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All Journal HAYATI Journal of Biosciences Hemera Zoa Journal of Food and Pharmaceutical Science Jurnal Sain Veteriner Buletin Peternakan Jurnal Veteriner Jurnal Pengabdian Pada Masyarakat Indonesian Journal of Chemistry Buletin Anatomi dan Fisiologi (Bulletin of Anatomy and Physiology) Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Veterinary Sciences) Vitek : Bidang Kedokteran Hewan IGKOJEI: Jurnal Pengabdian Masyarakat Mejuajua Jurnal Kedokteran Hewan Prosiding Seminar Hasil Penelitian dan Pengabdian Kepada Masyarakat Journal of Food and Pharmaceutical Sciences
Claude Mona Airin
Departemen Fisiologi Fakultas Kedokteran Hewan Universitas Gadjah Mada, Yogyakarta, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Public Health Social Sciences Veterinary Other

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Kadar Hormon Prolaktin Pada Kambing Peranakan Ettawa,Sapera dan Saanen Pada Berbagai Status Fisiologi Sarmin Sarmin; Irkham Widiyono; Devita Anggraeni; Claude Mona Airin; Pudji Astuti
Jurnal Sain Veteriner Vol 40, No 3 (2022): Desember
Publisher : Fakultas Kedokteran Hewan Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.76207

Abstract

  This study examines the prolactin hormone profile in Etaawa, Sapera and Saanen lactating goats, adult females, pregnant does, and yearlings. This study used a total of 80 randomly selected goats with details of 26 Ettawa Crossbreed goats (eight lactating, six adult females, six pregnant, and six heifers), 32 Sapera goats (eight lactating, six adult females, twelve pregnant, and six yearlings) and 22 Saanen goats (five lactating, four adult females, six pregnant and yearling). All goats were declared clinically healthy. Blood sampling was performed through the jugular vein in each animal; then, serum was analyzed with an Enzyme-linked immunosorbent assay (ELISA) to prolactin concentration. High prolactin concentrations were found in Saanen goats in pregnant physiological status compared to Sapera and Ettawa crossbreed goats. 
Profil Total Bilirubin, Aktivitas Alanine Transaminase dan Total Protein Domba Garut pada Umur dan Status Fisiologis yang Berbeda Sarmin Sarmin; Pudji Astuti; Claude Mona Airin; Nur Adianto
Jurnal Veteriner Vol 23 No 3 (2022)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19087/jveteriner.2022.23.3.432

Abstract

The purpose of this study was to examine the profiles of total bilirubin, ALT activity, and total protein in Garut sheep at different ages and physiological stasus. A total of 36 head of Garut sheep with various physiological conditions (ewe, ram, female suckling lamb, male suckling lamb, female postweaning lamb, male postweaning lamb, young ram aged six month, young ram aged one, pregnant ewe, and lactating ewe) was used in this research. Blood samples were taken through the jugular vein in the morning before the sheep were fed. Then, the values of total bilirubin, alanine aminotransferase (ALT), and total protein were analyzed. The mean total bilirubin value of Garut sheep was 0.59 ± 0.49 mg/dL, influenced by age and not affected by sex or physiological status. The total bilirubin value of ewe lambs was the highest (1.85 ± 0.87 mg/dL) compared to the total bilirubin value at other ages. The average value of ALT activity in garut sheep was 18.84 ± 6.56 U/L, which is influenced by age but not affected by physiological status or gender. The value of ALT activity in female suckling lamb was the lowest (7.03 ± 0.81 U/L) compared to ALT activity at other ages. The average total protein of Garut sheep was 6.48 ± 0.83 (g/dL), which was affected by age but not affected by sex or physiological status. The lowest total protein was found in female suckling lamb (.51 ± 0.59 g/dL) compared to total protein values at other ages. It was concluded that age affected the values of total bilirubin, ALT activity, and total protein in Garut sheep. Therefore, the age of Garut sheep should be considered in the interpretation of total bilirubin, ALT activity, and total protein.
ANALYSIS OF APOLIPOPROTEIN-B (APO-B) GENE IN ATHEROSCLEROSIS MICE GIVEN CURCUMINOID EXTRACT OF ZANTHORRIZA IN ORAL Trini Susmiati; Rini Widayanti; Aris Purwantoro; Claude Mona Airin; Sarmin Sarmin
Jurnal Kedokteran Hewan Vol 13, No 2 (2019): June
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (484.877 KB) | DOI: 10.21157/j.ked.hewan.v13i2.10219

