs had malignant testicular neoplasia, scrotal hernia, and testicular cyst.
7. Leukocyte Profile and Bone Fracture Recovery post Scaffold Biphasic Calcium Phosphate/Alginate implantation in Sheep Gunanti Gunanti; Ki Agus Dahlan; Afiqah Binti Abd Latif; Liza Oktafani; Selma Laily Nur Afifa; Shayrilia Ivanovanny Angesti; Rr Soesatyoratih; Sus Derthi Widyari; Erwin Erwin
Jurnal Medika Veterinaria Vol 14, No 1 (2020): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v14i1.17101

Abstract

 The purpose of this study is to evaluate the leukocyte profile and bone fracture recovery post scaffold biphasic calcium phosphate/alginate implantation in the sheep’s os tibia. Three sheeps involved in this study and defect is made on each left and right os tiba. Left os tibia as a control while scaffold biphasic calcium phosphate/alginate is implanted on the right os tibia. Blood is collected before and after implantation to be evaluated, while the radigoraph is used to evaluate the bone fracture recovery post biphasic calcium phosphate/alginate implantation. The result shows that scaffold biphasic calcium phosphate/alginate has no significant effect to the leukocytes profile and shows a good result on affecting the recovery process of bone fracture, although it stil not able to increase the recovery periods.
6. Erythrocyte Profile of Male Piglet Aged 31-Day Old (Sus scrofa domestica) in the Laboratory Animal Management Unit IPB University Gunanti Gunanti; Damiana Rita Ekastuti; Dwi Utari Rahmiati; Muhammad Fajrul Falah; Erwin Erwin
Jurnal Medika Veterinaria Vol 15, No 1 (2021): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v15i1.22130

Abstract

Domestic pig (Sus scrofa domestica) is well known as animal that used frequently as a research animal due to their similarity to human both in  terms of anatomy and physiology. Information regarding  standard value of domestic piglet’s hematology in Indonesia are still limited. The aim of this study was to obtain erythrocyte profiles of domestic piglets in Animal Laboratory and Research Unit, Bogor Agricultural University. The results of this study are expected to be used as an erythrocyte profiles reference of domestic piglets in Indonesia. Blood samples were collected from six male piglets in Animal Laboratory and Research Unit, Bogor Agricultural University through auricular vein, then the samples were put into a vaccuum tube containing anticoagulant (K3EDTA) for further test using hematology analyzer. The parameters used in this study consist of erythrocyte count, hemoglobin concentration, hematocrit, and erythrocyte indices. Data were analyzed descriptively in the form of mean ± standard deviation (minimum–maximum). The results of this study showed that the average of erythrocyte counts were 6,42 ± 1,03 millions/µL with 8,30 ± 1,51 g/dl hemoglobin concentration, hematocrite 29,80 ± 5,10%, MCV 46,47 ± 1,62 fL, MCH 12,83 ± 0, 65 pg, MCHC 27,75 ± 0,71 g/dL, and RDW 28,87 ± 3,86%.
Penyembuhan luka sayatan kulit menggunakan topikal balsamum peruvianum pascaoperasi infark miokardium pada babi domestik (Sus scrofa domestica) Febryanto, Agung; Rahmiati, Dwi Utari; Wientarsih, Ietje; Murtiningrum, Fitria Senja; Iman, Bintang Nurul; Noviana, Deni; Gunanti, Gunanti
Current Biomedicine Vol. 1 No. 1 (2023): January
Publisher : School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/currbiomed.1.1.25-32

Abstract

Background: Swine are ideal animal models used for human health and disease research in humans because they have similar anatomy and physiology, one of which is regarding wound healing. Objective: This study aims to determine the effectiveness of balsamum peruvianum on wound healing after myocardial infarction surgery in domestic pigs (Sus scrofa domestica). Methods: The study used five pigs aged 4–5 months, three male and two female. The incision was made using electrocautery in the lateral part of the third and fourth thoracic intercostal spaces, lengthwise from dorsal to ventral. The wound was sutured using Monosyn® 4.0 thread with a subcuticular/intradermal suture pattern. The wound was then given 10% iodine and 10% balsamum peruvianum over the entire surface of the wound twice a day. Recovery was observed on 1st, 4th, 7th, 11th, and 14th days and was scored (grade: 1–4) on macroscopic examination in each pig until day 18th. Results: The observations showed a significant difference in recovery scores on the 11th and 18th days compared to the first day. Conclusion: Topical balsamum peruvianum can be used and is effective for wound healing of skin incisions after myocardial infarction surgery in swine.
PENGEMBANGAN MEDIA ASESMEN PEMBELAJARAN BERBASIS WORDWALL PADA MATERI SIFAT ALLAH SWT TERHADAP MINAT SISWA KELAS VII MTS TERPADU BERKAH PALANGKA RAYA Anhu Raja; Gunanti Gunanti; Lijar Pastilah
ADIBA : JOURNAL OF EDUCATION Vol. 4 No. 4 (2024): OKTOBER
Publisher : CV. ADIBA AISHA AMIRA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This research aims to develop Wordwall-based learning assessment media on the nature of Allah SWT in class VII at MTs Terpadu Berkah Palangka Raya. Using the "Research and Development" (R&D) method, this research involves validation by material and media experts, which shows results that are worthy of being tested. Product trials show that this media can increase students' interest and motivation in the learning process. The research results show that 81% of students feel more enthusiastic when using this media, while 76% of teaching staff support its implementation. Wordwall-based assessment media not only helps understanding the material, but also creates a more interactive and interesting learning atmosphere, so that it can overcome limited infrastructure and policies in schools.
EFFECTIVENESS OF STEM CELL THERAPY IN MYOCARDIAL INFARCTION BASED ON ENZYME ACTIVITY AND LIVER HISTOPATOLOGY Rahmi, Riska Asria Sa'adatur; Gunanti, Gunanti; Noviana, Deni; Harlina, Eva
Jurnal Kedokteran Hewan Vol 18, No 4 (2024): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i4.30881