Abstract

The aim of this study was to investigate the apolipoprotein-B (apo-B) gene in atherosclerosis mice which were orally given curcuminoid extract of Curcuma xanthorriza. A total number of 30 white mice were split into 6 groups, the first group considered as control (without any treatment), second group as atherogenic feed control, the third group as extract control, while the fourth, fifth and sixth groups as atherogenic feed and curcuminoid Curcuma xanthorriza extract group treated with 5 mg/mouse, 10 mg/mouse and 15 mg/ mouse, respectively for three months. The blood samples were taken from all six groups for the deoxyribonucleic acid (DNA) analysis using total DNA isolation, DNA amplification with polymerase chain reaction (PCR), and DNA sequencing. The data analysis showed that 374 bp nucleotide sequence gen of apo-B from Rattus norvegicus in groups B, C, D, E, and F did not cause any changes in genes. The analysis showed the sequence of apo-B Rattus norvegicus gene in the treatment group was apparently identical with that of Rattus norvegicus group A as the control group without treatment. As conclusion, the administration of curcuminoid zanthorrizza to atherosclerosis mice did not change the gene structure of apo-B 100.
THE EFFECTIVENESS OF ETHANOL EXTRACT OF BINAHONG LEAVES ON DIABETIC WOUND HEALING Devita Anggraeni; Claude Mona Airin; Slamet Raharjo
Jurnal Kedokteran Hewan Vol 11, No 4 (2017): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (639.445 KB) | DOI: 10.21157/j.ked.hewan.v11i4.6562

Abstract

This research aimed to study the effectiveness of ethanol extract of binahong leaves on blood glucose, insulin, blood chemical profiles (serum glutamic pyruvate transaminase=SGPT, serum glutamic oxaloacetic transaminase=SGOT, ureum, and creatinine), and skin histopathology in diabetic rat. A total of 20 male Wistar rats aged 3 months (± 250 gram) were divided into five groups, with four rats in each group. Group I (non-diabetic control) was injected with 0.1 M sodium citrate buffer, while group II (diabetic control), III, IV, and V were injected with single dose of Streptozotocin (STZ) at dose 40 mg/kg intraperitoneally (IP). One week after the injection, the dorsal skin of the rats were excised. Group I and II were given cream topically and 1% NaCMC orally, group III was given 50% ethanol extract of binahong leaves (EEB) topically and 1% NaCMC orally, group IV was given cream topically and EEB 300 mg/kg orally, and group V was given 50% EEB topically and EEB 300 mg/kg orally. These treatments were continued for 14 days. Blood samples were obtained at the end of study to examine blood glucose, insulin, and blood chemical profiles (SGOT, SGPT, ureum, and creatinine). Examination of skin histopathology and leukocyte count were also done. The result showed that blood glucose, insulin, SGOT, SGPT, and ureum level of diabetic rats given topical or oral EEB did not significantly different from diabetic control group, even though blood glucose, insulin, SGOT, SGPT, and ureum level of diabetic rats given topical and oral EEB were found lower compared to diabetic control group. Administration of EEB 300 mg/kg orally in diabetic rats could lower creatinine level significantly (P0.05). Histopathological examination of dorsal skin of diabetic rats which were given EEB topically showed the decrease of fibroblast proliferation, leukocyte infiltration, and hemorrhage in dermis area. Leukocyte count on skin tissue was significantly lower (P0.05) in diabetic rats given EEB. In conclusion, topical or oral administration of EEB can help healing process in diabetic wound.
The Effect of Metanolic Extract and Ethyl Acetate Fraction of Kepel Fruits to Lipid Peroxide Concentration in Liver of CCl4-induced Rat Mitsalina Fildzah Arifah; Sudibyo Martono; Sugeng Riyanto; Claude Mona Airin
Journal of Food and Pharmaceutical Sciences Vol 7, No 3 (2019): J. Food Pharm. Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.661