Abstract

This research aims to study the effectiveness of single placenta stem cell therapy (ST) or a combination of cardiomyocyte co-cultures in pigs with myocardial infarction based on enzymes alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activity as well as liver histopathology. Nine pigs were divided into three treatment groups (K1, K2, and K3) consisting of three pigs per group. Blood sampling was performed one-hour pre-surgery, post-ST-elevation, and eight weeks post-therapy. The experimental animals were treated for eight weeks, then euthanized and necropsied for liver removal. ALT and AST values were analyzed using one-way analysis of variance (ANOVA) and followed by Tukey's test. Histopathological changes in liver tissue were analyzed using Image J 1.53 software, and the measured data were analyzed using oneway ANOVA. The results showed an increase in the ALT and AST values of the three treatment groups on post-ST-elevation blood sampling but were still within normal limits except for K1. ALT and AST values decreased significantly (P0.05) in the group treated with single placental stem cell (K2) or combined cardiomyocyte co-culture (K3). The ALT value of K3 decreased but not significantly (P0.05) compared to K2. The AST value of K3 decreased significantly (P0.05) but was not significantly different (P0.05) compared to K2. The liver tissue showed circulatory disturbances in the central venous congestion, portal vein, sinusoidal dilatation and congestion, and hepatocyte changes in the form of centrilobular necrosis and hydropic degeneration. Stem cell therapy alone (K2) or in combination with cardiomyocyte co-culture (K3) had similar percentage of centrilobular necrosis which was significantly lower than K1 (P0.05). Hepatocyte hydropic degeneration on K2 was classified as mild, whereas on K3 was classified as moderate. As conclusion, administration of placental stem cell therapy alone or in combination with cardiomyocyte co-culture can reduce ALT and AST values and could repair liver tissue.
EFFECTIVENESS OF SUGAR DRESSING TREATMENT OF LAWANG SUGAR CANE ORIGIN ON INCISIONS WOUND HEALING OF RABBIT SKIN Rezeki, Sri; Gunanti, Gunanti; Subangkit, Mawar
Jurnal Kedokteran Hewan Vol 18, No 3 (2024): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i3.33524

Abstract

The aim of this research was to determine the effectiveness of sugar dressing treatment from Lawang sugar cane on incision wound healing process of rabbit skin. Nine New Zealand white rabbits were divided into three treatment groups with three rabbits per group. In negative control group (KN), the wounds were only treated with distilled water, while in SD60 and SD100 groups, the wounds were treated with 60% and 100% sugar solution, respectively. The treatment was given once daily for 7 days. The results showed that the sugar dressing treatments have significant effect (P0.05) on the size of the wound area and increased the collagen density, but did not have significant effect on the remaining length of the wound.Based on the results of the study, it can be concluded that sugar dressing dressing treatment from Lawang sugar cane is effective in increasing collagen density in the wound healing process.
EFFECTIVENESS OF STINGLESS BEE HONEY IN INCREASING COLLAGEN IN THE SKIN WOUND HEALING OF RATS Maulana, M Ridha; Gunanti, Gunanti; Subangkit, Mawar
Jurnal Kedokteran Hewan Vol 19, No 1 (2025): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v19i1.44574

Abstract

The purpose of this study was to determine the effectiveness of stingless bee honey in healing incision wounds on rat skin based on collagen formation. A total of 30 Sprague-Dawley rats were divided into 3 observation days (n= 10 rats). The incisions performed on all rats but given different treatments. In negative control group, the incision wound was not treated, while in positive control, the incision was treated with bioplacentom. Rats in treatment 1 and treatment 2, the incision wound were treated with 75% and 100% stingless bee honey treatment was given once a day for 7 days. The results showed that the 75% and 100% stingless bee honey groups showed a significant effect on reducing the wound length and increasing the collagen density (P0.05). As conclusion, stingless bee honey is effective in increasing collagen density in the wound healing process of rat.
Pengenalan Bulan Hijriah Melalui Media Smart Box Terhadap Santri TP Al-Qur’an Syuhada Sardimi, Sardimi; Gunanti, Gunanti; Amelia Putri, Yusika; Surawan, Surawan
JURPIKAT (Jurnal Pengabdian Kepada Masyarakat) Vol. 6 No. 2 (2025)
Publisher : Politeknik Piksi Ganesha Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37339/jurpikat.v6i2.2375

Abstract

Artikel ini dilatarbelakangi oleh minimnya penggunaan media dalam penyampaian materi yang menarik seperti Smart Box di TP Al-Qur'an Syuhada. Smart Box merupakan alat peraga berbentuk persegi yang terdiri dari empat sisi yang berisi kartu gambar dan kartu kata. Pentingnya penggunaan media Smart Box dalam kegiatan pembelajaran adalah untuk menarik minat siswa dalam mempelajari materi yang disampaikan, salah satunya materi bulan Hijriah. Penggunaan media pembelajaran Smart Box diharapkan dapat menjadi solusi inovatif untuk meningkatkan pemahaman dan keterlibatan siswa dalam mempelajari materi tersebut. Metode yang digunakan adalah Service Learning (SL). Berdasarkan hasil penggunaan media Smart Box dalam penyampaian materi bulan Hijriah telah banyak mengalami kemajuan, antara lain: meningkatnya pemahaman dan keterampilan siswa serta semangat belajar terkait materi bulan Hijriah. Adapun untuk penelitian selanjutnya diharapkan dapat menggunakan media atau strategi yang menarik dalam pembelajaran, sebagai salah satu cara untuk meningkatkan pemahaman, semangat, dan keterampilan siswa.
Co-Authors . Erwin Afifa, Selma Afiqah Binti Abd Latif Agik Suprayogi Agus Hadi Santosa Wargadipura Agus Wijaya Ahmad Arif Amin Ainul Khadija Saleema Amelia Putri, Yusika Amir S. Madjid, Amir S. Angesti, Shavrillia Anhu Raja Anita Esfandiari Anita Rahmayanti Annisa Rofiqoh Syafikriatillah Annita Vury Nurjunitar Antonius H. Pudjiadi Ardi Sandriya Arni Fitri Bambang Pontjo Priosoeryanto Bambang Supriyatno Basrul Hanafi Beata LYL Ayu Budianto Panjaitan Carina Khairunnisa D Ardiansyah D U Rahmiati Damiana Rita Ekastuti Deni Noviana Deny Setyo Wibowo Devi Paramitha Dina Zuhdina Rahman Dwi Endrawati Dwi Gustiono Dwi Utari Rahmiati E Fitriana Ega Iftahul Rizky Ekowati Handharyani Elok Budi Retnani Elvira Adyaputri Erwin Erwin Erwin Erwin Erwin Erwin Eva Harlina Fadhilah Nur Annisa Febryanto, Agung Fitri, Arni Diana Galih Satria Kusumanto Harits Abdullah Munir Hastjarjo Fleuryantari Helny Rosita Supriadi Helny Rosita Supriadi Heryudianto Vibowo Himah Nuradilah I Gusti Agung Ngurah Arphan Eka Putra I Gusti Ngurah Sudisma IETJE WIENTARSIH Iman, Bintang Nurul Intan Khoirunnisa Irda Khaeriyah Irza Sukmana Jessica Anggun Safitri Kholis Afidatunnisa Ki Agus Dahlan Kiagus Dahlan Kiagus Dahlan Kiagus Dahlan Laras Weningtyas Lijar Pastilah Lina Noviyanti Sutardi Liza Oktafani M. Fakhrul Ulum M.Luqman Hakim Martapuri Rani Wijaya Masaji Washio Maulana, M Ridha Melpa Susanti Purba Melpa Susanti Purba Mokhamad Fakhrul Ulum, Mokhamad Muhammad Abhi Purnomosidi Muhammad Fajrul Falah Muhammad Kamal Muhammad Redha Anshari Munar Lubis Murtiningrum, Fitria Senja Nabila Latifa Hafizsha Nadya Amanda Putri Najma Hayati Ni Rai Fertilini Hanira Jelantik Nindya Dwi Utami Nur Fitri Utami Nuzula Ramadian Peter Ian Limas Rachmi Ridho Raden Roro Soesatyoratih Rahmi, Riska Asria Sa'adatur Rahul Ajie Saksena Ramadian, Nuzula Ravi, Sugganya Retno Wulansari Riana Nurul Maulani Riki Siswandi Riski Rostantinata Rismala Dewi Sardimi, Sardimi Selma Afifa Selma Laily Nur Afifa Selma Laily Nur Afifah Septi Nurcholida Sari Shavrillia Angesti Shavrillia Inovanny Angesti Shayrilia Ivanovanny Angesti Sitaria Siallagan Siti Zaenab Sri Rezeki Srihadi Agungpriyono Subangkit, Mawar Sugganya Ravi Surawan, Surawan Sus Derthi Widhyari Sus Derthi Widyari TATI NURHAYATI Tri Isyani Tungga Dewi Tytha Nadhifa Winarto Viyata Pratiwi Risky Yuliani Suparmin Zultinur Muttaqin