Abstract

Accumulation lipid peroxidation can lead to the formation of malondialdehyde to generatefree radicals. Antioxidant will minimize free radical related health problems, such as naturalantioxidant from meat of kepel (Stelechocarpus burahol) (Blume) Hook. F. & Thompson) fruits.Antioxidant activities of methanol extracts and acetate ethyl fractions meat of kepel fruits calculatedprofile of malondialdehyde concentration (ng/mL) in CCl4 induced acute liver toxicity in femaleSprague Dawley rats using ELISA competitively method. All of groups induced CCl4 i.p. at 0 h, exceptuntreated and solvent control group, then vitamin C , methanol extracts and acetate ethyl fractionsp.o. once daily for 72 h. Identification of secondary metabolite was using phytochemical screeningand Thin Layer Chromatography (TLC). Liver weighed and calculated relative organ weight (ROW)of liver, then all of data analyzed using statistic tests, One Way ANOVA and Kruskall Wallis. Thisstudy showed methanol extracts can decrease MDA concentration, ALT and AST were more potent(significantly p<0.05) than acetate ethyl fractions and vitamin C. The TLC analysis identified methanolextracts have same polarity with quercetin (Rf = 0,26) and acetate ethyl fractions showed otherflavonoid class, except rutin and quercetin. ROW of acute liver toxicity in rats increased significantlyin CCl4 and vitamin C groups.
The Effect of Methanolic Extract and Ethyl Acetate Fraction of Kepel Fruit (Stelechocarpus burahol) to α-Glutathione S-Transferase Enzyme Concentration of Rat Liver and Blood Induced by CCl4 Yusuf Rabbani; Claude Mona Airin; Sugeng Riyanto
Journal of Food and Pharmaceutical Sciences Vol 8, No 2 (2020): J. Food Pharm. Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.691

Abstract

Degenerative diseases are mostly caused by high free radical concentrations in the body. Kepel fruit(Stelechocarpus burahol) is known to contain flavonoid compounds, a class of compounds that has free radicalscavenging activity in the body and could affect the activity of antioxidant enzymes. There have been reportsthat methanolic extract and ethyl acetate fractions of Kepel fruit have the lowest IC50 values, compared toextracts or fractions which are made using other organic solvents, on in vitro assays so that flavonoids aresuspected as responsible compounds to the free radical scavenging activity. This study aimed to identify thepresence of flavonoid content in methanolic extract and the fraction of ethyl acetate of Kepel fruit and also itseffect on rat alpha Glutathione S-Transferase (α-GST) enzyme concentration for the function to prevent hepaticcell damage due to carbon tetrachloride exposure. The identification of flavonoids content used a series ofcolor chemical reaction tests and thin layer chromatography that used silica gel 60F254 as the solid phase andmixture of ethyl acetate, formic acid, glacial acetic acid, and water (100: 11 : 11: 20 v/v) as the mobile phase.This study used 30 Sprague-Dawley female rats (age 2-3 months) that were grouped into 5 groups as solventcontrol (CMC-Na) group, negative control (CCl4) group, positive control (vitamin C) group, methanolic extractgroup, and ethyl acetate fraction group. All groups were induced with carbon tetrachloride (CCl4) compoundsexcept for the CMC-Na solvent control group. Blood sampling at 0 h, 24 h, and 72 h, while liver sampling at 24h and 72 h, with 3 samples each group. The analysis of rat α-GST enzyme concentrations used theEnzyme-linked Immunosorbent Assay (ELISA) method. Based on the phytochemical test, the methanolicextract and the ethyl acetate fraction of Kepel fruit have been identified contains flavonoids compound. Basedon the in vivo study, the positive control group's α-GST enzyme concentration was decreased, while thenegative control group's α-GST enzyme concentration was increased. Administration of methanolic extractand ethyl acetate fraction also decreased both liver and blood rat α-GST enzyme concentrations, althoughwithout significant correlation, and still could prevent the hepatic cell damage due to carbon tetrachlorideexposure.
Sargassum crasifolium Extract Could Prevent the Decrese in the Thyroxine Hormone and the Body Weight Loss of Javanese Randu Goats during Transportation Claude Mona Airin; Amelia Hana; Sarmin; Pudji Astuti; Amir Husni; Rusyda Nurshitaningrum
Journal of Food and Pharmaceutical Sciences Vol 8, No 3 (2020): J.Food.Pharm.Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.850

Abstract

Thyroxine hormone (T4) was one of the hormones related to metabolism rate. Animal transportation could be stressor interfering metabolism. Sargassum crasifoium was one of brown algae species that contained some important nutrients and also flavonoids. The study aimed at finding out the effect of the Sargassum on the decrase in thyroxine hormone and body weight loss. It used 9 Javanese Randu goats that were classified into 3 treatment groups. Group I served as control, Group II was treated with 450 mg/kg BW of Sargassum estract and Group III was treated with vitamin B1. All of the goats were transported for 12 hours using pickup truck at the speed of 60 km/hour. Blood samples were drawn before the transportation, during loading, 6 hours after the transportation and at the end of the transportation, while the body weight of the goats was weighed before and after the transportation. The results of the study showed that the T4 hormone decreased in the Group I and increased in the Group III during the transportation, while it was stable in the Group II. The biggest percentage of the body weight loss took place to the Group III (0.13%), while the smallest percentage took place to the Group II (0.063%). Statistical analysis showed that the Sargassum extract did not have any significant effect (p>0.05) on both the thyroxine hormone and the body weight loss during the transportation. Based on the results of the study it could be concluded that the Sargassum extract could stabilize the thyroxine hormone during the transportation so that it could prevent the body weight loss
Pemberdayaan Masyarakat Melalui Pelatihan Pembuatan Sabun Padat Alami Berbasis Daun Kelor dan Minyak Zaitun Larasati, Dwi; Rahayu, Budi; Okta Viyani, Ari; Sunarsih, Tri; Sarmin, Sarmin; Mona Airin, Claude; Soffan, Alan; Puji Astuti, Endah; Fit Ari Shanti, Elvika
Mejuajua: Jurnal Pengabdian pada Masyarakat Vol. 4 No. 2 (2024): Desember 2024
Publisher : Yayasan Penelitian dan Inovasi Sumatera (YPIS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/mejuajuajabdimas.v4i2.209

Abstract

Kegiatan pemberdayaan masyarakat melalui pelatihan pembuatan sabun padat alami berbasis daun kelor dan minyak zaitun bertujuan untuk meningkatkan pengetahuan dan keterampilan masyarakat dalam memproduksi produk ramah lingkungan dan bernilai ekonomis. Pelatihan ini dilaksanakan pada 8 November 2024 dengan melibatkan peserta dari berbagai latar belakang. Metode yang digunakan adalah pendekatan praktis dengan memberikan materi teori dan diikuti dengan praktik langsung pembuatan sabun. Teknik analisis dilakukan dengan membandingkan hasil evaluasi sebelum dan setelah pelatihan serta melakukan observasi terhadap produk yang dihasilkan. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan dan keterampilan peserta sebesar 21,16%, dengan produk sabun alami yang dihasilkan memiliki kualitas yang baik dalam hal kesehatan kulit dan ramah lingkungan. Pelatihan ini berhasil mencapai tujuan pemberdayaan masyarakat dan dapat menjadi dasar untuk pengembangan produk yang lebih luas serta peluang usaha bagi masyarakat.
Karakterisasi Gejala Klinis pada Kucing dengan Gangguan Gastrointestinal yang Disertai Leukopenia Ramadhani, Mungky Ema; Yanuartono, Yanuartono -; Indarjulianto, Soedarmanto; Purnamaningsih, Hary; Widyarini, Sitarina; Airin, Claude Mona
Jurnal Sain Veteriner Vol 43, No 1 (2025): April
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.70783

Abstract

Abstract               Gastrointestinal is one of the digestive system disorders in cats that can be characterized by leucopenia. This study aimed to evaluate the clinical symptoms of cats with digestive disorders with leucopenia. This study used 30 cats of various breeds, ages, and genders that had symptoms of digestive disorders with leucopenia. All cats were physically and laboratory examined for hematology. The data obtained were analyzed descriptively. The results showed 18/30 (60%) cats aged 1-6 months, 9/30 (30%) aged 7-12 months, and 3/30 cats (10%) aged >12 months, had gastrointestinal disorders with leucopenia. Leucopenia conditions were more common in male cats (53.3%) than female cats (46.7%). Cats with leucopenia, 10 (33.3%) with a leukocyte count <1,000 cells/mm3, 14 (46.7%) with a leukocyte count of 1,001-2,500 cells/mm3 and 6 (20%) with a leukocyte count of 2,501-<5,500 cells/mm3. Clinical symptoms found in this study included lethargy, anorexia, fever, dehydration, diarrhea, vomiting, halitosis, hypersalivation, anemia, lacrimation, epistaxis and jaundice. Concluded that gastrointestinal disorders with leucopenia were more common in young cats and male cats. Clinical symptoms of lethargy, anorexia, fever, dehydration, diarrhea and vomiting, can be used as a reference to determine the diagnosis of gastrointestinal disorders with leucopenia in cats. Key words:  cats; clinical sign; gastrointestinal; leucocytes
ANALYSIS OF APOLIPOPROTEIN-B (APO-B) GENE IN ATHEROSCLEROSIS MICE GIVEN CURCUMINOID EXTRACT OF ZANTHORRIZA IN ORAL Susmiati, Trini; Widayanti, Rini; Purwantoro, Aris; Airin, Claude Mona; Sarmin, Sarmin
Jurnal Kedokteran Hewan Vol 13, No 2 (2019): June
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v13i2.10219

Abstract

The aim of this study was to investigate the apolipoprotein-B (apo-B) gene in atherosclerosis mice which were orally given curcuminoid extract of Curcuma xanthorriza. A total number of 30 white mice were split into 6 groups, the first group considered as control (without any treatment), second group as atherogenic feed control, the third group as extract control, while the fourth, fifth and sixth groups as atherogenic feed and curcuminoid Curcuma xanthorriza extract group treated with 5 mg/mouse, 10 mg/mouse and 15 mg/ mouse, respectively for three months. The blood samples were taken from all six groups for the deoxyribonucleic acid (DNA) analysis using total DNA isolation, DNA amplification with polymerase chain reaction (PCR), and DNA sequencing. The data analysis showed that 374 bp nucleotide sequence gen of apo-B from Rattus norvegicus in groups B, C, D, E, and F did not cause any changes in genes. The analysis showed the sequence of apo-B Rattus norvegicus gene in the treatment group was apparently identical with that of Rattus norvegicus group A as the control group without treatment. As conclusion, the administration of curcuminoid zanthorrizza to atherosclerosis mice did not change the gene structure of apo-B 100.
Co-Authors . Harimurti . Sunaryanto Agustina Dwi Wijayanti Alfarisa Nururrozi Alnita Baaka Alvina Nur Aini Amelia Hana Amelia Hana Amelia Hana Amelia Hana Amelia Hana Amelia Hana Amelia Hana Amelia Hana Amelia Hana Amelia Hana Amelia Hana Amelia Hana Amelia Hana Amelia Hana Amir Husni Amir Husni Amrullah Anindito Antasiswa Windraningtyas Rosetyadewi Arifah, Mitsalina Fildzah Aris Purwantoro Aris Purwantoro Asmarani Kusumawati Bambang Sutrisno Budi Rahayu, Budi Christin Marganingsih Santosa Daniswari, Priyanka Primananda Devita Anggraeni Devita Anggraeni Devita Anggraeni Dhasia Ramandani, Dhasia Didik Yulianto Divani, Adelia Lintang Dwi Larasati Dwi Larasati, Dwi Dwi Nurhayati, Dwi Elvika Fit Ari Shanti, Elvika Fit Ari Endah Puji Astuti, Endah Puji Endang Baliarti Fit Ari Shanti, Elvika Hanum, Maulida Selma Hary Purnamaningsih HERA MAHESHWARI Herawati, Okti Indriani, Rizka Irkham Widiyono Irma Dian Nurani Khrisdiana Putri LUTHFIRALDA SJAHFIRDI Maulida Selma Hanum Michael Haryadi Wibowo Muhammad Fariz Ash Shiddiq Muhammad Naufal Prayitno Putra Novia Nur Aini Nugroho, Fatah Nur Adianto Nuraini Rachmawati Nuraini Rahmawati Okid Parama Astirin Okta Viyani, Ari Paryuni, Alsi Dara Prabowo Purwono Putro Prabowo Purwono Putro Pradityo Yoga Wibowo Priyo Sambodo Pudji Astuti Pudji Astuti Pudji Astuti Pudji Astuti Pudji Astuti PUDJI ASTUTI Pudji Astuti Pudji Astuti Pudji Astuti Pudji Astuti Pudji Astuti Pudji Astuti Pudji Astuti Puji Astuti, Endah Purwaningsih - Purwaningsih Purwaningsih Raden Rara Amelia Hana Ramadhani, Mungky Ema Refika Melina Putri Rini Widayanti Rini Widayanti Risa Ummami Risa Ummami Rizka Indriani Rizki Fitrawan Yuneldi Rochmah, Jayanti Astridya Rusyda Nurshitaningrum Sarmin - Sarmin . Sarmin Sarmin Sarmin Sarmin Sarmin Sarmin Sarmin Sarmin Sitarina Widyarini Slamet Raharjo Slamet Raharjo Slamet Widiyanto Soedarmanto Indarjulianto Soedarmanto Indarjulianto Soffan, Alan Sudibyo Martono Sugeng Riyanto Sugeng Riyanto Suparni Setyowati Rahayu Tauhid Tauhid Tri Joko Raharjo Tri Sunarsih Tri Wahyu Pangestiningsih Trini Susmiati Viyani, Ari Okta Wisnu Nurcahyo Yanuartono, Yanuartono yanuartono, yanuartono - Yuda Heru Febrianto Yuda Heru Fibrianto Yuda Heru Fibrianto Yuda Heru Fibrianto Yuda Heru Fibrianto Yuneldi, Rizki Fitrawan Yusuf Rabbani Zahra, Nafisa Az